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The map label for this gene is yafV [C]

Identifier: 218708387

GI number: 218708387

Start: 345391

End: 346203

Strand: Direct

Name: yafV [C]

Synonym: VS_0347

Alternate gene names: 218708387

Gene position: 345391-346203 (Clockwise)

Preceding gene: 218708386

Following gene: 218708388

Centisome position: 10.47

GC content: 46.0

Gene sequence:

>813_bases
ATGGATTGTGTTGGGTTGATTCAAATGACATCAGGCCCTCGCCCTGACTTGAACTTTGATTATCTTGCTCAAGAAGTAGC
AAAGTGCAAAGAGTTGGGGGCTAAGTGGGTTGTGTGCCCTGAAAACGCGTTAGTCTTTGGCAGTAAAGCCGACTATCACC
AGTATGCTGAGCCTCTAAATGATGGTCCACTGCAAAAGAAAGTCTCTGAGCTAGCAAAGCTTTACCGAATTTGGATTGTT
ATTGGCAGTATGCCGATAAGCACAGCTAAAGGCGTGACTACCACAACTTTGGTGGTTGATGATTTTGGTTGCTTAGTGGC
CCATTACGATAAGCTACACATGTTTGATGTGGATGTTGCTGATGCACATAAGTGCTATCGAGAATCGGATATTTTCACGC
CCGGTGACCGAGTGGTAACAACGGAAACGCCTTTTGGTCGCTTAGGTTTGAGTATTTGTTATGATGTGCGCTTTCCGCAC
TTGTATTCAGAGTTACGCAAGCAAGGTGCACAAATCATAGTGGTACCGGCAGCTTTTACCGCAGTAACAGGGCAAGCTCA
CTGGGAAGCATTATTAAGATGCCGCGCGATCGAAACGCAATCGTGGATTATCGCGGTAGGGCAAGGCGGAAATCACCCTT
GCCAAAGAGAAACATGGGGACACTCAATGGTGGTTGATCCATGGGGACGAGTGGTTGCACAACTAGACCAAGATCCTAAA
AGTATGGTGGTTGAGATAGACACATCCAGTTGCGAATCAATCAGGCAAAATATGCCAATCGCGCAGCATTCTCGATTTAC
CAATCAATTTTAA

Upstream 100 bases:

>100_bases
AATGAACCTTAAATTAGCCGAAAAGACCTTAGTATCCTAATCAGCTAATATACGGTGAAATGCTGATTTCTGAATCATAA
TGAATGGAGGAGCGATACAC

Downstream 100 bases:

>100_bases
TTACAAATAAGAGCCATTTATGAGCATCAATCAAATTGAAGAAGCGCTACTAAACCCAACAGGGCTGACGGAGCAAAATA
TCGCAGATACATTGGCGAGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MDCVGLIQMTSGPRPDLNFDYLAQEVAKCKELGAKWVVCPENALVFGSKADYHQYAEPLNDGPLQKKVSELAKLYRIWIV
IGSMPISTAKGVTTTTLVVDDFGCLVAHYDKLHMFDVDVADAHKCYRESDIFTPGDRVVTTETPFGRLGLSICYDVRFPH
LYSELRKQGAQIIVVPAAFTAVTGQAHWEALLRCRAIETQSWIIAVGQGGNHPCQRETWGHSMVVDPWGRVVAQLDQDPK
SMVVEIDTSSCESIRQNMPIAQHSRFTNQF

Sequences:

>Translated_270_residues
MDCVGLIQMTSGPRPDLNFDYLAQEVAKCKELGAKWVVCPENALVFGSKADYHQYAEPLNDGPLQKKVSELAKLYRIWIV
IGSMPISTAKGVTTTTLVVDDFGCLVAHYDKLHMFDVDVADAHKCYRESDIFTPGDRVVTTETPFGRLGLSICYDVRFPH
LYSELRKQGAQIIVVPAAFTAVTGQAHWEALLRCRAIETQSWIIAVGQGGNHPCQRETWGHSMVVDPWGRVVAQLDQDPK
SMVVEIDTSSCESIRQNMPIAQHSRFTNQF
>Mature_270_residues
MDCVGLIQMTSGPRPDLNFDYLAQEVAKCKELGAKWVVCPENALVFGSKADYHQYAEPLNDGPLQKKVSELAKLYRIWIV
IGSMPISTAKGVTTTTLVVDDFGCLVAHYDKLHMFDVDVADAHKCYRESDIFTPGDRVVTTETPFGRLGLSICYDVRFPH
LYSELRKQGAQIIVVPAAFTAVTGQAHWEALLRCRAIETQSWIIAVGQGGNHPCQRETWGHSMVVDPWGRVVAQLDQDPK
SMVVEIDTSSCESIRQNMPIAQHSRFTNQF

