| Definition | Vibrio splendidus LGP32 chromosome 1, complete genome. |
|---|---|
| Accession | NC_011753 |
| Length | 3,299,303 |
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The map label for this gene is epsD [H]
Identifier: 218708199
GI number: 218708199
Start: 129296
End: 131320
Strand: Direct
Name: epsD [H]
Synonym: VS_0135
Alternate gene names: 218708199
Gene position: 129296-131320 (Clockwise)
Preceding gene: 218708198
Following gene: 218708200
Centisome position: 3.92
GC content: 45.78
Gene sequence:
>2025_bases GTGAAGCATTGGTTTAAGAAAAGTGCATGGTTATTGGCAGGAAGCTTAATCTGCACACCCGCCGCCATCGCGAGTGATTT TAGTGCCAGCTTTAAAGGCACTGATATTCAAGAGTTTATTAATATTGTTGGCCGTAATCTAGAGAAGACGATCATCGTCG ACCCTTCGGTGCGCGGAAAAATCGATGTACGTAGCTACGACGTACTCAATGAAGAGCAATATTACAGCTTCTTCTTAAAC GTATTAGAAGTGTACGGCTATGCAGTCGTTGAAATGGACTCGGGTGTTCTTAAGATCATCAAAGCGAAAGATTCAAAAAC CTCGGCAATCCCAGTTGTTGGCGACCGTGATTCGATCACAGGCGACAGCGTTGTGACACGTGTTGTTACGGTTCGTAATG TCTCGGTTCGTGAGCTATCTCCTCTGCTTCGTCAACTGAATGACAACGCGGGCGCGGGTAACGTGGTGCACTACGATCCT GCAAATATCATCTTGATTACCGGCCGAGCGGCGGTTGTAAACCGTTTAGCTGAAATCATCAAGCGTGTAGACCAAGCTGG TGATAAAGAGATCGAAGTTGTTGAACTGAAAAATGCTTCCGCCGCGGAGATGGTGCGCATTGTCGATGCATTAAGCAAAA CCACAGATGCTAAAAACACCCCTGCTTTCCTACAGCCTAAATTAGTTGCTGATGAGCGTACCAATGCAATTCTTATCTCA GGCGACCCTAAAGTACGCAGTCGTTTAAGAAAGTTGATTGAACAGCTTGATGTGGAAATGGCGACTAAGGGTAACAACCA AGTTATCTACCTTAAATACGCAAAAGCGGAAGACTTAGTTGATGTGCTGAAAGGCGTGTCTGACAACCTGCAATCAGAGA AACAAACGTCAACCAAAGGCAGTTCATCGCAGCGCAACCAAGTGATGATTTCGGCTCACAGCGATACTAACTCATTGGTG ATTACCGCACAGCCAGACATCATGAACGCGCTGCAAGACGTGATCGCTCAACTCGATATCCGTCGTGCTCAAGTGTTGAT TGAAGCCTTAATTGTTGAAATGGCAGAAGGTGACGGCGTTAACCTAGGTGTGCAGTGGGGCAACCTAGAAACGGGAGCCA TGATTCAGTACAGCAATACCGGTGCATCGATTGGCGGTGTGATGGTGGGTCTAGAAGAAGCAAAAGATAAAACGGTTGAT CGAGTTGTAACTCCAAGTGATGGATCGAAACCCTATACGGTGAAAGAGACAGAAAAGGGTGACTATTCAACGTTAGCATC TGCTCTTTCTGGCGTTAATGGTGCAGCAATGAGTGTGGTCATGGGCGACTGGACAGCTTTGATCAGTGCGGTAGCAACCG ATTCAAACTCAAACATTCTGTCTTCTCCAAGTATCACGGTAATGGATAACGGCGAGGCTTCATTCATTGTGGGTGAAGAG GTGCCCGTTCTAACCGGTTCTACAGCAGGTTCAAGCAACGATAATCCATTCCAAACTGTTGAACGTAAAGAAGTGGGTAT TAAGCTAAAAGTCGTGCCGCAAATCAATGAAGGTGACTCGGTTCAACTGCAAATAGAACAAGAAGTATCGAACGTATTAG GGGCAAACGGGGCAGTAGATGTTCGTTTTGCTAAGCGTCAGCTAAATACGTCAGTGATTGTTCAAGATGGTCAAATGCTG GTGTTGGGTGGCCTGATTGATGAGCGCGCATTGGAGAGTGAGTCTAAGGTCCCATTCTTGGGTGATATTCCTGTTCTTGG ACACCTGTTCAAATCAACCAGTACTCAGGTTGAGAAAAAGAACCTAATGGTATTCATCAAGCCAACCATTATTCGTGATG GCATGACTGCAGATGGTATCACGCAGCGCAAATACAACTTTATTCGTGCTGAGCAACTGTACAAGGCAGAGCAAGGCTTG AAACTGATGGCTGACGATAATATCCCTGTGTTACCTAAATTTGGTGAAAGCATGAATCATCCTGCTGAAATCCAAGCCTT CATCGATCAAATGGAAGCAGAATAA
