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The map label for this gene is epsC [H]

Identifier: 218708198

GI number: 218708198

Start: 128331

End: 129254

Strand: Direct

Name: epsC [H]

Synonym: VS_0134

Alternate gene names: 218708198

Gene position: 128331-129254 (Clockwise)

Preceding gene: 218708192

Following gene: 218708199

Centisome position: 3.89

GC content: 45.35

Gene sequence:

>924_bases
GTGAACTTTTTAGAGCTCAAGAATCGCGCAGGAAATTCTCCTGTGTTGAGCCGCTTATTAGAAAATGGATTTGTACTTCA
GCAGAAACTAAGCCTAGCGATGTGTTGTATGTTGATTGCAGCTTCCGCATGGATTTTAGGGCAGCTTGCATGGTTTATTG
AACCTGCTGAGCAAACCGTCGTGCCTTGGAAAGCAACAGCTTCATCATTTTCTACTCCTCAATCGACCCTTGATATCTCT
TCTTTGCAGCGGAGCAACCTTTTTGGTGCCTATAACCCAACCACGCCAGTTGTGGTTGAACAGCAAGTTATCCAAGATGC
GCCAAAGACACGATTAAATCTAGTTTTGGTCGGTGCTGTTGCCAGTTCTAATCCAAAACGGAGCTTAGCGGTGATCGCTA
ATCGCGGTACGCAGGCGACCTACGGAATTAATGAAGAGATAGAAGGCACTAGAGCTAAGCTTAAAGCCGTATTAGTCGAC
CGTGTCATTATTGATAACTCAGGTCGAGACGAAACCTTGATGCTTGAAGGTATTGAGTACAAGCGTTTAGCTGTCTCAGC
CCCTGCGCCACCTCGCGCTTCTTCTTCGGTTCGTGGTAATAACCCTGCTTCAGCAGAGCAAAAGCTAGATGAAATTAAAG
CGAAGATAATGAAAGATCCGCAACAAATCTTCCAATATGTTCGACTGTCCCAGGTCAAGCGCGACGATAAAGTGATTGGT
TATCGAGTGAGTCCAGGCAAAGATTCAGAACTTTTTAACTCAGTAGGGCTCCAAAACGGAGATATCGCGACTCAGTTAAA
TGGGCAAGACCTGACAGACCCCGCTGCTATGGGCAACATATTCCGTTCTATCTCAGAGCTGACAGAGCTAAATCTCGTCG
TCGAGAGAGATGGTCAACAACATGAAGTGTTTATTGAATTTTAA

Upstream 100 bases:

>100_bases
GGATCTTATGCTTAAATAAGCTTGGTATCGAACGAATGAATAAAAAAGCTGAAAGTTTAATGATTTGCAGCATTTGTCGT
CATGAAAAGGGGCAAGGAAA

Downstream 100 bases:

>100_bases
AACTTTGCGTCTAACGAAGGACGAAAGTGTAGGAGAAGTACGTGAAGCATTGGTTTAAGAAAAGTGCATGGTTATTGGCA
GGAAGCTTAATCTGCACACC

Product: type II secretory pathway subunit EpsC

Products: NA

Alternate protein names: Cholera toxin secretion protein epsC [H]

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MNFLELKNRAGNSPVLSRLLENGFVLQQKLSLAMCCMLIAASAWILGQLAWFIEPAEQTVVPWKATASSFSTPQSTLDIS
SLQRSNLFGAYNPTTPVVVEQQVIQDAPKTRLNLVLVGAVASSNPKRSLAVIANRGTQATYGINEEIEGTRAKLKAVLVD
RVIIDNSGRDETLMLEGIEYKRLAVSAPAPPRASSSVRGNNPASAEQKLDEIKAKIMKDPQQIFQYVRLSQVKRDDKVIG
YRVSPGKDSELFNSVGLQNGDIATQLNGQDLTDPAAMGNIFRSISELTELNLVVERDGQQHEVFIEF

