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The map label for this gene is gpsA [H]

Identifier: 218708268

GI number: 218708268

Start: 198940

End: 200052

Strand: Reverse

Name: gpsA [H]

Synonym: VS_0205

Alternate gene names: 218708268

Gene position: 200052-198940 (Counterclockwise)

Preceding gene: 218708269

Following gene: 218708267

Centisome position: 6.06

GC content: 46.45

Gene sequence:

>1113_bases
TTGAAAGCTCCTCTGATTTTAGTGGATAGCTTTTCCAAGACTCTTCGATTTCCCTCATTATTTTTAGGTGGAAGCATGAC
AGAAACAACTCACTCGACAAACGCTTACGGCAAAGAGATCGCCATGGCAGTAATTGGCGCAGGTTCTTACGGAACATCTT
TGGCTATCTCTCTAGCGCGTAACGGTGCAAACGTTGTTCTGTGGGGGCATGATCCTGTTCACATGGCTCGTCTCGAATCT
GAGCGCGCAAATAATGAATTTCTACCAAATATCGACTTCCCAGAAAGCCTAATCATCGAGTCAGACCTTGAGAAGGCAGT
CACTGCAAGTCGTGATCTTCTTGTTGTCGTCCCTAGCCACGTATTTGGTATCGTTTTAAATAGCCTTAAGCCTCACTTAA
CCGACTGTTCTCGTATCTGCTGGGCTACTAAAGGTTTAGAGCCGGAAACTGGTCGCCTACTAAAGGATGTCGCTCACGAT
GTGCTTGGTGATGGGTACTCGTTAGCAGTTCTGTCAGGACCTACCTTCGCCAAAGAGCTAGCTATGGGTATGCCAACGGC
AATCTCTGTGGCTTCCCCTGATGCAAAATTCCTTGAGCAACTTCAAGAAAAAATTCACTGTGGCAAAACGTTTCGTGTGT
ACGCAAATTCAGATTTTATTGGCATGCAGCTTGGCGGTGCAGTGAAAAATGTCATCGCCATTGGTGCTGGCATGTCGGAT
GGTATTGGTTTTGGTGCCAATGCACGTACTGCACTTATCACTCGCGGTCTAGCTGAGATGAGTCGACTAGGCGCAGCTCT
TGGTGCGCAACCAGAAACCTTCATGGGCATGGCTGGATTGGGTGACCTAGTGCTAACCTGTACTGATAACCAATCACGTA
ACCGTCGCTTTGGTTTGGCGCTTGGCGCAGGTAAAGATGTAGATACAGCACAAGAAGAAATTGGCCAAGTAGTGGAAGGT
TATCGCAACACCAAAGAAGTTTGGTTACTATCAGAACGTATGGGCGTTGAAATGCCCATTGTTGAACAGATTTATCAAGT
GTTGTATCAAGGGAAAGATGCACACCTAGCAGCACAAGATCTGCTTGCTAGAGACAAAAAATCAGAAAGATAG

Upstream 100 bases:

>100_bases
TCAAAGTAGAGCTTAACTCTAACGATTCAAGCGCTAGTTAGCTTTTAAATGCACATCGCAACTTCTGCGATGTGCATTTT
TTCTTTACACTGTACTAAAA

Downstream 100 bases:

>100_bases
TAAGAGCAGATACGAAATTAGAGTAAGCGAGATACGAAGAGAGTTAGAGGTACGGGCAATCAAGATGCGAATAGCATAAA
GTAAATGACCCGAACAAAGT

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [H]

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MKAPLILVDSFSKTLRFPSLFLGGSMTETTHSTNAYGKEIAMAVIGAGSYGTSLAISLARNGANVVLWGHDPVHMARLES
ERANNEFLPNIDFPESLIIESDLEKAVTASRDLLVVVPSHVFGIVLNSLKPHLTDCSRICWATKGLEPETGRLLKDVAHD
VLGDGYSLAVLSGPTFAKELAMGMPTAISVASPDAKFLEQLQEKIHCGKTFRVYANSDFIGMQLGGAVKNVIAIGAGMSD
GIGFGANARTALITRGLAEMSRLGAALGAQPETFMGMAGLGDLVLTCTDNQSRNRRFGLALGAGKDVDTAQEEIGQVVEG
YRNTKEVWLLSERMGVEMPIVEQIYQVLYQGKDAHLAAQDLLARDKKSER

Sequences:

>Translated_370_residues
MKAPLILVDSFSKTLRFPSLFLGGSMTETTHSTNAYGKEIAMAVIGAGSYGTSLAISLARNGANVVLWGHDPVHMARLES
ERANNEFLPNIDFPESLIIESDLEKAVTASRDLLVVVPSHVFGIVLNSLKPHLTDCSRICWATKGLEPETGRLLKDVAHD
VLGDGYSLAVLSGPTFAKELAMGMPTAISVASPDAKFLEQLQEKIHCGKTFRVYANSDFIGMQLGGAVKNVIAIGAGMSD
GIGFGANARTALITRGLAEMSRLGAALGAQPETFMGMAGLGDLVLTCTDNQSRNRRFGLALGAGKDVDTAQEEIGQVVEG
YRNTKEVWLLSERMGVEMPIVEQIYQVLYQGKDAHLAAQDLLARDKKSER
>Mature_370_residues
MKAPLILVDSFSKTLRFPSLFLGGSMTETTHSTNAYGKEIAMAVIGAGSYGTSLAISLARNGANVVLWGHDPVHMARLES
ERANNEFLPNIDFPESLIIESDLEKAVTASRDLLVVVPSHVFGIVLNSLKPHLTDCSRICWATKGLEPETGRLLKDVAHD
VLGDGYSLAVLSGPTFAKELAMGMPTAISVASPDAKFLEQLQEKIHCGKTFRVYANSDFIGMQLGGAVKNVIAIGAGMSD
GIGFGANARTALITRGLAEMSRLGAALGAQPETFMGMAGLGDLVLTCTDNQSRNRRFGLALGAGKDVDTAQEEIGQVVEG
YRNTKEVWLLSERMGVEMPIVEQIYQVLYQGKDAHLAAQDLLARDKKSER

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI33695088, Length=335, Percent_Identity=26.865671641791, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI24307999, Length=339, Percent_Identity=25.6637168141593, Blast_Score=111, Evalue=1e-24,
Organism=Escherichia coli, GI1790037, Length=333, Percent_Identity=72.0720720720721, Blast_Score=489, Evalue=1e-140,
Organism=Caenorhabditis elegans, GI17507425, Length=358, Percent_Identity=24.3016759776536, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI32564399, Length=341, Percent_Identity=24.633431085044, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI32564403, Length=350, Percent_Identity=24.2857142857143, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI193210136, Length=338, Percent_Identity=23.9644970414201, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI193210134, Length=187, Percent_Identity=28.3422459893048, Blast_Score=75, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6324513, Length=345, Percent_Identity=27.2463768115942, Blast_Score=111, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6320181, Length=363, Percent_Identity=27.8236914600551, Blast_Score=104, Evalue=2e-23,
Organism=Drosophila melanogaster, GI17136202, Length=334, Percent_Identity=26.3473053892216, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI17136204, Length=334, Percent_Identity=26.3473053892216, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI17136200, Length=334, Percent_Identity=26.3473053892216, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI22026922, Length=285, Percent_Identity=25.9649122807018, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI45551945, Length=242, Percent_Identity=26.4462809917355, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281362270, Length=242, Percent_Identity=26.4462809917355, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N [H]

EC number: =1.1.1.94 [H]

Molecular weight: Translated: 39712; Mature: 39712

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS00957 NAD_G3PDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAPLILVDSFSKTLRFPSLFLGGSMTETTHSTNAYGKEIAMAVIGAGSYGTSLAISLAR
CCCCEEEEECHHHHHCCCHHHHCCCCCCCCCCCCHHHHHEEEEEEECCCCCCCEEEEEEC
NGANVVLWGHDPVHMARLESERANNEFLPNIDFPESLIIESDLEKAVTASRDLLVVVPSH
CCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECHH
VFGIVLNSLKPHLTDCSRICWATKGLEPETGRLLKDVAHDVLGDGYSLAVLSGPTFAKEL
HHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHH
AMGMPTAISVASPDAKFLEQLQEKIHCGKTFRVYANSDFIGMQLGGAVKNVIAIGAGMSD
HCCCCCEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCEEEEECCHHHHHHHHCCCCCCC
GIGFGANARTALITRGLAEMSRLGAALGAQPETFMGMAGLGDLVLTCTDNQSRNRRFGLA
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCEEEEECCCCCCCCEEEEE
LGAGKDVDTAQEEIGQVVEGYRNTKEVWLLSERMGVEMPIVEQIYQVLYQGKDAHLAAQD
ECCCCCCHHHHHHHHHHHHHHCCCHHEEEEHHHCCCCCHHHHHHHHHHHCCCCCHHHHHH
LLARDKKSER
HHHHHCCCCC
>Mature Secondary Structure
MKAPLILVDSFSKTLRFPSLFLGGSMTETTHSTNAYGKEIAMAVIGAGSYGTSLAISLAR
CCCCEEEEECHHHHHCCCHHHHCCCCCCCCCCCCHHHHHEEEEEEECCCCCCCEEEEEEC
NGANVVLWGHDPVHMARLESERANNEFLPNIDFPESLIIESDLEKAVTASRDLLVVVPSH
CCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECHH
VFGIVLNSLKPHLTDCSRICWATKGLEPETGRLLKDVAHDVLGDGYSLAVLSGPTFAKEL
HHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHH
AMGMPTAISVASPDAKFLEQLQEKIHCGKTFRVYANSDFIGMQLGGAVKNVIAIGAGMSD
HCCCCCEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCEEEEECCHHHHHHHHCCCCCCC
GIGFGANARTALITRGLAEMSRLGAALGAQPETFMGMAGLGDLVLTCTDNQSRNRRFGLA
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCEEEEECCCCCCCCEEEEE
LGAGKDVDTAQEEIGQVVEGYRNTKEVWLLSERMGVEMPIVEQIYQVLYQGKDAHLAAQD
ECCCCCCHHHHHHHHHHHHHHCCCHHEEEEHHHCCCCCHHHHHHHHHHHCCCCCHHHHHH
LLARDKKSER
HHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA