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The map label for this gene is rsgA1 [H]

Identifier: 218708316

GI number: 218708316

Start: 252534

End: 253589

Strand: Reverse

Name: rsgA1 [H]

Synonym: VS_0254

Alternate gene names: 218708316

Gene position: 253589-252534 (Counterclockwise)

Preceding gene: 218708318

Following gene: 218708315

Centisome position: 7.69

GC content: 45.93

Gene sequence:

>1056_bases
GTGGCTAAAAAAAAGAAGTTAACCAAAGGTCAGGTACGTCGCGTACGTAGCAACCAGAACAAGCGACTCAAGAAAGAAGA
TTCTATCCAATGGGACGAGAACATGCTTGGCGGAACAAAAAGCGGACTCGTGATTACGCGCTTTGGTCAACATGCCGATA
TCGAAGATCTTGAAACCAACGAAGTTCACCGTTGTAACTTACGCCGTAGTATTGAGACTTTAGTTTCTGGTGACCGAGTA
ACTTGGCGCGCAGGGCTTGAGTCAATGGCTGGCATCTCAGGTGTTGTCGAAGCCGTTGAGCCAAGAACATCAATGCTAAC
TCGCCCTGACTACTATGACGGCCTCAAACCGGTTGCCGCAAACGTAGACCAAATGGTTATCGTTTCAGCTGTACTACCAG
AGCTATCACTTAATATCATTGACCGCTACTTGATCGCCTCTGAAACGGTGAATATCGCCCCTTTAGTTGTACTCAATAAA
GTCGACTTGCTGACAGAACAACAAATTAGCGAATACCGCGAAACACTGAAGATATACGAGAAAATCGGCTATAAAGTCAT
GTTCGTGAGTAAAGAGTCGGGTTACGGCATCAAAGAGTTGGAAGCTGAACTGAAAGATCGTATCAACATTTTCGTTGGTC
AATCTGGCGTAGGTAAATCCAGCGTAGTGAATGCACTGATGCCAACATTGGACATTGAAGAAGGTGCAGTTTCTGAAAAC
TCAGGACTGGGTCAACACACCACCACAGCAGCGCGTTTGTATCACTTCCCTTCTGGTGGTGATCTTATCGATTCCCCTGG
AGTACGTGAATTCGGCCTATGGCATTTAGAACCCGATGAAGTCACAGATGCTTTCATTGAATTCAAGCCATACCTAGGTG
GCTGTAAGTTCCGCGATTGTAAACACAATGACGACCCAGGATGTCTTCTGCGTGAAGCCGTTGAAGACGGAAAAATTAGC
CGCTTACGCTTTGCTAGCTACCACCGCATTATTGAAACAATGGCTGACAACAAAGATAACCGTCAGTACTCACGAAGCAA
GAAAGCCGATCTCTAA

Upstream 100 bases:

>100_bases
CTATACTCAAACTAGCTTTAGAGCCATCGAAATCATATGGCAGTAGCAACATCCTGTTTGAGTTCCCAATCATCAAGTTA
GATGTGTTAAGTGAAAAATT

Downstream 100 bases:

>100_bases
TCGCGTTTTTGTGAACAAATGTGTGCATTTACTGACAATTGGCGCGAACTTAAGTAACATCTCGCGCCCTAAACCGTCAT
CGACAGATTTAATTGAAAAA

Product: ribosome-associated GTPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MAKKKKLTKGQVRRVRSNQNKRLKKEDSIQWDENMLGGTKSGLVITRFGQHADIEDLETNEVHRCNLRRSIETLVSGDRV
TWRAGLESMAGISGVVEAVEPRTSMLTRPDYYDGLKPVAANVDQMVIVSAVLPELSLNIIDRYLIASETVNIAPLVVLNK
VDLLTEQQISEYRETLKIYEKIGYKVMFVSKESGYGIKELEAELKDRINIFVGQSGVGKSSVVNALMPTLDIEEGAVSEN
SGLGQHTTTAARLYHFPSGGDLIDSPGVREFGLWHLEPDEVTDAFIEFKPYLGGCKFRDCKHNDDPGCLLREAVEDGKIS
RLRFASYHRIIETMADNKDNRQYSRSKKADL

Sequences:

