Click here to switch to the map view.

The map label for this gene is epsH [H]

Identifier: 218708203

GI number: 218708203

Start: 134655

End: 135248

Strand: Direct

Name: epsH [H]

Synonym: VS_0139

Alternate gene names: 218708203

Gene position: 134655-135248 (Clockwise)

Preceding gene: 218708202

Following gene: 218708204

Centisome position: 4.08

GC content: 43.77

Gene sequence:

>594_bases
GTGAAAACTAAGCAAACACAGCCAGGTTTCACCTTGATTGAGATTCTTTTGGTGTTGGTATTACTGTCAGTAACGGCGGT
CGCGGTGATCGCGACCATTCCGACCAATAGCAAAGATGTCGCTAAAAAATACGCTCAAAGCTTCTATCAACGAGTTCAAT
TACTCAATGAAGAGGCTATTTTGAGTGGCTTGGATTTTGGCGTTCGTGTCGATGAAAAGAAATCGACTTACGTTCTGATG
GCGCTTAAGTCAGAAGGTTGGCAAGAAGTCGAATTTGAAAAAATCCCCTCTTCAACTGAATTACCGGAAGAACTCGCGTT
GTCACTGACTTTAGGTGGTGGCGCATGGGAAGGCGATGATCGTTTGTTCAATCCCGGAAGCTTGTTTGATGAAGATATGT
TTGCGGATCTTGAAGAGGAAAAAAAGCCCAAGCCACCTCAGATATACATTTTGTCGAGTGCTGAAATGACGCCATTTGTA
TTGTCGTTTTATCCAAATACCGGAGACACCATACAAGATGGTTGGCGTATTCGAGTGTTGGATAATGGTGTGATTCGACT
GCTAGAGCCGGGAGAAGAAGATGAAGAGGAATAA

Upstream 100 bases:

>100_bases
GAACATGCAAGATTTCCAATAAGCTTCGGCTTATTGTTTTATAGGTTATTGAGCTTGATACGTTATTGATGGTAGGACGT
AAACAGATGGAGTCTACAAG

Downstream 100 bases:

>100_bases
CCGTTCTCCTTATCGTTCTCGTGGTATGCCTCTTGGTTCTCGAGGAATGACTCTGCTTGAAGTATTAGTTGCGCTCGCTA
TCTTCGCTACGGCGGCGATC

Product: type II secretory pathway pseudopilin EpsH

Products: NA

Alternate protein names: Cholera toxin secretion protein epsH [H]

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MKTKQTQPGFTLIEILLVLVLLSVTAVAVIATIPTNSKDVAKKYAQSFYQRVQLLNEEAILSGLDFGVRVDEKKSTYVLM
ALKSEGWQEVEFEKIPSSTELPEELALSLTLGGGAWEGDDRLFNPGSLFDEDMFADLEEEKKPKPPQIYILSSAEMTPFV
LSFYPNTGDTIQDGWRIRVLDNGVIRLLEPGEEDEEE

Sequences:

>Translated_197_residues
MKTKQTQPGFTLIEILLVLVLLSVTAVAVIATIPTNSKDVAKKYAQSFYQRVQLLNEEAILSGLDFGVRVDEKKSTYVLM
ALKSEGWQEVEFEKIPSSTELPEELALSLTLGGGAWEGDDRLFNPGSLFDEDMFADLEEEKKPKPPQIYILSSAEMTPFV
LSFYPNTGDTIQDGWRIRVLDNGVIRLLEPGEEDEEE
>Mature_197_residues
MKTKQTQPGFTLIEILLVLVLLSVTAVAVIATIPTNSKDVAKKYAQSFYQRVQLLNEEAILSGLDFGVRVDEKKSTYVLM
ALKSEGWQEVEFEKIPSSTELPEELALSLTLGGGAWEGDDRLFNPGSLFDEDMFADLEEEKKPKPPQIYILSSAEMTPFV
LSFYPNTGDTIQDGWRIRVLDNGVIRLLEPGEEDEEE

Specific function: Required for secretion of cholera toxin through the outer membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP H family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002416
- InterPro:   IPR012902
- InterPro:   IPR001120
- InterPro:   IPR022346 [H]

Pfam domain/function: PF12019 GspH [H]

EC number: NA

Molecular weight: Translated: 22062; Mature: 22062

Theoretical pI: Translated: 4.07; Mature: 4.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTKQTQPGFTLIEILLVLVLLSVTAVAVIATIPTNSKDVAKKYAQSFYQRVQLLNEEAI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCHHHH
LSGLDFGVRVDEKKSTYVLMALKSEGWQEVEFEKIPSSTELPEELALSLTLGGGAWEGDD
HHCCCCCEEECCCCCEEEEEEECCCCCCCCHHHHCCCCCCCHHHHEEEEEECCCCCCCCC
RLFNPGSLFDEDMFADLEEEKKPKPPQIYILSSAEMTPFVLSFYPNTGDTIQDGWRIRVL
CEECCCCCCCHHHHHCCHHHCCCCCCEEEEEECCCCCEEEEEEECCCCCCCCCCEEEEEE
DNGVIRLLEPGEEDEEE
CCCEEEEECCCCCCCCC
>Mature Secondary Structure
MKTKQTQPGFTLIEILLVLVLLSVTAVAVIATIPTNSKDVAKKYAQSFYQRVQLLNEEAI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCHHHH
LSGLDFGVRVDEKKSTYVLMALKSEGWQEVEFEKIPSSTELPEELALSLTLGGGAWEGDD
HHCCCCCEEECCCCCEEEEEEECCCCCCCCHHHHCCCCCCCHHHHEEEEEECCCCCCCCC
RLFNPGSLFDEDMFADLEEEKKPKPPQIYILSSAEMTPFVLSFYPNTGDTIQDGWRIRVL
CEECCCCCCCHHHHHCCHHHCCCCCCEEEEEECCCCCEEEEEEECCCCCCCCCCEEEEEE
DNGVIRLLEPGEEDEEE
CCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]