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The map label for this gene is cvrA [H]

Identifier: 218708888

GI number: 218708888

Start: 912447

End: 914261

Strand: Direct

Name: cvrA [H]

Synonym: VS_0888

Alternate gene names: 218708888

Gene position: 912447-914261 (Clockwise)

Preceding gene: 218708887

Following gene: 218708891

Centisome position: 27.66

GC content: 47.0

Gene sequence:

>1815_bases
ATGGATTTGTCGATTACTTCTTCTTTGGCATTAATTGGACTGCTGTCTTTAACGTGTCAATTGTTAGGCTGGCGCTTCCG
TCTTCCTGCTATTCTTCCTCTTCTTATTGTCGGCCTACTTTTAGGTCCCGGTCTTAACATCCTTAATCCCGATGCCATTT
TTGGTGACGTGCTATTTCCGCTGATTTCATTAGGGGTCGCTATTATTCTGTTTGAAGGTGCATTGACCCTGAATTTCAAA
GAAATCAGAGGCCATGGTCGCATGGTGACGCACCTAGTGAGTATCGGCATGCTGATTACTTGGGCGTGCATCGTGGTTGG
TGCTTATTACTTTGTGGACTTCAGTTGGCCATTAGCCGCGCTGTTTGCTGCCTTAGTGGTGGTGACGGGACCTACAGTTA
TTGTTCCCATGCTGCGCAGCATTCAACCTAAATCTTCCTTAGGCAGTATCTTGCGCTGGGAAGGGATAGTGATTGATCCG
ATTGGCGCCCTGTTTGCTGTTCTTGTTTACGAATACATTGTCTCTTCAGCCGATCCTACAAGCCATGTACTGTCGGCCTT
GGGGCTGACTCTAGCCATCGGTTTAGGCTTAGGGATCATCGGTGGCTATTTGATTGCCAAGATGCTGCAAGGGCATTGGG
TTCCGCACTATTTGCGTAACGTCGCAGTCTTGACGTTGATGTTGGCGGCATTCTCTTTTTCTAATGATCTGAGTGAAGAG
TCTGGCCTATTAACCGTGACCATCATGGGCATCTGGCTCGCCAACGTGAAAGGCTTGGATCTTGAAGACATTATTGAGTT
CAAAGAGACCTTAACCGTGTTACTCATTTCTGCGTTGTTTATTCTGTTAGCTAGCAGGCTTGATTCAGGGACTTTTCTCT
CAATAGGTTGGGGCGGAATTGGCTTATTAGCGGTCGTCATGCTGGTGGCTCGTCCTCTGAGTGTGTGGATCAGCGGGATC
GGCACGGATCTTACCTCAGCAGATAAATGGTTTTTGAGCTGGATGGCGCCTCGCGGGATCGTTGCTGCCGCAGTTTCTTC
TCTGTTTGCTATCAAACTTCAAGAGAAGCAATTGATTGAAGGGGCTGATTTACTGGTTCCCATGGTGTTCTTGGTCATCA
TAGGCACGGTTGTGATTCAGAGCCTAACCGCAAGTTGGTGGGCGAGAAGGTTAGGTGTGACGCAAGAGAAAGCGCAAGGG
GTTATCTTCTTTGGCGCGACTCATTTTGCAAGACAGTTTGCCAAGGTGCTGGCAACACACAATATCAACAGTGTGCTTGC
CGATACCAACTGGGAAAGCATTCGTTTGGCGCGTATGGATAACCTGAATGTCTATTTTGGTAACCCAGCCTCAAGCCACG
CGGAAAATAATCTGGAATTGGACGGGATAGGGCGCGCGATGATCGTCTCGCCTTATCGTCAAACCAATCCATTAGTCAGT
ATGCATTATCAAGATGAGTTTGGTGAAAATAAGGTGTTTGAGCTTGAATCGACAGAAACTAAACACGAAAGGCATTCAGT
GAGCCGAGATGGTAACAGAAGCCTGTTTTCGGAAGGAATTACCTATTCCAAGCTTAACTCCTTGATGGCTCAAGGCTGCC
AAATAAAGAGTACAGGTTTGACCGAAGCGTTTGACCTTAATGAGTTTAACGCCCTGTATCCTAAAGCAATTCCACTCGGT
GTGATTACTGGCGGTGATTTCCGTTTAGTGACACAAGGTTCTAATTTGGAAAAACTCATATCAACGGAGTGTGCGATCAT
TAGTTTATTGCCGCCTTCGGATCCAACGGAAAGAACTGATGCTCCAGATAAGTAG

Upstream 100 bases:

