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The map label for this gene is ttdR [H]

Identifier: 218708886

GI number: 218708886

Start: 909912

End: 910856

Strand: Direct

Name: ttdR [H]

Synonym: VS_0886

Alternate gene names: 218708886

Gene position: 909912-910856 (Clockwise)

Preceding gene: 218708885

Following gene: 218708887

Centisome position: 27.58

GC content: 46.46

Gene sequence:

>945_bases
GTGCTAACAGATAGAGCCGCACAGATGGTGATATTCCATGCGTTAATCAAGCATGAAGGCTTTACCAGTGCAGCAAAAAG
TTTGAATGTGTCGGTGTCTCACATCAGTAAGCAAGTTGCTTTGCTCGAGGATTCGATAGGTATCAAGCTGGTGCAAAGAA
CCACACGCAGCCTGACACTAACTGAAGCAGGGGAAGTGTTCTATCAGCATTGTGAGCAGCTGTTCAATACGGTGAAAGCG
GCTCAAATGGATATGGATAGCCAGCGTGACGACATTTCTGGAATATTCCGCATAGGCTTGTCTCAGTCATTTGGCACACT
GCATATCATTCCAGCGATTGATCAGCTCAGACAGCTCTATCCGCAGCTGAGAATTGAAGTGCATTTGTTCGATTACAAAG
TGGATATGATTGAGGAGCGCTTGGATCTTTGGATCACCAATAATGAAGACCTGCCAGAAGGTTATATTGCGCAGCGTTTA
GCCGACAGCCAATTTGTGGTAGCCGCATCACCGGATTATCTGATTAAAGCTGGTACTCCTCATGTGCCATCTGATCTGAT
TGACCATAACTGTCTTATCTATCGCAGCCGTGAACGAGACTACACGTCATGGGCGTTTGATAACGGGCAAGAAAACCTCA
GTGTCAAAGTGGCGGGCGATTACTCGGTGGATTTGGCTGAAGCGGTACGAGACGCGGCAGTATCGGGATGGGGTGTTGCT
TATTTGGCGACTTATTTAGTCAAAGAGGAGTTTAGAACAGGCAAGTTAATCCAAGTATTACCAGAATGGAGAGCCAGTCA
GTTGATGCCATTCTATGCCGTCTATCCGAGTCGAAAGAACATGCCAAAGAAGCTTTCAGCAGTGATTGAGTTCATCAAAC
AGCATGTTGGTTCGCCGACGTATTGGGACAAAAACCTCAAAACTTGCGTTGAGCTGCATCGTTAA

Upstream 100 bases:

>100_bases
TCGCTTTGAATAGCATTTGGCCTACCATAGGCAGAACGAACTAAAGGACTCTTCGGAGTCCTTTTTCTTTTATATTTCAG
AGATTTTTAAAGGTGGCCTT

Downstream 100 bases:

>100_bases
TTGTTTCCTAATTCATAAATATAATTTCCATATGGAAAAAGTATGCTTTTTGAACAAGTTAATCCATTAAAATTCAATGC
TTTAATCTAACCTTGGGCAA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MLTDRAAQMVIFHALIKHEGFTSAAKSLNVSVSHISKQVALLEDSIGIKLVQRTTRSLTLTEAGEVFYQHCEQLFNTVKA
AQMDMDSQRDDISGIFRIGLSQSFGTLHIIPAIDQLRQLYPQLRIEVHLFDYKVDMIEERLDLWITNNEDLPEGYIAQRL
ADSQFVVAASPDYLIKAGTPHVPSDLIDHNCLIYRSRERDYTSWAFDNGQENLSVKVAGDYSVDLAEAVRDAAVSGWGVA
YLATYLVKEEFRTGKLIQVLPEWRASQLMPFYAVYPSRKNMPKKLSAVIEFIKQHVGSPTYWDKNLKTCVELHR

Sequences:

