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The map label for this gene is yeiM [C]

Identifier: 218708887

GI number: 218708887

Start: 911062

End: 912261

Strand: Direct

Name: yeiM [C]

Synonym: VS_0887

Alternate gene names: 218708887

Gene position: 911062-912261 (Clockwise)

Preceding gene: 218708886

Following gene: 218708888

Centisome position: 27.61

GC content: 46.25

Gene sequence:

>1200_bases
ATGGCTTCCCTACTTGGAATTATCACTATTTTAGTAGCCGCTTGGTTACTATCTACGGACAGAAAAAATATCCCGCTAAG
AACTGTCTCTTTGGCTTTCTTACTGCAAATCTCATTCGCGCTATTGGTTCTTTATGTGCCAATGGGTAAAGAAGCGCTGA
ATGCAGCTACTGGTGCGGTGTCTAGCTTGATCAACTACGGTCAAGAGGGGATTAACTTCCTATTCGGTGGCCTAACGAAT
AACGGATTTGTTTTCGCTATTAACGTTCTCGGCATCATTATCTTTTTCTCTGCATTGATTTCAGGTTTGTATCACATCGG
CTTTATGCCAAAGGTGATCAACATAATCGGCGGTGCTTTGCAGAAGTTTCTAGGCACAGGTCGTGCGGAGTCACTATCTG
CAACGGCAAACATTTTTGTTGGCATGATCGAAGCGCCATTGGTGGTTAAGCCTTACCTAAAACATATGACGGACTCACAA
CTGTTTGCTGTGATGGTATGTGGTTTGGCTTCTGTTGCTGGCGGCACGCTAGTGGGTTATGCATCGCTGGGTGTTGACCT
AAACTATCTGATCGCTGCGGCATTTATGTCGGCACCAGCCGGTCTATTGATGGCTAAAATCTTAGTACCAGGCAGCCCAG
AGGATGTTCAAGAAAATATTGAGTCTGGTGTAGATATTCCACGAGCAACAAACGTAGTTGAGGCAATGGCAGATGGGGCT
ATGTCTGGACTTCGTATTGCCGTTGCGGTGGGTGCGACACTTCTAGCCTTTATCAGTGTGATTGCGATGCTGAATGGCTT
GTTAGGTATTGTTGGTGGCTGGTTTGGCGTAAACCTAAGCTTCGAACTTATCCTAGGTTATGTGTTCGCACCCGTTGCAT
GGCTGATCGGTGTACCGTGGTCTGAAGCTGTGGTTGCAGGTTCGCTGATCGGTAATAAGATTGTTGTGAACGAATTTGTA
GCTTTCATCCAGTTAATGGACGTAAAAGATGCACTGAGTGAGCACTCAAAAGCGATCGTTACTTTTGCACTATGTGGTTT
TGCTAACATCTCTACCATGGCGATTCTGATTGGTGGTTTGGGTAGCTTAGTTCCAGAGCGTCGCTCTTTCATCTCACAAT
ATGGCTTCAAAGCGATTTGTGCGGGTGTGCTTGCCAACTTAATGAGCGCTGCGATCGCTGGCGTGGTGCTTTCTCTGTAG

Upstream 100 bases:

>100_bases
TGATAATCCCAACATCACATTAACAACCGCACCTTGCCGCAAACGATTTCCTCTATACAATGCGTCGCCTTTCCTACCTA
CAACTTTTAGGTTGACGCAT

Downstream 100 bases:

>100_bases
CTAGATAATAAGTACAGAGTGGATGAGTCAGTCACTTTATTTCCCCTATAGTAAAGTGACTGATTAATCACACTAATATT
CGGTTAGCACGAAAAAGAGA

Product: nucleoside permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 398

Protein sequence:

>399_residues
MASLLGIITILVAAWLLSTDRKNIPLRTVSLAFLLQISFALLVLYVPMGKEALNAATGAVSSLINYGQEGINFLFGGLTN
NGFVFAINVLGIIIFFSALISGLYHIGFMPKVINIIGGALQKFLGTGRAESLSATANIFVGMIEAPLVVKPYLKHMTDSQ
LFAVMVCGLASVAGGTLVGYASLGVDLNYLIAAAFMSAPAGLLMAKILVPGSPEDVQENIESGVDIPRATNVVEAMADGA
MSGLRIAVAVGATLLAFISVIAMLNGLLGIVGGWFGVNLSFELILGYVFAPVAWLIGVPWSEAVVAGSLIGNKIVVNEFV
AFIQLMDVKDALSEHSKAIVTFALCGFANISTMAILIGGLGSLVPERRSFISQYGFKAICAGVLANLMSAAIAGVVLSL

Sequences:

>Translated_399_residues
MASLLGIITILVAAWLLSTDRKNIPLRTVSLAFLLQISFALLVLYVPMGKEALNAATGAVSSLINYGQEGINFLFGGLTN
NGFVFAINVLGIIIFFSALISGLYHIGFMPKVINIIGGALQKFLGTGRAESLSATANIFVGMIEAPLVVKPYLKHMTDSQ
LFAVMVCGLASVAGGTLVGYASLGVDLNYLIAAAFMSAPAGLLMAKILVPGSPEDVQENIESGVDIPRATNVVEAMADGA
MSGLRIAVAVGATLLAFISVIAMLNGLLGIVGGWFGVNLSFELILGYVFAPVAWLIGVPWSEAVVAGSLIGNKIVVNEFV
AFIQLMDVKDALSEHSKAIVTFALCGFANISTMAILIGGLGSLVPERRSFISQYGFKAICAGVLANLMSAAIAGVVLSL
>Mature_398_residues
ASLLGIITILVAAWLLSTDRKNIPLRTVSLAFLLQISFALLVLYVPMGKEALNAATGAVSSLINYGQEGINFLFGGLTNN
GFVFAINVLGIIIFFSALISGLYHIGFMPKVINIIGGALQKFLGTGRAESLSATANIFVGMIEAPLVVKPYLKHMTDSQL
FAVMVCGLASVAGGTLVGYASLGVDLNYLIAAAFMSAPAGLLMAKILVPGSPEDVQENIESGVDIPRATNVVEAMADGAM
SGLRIAVAVGATLLAFISVIAMLNGLLGIVGGWFGVNLSFELILGYVFAPVAWLIGVPWSEAVVAGSLIGNKIVVNEFVA
FIQLMDVKDALSEHSKAIVTFALCGFANISTMAILIGGLGSLVPERRSFISQYGFKAICAGVLANLMSAAIAGVVLSL

Specific function: Unknown

COG id: COG1972

COG function: function code F; Nucleoside permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family [H]

Homologues:

Organism=Homo sapiens, GI42542381, Length=415, Percent_Identity=36.6265060240964, Blast_Score=239, Evalue=3e-63,
Organism=Homo sapiens, GI227116277, Length=409, Percent_Identity=34.9633251833741, Blast_Score=233, Evalue=2e-61,
Organism=Homo sapiens, GI11545853, Length=360, Percent_Identity=37.2222222222222, Blast_Score=225, Evalue=4e-59,
Organism=Escherichia coli, GI1788488, Length=414, Percent_Identity=42.9951690821256, Blast_Score=287, Evalue=8e-79,
Organism=Escherichia coli, GI1788485, Length=413, Percent_Identity=41.4043583535109, Blast_Score=285, Evalue=3e-78,
Organism=Escherichia coli, GI1788737, Length=394, Percent_Identity=31.7258883248731, Blast_Score=207, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI17560276, Length=392, Percent_Identity=29.8469387755102, Blast_Score=197, Evalue=7e-51,
Organism=Caenorhabditis elegans, GI71991794, Length=395, Percent_Identity=31.3924050632911, Blast_Score=194, Evalue=9e-50,
Organism=Caenorhabditis elegans, GI25146537, Length=194, Percent_Identity=31.4432989690722, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI45552517, Length=405, Percent_Identity=33.0864197530864, Blast_Score=230, Evalue=2e-60,
Organism=Drosophila melanogaster, GI19921868, Length=405, Percent_Identity=33.0864197530864, Blast_Score=230, Evalue=2e-60,
Organism=Drosophila melanogaster, GI45552519, Length=405, Percent_Identity=33.0864197530864, Blast_Score=230, Evalue=2e-60,
Organism=Drosophila melanogaster, GI281360430, Length=398, Percent_Identity=32.9145728643216, Blast_Score=219, Evalue=2e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008276
- InterPro:   IPR018270
- InterPro:   IPR011642
- InterPro:   IPR011657
- InterPro:   IPR002668 [H]

Pfam domain/function: PF07670 Gate; PF07662 Nucleos_tra2_C; PF01773 Nucleos_tra2_N [H]

EC number: NA

Molecular weight: Translated: 41524; Mature: 41393

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASLLGIITILVAAWLLSTDRKNIPLRTVSLAFLLQISFALLVLYVPMGKEALNAATGAV
CHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
SSLINYGQEGINFLFGGLTNNGFVFAINVLGIIIFFSALISGLYHIGFMPKVINIIGGAL
HHHHHHCHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QKFLGTGRAESLSATANIFVGMIEAPLVVKPYLKHMTDSQLFAVMVCGLASVAGGTLVGY
HHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHEEH
ASLGVDLNYLIAAAFMSAPAGLLMAKILVPGSPEDVQENIESGVDIPRATNVVEAMADGA
HHHCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHH
MSGLRIAVAVGATLLAFISVIAMLNGLLGIVGGWFGVNLSFELILGYVFAPVAWLIGVPW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCC
SEAVVAGSLIGNKIVVNEFVAFIQLMDVKDALSEHSKAIVTFALCGFANISTMAILIGGL
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GSLVPERRSFISQYGFKAICAGVLANLMSAAIAGVVLSL
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ASLLGIITILVAAWLLSTDRKNIPLRTVSLAFLLQISFALLVLYVPMGKEALNAATGAV
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
SSLINYGQEGINFLFGGLTNNGFVFAINVLGIIIFFSALISGLYHIGFMPKVINIIGGAL
HHHHHHCHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QKFLGTGRAESLSATANIFVGMIEAPLVVKPYLKHMTDSQLFAVMVCGLASVAGGTLVGY
HHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHEEH
ASLGVDLNYLIAAAFMSAPAGLLMAKILVPGSPEDVQENIESGVDIPRATNVVEAMADGA
HHHCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHH
MSGLRIAVAVGATLLAFISVIAMLNGLLGIVGGWFGVNLSFELILGYVFAPVAWLIGVPW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCC
SEAVVAGSLIGNKIVVNEFVAFIQLMDVKDALSEHSKAIVTFALCGFANISTMAILIGGL
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GSLVPERRSFISQYGFKAICAGVLANLMSAAIAGVVLSL
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]