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The map label for this gene is nhaR [H]

Identifier: 218708565

GI number: 218708565

Start: 551096

End: 551986

Strand: Direct

Name: nhaR [H]

Synonym: VS_0531

Alternate gene names: 218708565

Gene position: 551096-551986 (Clockwise)

Preceding gene: 218708563

Following gene: 218708566

Centisome position: 16.7

GC content: 43.55

Gene sequence:

>891_bases
ATGTCGCATCTCAACTATAACCACCTTTATTACTTCTGGATGGTTTGCAAGCAAGGCTCTGTTACTAAAGCTGCAGAAGC
CTTATTCCTAACACCACAAACGGTAACAGGTCAGATAAAAGCCTTAGAAGAGCGTATGGATGGTAAGTTAACCAAGCGTA
ATGGTCGCAGTGTTGAGCCGACAGAGCTTGGGCAGTTGGTCTTTAAATATGCCGATCGTATGTTTGGCCTGAGTTACGAG
ATGCTGGATATCGTGAATTACAGCCAGCACTCCAATATTCTGTTTGATGTTGGCGTCGCGGATGCACTGTCCAAAAGATT
AGTCAGCAAGATATTGATGTCGACAATCCCACCCGATAACAGCATTCATTTACGCTGCTTTGAATCGACTCATGAAATGC
TACTTGAACAACTTTCTCAGCATAAGCTCGATATGATTTTGTCAGACTGCCCGGTGGATTCTAGCCAAAGCCCAGGCCTG
TTTAGTAAAAAGTTGGGTGAGAGTGGTATGAGCTTTTTCAGTTCAGGTAATGTGGAAGGTGTTAACTTTCCTGCTGTATT
AGAACAAAAGAAACTGTTAATCCCAGGAAGTCGAACTTCGATGGGGCGTAAAGTACTGCAATGGTTTGATAGACAAGGAC
TTAAGCCTGATATTTTGGGTGAGTTTGATGACGCGGCATTGATGAAGGCTTTCGCTCGTTACCACCACGACGCTATTTTC
TTAGCGCCTACGCTATATATGTCAGAGGTTGAGGAAGATACGTCATTGCAATTGTTGGGGGGAATCGAGGAGTTAAAAGA
GGAGTACTACGTCATATTTGCTGAGAGGATGATCCAACATCCCGCAGTAAAAAATGTATGTGACGCAGATTTTAGCAAAT
TGTTCGAGTGA

Upstream 100 bases:

>100_bases
TAAGTAGTAATTGATAGTTATGTATAGTTTTTCCGAGTTTGTTGAGTGGAGGTGTCATATTTGATATAACAGGTTATCTT
CTCTTTTTTACGGCACATTT

Downstream 100 bases:

>100_bases
GCTTGTTTGTTAATGAATTGATATCGATTATCATGACTTCATAATCTGCCGGAAATACTGATAACCCGGACTTGGCGTAA
AGGTTGTATGGAGCCAAACT

Product: transcriptional activator NhaR

Products: NA

Alternate protein names: Na(+)/H(+) antiporter regulatory protein [H]

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MSHLNYNHLYYFWMVCKQGSVTKAAEALFLTPQTVTGQIKALEERMDGKLTKRNGRSVEPTELGQLVFKYADRMFGLSYE
MLDIVNYSQHSNILFDVGVADALSKRLVSKILMSTIPPDNSIHLRCFESTHEMLLEQLSQHKLDMILSDCPVDSSQSPGL
FSKKLGESGMSFFSSGNVEGVNFPAVLEQKKLLIPGSRTSMGRKVLQWFDRQGLKPDILGEFDDAALMKAFARYHHDAIF
LAPTLYMSEVEEDTSLQLLGGIEELKEEYYVIFAERMIQHPAVKNVCDADFSKLFE

Sequences:

>Translated_296_residues
MSHLNYNHLYYFWMVCKQGSVTKAAEALFLTPQTVTGQIKALEERMDGKLTKRNGRSVEPTELGQLVFKYADRMFGLSYE
MLDIVNYSQHSNILFDVGVADALSKRLVSKILMSTIPPDNSIHLRCFESTHEMLLEQLSQHKLDMILSDCPVDSSQSPGL
FSKKLGESGMSFFSSGNVEGVNFPAVLEQKKLLIPGSRTSMGRKVLQWFDRQGLKPDILGEFDDAALMKAFARYHHDAIF
LAPTLYMSEVEEDTSLQLLGGIEELKEEYYVIFAERMIQHPAVKNVCDADFSKLFE
>Mature_295_residues
SHLNYNHLYYFWMVCKQGSVTKAAEALFLTPQTVTGQIKALEERMDGKLTKRNGRSVEPTELGQLVFKYADRMFGLSYEM
LDIVNYSQHSNILFDVGVADALSKRLVSKILMSTIPPDNSIHLRCFESTHEMLLEQLSQHKLDMILSDCPVDSSQSPGLF
SKKLGESGMSFFSSGNVEGVNFPAVLEQKKLLIPGSRTSMGRKVLQWFDRQGLKPDILGEFDDAALMKAFARYHHDAIFL
APTLYMSEVEEDTSLQLLGGIEELKEEYYVIFAERMIQHPAVKNVCDADFSKLFE

Specific function: Plays a role in the positive regulation of nhaA (Probable) [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786202, Length=295, Percent_Identity=64.7457627118644, Blast_Score=408, Evalue=1e-115,
Organism=Escherichia coli, GI1788297, Length=233, Percent_Identity=25.3218884120172, Blast_Score=68, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33529; Mature: 33398

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHLNYNHLYYFWMVCKQGSVTKAAEALFLTPQTVTGQIKALEERMDGKLTKRNGRSVEP
CCCCCCCCEEEEEEEECCCCHHHHHHHHEECCCHHHHHHHHHHHHHCCCEECCCCCCCCH
TELGQLVFKYADRMFGLSYEMLDIVNYSQHSNILFDVGVADALSKRLVSKILMSTIPPDN
HHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCC
SIHLRCFESTHEMLLEQLSQHKLDMILSDCPVDSSQSPGLFSKKLGESGMSFFSSGNVEG
CEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCC
VNFPAVLEQKKLLIPGSRTSMGRKVLQWFDRQGLKPDILGEFDDAALMKAFARYHHDAIF
CCCHHHHCCCEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCEEE
LAPTLYMSEVEEDTSLQLLGGIEELKEEYYVIFAERMIQHPAVKNVCDADFSKLFE
EHHHHHHHHHCCCCHHHHHHCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SHLNYNHLYYFWMVCKQGSVTKAAEALFLTPQTVTGQIKALEERMDGKLTKRNGRSVEP
CCCCCCCEEEEEEEECCCCHHHHHHHHEECCCHHHHHHHHHHHHHCCCEECCCCCCCCH
TELGQLVFKYADRMFGLSYEMLDIVNYSQHSNILFDVGVADALSKRLVSKILMSTIPPDN
HHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCC
SIHLRCFESTHEMLLEQLSQHKLDMILSDCPVDSSQSPGLFSKKLGESGMSFFSSGNVEG
CEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCC
VNFPAVLEQKKLLIPGSRTSMGRKVLQWFDRQGLKPDILGEFDDAALMKAFARYHHDAIF
CCCHHHHCCCEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCEEE
LAPTLYMSEVEEDTSLQLLGGIEELKEEYYVIFAERMIQHPAVKNVCDADFSKLFE
EHHHHHHHHHCCCCHHHHHHCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8231807; 9457888; 10952301 [H]