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The map label for this gene is arcB [H]

Identifier: 218708513

GI number: 218708513

Start: 500951

End: 503338

Strand: Direct

Name: arcB [H]

Synonym: VS_0477

Alternate gene names: 218708513

Gene position: 500951-503338 (Clockwise)

Preceding gene: 218708512

Following gene: 218708514

Centisome position: 15.18

GC content: 45.27

Gene sequence:

>2388_bases
ATGAAACCCATGAAAAATCTTGCCCAGTATTACGTGGATCTGCTCGTAAAATTGGGGATTGTCCGCTTTTCTATCTTACT
CGCCCTAGCGCTTGTTGCCCTTGCTGTTGTTGTACAAGTCGGTATCACCCTCGCACTCAAAGGTAATGTTGATGATATCG
ACATTGTCCGTTCGGTTTTCTTCGGTTTAGTGATCACACCTTGGGCGGTCTATTTTCTCTCAGTCGTGGTCGATCAACTG
GAAGAGTCTCGCCAAAGGTTGGCTAAATTGGTCTCTAAGCTGGGTGACATGCGAGAGCGAGATCAAGAACTCAACAATAA
ACTGCAACTCAATATCGAAAAGCTCAACCAAGAAATTGAAGATCGTGAAAAAGCCGAAGAAGCGCGTGCAGAAGCAATGC
ATGATCTTGAGAACGAAGTGTTTCAGCGTGAGCGAACTCAGCTTGAATTAGCAGAACGTACGGCGCTGTTGCGTTCGTTT
ATCGATGCCTCGCCTGACCTCATTTATTATCGCAATGAAGATGGTGTGTTTTCAGGTTGCAACCGAGCGGTTGAAGAACT
CACGGGCAAAACAGAAAAAGAGCTAGTTGGTTTGACGCCTTGGGATGTCTACAGCAAAGAGGTAGCCCAGCAAGTTGTTG
AAACCGATAAGAAAGTCTTTGCTGACAACCAAGCTTTGACCTATGACCAATGGCTTGAATACCCCGATGGACGTAAGAGT
TACTTCGAGCTGCGTAAGGTGCCTTTCTACAGTAAAGATGGTCGCCACCTTGGCTTGGTTGGTTTTGGTCGTGATATTAC
CGAGCGTAAAGAGCACCAAGAATCACTAGAGAAAGCCAGTCGCGATAAGACCACCTTTATCTCAACCATTAGCCACGAGC
TAAGAACACCGCTCAATGGCATCATCGGCTTGAGCCGCATGTTATTGGATAGCCAGCTGACGACCGAGCAGCGTAAGCAG
ATGCAAACCATCAAGGTGAGTGCGGTGACACTGGGTAATATCTTTAACGATATTATCGACATGGATAAGTTCGACCGCCG
TAAGCTTGAGCTATTCCCAACCCCTATCAATTTTGAAGATTTCGTTGTTGAGATCGAAAGCATTTCTGCGTTAATGGCAG
AGCAGAAAGGGTTGAGGTTTGATCTAGAAAGATTGTCCGATCTCCCATCTGCAGTTGAGGTGGATGGTACTCGTCTTAGA
CAGGTATTGTGGAACCTTGTCAGCAACGCGATGAAGTTCACCAAAGATGGTGGTGTGGTGATGACAGTCAGCGCCGAAAT
TGATGGCGACTTTGCCAACATAATGATGGAAGTAGAAGACACCGGGATTGGTATCCCTGAAAGTGAAATCGAGAAGATCT
TCGCGATGTACTATCAGGTAAAATCGGGCACGGACAATTTGCACGCTGTCGGCACGGGCATTGGCCTCGCGGTCTCACAG
CAGCTGATCAATATGATGGATGGCCACATTGAAGTCACCAGTGAAGAGGGCTTTGGTAGCACCTTTACGGTTTCGATTCG
AGTTCCAGTTAATCACGATACTCAGGCACTGATCAAAACGCCAAGAAAGCAGTCGAATCTTAAGATCTTCATGGTCGAAG
ATATTGAACTCAATATCACAGTGGCTCGCTCTCTACTTGAAAGTCTGGGTCATGAGGTGACAGTGGTAATGACGGGTAAA
GAGGCTCAGATTGCTTTCAACCCGGAAGACTATGACTTGGTACTGTTAGATATCCAACTGCCAGACATGACAGGTTTCGA
TATTGCTCAATACTACCGCGAGAAATACAGCCAACTACCGCCTTTGGTGGCATTAACCGCGAATGTATTAAACAATAAGC
AAGAGTATTTCCAGAAAGGCATGGATGAAGCGATCAGTAAACCACTGTCGGTTCGTGCAATCCAGGATGTCATCAGCGAG
TTGATTGAGGATGCCCCAGAGGTTATTGAGAAAGCCGAGGGCATTGATACAGTAAAGGATGTTGAAAAAGTAGCAGGTGT
TGAGAAAGTAACAGCGAGTAAGCCGGCTCTTTCAACGATTGATACCACTTTGCTTGATATTGATATGCTAGAGTCTTATG
TTGACATTGTCGGGTCGAAACCTGTTTTGGATAGTATCGTGATGTTTGAAGATATGATGCCGGAATATATGGAAATATTG
AATTCCAATATGGTTGCGAAAGATCAAGACAGTATCGTTTCTGAGGCACACAAGATTAAAGGTGCAGCAGGTTCCATTGG
CCTGAAACGCATACAGCAAGTTGCTCAGAAAGCTCAATCTCCAGATATGCCTGCGTGGTGGGAGAACATTTCAGATTGGG
TTGATGAAATAAATAACGAATACCAAAATGATATTGAAGTCTTAAAGAGTTGGTTAAATCAAAGGTAG