Upstream 100 bases:
>100_bases AGCTAAATCTCGTCGTCGAGAGAGATGGTCAACAACATGAAGTGTTTATTGAATTTTAAAACTTTGCGTCTAACGAAGGA CGAAAGTGTAGGAGAAGTAC
Downstream 100 bases:
>100_bases TGGCTGAATTGGTAGGGGCGGCACGTACTTATCAGCGCTTGCCGTTTAGCTTTGCGAATCGCTACAAGATGGTGTTGGAA TATCAACACCCGGAGCGCGC
Product: type II secretory pathway subunit EpsD
Products: NA
Alternate protein names: Cholera toxin secretion protein epsD [H]
Number of amino acids: Translated: 674; Mature: 674
Protein sequence:
>674_residues MKHWFKKSAWLLAGSLICTPAAIASDFSASFKGTDIQEFINIVGRNLEKTIIVDPSVRGKIDVRSYDVLNEEQYYSFFLN VLEVYGYAVVEMDSGVLKIIKAKDSKTSAIPVVGDRDSITGDSVVTRVVTVRNVSVRELSPLLRQLNDNAGAGNVVHYDP ANIILITGRAAVVNRLAEIIKRVDQAGDKEIEVVELKNASAAEMVRIVDALSKTTDAKNTPAFLQPKLVADERTNAILIS GDPKVRSRLRKLIEQLDVEMATKGNNQVIYLKYAKAEDLVDVLKGVSDNLQSEKQTSTKGSSSQRNQVMISAHSDTNSLV ITAQPDIMNALQDVIAQLDIRRAQVLIEALIVEMAEGDGVNLGVQWGNLETGAMIQYSNTGASIGGVMVGLEEAKDKTVD RVVTPSDGSKPYTVKETEKGDYSTLASALSGVNGAAMSVVMGDWTALISAVATDSNSNILSSPSITVMDNGEASFIVGEE VPVLTGSTAGSSNDNPFQTVERKEVGIKLKVVPQINEGDSVQLQIEQEVSNVLGANGAVDVRFAKRQLNTSVIVQDGQML VLGGLIDERALESESKVPFLGDIPVLGHLFKSTSTQVEKKNLMVFIKPTIIRDGMTADGITQRKYNFIRAEQLYKAEQGL KLMADDNIPVLPKFGESMNHPAEIQAFIDQMEAE
Sequences:
>Translated_674_residues MKHWFKKSAWLLAGSLICTPAAIASDFSASFKGTDIQEFINIVGRNLEKTIIVDPSVRGKIDVRSYDVLNEEQYYSFFLN VLEVYGYAVVEMDSGVLKIIKAKDSKTSAIPVVGDRDSITGDSVVTRVVTVRNVSVRELSPLLRQLNDNAGAGNVVHYDP ANIILITGRAAVVNRLAEIIKRVDQAGDKEIEVVELKNASAAEMVRIVDALSKTTDAKNTPAFLQPKLVADERTNAILIS GDPKVRSRLRKLIEQLDVEMATKGNNQVIYLKYAKAEDLVDVLKGVSDNLQSEKQTSTKGSSSQRNQVMISAHSDTNSLV ITAQPDIMNALQDVIAQLDIRRAQVLIEALIVEMAEGDGVNLGVQWGNLETGAMIQYSNTGASIGGVMVGLEEAKDKTVD RVVTPSDGSKPYTVKETEKGDYSTLASALSGVNGAAMSVVMGDWTALISAVATDSNSNILSSPSITVMDNGEASFIVGEE VPVLTGSTAGSSNDNPFQTVERKEVGIKLKVVPQINEGDSVQLQIEQEVSNVLGANGAVDVRFAKRQLNTSVIVQDGQML VLGGLIDERALESESKVPFLGDIPVLGHLFKSTSTQVEKKNLMVFIKPTIIRDGMTADGITQRKYNFIRAEQLYKAEQGL KLMADDNIPVLPKFGESMNHPAEIQAFIDQMEAE >Mature_674_residues MKHWFKKSAWLLAGSLICTPAAIASDFSASFKGTDIQEFINIVGRNLEKTIIVDPSVRGKIDVRSYDVLNEEQYYSFFLN VLEVYGYAVVEMDSGVLKIIKAKDSKTSAIPVVGDRDSITGDSVVTRVVTVRNVSVRELSPLLRQLNDNAGAGNVVHYDP ANIILITGRAAVVNRLAEIIKRVDQAGDKEIEVVELKNASAAEMVRIVDALSKTTDAKNTPAFLQPKLVADERTNAILIS