>Translated_314_residues
MLTDRAAQMVIFHALIKHEGFTSAAKSLNVSVSHISKQVALLEDSIGIKLVQRTTRSLTLTEAGEVFYQHCEQLFNTVKA
AQMDMDSQRDDISGIFRIGLSQSFGTLHIIPAIDQLRQLYPQLRIEVHLFDYKVDMIEERLDLWITNNEDLPEGYIAQRL
ADSQFVVAASPDYLIKAGTPHVPSDLIDHNCLIYRSRERDYTSWAFDNGQENLSVKVAGDYSVDLAEAVRDAAVSGWGVA
YLATYLVKEEFRTGKLIQVLPEWRASQLMPFYAVYPSRKNMPKKLSAVIEFIKQHVGSPTYWDKNLKTCVELHR
>Mature_314_residues
MLTDRAAQMVIFHALIKHEGFTSAAKSLNVSVSHISKQVALLEDSIGIKLVQRTTRSLTLTEAGEVFYQHCEQLFNTVKA
AQMDMDSQRDDISGIFRIGLSQSFGTLHIIPAIDQLRQLYPQLRIEVHLFDYKVDMIEERLDLWITNNEDLPEGYIAQRL
ADSQFVVAASPDYLIKAGTPHVPSDLIDHNCLIYRSRERDYTSWAFDNGQENLSVKVAGDYSVDLAEAVRDAAVSGWGVA
YLATYLVKEEFRTGKLIQVLPEWRASQLMPFYAVYPSRKNMPKKLSAVIEFIKQHVGSPTYWDKNLKTCVELHR

Specific function: Positive regulator required for L-tartrate-dependent anaerobic growth on glycerol. Induces expression of the ttdA-ttdB- ygjE operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789440, Length=289, Percent_Identity=33.2179930795848, Blast_Score=175, Evalue=4e-45,
Organism=Escherichia coli, GI87081978, Length=285, Percent_Identity=31.9298245614035, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1786401, Length=291, Percent_Identity=27.8350515463918, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI1787128, Length=283, Percent_Identity=27.9151943462898, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI145693193, Length=294, Percent_Identity=28.9115646258503, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1789639, Length=286, Percent_Identity=29.3706293706294, Blast_Score=124, Evalue=9e-30,
Organism=Escherichia coli, GI1787589, Length=296, Percent_Identity=26.6891891891892, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1789173, Length=247, Percent_Identity=25.9109311740891, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI1790783, Length=255, Percent_Identity=27.0588235294118, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1788706, Length=304, Percent_Identity=21.3815789473684, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1787601, Length=172, Percent_Identity=26.7441860465116, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI157672245, Length=138, Percent_Identity=28.2608695652174, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1790399, Length=307, Percent_Identity=25.0814332247557, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788297, Length=303, Percent_Identity=23.4323432343234, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786448, Length=275, Percent_Identity=24.3636363636364, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787879, Length=146, Percent_Identity=29.4520547945205, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35699; Mature: 35699

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTDRAAQMVIFHALIKHEGFTSAAKSLNVSVSHISKQVALLEDSIGIKLVQRTTRSLTL
CCCHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHEEEE
TEAGEVFYQHCEQLFNTVKAAQMDMDSQRDDISGIFRIGLSQSFGTLHIIPAIDQLRQLY
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHH
PQLRIEVHLFDYKVDMIEERLDLWITNNEDLPEGYIAQRLADSQFVVAASPDYLIKAGTP
HHHEEEEEEEECHHHHHHHHHHEEEECCCCCCHHHHHHHHCCCCEEEEECCCEEEECCCC
HVPSDLIDHNCLIYRSRERDYTSWAFDNGQENLSVKVAGDYSVDLAEAVRDAAVSGWGVA
CCCHHHHCCCEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCHHH
YLATYLVKEEFRTGKLIQVLPEWRASQLMPFYAVYPSRKNMPKKLSAVIEFIKQHVGSPT
HHHHHHHHHHHCCCCHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCC
YWDKNLKTCVELHR
CCCHHHHHHHHHCC
>Mature Secondary Structure
MLTDRAAQMVIFHALIKHEGFTSAAKSLNVSVSHISKQVALLEDSIGIKLVQRTTRSLTL
CCCHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHEEEE
TEAGEVFYQHCEQLFNTVKAAQMDMDSQRDDISGIFRIGLSQSFGTLHIIPAIDQLRQLY
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHH
PQLRIEVHLFDYKVDMIEERLDLWITNNEDLPEGYIAQRLADSQFVVAASPDYLIKAGTP
HHHEEEEEEEECHHHHHHHHHHEEEECCCCCCHHHHHHHHCCCCEEEEECCCEEEECCCC
HVPSDLIDHNCLIYRSRERDYTSWAFDNGQENLSVKVAGDYSVDLAEAVRDAAVSGWGVA
CCCHHHHCCCEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCHHH
YLATYLVKEEFRTGKLIQVLPEWRASQLMPFYAVYPSRKNMPKKLSAVIEFIKQHVGSPT
HHHHHHHHHHHCCCCHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCC
YWDKNLKTCVELHR
CCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]