Sequences:

>Translated_307_residues
MNFLELKNRAGNSPVLSRLLENGFVLQQKLSLAMCCMLIAASAWILGQLAWFIEPAEQTVVPWKATASSFSTPQSTLDIS
SLQRSNLFGAYNPTTPVVVEQQVIQDAPKTRLNLVLVGAVASSNPKRSLAVIANRGTQATYGINEEIEGTRAKLKAVLVD
RVIIDNSGRDETLMLEGIEYKRLAVSAPAPPRASSSVRGNNPASAEQKLDEIKAKIMKDPQQIFQYVRLSQVKRDDKVIG
YRVSPGKDSELFNSVGLQNGDIATQLNGQDLTDPAAMGNIFRSISELTELNLVVERDGQQHEVFIEF
>Mature_307_residues
MNFLELKNRAGNSPVLSRLLENGFVLQQKLSLAMCCMLIAASAWILGQLAWFIEPAEQTVVPWKATASSFSTPQSTLDIS
SLQRSNLFGAYNPTTPVVVEQQVIQDAPKTRLNLVLVGAVASSNPKRSLAVIANRGTQATYGINEEIEGTRAKLKAVLVD
RVIIDNSGRDETLMLEGIEYKRLAVSAPAPPRASSSVRGNNPASAEQKLDEIKAKIMKDPQQIFQYVRLSQVKRDDKVIG
YRVSPGKDSELFNSVGLQNGDIATQLNGQDLTDPAAMGNIFRSISELTELNLVVERDGQQHEVFIEF

Specific function: Required for secretion of cholera toxin through the outer membrane [H]

COG id: COG3031

COG function: function code U; Type II secretory pathway, component PulC

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP C family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001639 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 33657; Mature: 33657

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFLELKNRAGNSPVLSRLLENGFVLQQKLSLAMCCMLIAASAWILGQLAWFIEPAEQTV
CCHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEE
VPWKATASSFSTPQSTLDISSLQRSNLFGAYNPTTPVVVEQQVIQDAPKTRLNLVLVGAV
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHCCCCCEEEEEEEEEE
ASSNPKRSLAVIANRGTQATYGINEEIEGTRAKLKAVLVDRVIIDNSGRDETLMLEGIEY
CCCCCCCEEEEEECCCCCEECCCCCCCCHHHHHHHHHHHHHHEECCCCCCCEEEEECCCE
KRLAVSAPAPPRASSSVRGNNPASAEQKLDEIKAKIMKDPQQIFQYVRLSQVKRDDKVIG
EEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEE
YRVSPGKDSELFNSVGLQNGDIATQLNGQDLTDPAAMGNIFRSISELTELNLVVERDGQQ
EEECCCCCHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHEEEEECCCCC
HEVFIEF
CEEEEEC
>Mature Secondary Structure
MNFLELKNRAGNSPVLSRLLENGFVLQQKLSLAMCCMLIAASAWILGQLAWFIEPAEQTV
CCHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEE
VPWKATASSFSTPQSTLDISSLQRSNLFGAYNPTTPVVVEQQVIQDAPKTRLNLVLVGAV
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHCCCCCEEEEEEEEEE
ASSNPKRSLAVIANRGTQATYGINEEIEGTRAKLKAVLVDRVIIDNSGRDETLMLEGIEY
CCCCCCCEEEEEECCCCCEECCCCCCCCHHHHHHHHHHHHHHEECCCCCCCEEEEECCCE
KRLAVSAPAPPRASSSVRGNNPASAEQKLDEIKAKIMKDPQQIFQYVRLSQVKRDDKVIG
EEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEE
YRVSPGKDSELFNSVGLQNGDIATQLNGQDLTDPAAMGNIFRSISELTELNLVVERDGQQ
EEECCCCCHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHEEEEECCCCC
HEVFIEF
CEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]