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The map label for this gene is uppP

Identifier: 218708443

GI number: 218708443

Start: 411223

End: 412026

Strand: Direct

Name: uppP

Synonym: VS_0406

Alternate gene names: 218708443

Gene position: 411223-412026 (Clockwise)

Preceding gene: 218708442

Following gene: 218708445

Centisome position: 12.46

GC content: 45.52

Gene sequence:

>804_bases
ATGAGTTATTTTGAAGCGTTTATGTTGGCGTTGGTGCAAGGCTTTACTGAGTTTTTACCTATTTCCAGCTCTGCACACTT
AATCCTTCCTTCGGCTGTTTTAGGTTGGGAAGATCAAGGCTTGGCTTTTGATGTGGCGGTCCATGTCGGTACTTTGGCAG
CTGTCGTTATCTATTTTCGCAAAGAAGTGGTCTCTCTGTTGAGCGCATTTTTTGGTTCAGTGTTTAAAGGCGATCGCAGT
AAAGAAGCAAAGCTGGCGTGGATGATCATTCTCGCGACGATTCCTGCGTGTATCTTTGGTTTGTTGATGAAAGATATTGT
TGAGCTTTACTTGCGCAGTGCATGGGTGATAGCGACGACCACCATTATCTTTGGTCTGTTGCTATGGTGGGTGGATAAGA
ACTCAAGCCTGCGTGATGACGAATACCAAGCGGGTTGGAAAAAGGCGCTGTTTATTGGCCTTGCTCAAGCAATGGCGATC
ATCCCAGGTACGTCTCGTTCTGGCGCGACGATTACCGCAGCACTTTACCTTGGTTTCACACGTGAAGCGGCGGCTCGATT
CTCTTTCTTAATGTCTATCCCAATCATCACTCTGGCTGGTGGTTATTTGGGCTTGAAGTTAGTGACCAGTGGTGATCCAA
TCCATGTTGGTACTTTGCTAACGGGAATCGTGGTTTCTTTCATTAGTGCTTATATCTGTATTCACTTTTTCTTGAAGCTT
ATCTCACGCATGGGTATGACACCGTTCGTTATCTACCGCTTGATTCTAGGTTTTGGTCTGTTTGCGTTCTTGATGATGCA
GTAA

Upstream 100 bases:

>100_bases
CCGCAAGATGGAAGAACCGTCAGTGAAATATGGCAGAAGATGCAGCAATTAGATACGCTCTCTGTCGTTGATATAACACT
ATAATTTTTTAGGGTAAGTA

Downstream 100 bases:

>100_bases
AAAGCGCTTATGCAGCACCCTACAAGTTGAAACGAAAAACCCGCTTAATCGCGGGTTTTTTAATGTGTGTTTACTAGTGT
AATGAAGATTAACTATTAGA

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MSYFEAFMLALVQGFTEFLPISSSAHLILPSAVLGWEDQGLAFDVAVHVGTLAAVVIYFRKEVVSLLSAFFGSVFKGDRS
KEAKLAWMIILATIPACIFGLLMKDIVELYLRSAWVIATTTIIFGLLLWWVDKNSSLRDDEYQAGWKKALFIGLAQAMAI
IPGTSRSGATITAALYLGFTREAAARFSFLMSIPIITLAGGYLGLKLVTSGDPIHVGTLLTGIVVSFISAYICIHFFLKL
ISRMGMTPFVIYRLILGFGLFAFLMMQ

Sequences:

>Translated_267_residues
MSYFEAFMLALVQGFTEFLPISSSAHLILPSAVLGWEDQGLAFDVAVHVGTLAAVVIYFRKEVVSLLSAFFGSVFKGDRS
KEAKLAWMIILATIPACIFGLLMKDIVELYLRSAWVIATTTIIFGLLLWWVDKNSSLRDDEYQAGWKKALFIGLAQAMAI
IPGTSRSGATITAALYLGFTREAAARFSFLMSIPIITLAGGYLGLKLVTSGDPIHVGTLLTGIVVSFISAYICIHFFLKL
ISRMGMTPFVIYRLILGFGLFAFLMMQ
>Mature_266_residues
SYFEAFMLALVQGFTEFLPISSSAHLILPSAVLGWEDQGLAFDVAVHVGTLAAVVIYFRKEVVSLLSAFFGSVFKGDRSK
EAKLAWMIILATIPACIFGLLMKDIVELYLRSAWVIATTTIIFGLLLWWVDKNSSLRDDEYQAGWKKALFIGLAQAMAII
PGTSRSGATITAALYLGFTREAAARFSFLMSIPIITLAGGYLGLKLVTSGDPIHVGTLLTGIVVSFISAYICIHFFLKLI
SRMGMTPFVIYRLILGFGLFAFLMMQ

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=262, Percent_Identity=34.3511450381679, Blast_Score=135, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_VIBSL (B7VIW0)

Other databases:

- EMBL:   FM954972
- RefSeq:   YP_002416064.1
- ProteinModelPortal:   B7VIW0
- GeneID:   7160042
- GenomeReviews:   FM954972_GR
- KEGG:   vsp:VS_0406
- HOGENOM:   HBG391969
- OMA:   HSMYWFV
- ProtClustDB:   PRK00281
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824
- TIGRFAMs:   TIGR00753

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 29309; Mature: 29178

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1868dc98)-; HASH(0x185c00d4)-; HASH(0x193e7ce0)-; HASH(0x192727b0)-; HASH(0x1998efec)-; HASH(0x195e8f70)-; HASH(0x188dabec)-; HASH(0x19978028)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYFEAFMLALVQGFTEFLPISSSAHLILPSAVLGWEDQGLAFDVAVHVGTLAAVVIYFR
CCHHHHHHHHHHHHHHHHCCCCCCCCEEECHHHHCCCCCCCEEHHHHHHHHHHHHHHHHH
KEVVSLLSAFFGSVFKGDRSKEAKLAWMIILATIPACIFGLLMKDIVELYLRSAWVIATT
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TIIFGLLLWWVDKNSSLRDDEYQAGWKKALFIGLAQAMAIIPGTSRSGATITAALYLGFT
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHH
REAAARFSFLMSIPIITLAGGYLGLKLVTSGDPIHVGTLLTGIVVSFISAYICIHFFLKL
HHHHHHHHHHHHHHHHHHCCCHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ISRMGMTPFVIYRLILGFGLFAFLMMQ
HHHCCCCHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure 
SYFEAFMLALVQGFTEFLPISSSAHLILPSAVLGWEDQGLAFDVAVHVGTLAAVVIYFR
CHHHHHHHHHHHHHHHHCCCCCCCCEEECHHHHCCCCCCCEEHHHHHHHHHHHHHHHHH
KEVVSLLSAFFGSVFKGDRSKEAKLAWMIILATIPACIFGLLMKDIVELYLRSAWVIATT
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TIIFGLLLWWVDKNSSLRDDEYQAGWKKALFIGLAQAMAIIPGTSRSGATITAALYLGFT
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHH
REAAARFSFLMSIPIITLAGGYLGLKLVTSGDPIHVGTLLTGIVVSFISAYICIHFFLKL
HHHHHHHHHHHHHHHHHHCCCHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ISRMGMTPFVIYRLILGFGLFAFLMMQ
HHHCCCCHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA