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The map label for this gene is 218709168

Identifier: 218709168

GI number: 218709168

Start: 1243473

End: 1244660

Strand: Reverse

Name: 218709168

Synonym: VS_1175

Alternate gene names: NA

Gene position: 1244660-1243473 (Counterclockwise)

Preceding gene: 218709169

Following gene: 218709165

Centisome position: 37.72

GC content: 46.8

Gene sequence:

>1188_bases
GTGGTTTGCTCGAAAAAAAGTGTGCTAATCTTACGGCAACTCAACTACGAGATAAAAACTACAATGAAAATTTTCAGCAA
CTTCGAAAGCGGCAACATTCACGTCGTTTCAGCAGATTCACCACAAAACATTCAACTGACTATTCCAGCGGATAACCAAA
CTGAAATCGCACAATGGTTTCATTTCCGCTTAGAAAGTGAAGCTCAACAAGCTCACCACTTTGAAATCGGCCAATTGGCA
ACATCTGCCTACCCTGAAGGCTGGAAAGATTATGATGTGGTTGCATCGTATGACCGTGAAGAGTGGTTCCGTATTCCATC
TCAATTCGATGGCGACACTTTAAGCTTTGATATCATTCCTGAACACGATTCAATGTACTTCGCGTACTTCGCACCGTATT
CATACGATCGTCATCAAGATCTCTTGCACAGTGCTCAAACGCACCCTGCTTGTAAGCTAGAAACTCTGGGCCATACGTTA
GATAACAACGACATCACTTTGCTAACCATCGGTGAGCCAAGTGCAGAGAAGAAAAACATCTGGGTTATTGGTCGCCAACA
TCCGGGCGAGACCATGGCTGAATGGCTGATCGAAGGTCTGCTACAACGCTTGCTTGATGAAACAGACACCGTCGGTCGTT
CACTTCTAGACAGCGTTGTATTCCGCGTTGTACCTAACATGAACCCAGACGGCAGTATCCGTGGTCACCTACGCACTAAC
GGTATTGGCGTTAACCTAAACCGTGAATGGCAGTCACCTTCTATGGAACGCAGCCCTGAGGTTTTCTTTGTTCGCGAGCG
CATGCTAGAAACTGGCGTTGACCTTTGTCTAGACATTCACGGCGACGAAGCAATCCCATATAACTTTGTTGCTGGTAGCG
AAGGCACACCTTCATACAACGAGCGCATTGCAAAACTAGAGAATCACTTCAAGCAAGCTCTTCTGACTATCACGCCAGAG
TTCCAAGATGAATTTGGCTACGATAAAGACGAACCGGGCAAAGCAAATATGACCGTCGGCACAAACTGGATCGGCGAACA
GTTCAAGTGTTTGGCATACACTGTCGAGATGCCATTTAAAGATCACATCAGCCACGCTGACGAACTGTACGGTTGGTCTC
CAGAGCGCAGTGTTGCATTTGGTCACGACATGCTAGCAGCGGTTTGGGCAACAGTCGACGAGCTATAA

Upstream 100 bases:

>100_bases
AACGTCGATAGCTCAAAGTTAACCGTTAAATAGCTGTCGATTTAAAAGTAGGCAGCTAAAAAACAGATAGCTGAAATAAC
ATCTTATTACGATTTAGTTA

Downstream 100 bases:

>100_bases
GACGAAGCAAACTTGTTAGTTTTTCCTTAGAGACAGTTTGTCTTTAGAAGTAGTTTGTTCATTTTGTTCATATAGATAAC
AAAGCCCAGCACTCGTCAAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MVCSKKSVLILRQLNYEIKTTMKIFSNFESGNIHVVSADSPQNIQLTIPADNQTEIAQWFHFRLESEAQQAHHFEIGQLA
TSAYPEGWKDYDVVASYDREEWFRIPSQFDGDTLSFDIIPEHDSMYFAYFAPYSYDRHQDLLHSAQTHPACKLETLGHTL
DNNDITLLTIGEPSAEKKNIWVIGRQHPGETMAEWLIEGLLQRLLDETDTVGRSLLDSVVFRVVPNMNPDGSIRGHLRTN
GIGVNLNREWQSPSMERSPEVFFVRERMLETGVDLCLDIHGDEAIPYNFVAGSEGTPSYNERIAKLENHFKQALLTITPE
FQDEFGYDKDEPGKANMTVGTNWIGEQFKCLAYTVEMPFKDHISHADELYGWSPERSVAFGHDMLAAVWATVDEL

Sequences:

>Translated_395_residues
MVCSKKSVLILRQLNYEIKTTMKIFSNFESGNIHVVSADSPQNIQLTIPADNQTEIAQWFHFRLESEAQQAHHFEIGQLA
TSAYPEGWKDYDVVASYDREEWFRIPSQFDGDTLSFDIIPEHDSMYFAYFAPYSYDRHQDLLHSAQTHPACKLETLGHTL
DNNDITLLTIGEPSAEKKNIWVIGRQHPGETMAEWLIEGLLQRLLDETDTVGRSLLDSVVFRVVPNMNPDGSIRGHLRTN
GIGVNLNREWQSPSMERSPEVFFVRERMLETGVDLCLDIHGDEAIPYNFVAGSEGTPSYNERIAKLENHFKQALLTITPE
FQDEFGYDKDEPGKANMTVGTNWIGEQFKCLAYTVEMPFKDHISHADELYGWSPERSVAFGHDMLAAVWATVDEL
>Mature_395_residues
MVCSKKSVLILRQLNYEIKTTMKIFSNFESGNIHVVSADSPQNIQLTIPADNQTEIAQWFHFRLESEAQQAHHFEIGQLA
TSAYPEGWKDYDVVASYDREEWFRIPSQFDGDTLSFDIIPEHDSMYFAYFAPYSYDRHQDLLHSAQTHPACKLETLGHTL
DNNDITLLTIGEPSAEKKNIWVIGRQHPGETMAEWLIEGLLQRLLDETDTVGRSLLDSVVFRVVPNMNPDGSIRGHLRTN
GIGVNLNREWQSPSMERSPEVFFVRERMLETGVDLCLDIHGDEAIPYNFVAGSEGTPSYNERIAKLENHFKQALLTITPE
FQDEFGYDKDEPGKANMTVGTNWIGEQFKCLAYTVEMPFKDHISHADELYGWSPERSVAFGHDMLAAVWATVDEL