GDPKVRSRLRKLIEQLDVEMATKGNNQVIYLKYAKAEDLVDVLKGVSDNLQSEKQTSTKGSSSQRNQVMISAHSDTNSLV ITAQPDIMNALQDVIAQLDIRRAQVLIEALIVEMAEGDGVNLGVQWGNLETGAMIQYSNTGASIGGVMVGLEEAKDKTVD RVVTPSDGSKPYTVKETEKGDYSTLASALSGVNGAAMSVVMGDWTALISAVATDSNSNILSSPSITVMDNGEASFIVGEE VPVLTGSTAGSSNDNPFQTVERKEVGIKLKVVPQINEGDSVQLQIEQEVSNVLGANGAVDVRFAKRQLNTSVIVQDGQML VLGGLIDERALESESKVPFLGDIPVLGHLFKSTSTQVEKKNLMVFIKPTIIRDGMTADGITQRKYNFIRAEQLYKAEQGL KLMADDNIPVLPKFGESMNHPAEIQAFIDQMEAE
Specific function: Required for secretion of cholera toxin through the outer membrane [H]
COG id: COG1450
COG function: function code NU; Type II secretory pathway, component PulD
Gene ontology:
Cell location: Cell outer membrane; Peripheral membrane protein (Potential) [H]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the GSP D family [H]
Homologues:
Organism=Escherichia coli, GI87082242, Length=667, Percent_Identity=44.0779610194903, Blast_Score=532, Evalue=1e-152, Organism=Escherichia coli, GI1789793, Length=373, Percent_Identity=26.5415549597855, Blast_Score=85, Evalue=2e-17,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001775 - InterPro: IPR005644 - InterPro: IPR004846 - InterPro: IPR013356 - InterPro: IPR004845 - InterPro: IPR001814 [H]
Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N [H]
EC number: NA
Molecular weight: Translated: 73034; Mature: 73034
Theoretical pI: Translated: 4.73; Mature: 4.73
Prosite motif: PS00875 T2SP_D
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.1 %Cys (Translated Protein) 2.7 %Met (Translated Protein) 2.8 %Cys+Met (Translated Protein) 0.1 %Cys (Mature Protein) 2.7 %Met (Mature Protein) 2.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKHWFKKSAWLLAGSLICTPAAIASDFSASFKGTDIQEFINIVGRNLEKTIIVDPSVRGK CCCHHHCCHHHHCCHHHHCCHHHHHCCCCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCE IDVRSYDVLNEEQYYSFFLNVLEVYGYAVVEMDSGVLKIIKAKDSKTSAIPVVGDRDSIT EEEEEECCCCHHHHHHHHHHHHHHHCEEEEEECCCEEEEEEECCCCCCEEEEECCCCCCC GDSVVTRVVTVRNVSVRELSPLLRQLNDNAGAGNVVHYDPANIILITGRAAVVNRLAEII CHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCEEEEECCHHHHHHHHHHH KRVDQAGDKEIEVVELKNASAAEMVRIVDALSKTTDAKNTPAFLQPKLVADERTNAILIS HHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCEEEEE GDPKVRSRLRKLIEQLDVEMATKGNNQVIYLKYAKAEDLVDVLKGVSDNLQSEKQTSTKG CCHHHHHHHHHHHHHHCCEEECCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCC SSSQRNQVMISAHSDTNSLVITAQPDIMNALQDVIAQLDIRRAQVLIEALIVEMAEGDGV CCCCCCEEEEEEECCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC NLGVQWGNLETGAMIQYSNTGASIGGVMVGLEEAKDKTVDRVVTPSDGSKPYTVKETEKG EEEEEECCCCCCEEEEECCCCCCCCCEEEEHHHHCCCCCCEEECCCCCCCCEEEECCCCC DYSTLASALSGVNGAAMSVVMGDWTALISAVATDSNSNILSSPSITVMDNGEASFIVGEE CHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHCCCCCCEECCCCEEEEECCCEEEEECCC VPVLTGSTAGSSNDNPFQTVERKEVGIKLKVVPQINEGDSVQLQIEQEVSNVLGANGAVD CCEEECCCCCCCCCCCHHHHHHHHCCEEEEEEECCCCCCCEEEEEHHHHHHHHCCCCCEE VRFAKRQLNTSVIVQDGQMLVLGGLIDERALESESKVPFLGDIPVLGHLFKSTSTQVEKK EEEHHHHCCCEEEEECCCEEEEECCHHHHHHCCCCCCCEECCCHHHHHHHHCCCCCEECC NLMVFIKPTIIRDGMTADGITQRKYNFIRAEQLYKAEQGLKLMADDNIPVLPKFGESMNH CEEEEEECEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCC PAEIQAFIDQMEAE CHHHHHHHHHHCCC >Mature Secondary Structure MKHWFKKSAWLLAGSLICTPAAIASDFSASFKGTDIQEFINIVGRNLEKTIIVDPSVRGK CCCHHHCCHHHHCCHHHHCCHHHHHCCCCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCE IDVRSYDVLNEEQYYSFFLNVLEVYGYAVVEMDSGVLKIIKAKDSKTSAIPVVGDRDSIT EEEEEECCCCHHHHHHHHHHHHHHHCEEEEEECCCEEEEEEECCCCCCEEEEECCCCCCC GDSVVTRVVTVRNVSVRELSPLLRQLNDNAGAGNVVHYDPANIILITGRAAVVNRLAEII CHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCEEEEECCHHHHHHHHHHH KRVDQAGDKEIEVVELKNASAAEMVRIVDALSKTTDAKNTPAFLQPKLVADERTNAILIS HHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCEEEEE GDPKVRSRLRKLIEQLDVEMATKGNNQVIYLKYAKAEDLVDVLKGVSDNLQSEKQTSTKG CCHHHHHHHHHHHHHHCCEEECCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCC SSSQRNQVMISAHSDTNSLVITAQPDIMNALQDVIAQLDIRRAQVLIEALIVEMAEGDGV CCCCCCEEEEEEECCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC NLGVQWGNLETGAMIQYSNTGASIGGVMVGLEEAKDKTVDRVVTPSDGSKPYTVKETEKG EEEEEECCCCCCEEEEECCCCCCCCCEEEEHHHHCCCCCCEEECCCCCCCCEEEECCCCC DYSTLASALSGVNGAAMSVVMGDWTALISAVATDSNSNILSSPSITVMDNGEASFIVGEE CHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHCCCCCCEECCCCEEEEECCCEEEEECCC VPVLTGSTAGSSNDNPFQTVERKEVGIKLKVVPQINEGDSVQLQIEQEVSNVLGANGAVD CCEEECCCCCCCCCCCHHHHHHHHCCEEEEEEECCCCCCCEEEEEHHHHHHHHCCCCCEE VRFAKRQLNTSVIVQDGQMLVLGGLIDERALESESKVPFLGDIPVLGHLFKSTSTQVEKK EEEHHHHCCCEEEEECCCEEEEECCHHHHHHCCCCCCCEECCCHHHHHHHHCCCCCEECC NLMVFIKPTIIRDGMTADGITQRKYNFIRAEQLYKAEQGLKLMADDNIPVLPKFGESMNH CEEEEEECEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCC PAEIQAFIDQMEAE CHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 10952301 [H]