Click here to switch to the map view.

The map label for this gene is kdsC [H]

Identifier: 218708279

GI number: 218708279

Start: 211432

End: 211995

Strand: Direct

Name: kdsC [H]

Synonym: VS_0217

Alternate gene names: 218708279

Gene position: 211432-211995 (Clockwise)

Preceding gene: 218708278

Following gene: 218708280

Centisome position: 6.41

GC content: 38.12

Gene sequence:

>564_bases
ATGTTGGATAAAAAGGTCTGTAAAAATATCAAAATGGTTTTACTTGATGTTGATGGAGTAATGACGGATGGCTCTATCTA
TATTAATCAAGACGGTGAGTTCTTCAAATCATTTAATGTTAAAGACGGTTTGGCTGTCGAGTTATTACGCAGCCATAATA
TTCTTGTTGGTATTATTTCAGGTAAAGCAAGCGCAGCTTTAGATACTCGATGCCAGCAACTGGGTTTTGATGAAATAATT
ACTGGTTGTAAAAATAAACTTCCCGCTTTAATTGATATTTGCTCCAAATATAAAATCACGTCAGAACAAATTTCTTTTCT
GGGTGATGATGTGCTTGATATTCCGATCTTTGAGAAGGTAGGGCTGTCCGCTGCTCCAATTGACGCTCATAAATTAGCGA
TCGATAGTGCTGACTGGGTTTCATCCCTTAAAGGGGGCGAGGGGATGGTAAGAGAGTTTGTTGACCTATTGTTGGTAACG
CAACTTGATAAGCCACTAAAAGAGGTCTACGAGCCATTACTTAACAAAATCCGTTTAGATGATGTAGCAACAATGGAGCA
ATAA

Upstream 100 bases:

>100_bases
TGTTGCCACTGAAACATATGGAAGAGCTATTAGAGACTTTACTTGAGATCGATGAAGTTGTTCATCGTCGCGCTTTTATA
GAGTCTAAACTGGTTTAATT

Downstream 100 bases:

>100_bases
AGTATGGGGGTGAAAGTTGTAATTCCAGCGCGATATGGCTCATCTAGGTTGCCTGGTAAACCGTTATTAACTTTACTTGA
TAAACCTGTTATTTGGCATG

Product: putative 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase

Products: NA

Alternate protein names: KDO 8-P phosphatase [H]

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MLDKKVCKNIKMVLLDVDGVMTDGSIYINQDGEFFKSFNVKDGLAVELLRSHNILVGIISGKASAALDTRCQQLGFDEII
TGCKNKLPALIDICSKYKITSEQISFLGDDVLDIPIFEKVGLSAAPIDAHKLAIDSADWVSSLKGGEGMVREFVDLLLVT
QLDKPLKEVYEPLLNKIRLDDVATMEQ

Sequences:

>Translated_187_residues
MLDKKVCKNIKMVLLDVDGVMTDGSIYINQDGEFFKSFNVKDGLAVELLRSHNILVGIISGKASAALDTRCQQLGFDEII
TGCKNKLPALIDICSKYKITSEQISFLGDDVLDIPIFEKVGLSAAPIDAHKLAIDSADWVSSLKGGEGMVREFVDLLLVT
QLDKPLKEVYEPLLNKIRLDDVATMEQ
>Mature_187_residues
MLDKKVCKNIKMVLLDVDGVMTDGSIYINQDGEFFKSFNVKDGLAVELLRSHNILVGIISGKASAALDTRCQQLGFDEII
TGCKNKLPALIDICSKYKITSEQISFLGDDVLDIPIFEKVGLSAAPIDAHKLAIDSADWVSSLKGGEGMVREFVDLLLVT
QLDKPLKEVYEPLLNKIRLDDVATMEQ

Specific function: Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate [H]

COG id: COG1778

COG function: function code R; Low specificity phosphatase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsC family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=158, Percent_Identity=29.1139240506329, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI2367202, Length=154, Percent_Identity=44.8051948051948, Blast_Score=144, Evalue=4e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006549
- InterPro:   IPR010023 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: =3.1.3.45 [H]

Molecular weight: Translated: 20589; Mature: 20589

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDKKVCKNIKMVLLDVDGVMTDGSIYINQDGEFFKSFNVKDGLAVELLRSHNILVGIIS
CCCHHHHCCCEEEEEECCCEEECCEEEECCCCHHHHHCCCCCCHHHHHHHCCCEEEEEEC
GKASAALDTRCQQLGFDEIITGCKNKLPALIDICSKYKITSEQISFLGDDVLDIPIFEKV
CCCHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHCCCCCCCCCHHHC
GLSAAPIDAHKLAIDSADWVSSLKGGEGMVREFVDLLLVTQLDKPLKEVYEPLLNKIRLD
CCCCCCCCHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCC
DVATMEQ
HHHCCCC
>Mature Secondary Structure
MLDKKVCKNIKMVLLDVDGVMTDGSIYINQDGEFFKSFNVKDGLAVELLRSHNILVGIIS
CCCHHHHCCCEEEEEECCCEEECCEEEECCCCHHHHHCCCCCCHHHHHHHCCCEEEEEEC
GKASAALDTRCQQLGFDEIITGCKNKLPALIDICSKYKITSEQISFLGDDVLDIPIFEKV
CCCHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHCCCCCCCCCHHHC
GLSAAPIDAHKLAIDSADWVSSLKGGEGMVREFVDLLLVTQLDKPLKEVYEPLLNKIRLD
CCCCCCCCHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCC
DVATMEQ
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]