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The map label for this gene is moaB [H]

Identifier: 218708980

GI number: 218708980

Start: 1019679

End: 1020191

Strand: Direct

Name: moaB [H]

Synonym: VS_0986

Alternate gene names: 218708980

Gene position: 1019679-1020191 (Clockwise)

Preceding gene: 218708979

Following gene: 218708981

Centisome position: 30.91

GC content: 46.39

Gene sequence:

>513_bases
ATGGGTCACGCAGAAAGCAAATTTCAAGCAGCGAACATTGCAGTATTAACGGTTTCAGATACTCGTACAGAAGAAAATGA
CACGTCAGGTGGTTACCTAGCTGAGCATGCTAAAGAAGCTGGTCACAACGTGGTTGATAAGCAAATTGTTATCGATGACA
TGTACAAGATCCGTGCGATCGTATCTCAGTGGATTGCTGATGACAGCGTCCAAGCGATCATGATCACTGGTGGTACGGGT
TTTACTTCTCGTGATAGCACCCCAGAAGCACTTAAGCCACTGTTCGACAAAGAAGTAGAAGGCTTTGGTGAGCTATTCCG
CCAAGTGTCTTACGAAGAGATTGGTACTTCGACGATTCAATCGCGTGCAATCGCGGGTTTTGCTAACCACACGGTTATCT
TTGCGATGCCAGGTTCTACAGGTGCGTGCCGTACAGGTTGGACTAAGATCATCAAGCAACAGATGGATGCTAGCCACCGT
CCTTGTAACTTCATGCCACATCTTTCTGTATAA

Upstream 100 bases:

>100_bases
CTTCCCCCTCGCCGCGATTAAAACGCTTTTATCTCGAACAAAATTTAATCACGAAAGGTCAACACGCCCTAATAATTAAA
AAATTTATATAGGTGAACAA

Downstream 100 bases:

>100_bases
GGTGGTTTGAGCATGAGCCAATTTACCCACATTAACGCGTCTGGCGAAGCGAACATGGTCGATGTATCGGCTAAAGCGGA
AACTGTACGCGAAGCGAGAG

Product: molybdenum cofactor biosynthesis protein B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 170; Mature: 169

Protein sequence:

>170_residues
MGHAESKFQAANIAVLTVSDTRTEENDTSGGYLAEHAKEAGHNVVDKQIVIDDMYKIRAIVSQWIADDSVQAIMITGGTG
FTSRDSTPEALKPLFDKEVEGFGELFRQVSYEEIGTSTIQSRAIAGFANHTVIFAMPGSTGACRTGWTKIIKQQMDASHR
PCNFMPHLSV

Sequences:

>Translated_170_residues
MGHAESKFQAANIAVLTVSDTRTEENDTSGGYLAEHAKEAGHNVVDKQIVIDDMYKIRAIVSQWIADDSVQAIMITGGTG
FTSRDSTPEALKPLFDKEVEGFGELFRQVSYEEIGTSTIQSRAIAGFANHTVIFAMPGSTGACRTGWTKIIKQQMDASHR
PCNFMPHLSV
>Mature_169_residues
GHAESKFQAANIAVLTVSDTRTEENDTSGGYLAEHAKEAGHNVVDKQIVIDDMYKIRAIVSQWIADDSVQAIMITGGTGF
TSRDSTPEALKPLFDKEVEGFGELFRQVSYEEIGTSTIQSRAIAGFANHTVIFAMPGSTGACRTGWTKIIKQQMDASHRP
CNFMPHLSV

Specific function: Maybe involved in the biosynthesis of molybdopterin. Can bind GTP and has low GTPase activity. Can bind MPT, but has no MPT adenylyl transferase activity [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Escherichia coli, GI1787000, Length=168, Percent_Identity=64.2857142857143, Blast_Score=229, Evalue=6e-62,
Organism=Drosophila melanogaster, GI17136978, Length=151, Percent_Identity=33.7748344370861, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24638841, Length=151, Percent_Identity=33.7748344370861, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR012245
- InterPro:   IPR013484
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 18553; Mature: 18422

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS01078 MOCF_BIOSYNTHESIS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGHAESKFQAANIAVLTVSDTRTEENDTSGGYLAEHAKEAGHNVVDKQIVIDDMYKIRAI
CCCCCCCEEECCEEEEEEECCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
VSQWIADDSVQAIMITGGTGFTSRDSTPEALKPLFDKEVEGFGELFRQVSYEEIGTSTIQ
HHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRAIAGFANHTVIFAMPGSTGACRTGWTKIIKQQMDASHRPCNFMPHLSV
HHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GHAESKFQAANIAVLTVSDTRTEENDTSGGYLAEHAKEAGHNVVDKQIVIDDMYKIRAI
CCCCCCEEECCEEEEEEECCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
VSQWIADDSVQAIMITGGTGFTSRDSTPEALKPLFDKEVEGFGELFRQVSYEEIGTSTIQ
HHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRAIAGFANHTVIFAMPGSTGACRTGWTKIIKQQMDASHRPCNFMPHLSV
HHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin precursor biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]