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The map label for this gene is tldD [H]

Identifier: 218708388

GI number: 218708388

Start: 346223

End: 347668

Strand: Direct

Name: tldD [H]

Synonym: VS_0348

Alternate gene names: 218708388

Gene position: 346223-347668 (Clockwise)

Preceding gene: 218708387

Following gene: 218708390

Centisome position: 10.49

GC content: 46.89

Gene sequence:

>1446_bases
ATGAGCATCAATCAAATTGAAGAAGCGCTACTAAACCCAACAGGGCTGACGGAGCAAAATATCGCAGATACATTGGCGAG
CATTGCTACCCGCCAAATTGATTATGCTGATATCTACTTTCAGTCAAGCTGGCATGAATCTTTAGTGCTAGAAGACAGCA
TTATTAAAGACGGCTCTTTCAATATCGATTGTGGTGTTGGTGTTCGTGCAGTATCTGGTGAAAAAACCGGTTTTGCTTAC
TCTGACCAAATCCAACTGGATGGGCTTAAGCAGAGCGCAATTGCAGCTCGTGGTATCGCTAAACAAGGCCAAAACGGTAA
GGTACAAGCTTTCAAGCGTAACTCTAACCAAGCTTACTATGATGCAGTTAACCCGCTAGCAAGCTGGGAAAAACAGCAAA
AGACAGAATTACTTAAAGCGCTTGATGCTTACATTCGCACTAAAGAACCGATGGTAACTGAAGTATCGGTGAGCCTAAGT
GGTGTACATGAACAGATGCTCGTTGCGGCAACTGATGGTACTTTCGCTGGTGATATTCGCCCGTTGGTTCGTCTATCAAT
TAGCGTACTTGCACAGAAAGGCGATCGTCGTGAACGTGGCAGTGCCGGTGGCGGTGGTCGTTTTGGTTACGATTTCTTCT
TAAGTGATGCTAACGGTTCTCAAGTTGCTTACCAATTCGCTGATGAAGCCATTCGCCAAGCATTAGTTAACCTTGAAGCG
GTTGCTGCGCCTGCTGGTGCAATGCCTGTGGTTCTTGGTTCTGGTTGGCCGGGTGTTCTACTGCATGAAGCGGTAGGCCA
CGGTTTAGAAGGTGATTTCAACCGTAAAGAGTCTTCAGTATTTTCTGGCAAAATCGGCGAGCAAGTTACATCAAGCCTAT
GTACGATTGTTGATGACGGCACATTAACAGATCTACGCGGTTCATTGAATGTTGATGATGAGGGTGTTAATGGTCAGTAC
AATACGCTAATCGAAAACGGCATCCTAAAAGGTTACATGCAAGATAAGCTAAACGCTCGTCTAATGGGTGTCGCGCCGAC
AGGTAATGGTCGTCGTGAGTCTTACGCGCATCTTCCAATGCCACGTATGACGAATACATACATGCTGCCGGGCGAACACA
CACCGGAAGAGATCATTGCAACGGTTGAGAAAGGCATCTACGCACCGAACTTCGGTGGCGGTCAGGTTGATATCACATCA
GGTAAGTTTGTGTTCTCAGCTTCTGAAGCGTACATGATTGAAAACGGCAAGATCACTCACCCAGTGAAGGGCGCGACGCT
GATCGGTTCTGGTATCGAAGCAATGCAGCAGGTGTCTATGGTCGGTAATGACCTAAGCATTGACCGTGGTGTTGGTGTTT
GTGGTAAGGCTGGTCAAAGTGTACCAGTGGGTGTTGGTCAACCAACATTGAAACTAGACTCGCTAACGGTTGGTGGTACT
GAGTAA

Upstream 100 bases:

>100_bases
GAGATAGACACATCCAGTTGCGAATCAATCAGGCAAAATATGCCAATCGCGCAGCATTCTCGATTTACCAATCAATTTTA
ATTACAAATAAGAGCCATTT

Downstream 100 bases:

>100_bases
TTCAGGTCAGCAGCACGAGTTAATTTCAAAATCTCTCGTCATAAAATAGATTGAAAGCGCCTCTATTGTGAGGCGCTTTT
TGTTTATAGGTTACTGGTTC

Product: putative peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 480

Protein sequence:

>481_residues
MSINQIEEALLNPTGLTEQNIADTLASIATRQIDYADIYFQSSWHESLVLEDSIIKDGSFNIDCGVGVRAVSGEKTGFAY
SDQIQLDGLKQSAIAARGIAKQGQNGKVQAFKRNSNQAYYDAVNPLASWEKQQKTELLKALDAYIRTKEPMVTEVSVSLS
GVHEQMLVAATDGTFAGDIRPLVRLSISVLAQKGDRRERGSAGGGGRFGYDFFLSDANGSQVAYQFADEAIRQALVNLEA
VAAPAGAMPVVLGSGWPGVLLHEAVGHGLEGDFNRKESSVFSGKIGEQVTSSLCTIVDDGTLTDLRGSLNVDDEGVNGQY
NTLIENGILKGYMQDKLNARLMGVAPTGNGRRESYAHLPMPRMTNTYMLPGEHTPEEIIATVEKGIYAPNFGGGQVDITS
GKFVFSASEAYMIENGKITHPVKGATLIGSGIEAMQQVSMVGNDLSIDRGVGVCGKAGQSVPVGVGQPTLKLDSLTVGGT
E

Sequences:

>Translated_481_residues
MSINQIEEALLNPTGLTEQNIADTLASIATRQIDYADIYFQSSWHESLVLEDSIIKDGSFNIDCGVGVRAVSGEKTGFAY
SDQIQLDGLKQSAIAARGIAKQGQNGKVQAFKRNSNQAYYDAVNPLASWEKQQKTELLKALDAYIRTKEPMVTEVSVSLS
GVHEQMLVAATDGTFAGDIRPLVRLSISVLAQKGDRRERGSAGGGGRFGYDFFLSDANGSQVAYQFADEAIRQALVNLEA
VAAPAGAMPVVLGSGWPGVLLHEAVGHGLEGDFNRKESSVFSGKIGEQVTSSLCTIVDDGTLTDLRGSLNVDDEGVNGQY
NTLIENGILKGYMQDKLNARLMGVAPTGNGRRESYAHLPMPRMTNTYMLPGEHTPEEIIATVEKGIYAPNFGGGQVDITS
GKFVFSASEAYMIENGKITHPVKGATLIGSGIEAMQQVSMVGNDLSIDRGVGVCGKAGQSVPVGVGQPTLKLDSLTVGGT
E
>Mature_480_residues
SINQIEEALLNPTGLTEQNIADTLASIATRQIDYADIYFQSSWHESLVLEDSIIKDGSFNIDCGVGVRAVSGEKTGFAYS
DQIQLDGLKQSAIAARGIAKQGQNGKVQAFKRNSNQAYYDAVNPLASWEKQQKTELLKALDAYIRTKEPMVTEVSVSLSG
VHEQMLVAATDGTFAGDIRPLVRLSISVLAQKGDRRERGSAGGGGRFGYDFFLSDANGSQVAYQFADEAIRQALVNLEAV
AAPAGAMPVVLGSGWPGVLLHEAVGHGLEGDFNRKESSVFSGKIGEQVTSSLCTIVDDGTLTDLRGSLNVDDEGVNGQYN
TLIENGILKGYMQDKLNARLMGVAPTGNGRRESYAHLPMPRMTNTYMLPGEHTPEEIIATVEKGIYAPNFGGGQVDITSG
KFVFSASEAYMIENGKITHPVKGATLIGSGIEAMQQVSMVGNDLSIDRGVGVCGKAGQSVPVGVGQPTLKLDSLTVGGTE

Specific function: Suppresses the inhibitory activity of the carbon storage regulator (CsrA) [H]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=480, Percent_Identity=69.1666666666667, Blast_Score=661, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 51149; Mature: 51018

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSINQIEEALLNPTGLTEQNIADTLASIATRQIDYADIYFQSSWHESLVLEDSIIKDGSF
CCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCEEEEHHHCCCCCC
NIDCGVGVRAVSGEKTGFAYSDQIQLDGLKQSAIAARGIAKQGQNGKVQAFKRNSNQAYY
EEECCCCEEEECCCCCCCEECCEEEECCCHHHHHHHHHHHHCCCCCCEEEEEECCCCEEH
DAVNPLASWEKQQKTELLKALDAYIRTKEPMVTEVSVSLSGVHEQMLVAATDGTFAGDIR
HHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHCCCEEEEEEECCCCCCCCHH
PLVRLSISVLAQKGDRRERGSAGGGGRFGYDFFLSDANGSQVAYQFADEAIRQALVNLEA
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCEEHHHHHHHHHHHHHHHHHH
VAAPAGAMPVVLGSGWPGVLLHEAVGHGLEGDFNRKESSVFSGKIGEQVTSSLCTIVDDG
HHCCCCCCEEEECCCCCHHHHHHHHCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHEECCC
TLTDLRGSLNVDDEGVNGQYNTLIENGILKGYMQDKLNARLMGVAPTGNGRRESYAHLPM
CEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEECCCC
PRMTNTYMLPGEHTPEEIIATVEKGIYAPNFGGGQVDITSGKFVFSASEAYMIENGKITH
CCCCCEEECCCCCCHHHHHHHHHHCCCCCCCCCCEEEEECCEEEEECCCEEEEECCEECC
PVKGATLIGSGIEAMQQVSMVGNDLSIDRGVGVCGKAGQSVPVGVGQPTLKLDSLTVGGT
CCCCCEEECHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCC
E
C
>Mature Secondary Structure 
SINQIEEALLNPTGLTEQNIADTLASIATRQIDYADIYFQSSWHESLVLEDSIIKDGSF
CHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCEEEEHHHCCCCCC
NIDCGVGVRAVSGEKTGFAYSDQIQLDGLKQSAIAARGIAKQGQNGKVQAFKRNSNQAYY
EEECCCCEEEECCCCCCCEECCEEEECCCHHHHHHHHHHHHCCCCCCEEEEEECCCCEEH
DAVNPLASWEKQQKTELLKALDAYIRTKEPMVTEVSVSLSGVHEQMLVAATDGTFAGDIR
HHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHCCCEEEEEEECCCCCCCCHH
PLVRLSISVLAQKGDRRERGSAGGGGRFGYDFFLSDANGSQVAYQFADEAIRQALVNLEA
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCEEHHHHHHHHHHHHHHHHHH
VAAPAGAMPVVLGSGWPGVLLHEAVGHGLEGDFNRKESSVFSGKIGEQVTSSLCTIVDDG
HHCCCCCCEEEECCCCCHHHHHHHHCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHEECCC
TLTDLRGSLNVDDEGVNGQYNTLIENGILKGYMQDKLNARLMGVAPTGNGRRESYAHLPM
CEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEECCCC
PRMTNTYMLPGEHTPEEIIATVEKGIYAPNFGGGQVDITSGKFVFSASEAYMIENGKITH
CCCCCEEECCCCCCHHHHHHHHHHCCCCCCCCCCEEEEECCEEEEECCCEEEEECCEECC
PVKGATLIGSGIEAMQQVSMVGNDLSIDRGVGVCGKAGQSVPVGVGQPTLKLDSLTVGGT
CCCCCEEECHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCC
E
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]