>100_bases
AGCACGAAAAAGAGAGCCTATAGTTTAATGACATAGGCTTTCTTGTTTCAGCAAATAGGTTTGTATCACAAGGTGTGGTG
CAAACCTTTTAGGGGCACAA

Downstream 100 bases:

>100_bases
TGAGTGCTCTGTATTTAAAGCGAGTCACTTTGTATCAAAAACGAATAGCTCAGTATCAAAAAAGCCGCAACGTTTTAACG
CTGCGGCTTTTTAATTCTGT

Product: putative sodium/hydrogen exchanger family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 604; Mature: 604

Protein sequence:

>604_residues
MDLSITSSLALIGLLSLTCQLLGWRFRLPAILPLLIVGLLLGPGLNILNPDAIFGDVLFPLISLGVAIILFEGALTLNFK
EIRGHGRMVTHLVSIGMLITWACIVVGAYYFVDFSWPLAALFAALVVVTGPTVIVPMLRSIQPKSSLGSILRWEGIVIDP
IGALFAVLVYEYIVSSADPTSHVLSALGLTLAIGLGLGIIGGYLIAKMLQGHWVPHYLRNVAVLTLMLAAFSFSNDLSEE
SGLLTVTIMGIWLANVKGLDLEDIIEFKETLTVLLISALFILLASRLDSGTFLSIGWGGIGLLAVVMLVARPLSVWISGI
GTDLTSADKWFLSWMAPRGIVAAAVSSLFAIKLQEKQLIEGADLLVPMVFLVIIGTVVIQSLTASWWARRLGVTQEKAQG
VIFFGATHFARQFAKVLATHNINSVLADTNWESIRLARMDNLNVYFGNPASSHAENNLELDGIGRAMIVSPYRQTNPLVS
MHYQDEFGENKVFELESTETKHERHSVSRDGNRSLFSEGITYSKLNSLMAQGCQIKSTGLTEAFDLNEFNALYPKAIPLG
VITGGDFRLVTQGSNLEKLISTECAIISLLPPSDPTERTDAPDK

Sequences:

>Translated_604_residues
MDLSITSSLALIGLLSLTCQLLGWRFRLPAILPLLIVGLLLGPGLNILNPDAIFGDVLFPLISLGVAIILFEGALTLNFK
EIRGHGRMVTHLVSIGMLITWACIVVGAYYFVDFSWPLAALFAALVVVTGPTVIVPMLRSIQPKSSLGSILRWEGIVIDP
IGALFAVLVYEYIVSSADPTSHVLSALGLTLAIGLGLGIIGGYLIAKMLQGHWVPHYLRNVAVLTLMLAAFSFSNDLSEE
SGLLTVTIMGIWLANVKGLDLEDIIEFKETLTVLLISALFILLASRLDSGTFLSIGWGGIGLLAVVMLVARPLSVWISGI
GTDLTSADKWFLSWMAPRGIVAAAVSSLFAIKLQEKQLIEGADLLVPMVFLVIIGTVVIQSLTASWWARRLGVTQEKAQG
VIFFGATHFARQFAKVLATHNINSVLADTNWESIRLARMDNLNVYFGNPASSHAENNLELDGIGRAMIVSPYRQTNPLVS
MHYQDEFGENKVFELESTETKHERHSVSRDGNRSLFSEGITYSKLNSLMAQGCQIKSTGLTEAFDLNEFNALYPKAIPLG
VITGGDFRLVTQGSNLEKLISTECAIISLLPPSDPTERTDAPDK
>Mature_604_residues
MDLSITSSLALIGLLSLTCQLLGWRFRLPAILPLLIVGLLLGPGLNILNPDAIFGDVLFPLISLGVAIILFEGALTLNFK
EIRGHGRMVTHLVSIGMLITWACIVVGAYYFVDFSWPLAALFAALVVVTGPTVIVPMLRSIQPKSSLGSILRWEGIVIDP
IGALFAVLVYEYIVSSADPTSHVLSALGLTLAIGLGLGIIGGYLIAKMLQGHWVPHYLRNVAVLTLMLAAFSFSNDLSEE
SGLLTVTIMGIWLANVKGLDLEDIIEFKETLTVLLISALFILLASRLDSGTFLSIGWGGIGLLAVVMLVARPLSVWISGI
GTDLTSADKWFLSWMAPRGIVAAAVSSLFAIKLQEKQLIEGADLLVPMVFLVIIGTVVIQSLTASWWARRLGVTQEKAQG
VIFFGATHFARQFAKVLATHNINSVLADTNWESIRLARMDNLNVYFGNPASSHAENNLELDGIGRAMIVSPYRQTNPLVS
MHYQDEFGENKVFELESTETKHERHSVSRDGNRSLFSEGITYSKLNSLMAQGCQIKSTGLTEAFDLNEFNALYPKAIPLG
VITGGDFRLVTQGSNLEKLISTECAIISLLPPSDPTERTDAPDK

Specific function: Participates in control of cell volume in low-osmolarity conditions [H]

COG id: COG0025

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK C-terminal domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR016169
- InterPro:   IPR006037
- InterPro:   IPR005170 [H]

Pfam domain/function: PF03471 CorC_HlyC; PF00999 Na_H_Exchanger; PF02080 TrkA_C [H]

EC number: NA

Molecular weight: Translated: 65519; Mature: 65519

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLSITSSLALIGLLSLTCQLLGWRFRLPAILPLLIVGLLLGPGLNILNPDAIFGDVLFP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
LISLGVAIILFEGALTLNFKEIRGHGRMVTHLVSIGMLITWACIVVGAYYFVDFSWPLAA
HHHHHHHHHHCCCCCEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
LFAALVVVTGPTVIVPMLRSIQPKSSLGSILRWEGIVIDPIGALFAVLVYEYIVSSADPT
HHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHCCCEEECCHHHHHHHHHHHHHHCCCCHH
SHVLSALGLTLAIGLGLGIIGGYLIAKMLQGHWVPHYLRNVAVLTLMLAAFSFSNDLSEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
SGLLTVTIMGIWLANVKGLDLEDIIEFKETLTVLLISALFILLASRLDSGTFLSIGWGGI
CCEEEEEEEHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHH
GLLAVVMLVARPLSVWISGIGTDLTSADKWFLSWMAPRGIVAAAVSSLFAIKLQEKQLIE
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHC
GADLLVPMVFLVIIGTVVIQSLTASWWARRLGVTQEKAQGVIFFGATHFARQFAKVLATH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCEEEEECHHHHHHHHHHHHHHC
NINSVLADTNWESIRLARMDNLNVYFGNPASSHAENNLELDGIGRAMIVSPYRQTNPLVS
CCHHHHCCCCCCCEEEEEECCCEEEECCCCCCCCCCCCEECCCCCEEEECCCHHCCCEEE
MHYQDEFGENKVFELESTETKHERHSVSRDGNRSLFSEGITYSKLNSLMAQGCQIKSTGL
EEECCCCCCCCEEEECCCHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHCCCEEECCCC
TEAFDLNEFNALYPKAIPLGVITGGDFRLVTQGSNLEKLISTECAIISLLPPSDPTERTD
CCEECCCCCCCCCCCCCCEEEEECCCEEEEECCCCHHHHHHCCCEEEEECCCCCCCCCCC
APDK
CCCC
>Mature Secondary Structure
MDLSITSSLALIGLLSLTCQLLGWRFRLPAILPLLIVGLLLGPGLNILNPDAIFGDVLFP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
LISLGVAIILFEGALTLNFKEIRGHGRMVTHLVSIGMLITWACIVVGAYYFVDFSWPLAA
HHHHHHHHHHCCCCCEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
LFAALVVVTGPTVIVPMLRSIQPKSSLGSILRWEGIVIDPIGALFAVLVYEYIVSSADPT
HHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHCCCEEECCHHHHHHHHHHHHHHCCCCHH
SHVLSALGLTLAIGLGLGIIGGYLIAKMLQGHWVPHYLRNVAVLTLMLAAFSFSNDLSEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
SGLLTVTIMGIWLANVKGLDLEDIIEFKETLTVLLISALFILLASRLDSGTFLSIGWGGI
CCEEEEEEEHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHH
GLLAVVMLVARPLSVWISGIGTDLTSADKWFLSWMAPRGIVAAAVSSLFAIKLQEKQLIE
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHC
GADLLVPMVFLVIIGTVVIQSLTASWWARRLGVTQEKAQGVIFFGATHFARQFAKVLATH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCEEEEECHHHHHHHHHHHHHHC
NINSVLADTNWESIRLARMDNLNVYFGNPASSHAENNLELDGIGRAMIVSPYRQTNPLVS
CCHHHHCCCCCCCEEEEEECCCEEEECCCCCCCCCCCCEECCCCCEEEECCCHHCCCEEE
MHYQDEFGENKVFELESTETKHERHSVSRDGNRSLFSEGITYSKLNSLMAQGCQIKSTGL
EEECCCCCCCCEEEECCCHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHCCCEEECCCC
TEAFDLNEFNALYPKAIPLGVITGGDFRLVTQGSNLEKLISTECAIISLLPPSDPTERTD
CCEECCCCCCCCCCCCCCEEEEECCCEEEEECCCCHHHHHHCCCEEEEECCCCCCCCCCC
APDK
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]