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The map label for this gene is aroC [H]

Identifier: 218708891

GI number: 218708891

Start: 916441

End: 917526

Strand: Direct

Name: aroC [H]

Synonym: VS_0892

Alternate gene names: 218708891

Gene position: 916441-917526 (Clockwise)

Preceding gene: 218708888

Following gene: 218708893

Centisome position: 27.78

GC content: 47.05

Gene sequence:

>1086_bases
ATGGCAGGAAACAGTATCGGACAACATTTCCGCGTGACTACGTTCGGAGAAAGTCACGGTATCGCACTAGGATGTATCGT
AGATGGGTGCCCACCAGGATTAGAAATTACCGAAGCAGACCTTCAAAGAGATTTGGATCGTCGTCGCCCAGGTACTTCTC
GTTATACAACGGCTCGCCGTGAAGCGGATGAAGTAAAGATTTTATCCGGTGTATTTGAAGGCCAGACTACGGGTACTTCT
ATTGGTCTATTGATTGAAAATACAGACCAACGCTCTAAAGACTATTCCGAAATTAAAGACAAGTTCCGCCCTGGCCACGC
TGATTATACCTACCATCAAAAGTACGGTGTGCGTGATTACCGAGGTGGCGGTCGCTCTTCGGCTCGTGAAACTGCAATGC
GTGTTGCGGCAGGTGCGATTGCGAAGAAATACCTTAAGCAAGAATTTGGTGTTGAAATCCAAGCTTATCTTTCTCAAATG
GGTGATATCTCAATTGATAAAGTGGATTGGAACGAGATCGAAAACAACGCTTTCTTCTGTCCTGATGCCGACAAAGTACC
TGAATTTGACCAACTGATTCGTGACTTGCTAAAAGAAGGCAACTCGATCGGTGCGAAGATTCAAGTAGTTGCGACTAAAG
TGCCTGTAGGCCTTGGTGAGCCAATCTTTGATCGTCTAGATGCAGACATCGCGCACGCTCTAATGAGCATCAATGCGGTG
AAAGGTGTTGAGATTGGTGATGGCTTCGATGTGGTTAATCAGCGCGGTAGTGAACACCGTGATCCATTAACTCCAGAAGG
CTTCAGCAGCAACCACGCTGGCGGTATCTTAGGCGGTATTTCTACTGGTCAAGATATTGTGGCAAGCATTGCGCTTAAAC
CCACATCAAGCATTACCGTTCCTGGTGACACGATCACCAAAGACGGTGAAGCAACGCAGCTAATCACTAAAGGCCGTCAC
GATCCATGTGTTGGTATCCGTGCAGTGCCTATTGCTGAAGCGATGCTGGCTATCGTGTTGCTTGATCACTTGCTACGTCA
TCGTGGTCAAAACTTTGGTGTGACAACAGAAACGCCAAAAATCTAG

Upstream 100 bases:

>100_bases
ATAAAGCCAATATGAATTCACGAAGAATAGACAAGTAAAGCTGTTAACCCGTAGGTTTAGGAATCAAACCTTCTGCTCAA
TGGCTGATTTAGAGGAAGTA

Downstream 100 bases:

>100_bases
TTCTGCTTCGTTTTATTCAGAACAGATTTGAAACAGATTTGAGAGAAACCAAAAAGGGTTGCTTCGTAATGAAGCAACCC
TTTTTATATTCTGCGTCATT

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase [H]

Number of amino acids: Translated: 361; Mature: 360

Protein sequence:

>361_residues
MAGNSIGQHFRVTTFGESHGIALGCIVDGCPPGLEITEADLQRDLDRRRPGTSRYTTARREADEVKILSGVFEGQTTGTS
IGLLIENTDQRSKDYSEIKDKFRPGHADYTYHQKYGVRDYRGGGRSSARETAMRVAAGAIAKKYLKQEFGVEIQAYLSQM
GDISIDKVDWNEIENNAFFCPDADKVPEFDQLIRDLLKEGNSIGAKIQVVATKVPVGLGEPIFDRLDADIAHALMSINAV
KGVEIGDGFDVVNQRGSEHRDPLTPEGFSSNHAGGILGGISTGQDIVASIALKPTSSITVPGDTITKDGEATQLITKGRH
DPCVGIRAVPIAEAMLAIVLLDHLLRHRGQNFGVTTETPKI

Sequences:

>Translated_361_residues
MAGNSIGQHFRVTTFGESHGIALGCIVDGCPPGLEITEADLQRDLDRRRPGTSRYTTARREADEVKILSGVFEGQTTGTS
IGLLIENTDQRSKDYSEIKDKFRPGHADYTYHQKYGVRDYRGGGRSSARETAMRVAAGAIAKKYLKQEFGVEIQAYLSQM
GDISIDKVDWNEIENNAFFCPDADKVPEFDQLIRDLLKEGNSIGAKIQVVATKVPVGLGEPIFDRLDADIAHALMSINAV
KGVEIGDGFDVVNQRGSEHRDPLTPEGFSSNHAGGILGGISTGQDIVASIALKPTSSITVPGDTITKDGEATQLITKGRH
DPCVGIRAVPIAEAMLAIVLLDHLLRHRGQNFGVTTETPKI
>Mature_360_residues
AGNSIGQHFRVTTFGESHGIALGCIVDGCPPGLEITEADLQRDLDRRRPGTSRYTTARREADEVKILSGVFEGQTTGTSI
GLLIENTDQRSKDYSEIKDKFRPGHADYTYHQKYGVRDYRGGGRSSARETAMRVAAGAIAKKYLKQEFGVEIQAYLSQMG
DISIDKVDWNEIENNAFFCPDADKVPEFDQLIRDLLKEGNSIGAKIQVVATKVPVGLGEPIFDRLDADIAHALMSINAVK
GVEIGDGFDVVNQRGSEHRDPLTPEGFSSNHAGGILGGISTGQDIVASIALKPTSSITVPGDTITKDGEATQLITKGRHD
PCVGIRAVPIAEAMLAIVLLDHLLRHRGQNFGVTTETPKI

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788669, Length=360, Percent_Identity=77.5, Blast_Score=558, Evalue=1e-160,
Organism=Saccharomyces cerevisiae, GI6321290, Length=370, Percent_Identity=45.945945945946, Blast_Score=312, Evalue=4e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000453
- InterPro:   IPR020541 [H]

Pfam domain/function: PF01264 Chorismate_synt [H]

EC number: =4.2.3.5 [H]

Molecular weight: Translated: 39086; Mature: 38954

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1 ; PS00788 CHORISMATE_SYNTHASE_2 ; PS00789 CHORISMATE_SYNTHASE_3 ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGNSIGQHFRVTTFGESHGIALGCIVDGCPPGLEITEADLQRDLDRRRPGTSRYTTARR
CCCCCCCCCEEEEEECCCCCEEEEEEECCCCCCCEEEHHHHHHHHHHCCCCCCHHHHHHH
EADEVKILSGVFEGQTTGTSIGLLIENTDQRSKDYSEIKDKFRPGHADYTYHQKYGVRDY
HHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCCEEHHHCCCCCC
RGGGRSSARETAMRVAAGAIAKKYLKQEFGVEIQAYLSQMGDISIDKVDWNEIENNAFFC
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCEEECCCHHHHCCCEEEC
PDADKVPEFDQLIRDLLKEGNSIGAKIQVVATKVPVGLGEPIFDRLDADIAHALMSINAV
CCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
KGVEIGDGFDVVNQRGSEHRDPLTPEGFSSNHAGGILGGISTGQDIVASIALKPTSSITV
CCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHEECCCCCEEC
PGDTITKDGEATQLITKGRHDPCVGIRAVPIAEAMLAIVLLDHLLRHRGQNFGVTTETPK
CCCCCCCCCCHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
I
C
>Mature Secondary Structure 
AGNSIGQHFRVTTFGESHGIALGCIVDGCPPGLEITEADLQRDLDRRRPGTSRYTTARR
CCCCCCCCEEEEEECCCCCEEEEEEECCCCCCCEEEHHHHHHHHHHCCCCCCHHHHHHH
EADEVKILSGVFEGQTTGTSIGLLIENTDQRSKDYSEIKDKFRPGHADYTYHQKYGVRDY
HHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCCEEHHHCCCCCC
RGGGRSSARETAMRVAAGAIAKKYLKQEFGVEIQAYLSQMGDISIDKVDWNEIENNAFFC
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCEEECCCHHHHCCCEEEC
PDADKVPEFDQLIRDLLKEGNSIGAKIQVVATKVPVGLGEPIFDRLDADIAHALMSINAV
CCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
KGVEIGDGFDVVNQRGSEHRDPLTPEGFSSNHAGGILGGISTGQDIVASIALKPTSSITV
CCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHEECCCCCEEC
PGDTITKDGEATQLITKGRHDPCVGIRAVPIAEAMLAIVLLDHLLRHRGQNFGVTTETPK
CCCCCCCCCCHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
I
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8021209 [H]