>Translated_351_residues
MAKKKKLTKGQVRRVRSNQNKRLKKEDSIQWDENMLGGTKSGLVITRFGQHADIEDLETNEVHRCNLRRSIETLVSGDRV
TWRAGLESMAGISGVVEAVEPRTSMLTRPDYYDGLKPVAANVDQMVIVSAVLPELSLNIIDRYLIASETVNIAPLVVLNK
VDLLTEQQISEYRETLKIYEKIGYKVMFVSKESGYGIKELEAELKDRINIFVGQSGVGKSSVVNALMPTLDIEEGAVSEN
SGLGQHTTTAARLYHFPSGGDLIDSPGVREFGLWHLEPDEVTDAFIEFKPYLGGCKFRDCKHNDDPGCLLREAVEDGKIS
RLRFASYHRIIETMADNKDNRQYSRSKKADL
>Mature_350_residues
AKKKKLTKGQVRRVRSNQNKRLKKEDSIQWDENMLGGTKSGLVITRFGQHADIEDLETNEVHRCNLRRSIETLVSGDRVT
WRAGLESMAGISGVVEAVEPRTSMLTRPDYYDGLKPVAANVDQMVIVSAVLPELSLNIIDRYLIASETVNIAPLVVLNKV
DLLTEQQISEYRETLKIYEKIGYKVMFVSKESGYGIKELEAELKDRINIFVGQSGVGKSSVVNALMPTLDIEEGAVSENS
GLGQHTTTAARLYHFPSGGDLIDSPGVREFGLWHLEPDEVTDAFIEFKPYLGGCKFRDCKHNDDPGCLLREAVEDGKISR
LRFASYHRIIETMADNKDNRQYSRSKKADL

Specific function: May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover [H]

COG id: COG1162

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 engC GTPase domain [H]

Homologues:

Organism=Escherichia coli, GI87082381, Length=345, Percent_Identity=58.8405797101449, Blast_Score=431, Evalue=1e-122,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010914
- InterPro:   IPR004881 [H]

Pfam domain/function: PF03193 DUF258 [H]

EC number: NA

Molecular weight: Translated: 39381; Mature: 39250

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS50936 ENGC_GTPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKKKKLTKGQVRRVRSNQNKRLKKEDSIQWDENMLGGTKSGLVITRFGQHADIEDLETN
CCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHCCCCCCCEEEEECCCCCCCCCCCCC
EVHRCNLRRSIETLVSGDRVTWRAGLESMAGISGVVEAVEPRTSMLTRPDYYDGLKPVAA
CHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHCCCCHHHC
NVDQMVIVSAVLPELSLNIIDRYLIASETVNIAPLVVLNKVDLLTEQQISEYRETLKIYE
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHH
KIGYKVMFVSKESGYGIKELEAELKDRINIFVGQSGVGKSSVVNALMPTLDIEEGAVSEN
HCCCEEEEEECCCCCCHHHHHHHHHHCEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCC
SGLGQHTTTAARLYHFPSGGDLIDSPGVREFGLWHLEPDEVTDAFIEFKPYLGGCKFRDC
CCCCCHHHHHHHEEECCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHCCCCCCCCCCCC
KHNDDPGCLLREAVEDGKISRLRFASYHRIIETMADNKDNRQYSRSKKADL
CCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCC
>Mature Secondary Structure 
AKKKKLTKGQVRRVRSNQNKRLKKEDSIQWDENMLGGTKSGLVITRFGQHADIEDLETN
CCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHCCCCCCCEEEEECCCCCCCCCCCCC
EVHRCNLRRSIETLVSGDRVTWRAGLESMAGISGVVEAVEPRTSMLTRPDYYDGLKPVAA
CHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHCCCCHHHC
NVDQMVIVSAVLPELSLNIIDRYLIASETVNIAPLVVLNKVDLLTEQQISEYRETLKIYE
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHH
KIGYKVMFVSKESGYGIKELEAELKDRINIFVGQSGVGKSSVVNALMPTLDIEEGAVSEN
HCCCEEEEEECCCCCCHHHHHHHHHHCEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCC
SGLGQHTTTAARLYHFPSGGDLIDSPGVREFGLWHLEPDEVTDAFIEFKPYLGGCKFRDC
CCCCCHHHHHHHEEECCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHCCCCCCCCCCCC
KHNDDPGCLLREAVEDGKISRLRFASYHRIIETMADNKDNRQYSRSKKADL
CCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GTP [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]