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The map label for this gene is exeA [H]

Identifier: 218708445

GI number: 218708445

Start: 413468

End: 415138

Strand: Direct

Name: exeA [H]

Synonym: VS_0408

Alternate gene names: 218708445

Gene position: 413468-415138 (Clockwise)

Preceding gene: 218708443

Following gene: 218708446

Centisome position: 12.53

GC content: 45.6

Gene sequence:

>1671_bases
ATGTATAAGGAATATTTTGGCTTCGTTGAGATGCCATTTTCGATTGTACCAAATTCTCGCTATTTGTTTTTGAGTCAGCG
TCACCAAGAAGCTATACAAAACCTACAAGCCGGTTTAGGTGAGGGGGGGGGATTTGCGATGCTTACTGGTGAAGTAGGTA
CAGGAAAAACAACGGTCGCCAAAGCGATGTTGTCATCACTCGATAATCAGACTCAAGCTGGCCTTATACTCAACCCTACG
TTTTCCAATTCAGATTTACTTGAAGCTATCTGCGATGAGTTTGAGGTCGAATACCCTGAACAAGCGTCGTTAAAACAGCT
GAGTCAGGCAATTCATCACTTCCTGCTTGATAGCCATGCTGAAGGCATTCAAACCTTATTGGTGATCGATGAAGCCCAAC
ACCTCGCTGCCGATGTGTTGGAGCAGTTACGCCTTCTAACAAACTTGGAAACCGACAATCGTAAGCTGTTAAAAGTACTG
TTGGTCGGCCAGCCGGAATTACAACAGCACTTACAAACCACGCAGCTACGTCAGCTAGCACAGCGCATTACCGGTCGTTA
TCACTTACTGCCTCTTAATACCGAAGAAACGGGCAAGTACATCGCGTTTCGTTTGGAAACGGCGGGTGGCGAGCAGATGT
TGTTTTCGAACCGTTCTATCAAGCTGATCGCTCAATATACGCATGGTATTCCAAGGCTCATTAACTTGGTGTGTGACAAA
GCACTGCAGTTGGCTTTTCATGATGGAGAGCAGCTACCGAGCAATGAAACGGTTAACCGAGCATGTCAGCAGGTTATGTC
CTTTCAGGCTGATGTGTATCACGTCGAGAAACCTCGAACTTCTCGTGCTGCGACCAAGTTATTCCAATACGCAGGGATTG
CGACGTTAAGCGTTGGTCTTGCAATTGCGACCTTTAATTTCGCTCCAAGCTATATCAATGCTTGGTTGCCTACGGATGCT
TCAGATGAAGCGAAGACGGAAGTGTTAGCACACACTCAGCGTTCTTTGGTATCAGATGTTCCTAAGTTGGTAGCTGAGCC
AAAACCTGCCAAGTTTGAATTGCCACAACACATTCAACAACATTTGATGCAGGGGACCAATCGTTCTCTTGCTATCAAAG
ACTTGTATACGTTGTGGGGATATCAATCTTCACTGCGTGATGGATTGTGCTTAAGTGAGCCACAGAGTGTTTTTGTGTGT
GATCAGCAACAGGCCAATTTGGATACATTGTTAGAACTAGGCGTGCCTGTGGTGCTTAATCTCGACATAGACCAAAAACC
AGTGTTTGCTGTGCTGTATGGCGTGTCTAAGGATTCTGTCGAGTTGCTGGTTAATGAAAAGCTGTTGGTGATGCCGAAGC
AATCCTTAGAGCAAATCTGGCAAGGCGATTACGTCGCTATTTGGAAGCAGCCGCTGCGAGAGACACTCAAAGAAGGCTAT
CAAGGTGAAGCGGTTGCTTTGCTTGATCTACTGCTTTCTGAAGTATTAGGAGAGGTTGTTTCCGGTAGTGATGTATTTGA
TTATGAGTTAAAAATGAAAATCGAAGCATTTCAAACGTGGCAGGGTATGTCTGTTGATGGCATTGCAGGTAAGCTCACCT
TGGCAAGATTGCAGAGATTAGCTCAACTCGATTCGCCTAAGTTGATGTCACTAGAAGGGGGCGAAAGCTAA

Upstream 100 bases:

>100_bases
TATCGTATATTTGCAACTTATCACCTCGAAATGTTTTATCACTGCTGGACTTTACTGCGAGCAATGGTACTTTCCATTAA
TCGTAATTATAGGGCAGCAC

Downstream 100 bases:

>100_bases
TGTCACGTATTATGCACGAGCTTAAACAGTCTTCTAATAATAAACCTAGCTTTAAAGGTTACCAAAACCATCACGTGCCT
AGTTCTGCTAAAGGGATTAG

Product: putative general secretion pathway protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 556; Mature: 556

Protein sequence:

>556_residues
MYKEYFGFVEMPFSIVPNSRYLFLSQRHQEAIQNLQAGLGEGGGFAMLTGEVGTGKTTVAKAMLSSLDNQTQAGLILNPT
FSNSDLLEAICDEFEVEYPEQASLKQLSQAIHHFLLDSHAEGIQTLLVIDEAQHLAADVLEQLRLLTNLETDNRKLLKVL
LVGQPELQQHLQTTQLRQLAQRITGRYHLLPLNTEETGKYIAFRLETAGGEQMLFSNRSIKLIAQYTHGIPRLINLVCDK
ALQLAFHDGEQLPSNETVNRACQQVMSFQADVYHVEKPRTSRAATKLFQYAGIATLSVGLAIATFNFAPSYINAWLPTDA
SDEAKTEVLAHTQRSLVSDVPKLVAEPKPAKFELPQHIQQHLMQGTNRSLAIKDLYTLWGYQSSLRDGLCLSEPQSVFVC
DQQQANLDTLLELGVPVVLNLDIDQKPVFAVLYGVSKDSVELLVNEKLLVMPKQSLEQIWQGDYVAIWKQPLRETLKEGY
QGEAVALLDLLLSEVLGEVVSGSDVFDYELKMKIEAFQTWQGMSVDGIAGKLTLARLQRLAQLDSPKLMSLEGGES

Sequences:

>Translated_556_residues
MYKEYFGFVEMPFSIVPNSRYLFLSQRHQEAIQNLQAGLGEGGGFAMLTGEVGTGKTTVAKAMLSSLDNQTQAGLILNPT
FSNSDLLEAICDEFEVEYPEQASLKQLSQAIHHFLLDSHAEGIQTLLVIDEAQHLAADVLEQLRLLTNLETDNRKLLKVL
LVGQPELQQHLQTTQLRQLAQRITGRYHLLPLNTEETGKYIAFRLETAGGEQMLFSNRSIKLIAQYTHGIPRLINLVCDK
ALQLAFHDGEQLPSNETVNRACQQVMSFQADVYHVEKPRTSRAATKLFQYAGIATLSVGLAIATFNFAPSYINAWLPTDA
SDEAKTEVLAHTQRSLVSDVPKLVAEPKPAKFELPQHIQQHLMQGTNRSLAIKDLYTLWGYQSSLRDGLCLSEPQSVFVC
DQQQANLDTLLELGVPVVLNLDIDQKPVFAVLYGVSKDSVELLVNEKLLVMPKQSLEQIWQGDYVAIWKQPLRETLKEGY
QGEAVALLDLLLSEVLGEVVSGSDVFDYELKMKIEAFQTWQGMSVDGIAGKLTLARLQRLAQLDSPKLMSLEGGES
>Mature_556_residues
MYKEYFGFVEMPFSIVPNSRYLFLSQRHQEAIQNLQAGLGEGGGFAMLTGEVGTGKTTVAKAMLSSLDNQTQAGLILNPT
FSNSDLLEAICDEFEVEYPEQASLKQLSQAIHHFLLDSHAEGIQTLLVIDEAQHLAADVLEQLRLLTNLETDNRKLLKVL
LVGQPELQQHLQTTQLRQLAQRITGRYHLLPLNTEETGKYIAFRLETAGGEQMLFSNRSIKLIAQYTHGIPRLINLVCDK
ALQLAFHDGEQLPSNETVNRACQQVMSFQADVYHVEKPRTSRAATKLFQYAGIATLSVGLAIATFNFAPSYINAWLPTDA
SDEAKTEVLAHTQRSLVSDVPKLVAEPKPAKFELPQHIQQHLMQGTNRSLAIKDLYTLWGYQSSLRDGLCLSEPQSVFVC
DQQQANLDTLLELGVPVVLNLDIDQKPVFAVLYGVSKDSVELLVNEKLLVMPKQSLEQIWQGDYVAIWKQPLRETLKEGY
QGEAVALLDLLLSEVLGEVVSGSDVFDYELKMKIEAFQTWQGMSVDGIAGKLTLARLQRLAQLDSPKLMSLEGGES

Specific function: Involved in a general secretion pathway (GSP) for the export of proteins [H]