Upstream 100 bases:

>100_bases
CGATATTACCGCTAATCTCTTGCTGCGTGTGATGTAGCTAGCTTACCTACTTTCTTCAAACAAGGTAGAATGTTGCTAGT
CTTATCGCGTGGAGCGCTAA

Downstream 100 bases:

>100_bases
AAGAATGATGAAAAAATTAGCATTTGCCGCATGTGTAGTAGCATTAGCGGGTTGTTCTGCGCCACAAGTAGAATGGCAGC
AAGATAATCAAGTCGAAGTA

Product: aerobic respiration control sensor protein ArcB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 795; Mature: 795

Protein sequence:

>795_residues
MKPMKNLAQYYVDLLVKLGIVRFSILLALALVALAVVVQVGITLALKGNVDDIDIVRSVFFGLVITPWAVYFLSVVVDQL
EESRQRLAKLVSKLGDMRERDQELNNKLQLNIEKLNQEIEDREKAEEARAEAMHDLENEVFQRERTQLELAERTALLRSF
IDASPDLIYYRNEDGVFSGCNRAVEELTGKTEKELVGLTPWDVYSKEVAQQVVETDKKVFADNQALTYDQWLEYPDGRKS
YFELRKVPFYSKDGRHLGLVGFGRDITERKEHQESLEKASRDKTTFISTISHELRTPLNGIIGLSRMLLDSQLTTEQRKQ
MQTIKVSAVTLGNIFNDIIDMDKFDRRKLELFPTPINFEDFVVEIESISALMAEQKGLRFDLERLSDLPSAVEVDGTRLR
QVLWNLVSNAMKFTKDGGVVMTVSAEIDGDFANIMMEVEDTGIGIPESEIEKIFAMYYQVKSGTDNLHAVGTGIGLAVSQ
QLINMMDGHIEVTSEEGFGSTFTVSIRVPVNHDTQALIKTPRKQSNLKIFMVEDIELNITVARSLLESLGHEVTVVMTGK
EAQIAFNPEDYDLVLLDIQLPDMTGFDIAQYYREKYSQLPPLVALTANVLNNKQEYFQKGMDEAISKPLSVRAIQDVISE
LIEDAPEVIEKAEGIDTVKDVEKVAGVEKVTASKPALSTIDTTLLDIDMLESYVDIVGSKPVLDSIVMFEDMMPEYMEIL
NSNMVAKDQDSIVSEAHKIKGAAGSIGLKRIQQVAQKAQSPDMPAWWENISDWVDEINNEYQNDIEVLKSWLNQR

Sequences:

>Translated_795_residues
MKPMKNLAQYYVDLLVKLGIVRFSILLALALVALAVVVQVGITLALKGNVDDIDIVRSVFFGLVITPWAVYFLSVVVDQL
EESRQRLAKLVSKLGDMRERDQELNNKLQLNIEKLNQEIEDREKAEEARAEAMHDLENEVFQRERTQLELAERTALLRSF
IDASPDLIYYRNEDGVFSGCNRAVEELTGKTEKELVGLTPWDVYSKEVAQQVVETDKKVFADNQALTYDQWLEYPDGRKS
YFELRKVPFYSKDGRHLGLVGFGRDITERKEHQESLEKASRDKTTFISTISHELRTPLNGIIGLSRMLLDSQLTTEQRKQ
MQTIKVSAVTLGNIFNDIIDMDKFDRRKLELFPTPINFEDFVVEIESISALMAEQKGLRFDLERLSDLPSAVEVDGTRLR
QVLWNLVSNAMKFTKDGGVVMTVSAEIDGDFANIMMEVEDTGIGIPESEIEKIFAMYYQVKSGTDNLHAVGTGIGLAVSQ
QLINMMDGHIEVTSEEGFGSTFTVSIRVPVNHDTQALIKTPRKQSNLKIFMVEDIELNITVARSLLESLGHEVTVVMTGK
EAQIAFNPEDYDLVLLDIQLPDMTGFDIAQYYREKYSQLPPLVALTANVLNNKQEYFQKGMDEAISKPLSVRAIQDVISE
LIEDAPEVIEKAEGIDTVKDVEKVAGVEKVTASKPALSTIDTTLLDIDMLESYVDIVGSKPVLDSIVMFEDMMPEYMEIL
NSNMVAKDQDSIVSEAHKIKGAAGSIGLKRIQQVAQKAQSPDMPAWWENISDWVDEINNEYQNDIEVLKSWLNQR
>Mature_795_residues
MKPMKNLAQYYVDLLVKLGIVRFSILLALALVALAVVVQVGITLALKGNVDDIDIVRSVFFGLVITPWAVYFLSVVVDQL
EESRQRLAKLVSKLGDMRERDQELNNKLQLNIEKLNQEIEDREKAEEARAEAMHDLENEVFQRERTQLELAERTALLRSF
IDASPDLIYYRNEDGVFSGCNRAVEELTGKTEKELVGLTPWDVYSKEVAQQVVETDKKVFADNQALTYDQWLEYPDGRKS
YFELRKVPFYSKDGRHLGLVGFGRDITERKEHQESLEKASRDKTTFISTISHELRTPLNGIIGLSRMLLDSQLTTEQRKQ
MQTIKVSAVTLGNIFNDIIDMDKFDRRKLELFPTPINFEDFVVEIESISALMAEQKGLRFDLERLSDLPSAVEVDGTRLR
QVLWNLVSNAMKFTKDGGVVMTVSAEIDGDFANIMMEVEDTGIGIPESEIEKIFAMYYQVKSGTDNLHAVGTGIGLAVSQ
QLINMMDGHIEVTSEEGFGSTFTVSIRVPVNHDTQALIKTPRKQSNLKIFMVEDIELNITVARSLLESLGHEVTVVMTGK
EAQIAFNPEDYDLVLLDIQLPDMTGFDIAQYYREKYSQLPPLVALTANVLNNKQEYFQKGMDEAISKPLSVRAIQDVISE
LIEDAPEVIEKAEGIDTVKDVEKVAGVEKVTASKPALSTIDTTLLDIDMLESYVDIVGSKPVLDSIVMFEDMMPEYMEIL
NSNMVAKDQDSIVSEAHKIKGAAGSIGLKRIQQVAQKAQSPDMPAWWENISDWVDEINNEYQNDIEVLKSWLNQR

Specific function: Member of the two-component regulatory system ArcB/ArcA. Sensor-regulator protein for anaerobic repression of the arc modulon. Activates ArcA via a four-step phosphorelay. ArcB can also dephosphorylate ArcA by a reverse phosphorelay involving His- 717 and

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=796, Percent_Identity=57.4120603015075, Blast_Score=886, Evalue=0.0,
Organism=Escherichia coli, GI1788713, Length=523, Percent_Identity=27.7246653919694, Blast_Score=175, Evalue=1e-44,
Organism=Escherichia coli, GI1789149, Length=426, Percent_Identity=30.2816901408451, Blast_Score=172, Evalue=6e-44,
Organism=Escherichia coli, GI87081816, Length=543, Percent_Identity=25.7826887661142, Blast_Score=167, Evalue=3e-42,
Organism=Escherichia coli, GI145693157, Length=255, Percent_Identity=38.8235294117647, Blast_Score=159, Evalue=8e-40,
Organism=Escherichia coli, GI1788549, Length=367, Percent_Identity=27.2479564032698, Blast_Score=90, Evalue=5e-19,
Organism=Escherichia coli, GI1790436, Length=227, Percent_Identity=29.9559471365639, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788393, Length=248, Percent_Identity=24.5967741935484, Blast_Score=80, Evalue=7e-16,
Organism=Escherichia coli, GI1786600, Length=380, Percent_Identity=23.4210526315789, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1786912, Length=245, Percent_Identity=24.0816326530612, Blast_Score=74, Evalue=5e-14,
Organism=Escherichia coli, GI1790346, Length=221, Percent_Identity=26.6968325791855, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1786783, Length=236, Percent_Identity=24.1525423728814, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI87082128, Length=252, Percent_Identity=25.7936507936508, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=160, Percent_Identity=28.125, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR014409
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 89754; Mature: 89754

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: PS50894 HPT ; PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPMKNLAQYYVDLLVKLGIVRFSILLALALVALAVVVQVGITLALKGNVDDIDIVRSVF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHH
FGLVITPWAVYFLSVVVDQLEESRQRLAKLVSKLGDMRERDQELNNKLQLNIEKLNQEIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEHHHHHHHHH
DREKAEEARAEAMHDLENEVFQRERTQLELAERTALLRSFIDASPDLIYYRNEDGVFSGC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHH
NRAVEELTGKTEKELVGLTPWDVYSKEVAQQVVETDKKVFADNQALTYDQWLEYPDGRKS
HHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHCCCCCCHH
YFELRKVPFYSKDGRHLGLVGFGRDITERKEHQESLEKASRDKTTFISTISHELRTPLNG
HHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCHHHH
IIGLSRMLLDSQLTTEQRKQMQTIKVSAVTLGNIFNDIIDMDKFDRRKLELFPTPINFED
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCHHH
FVVEIESISALMAEQKGLRFDLERLSDLPSAVEVDGTRLRQVLWNLVSNAMKFTKDGGVV
HHHHHHHHHHHHHHHCCCEEEHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEE
MTVSAEIDGDFANIMMEVEDTGIGIPESEIEKIFAMYYQVKSGTDNLHAVGTGIGLAVSQ
EEEEECCCCCHHHHEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEHHCCHHHHHHH
QLINMMDGHIEVTSEEGFGSTFTVSIRVPVNHDTQALIKTPRKQSNLKIFMVEDIELNIT
HHHHHHCCCEEEECCCCCCCEEEEEEEEECCCCCHHHHHCCCCCCCEEEEEEECCEEHHH
VARSLLESLGHEVTVVMTGKEAQIAFNPEDYDLVLLDIQLPDMTGFDIAQYYREKYSQLP
HHHHHHHHCCCEEEEEEECCCEEEEECCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCC
PLVALTANVLNNKQEYFQKGMDEAISKPLSVRAIQDVISELIEDAPEVIEKAEGIDTVKD
CHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
VEKVAGVEKVTASKPALSTIDTTLLDIDMLESYVDIVGSKPVLDSIVMFEDMMPEYMEIL
HHHHHCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
NSNMVAKDQDSIVSEAHKIKGAAGSIGLKRIQQVAQKAQSPDMPAWWENISDWVDEINNE
CCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
YQNDIEVLKSWLNQR
HHHHHHHHHHHHCCC
>Mature Secondary Structure
MKPMKNLAQYYVDLLVKLGIVRFSILLALALVALAVVVQVGITLALKGNVDDIDIVRSVF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHH
FGLVITPWAVYFLSVVVDQLEESRQRLAKLVSKLGDMRERDQELNNKLQLNIEKLNQEIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEHHHHHHHHH
DREKAEEARAEAMHDLENEVFQRERTQLELAERTALLRSFIDASPDLIYYRNEDGVFSGC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHH
NRAVEELTGKTEKELVGLTPWDVYSKEVAQQVVETDKKVFADNQALTYDQWLEYPDGRKS
HHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHCCCCCCHH
YFELRKVPFYSKDGRHLGLVGFGRDITERKEHQESLEKASRDKTTFISTISHELRTPLNG
HHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCHHHH
IIGLSRMLLDSQLTTEQRKQMQTIKVSAVTLGNIFNDIIDMDKFDRRKLELFPTPINFED
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCHHH
FVVEIESISALMAEQKGLRFDLERLSDLPSAVEVDGTRLRQVLWNLVSNAMKFTKDGGVV
HHHHHHHHHHHHHHHCCCEEEHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEE
MTVSAEIDGDFANIMMEVEDTGIGIPESEIEKIFAMYYQVKSGTDNLHAVGTGIGLAVSQ
EEEEECCCCCHHHHEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEHHCCHHHHHHH
QLINMMDGHIEVTSEEGFGSTFTVSIRVPVNHDTQALIKTPRKQSNLKIFMVEDIELNIT
HHHHHHCCCEEEECCCCCCCEEEEEEEEECCCCCHHHHHCCCCCCCEEEEEEECCEEHHH
VARSLLESLGHEVTVVMTGKEAQIAFNPEDYDLVLLDIQLPDMTGFDIAQYYREKYSQLP
HHHHHHHHCCCEEEEEEECCCEEEEECCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCC
PLVALTANVLNNKQEYFQKGMDEAISKPLSVRAIQDVISELIEDAPEVIEKAEGIDTVKD
CHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
VEKVAGVEKVTASKPALSTIDTTLLDIDMLESYVDIVGSKPVLDSIVMFEDMMPEYMEIL
HHHHHCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
NSNMVAKDQDSIVSEAHKIKGAAGSIGLKRIQQVAQKAQSPDMPAWWENISDWVDEINNE
CCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
YQNDIEVLKSWLNQR
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]