Specific function: Unknown

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI297632348, Length=271, Percent_Identity=36.5313653136531, Blast_Score=171, Evalue=9e-43,
Organism=Homo sapiens, GI297632350, Length=271, Percent_Identity=36.5313653136531, Blast_Score=170, Evalue=1e-42,
Organism=Homo sapiens, GI5031947, Length=271, Percent_Identity=36.5313653136531, Blast_Score=170, Evalue=1e-42,
Organism=Homo sapiens, GI9910460, Length=235, Percent_Identity=37.4468085106383, Blast_Score=157, Evalue=9e-39,
Organism=Homo sapiens, GI297632346, Length=195, Percent_Identity=32.8205128205128, Blast_Score=96, Evalue=3e-20,
Organism=Escherichia coli, GI1786412, Length=188, Percent_Identity=29.7872340425532, Blast_Score=68, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17556280, Length=266, Percent_Identity=38.3458646616541, Blast_Score=180, Evalue=6e-46,
Organism=Saccharomyces cerevisiae, GI6323383, Length=272, Percent_Identity=32.7205882352941, Blast_Score=152, Evalue=4e-38,
Organism=Saccharomyces cerevisiae, GI6322335, Length=196, Percent_Identity=38.265306122449, Blast_Score=149, Evalue=6e-37,
Organism=Drosophila melanogaster, GI17933642, Length=267, Percent_Identity=39.3258426966292, Blast_Score=176, Evalue=1e-44,
Organism=Drosophila melanogaster, GI21355835, Length=243, Percent_Identity=31.6872427983539, Blast_Score=143, Evalue=1e-34,
Organism=Drosophila melanogaster, GI21358471, Length=220, Percent_Identity=24.5454545454545, Blast_Score=68, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010
- InterPro:   IPR001110 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 30147; Mature: 30147

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: PS50263 CN_HYDROLASE ; PS00290 IG_MHC ; PS01227 UPF0012

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDCVGLIQMTSGPRPDLNFDYLAQEVAKCKELGAKWVVCPENALVFGSKADYHQYAEPLN
CCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCEEECCCCCHHHHHCCCC
DGPLQKKVSELAKLYRIWIVIGSMPISTAKGVTTTTLVVDDFGCLVAHYDKLHMFDVDVA
CCHHHHHHHHHHHHHHHHHEECCCCCCCCCCCEEEEEEEECHHHHHHHCCEEEEEECCHH
DAHKCYRESDIFTPGDRVVTTETPFGRLGLSICYDVRFPHLYSELRKQGAQIIVVPAAFT
HHHHHHHHCCCCCCCCEEEEECCCCCHHCCEEEEECCCHHHHHHHHHCCCEEEEEECHHH
AVTGQAHWEALLRCRAIETQSWIIAVGQGGNHPCQRETWGHSMVVDPWGRVVAQLDQDPK
HHCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCEEECHHHHHHHHHCCCCC
SMVVEIDTSSCESIRQNMPIAQHSRFTNQF
CEEEEECCHHHHHHHHCCCHHHHHHHCCCC
>Mature Secondary Structure
MDCVGLIQMTSGPRPDLNFDYLAQEVAKCKELGAKWVVCPENALVFGSKADYHQYAEPLN
CCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCEEECCCCCHHHHHCCCC
DGPLQKKVSELAKLYRIWIVIGSMPISTAKGVTTTTLVVDDFGCLVAHYDKLHMFDVDVA
CCHHHHHHHHHHHHHHHHHEECCCCCCCCCCCEEEEEEEECHHHHHHHCCEEEEEECCHH
DAHKCYRESDIFTPGDRVVTTETPFGRLGLSICYDVRFPHLYSELRKQGAQIIVVPAAFT
HHHHHHHHCCCCCCCCEEEEECCCCCHHCCEEEEECCCHHHHHHHHHCCCEEEEEECHHH
AVTGQAHWEALLRCRAIETQSWIIAVGQGGNHPCQRETWGHSMVVDPWGRVVAQLDQDPK
HHCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCEEECHHHHHHHHHCCCCC
SMVVEIDTSSCESIRQNMPIAQHSRFTNQF
CEEEEECCHHHHHHHHCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]