COG id: COG3267

COG function: function code U; Type II secretory pathway, component ExeA (predicted ATPase)

Gene ontology:

Cell location: Cytoplasm. Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exeA family [H]

Homologues:

Organism=Escherichia coli, GI1789720, Length=175, Percent_Identity=28, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR002477 [H]

Pfam domain/function: PF00004 AAA; PF01471 PG_binding_1 [H]

EC number: NA

Molecular weight: Translated: 61913; Mature: 61913

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKEYFGFVEMPFSIVPNSRYLFLSQRHQEAIQNLQAGLGEGGGFAMLTGEVGTGKTTVA
CCHHHCCHHCCCCEECCCCEEEEEEHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHH
KAMLSSLDNQTQAGLILNPTFSNSDLLEAICDEFEVEYPEQASLKQLSQAIHHFLLDSHA
HHHHHHCCCCCCCCEEECCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCH
EGIQTLLVIDEAQHLAADVLEQLRLLTNLETDNRKLLKVLLVGQPELQQHLQTTQLRQLA
HHHEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHH
QRITGRYHLLPLNTEETGKYIAFRLETAGGEQMLFSNRSIKLIAQYTHGIPRLINLVCDK
HHHCCCEEEEECCCCCCCCEEEEEEECCCCCEEEECCCCEEEEEHHHCCHHHHHHHHHHH
ALQLAFHDGEQLPSNETVNRACQQVMSFQADVYHVEKPRTSRAATKLFQYAGIATLSVGL
HHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHCHHHHHHHH
AIATFNFAPSYINAWLPTDASDEAKTEVLAHTQRSLVSDVPKLVAEPKPAKFELPQHIQQ
HHEEECCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
HLMQGTNRSLAIKDLYTLWGYQSSLRDGLCLSEPQSVFVCDQQQANLDTLLELGVPVVLN
HHHCCCCCCEEHHHHHHHHCCHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHCCCCEEEE
LDIDQKPVFAVLYGVSKDSVELLVNEKLLVMPKQSLEQIWQGDYVAIWKQPLRETLKEGY
ECCCCCCCEEEEECCCCCCHHHHCCCCEEECCHHHHHHHHCCCEEHHHHHHHHHHHHCCC
QGEAVALLDLLLSEVLGEVVSGSDVFDYELKMKIEAFQTWQGMSVDGIAGKLTLARLQRL
CCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEHHHCCCCCCCCCCHHHHHHHHHHHH
AQLDSPKLMSLEGGES
HHCCCCCEECCCCCCC
>Mature Secondary Structure
MYKEYFGFVEMPFSIVPNSRYLFLSQRHQEAIQNLQAGLGEGGGFAMLTGEVGTGKTTVA
CCHHHCCHHCCCCEECCCCEEEEEEHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHH
KAMLSSLDNQTQAGLILNPTFSNSDLLEAICDEFEVEYPEQASLKQLSQAIHHFLLDSHA
HHHHHHCCCCCCCCEEECCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCH
EGIQTLLVIDEAQHLAADVLEQLRLLTNLETDNRKLLKVLLVGQPELQQHLQTTQLRQLA
HHHEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHH
QRITGRYHLLPLNTEETGKYIAFRLETAGGEQMLFSNRSIKLIAQYTHGIPRLINLVCDK
HHHCCCEEEEECCCCCCCCEEEEEEECCCCCEEEECCCCEEEEEHHHCCHHHHHHHHHHH
ALQLAFHDGEQLPSNETVNRACQQVMSFQADVYHVEKPRTSRAATKLFQYAGIATLSVGL
HHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHCHHHHHHHH
AIATFNFAPSYINAWLPTDASDEAKTEVLAHTQRSLVSDVPKLVAEPKPAKFELPQHIQQ
HHEEECCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
HLMQGTNRSLAIKDLYTLWGYQSSLRDGLCLSEPQSVFVCDQQQANLDTLLELGVPVVLN
HHHCCCCCCEEHHHHHHHHCCHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHCCCCEEEE
LDIDQKPVFAVLYGVSKDSVELLVNEKLLVMPKQSLEQIWQGDYVAIWKQPLRETLKEGY
ECCCCCCCEEEEECCCCCCHHHHCCCCEEECCHHHHHHHHCCCEEHHHHHHHHHHHHCCC
QGEAVALLDLLLSEVLGEVVSGSDVFDYELKMKIEAFQTWQGMSVDGIAGKLTLARLQRL
CCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEHHHCCCCCCCCCCHHHHHHHHHHHH
AQLDSPKLMSLEGGES
HHCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7961440 [H]