Specific function: Unknown

COG id: COG2866

COG function: function code E; Predicted carboxypeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI222352158, Length=310, Percent_Identity=30.3225806451613, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI31657119, Length=296, Percent_Identity=32.0945945945946, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI190194403, Length=374, Percent_Identity=27.2727272727273, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI120444924, Length=290, Percent_Identity=28.2758620689655, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI170763513, Length=289, Percent_Identity=29.0657439446367, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI78482633, Length=185, Percent_Identity=29.7297297297297, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI118421091, Length=185, Percent_Identity=29.7297297297297, Blast_Score=80, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI115533904, Length=360, Percent_Identity=26.3888888888889, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI193202888, Length=320, Percent_Identity=28.125, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24641847, Length=313, Percent_Identity=30.9904153354633, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI28571179, Length=313, Percent_Identity=30.9904153354633, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI161077807, Length=313, Percent_Identity=30.9904153354633, Blast_Score=129, Evalue=5e-30,
Organism=Drosophila melanogaster, GI24641845, Length=313, Percent_Identity=30.9904153354633, Blast_Score=128, Evalue=6e-30,
Organism=Drosophila melanogaster, GI24651466, Length=243, Percent_Identity=28.8065843621399, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000834 [H]

Pfam domain/function: PF00246 Peptidase_M14 [H]

EC number: NA

Molecular weight: Translated: 45069; Mature: 45069

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVCSKKSVLILRQLNYEIKTTMKIFSNFESGNIHVVSADSPQNIQLTIPADNQTEIAQWF
CCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEECCCCCHHHHHHH
HFRLESEAQQAHHFEIGQLATSAYPEGWKDYDVVASYDREEWFRIPSQFDGDTLSFDIIP
HHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCHHEECCCHHHHHCCCCCCCCCEEEEEEEE
EHDSMYFAYFAPYSYDRHQDLLHSAQTHPACKLETLGHTLDNNDITLLTIGEPSAEKKNI
CCCCEEEEEECCCCCCHHHHHHHHHCCCCCEEEHHHCCCCCCCCEEEEEECCCCCCCCCE
WVIGRQHPGETMAEWLIEGLLQRLLDETDTVGRSLLDSVVFRVVPNMNPDGSIRGHLRTN
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEC
GIGVNLNREWQSPSMERSPEVFFVRERMLETGVDLCLDIHGDEAIPYNFVAGSEGTPSYN
CEEEEECCCCCCCCCCCCCCEEHHHHHHHHCCCEEEEEECCCCCCCEEEEECCCCCCHHH
ERIAKLENHFKQALLTITPEFQDEFGYDKDEPGKANMTVGTNWIGEQFKCLAYTVEMPFK
HHHHHHHHHHHHHHEEECCCHHHHCCCCCCCCCCCEEEECCCHHCCCEEEEEEEEECCCH
DHISHADELYGWSPERSVAFGHDMLAAVWATVDEL
HHHCHHHHHCCCCCCCCEEHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVCSKKSVLILRQLNYEIKTTMKIFSNFESGNIHVVSADSPQNIQLTIPADNQTEIAQWF
CCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEECCCCCHHHHHHH
HFRLESEAQQAHHFEIGQLATSAYPEGWKDYDVVASYDREEWFRIPSQFDGDTLSFDIIP
HHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCHHEECCCHHHHHCCCCCCCCCEEEEEEEE
EHDSMYFAYFAPYSYDRHQDLLHSAQTHPACKLETLGHTLDNNDITLLTIGEPSAEKKNI
CCCCEEEEEECCCCCCHHHHHHHHHCCCCCEEEHHHCCCCCCCCEEEEEECCCCCCCCCE
WVIGRQHPGETMAEWLIEGLLQRLLDETDTVGRSLLDSVVFRVVPNMNPDGSIRGHLRTN
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEC
GIGVNLNREWQSPSMERSPEVFFVRERMLETGVDLCLDIHGDEAIPYNFVAGSEGTPSYN
CEEEEECCCCCCCCCCCCCCEEHHHHHHHHCCCEEEEEECCCCCCCEEEEECCCCCCHHH
ERIAKLENHFKQALLTITPEFQDEFGYDKDEPGKANMTVGTNWIGEQFKCLAYTVEMPFK
HHHHHHHHHHHHHHEEECCCHHHHCCCCCCCCCCCEEEECCCHHCCCEEEEEEEEECCCH
DHISHADELYGWSPERSVAFGHDMLAAVWATVDEL
HHHCHHHHHCCCCCCCCEEHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8320209 [H]