Click here to switch to the map view.

The map label for this gene is wzb [C]

Identifier: 218708276

GI number: 218708276

Start: 207434

End: 207874

Strand: Direct

Name: wzb [C]

Synonym: VS_0214

Alternate gene names: 218708276

Gene position: 207434-207874 (Clockwise)

Preceding gene: 218708275

Following gene: 218708277

Centisome position: 6.29

GC content: 44.67

Gene sequence:

>441_bases
ATGTTTAATAAAATTTTAGTGGTCTGCGTAGGTAACATTTGTCGTTCCCCGACTGGAGAGCGTGTTCTTCAAAAGTTGCT
GCCTAATAAAGAAGTAGCCTCTGCCGGCATTGCTGCTGAAAAAAGTCGTTTAATTGGCAAGCCAGCTGACGATACTGCGA
TTTTAATTGCCGCTGAAAACGGAGTAGACGTTGAAAGCCATCAGTCTCAACAAGTCACTCCTCAGCTTTGTGCTCAGTAT
GATTTAATCTTGGTGATGGAGAAGGGCCACTTAGAAGCGCTCACTCAAATCTCACCAGAGGCACGCGGTAAAACCATGTT
GTTTGGGCAGTGGGTTGGCCAACAAGATATTCCTGATCCTTACCGTCAAAGTCGTGAGGCATTTGAGCACGTTTATAAAT
TGATTGATGAAGCAGCGTATGCTTGGGCGAAAAGACTGTAA

Upstream 100 bases:

>100_bases
CAGGTCACATTTCATATGTGGCCTGATTTTTATGTTTAGAAGCTCGTTTGGTTTATAAGTATGTTTAGCTTATTAAGCCC
ATTACAGTTAGAAGTCAGTT

Downstream 100 bases:

>100_bases
CTGATGCTGTCATTCAATCTAGATAACATGCAGTTAAGCTTGAATTACCAACGATAGAATCTCATAAGAGAGAAGGGTAC
GTAAGCCGTACGTCACTTAT

Product: putative tyrosine-phosphatase

Products: NA

Alternate protein names: ORF5 [H]

Number of amino acids: Translated: 146; Mature: 146

Protein sequence:

>146_residues
MFNKILVVCVGNICRSPTGERVLQKLLPNKEVASAGIAAEKSRLIGKPADDTAILIAAENGVDVESHQSQQVTPQLCAQY
DLILVMEKGHLEALTQISPEARGKTMLFGQWVGQQDIPDPYRQSREAFEHVYKLIDEAAYAWAKRL

Sequences:

>Translated_146_residues
MFNKILVVCVGNICRSPTGERVLQKLLPNKEVASAGIAAEKSRLIGKPADDTAILIAAENGVDVESHQSQQVTPQLCAQY
DLILVMEKGHLEALTQISPEARGKTMLFGQWVGQQDIPDPYRQSREAFEHVYKLIDEAAYAWAKRL
>Mature_146_residues
MFNKILVVCVGNICRSPTGERVLQKLLPNKEVASAGIAAEKSRLIGKPADDTAILIAAENGVDVESHQSQQVTPQLCAQY
DLILVMEKGHLEALTQISPEARGKTMLFGQWVGQQDIPDPYRQSREAFEHVYKLIDEAAYAWAKRL

Specific function: Dephosphorylates Wzc. Required For The Extracellular Polysaccharide Colanic Acid Synthesis. Probably Involved In The Export Of Colanic Acid From The Cell To Medium. [C]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI4757714, Length=137, Percent_Identity=32.8467153284672, Blast_Score=70, Evalue=7e-13,
Organism=Homo sapiens, GI6005988, Length=137, Percent_Identity=30.6569343065693, Blast_Score=70, Evalue=9e-13,
Organism=Escherichia coli, GI1788375, Length=146, Percent_Identity=55.4794520547945, Blast_Score=172, Evalue=1e-44,
Organism=Escherichia coli, GI87081812, Length=145, Percent_Identity=55.1724137931034, Blast_Score=162, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 16190; Mature: 16190

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNKILVVCVGNICRSPTGERVLQKLLPNKEVASAGIAAEKSRLIGKPADDTAILIAAEN
CCCCEEHEEEHHHHCCCCHHHHHHHHCCCHHHHHHCCHHHHHHHCCCCCCCCEEEEEECC
GVDVESHQSQQVTPQLCAQYDLILVMEKGHLEALTQISPEARGKTMLFGQWVGQQDIPDP
CCCCCCCCCCCCCHHHHCCCCEEEEECCCCHHHHHHCCCCCCCCEEEEEECCCCCCCCCH
YRQSREAFEHVYKLIDEAAYAWAKRL
HHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFNKILVVCVGNICRSPTGERVLQKLLPNKEVASAGIAAEKSRLIGKPADDTAILIAAEN
CCCCEEHEEEHHHHCCCCHHHHHHHHCCCHHHHHHCCHHHHHHHCCCCCCCCEEEEEECC
GVDVESHQSQQVTPQLCAQYDLILVMEKGHLEALTQISPEARGKTMLFGQWVGQQDIPDP
CCCCCCCCCCCCCHHHHCCCCEEEEECCCCHHHHHHCCCCCCCCEEEEEECCCCCCCCCH
YRQSREAFEHVYKLIDEAAYAWAKRL
HHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7896702 [H]