Click here to switch to the map view.

The map label for this gene is ibpA [H]

Identifier: 218708102

GI number: 218708102

Start: 14195

End: 14629

Strand: Direct

Name: ibpA [H]

Synonym: VS_0014

Alternate gene names: 218708102

Gene position: 14195-14629 (Clockwise)

Preceding gene: 218708101

Following gene: 218708104

Centisome position: 0.43

GC content: 43.91

Gene sequence:

>435_bases
ATGAGAACTGTAGATTTCACTCCACTTTACCGCAACGCAATCGGCTTCGATCGTCTATTCAACATGATGGAAGCGAACAC
ATCGAAGAACTCTTCTGGCGGTTACCCTCCATACAACATCGAGCAAAAAGACGAGAACAACTACCGTATTACTATGGCCG
TTGCTGGTTTTGCTGATGACCAATTAGATCTTACTCAGAAAGAGAACATGCTAATTGTTAAAGGTGAGCGTAAAGCAGAA
GCAGAGAAAACCTTCGTATACCAAGGTATCGCAGAGCGTGATTTCGAGCGTAAATTCCAACTGGCTGACTACGTAAAAGT
GGTGGGCGCAAGCATGGAAAATGGTCTTCTTCACATCGACCTAGAACGCGAAATCCCAGAAGCGATGCAACCACGTAAGA
TTGCTATTAATGGTAATAGTCTTCTAGAAGGCTAA

Upstream 100 bases:

>100_bases
GAATGCGAATTGAATCCCTTAGCTGTTTACTGAATAATTCACAGGTTCGATCTCAGTAAAAATTACAGCTAAGACTATTG
CTTACTAAAAGGATAGCATT

Downstream 100 bases:

>100_bases
AGCTATTGGCTTAGCTCAATTGAGTTAAAGCGAATCGGGAAGTAAAAGTGAAAGAGCACCAGTACCTTGAAAAAGGTAGG
TGCTCTTTTTTGTTTGTCCT

Product: small heat shock protein IbpA

Products: NA

Alternate protein names: 16 kDa heat shock protein A [H]

Number of amino acids: Translated: 144; Mature: 144

Protein sequence:

>144_residues
MRTVDFTPLYRNAIGFDRLFNMMEANTSKNSSGGYPPYNIEQKDENNYRITMAVAGFADDQLDLTQKENMLIVKGERKAE
AEKTFVYQGIAERDFERKFQLADYVKVVGASMENGLLHIDLEREIPEAMQPRKIAINGNSLLEG

Sequences:

>Translated_144_residues
MRTVDFTPLYRNAIGFDRLFNMMEANTSKNSSGGYPPYNIEQKDENNYRITMAVAGFADDQLDLTQKENMLIVKGERKAE
AEKTFVYQGIAERDFERKFQLADYVKVVGASMENGLLHIDLEREIPEAMQPRKIAINGNSLLEG
>Mature_144_residues
MRTVDFTPLYRNAIGFDRLFNMMEANTSKNSSGGYPPYNIEQKDENNYRITMAVAGFADDQLDLTQKENMLIVKGERKAE
AEKTFVYQGIAERDFERKFQLADYVKVVGASMENGLLHIDLEREIPEAMQPRKIAINGNSLLEG

Specific function: Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently ref

COG id: COG0071

COG function: function code O; Molecular chaperone (small heat shock protein)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small heat shock protein (HSP20) family [H]

Homologues:

Organism=Escherichia coli, GI1790122, Length=138, Percent_Identity=62.3188405797101, Blast_Score=179, Evalue=5e-47,
Organism=Escherichia coli, GI87082316, Length=138, Percent_Identity=42.7536231884058, Blast_Score=115, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002068
- InterPro:   IPR008978 [H]

Pfam domain/function: PF00011 HSP20 [H]

EC number: NA

Molecular weight: Translated: 16418; Mature: 16418

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS01031 HSP20

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTVDFTPLYRNAIGFDRLFNMMEANTSKNSSGGYPPYNIEQKDENNYRITMAVAGFADD
CCCCCCCHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCC
QLDLTQKENMLIVKGERKAEAEKTFVYQGIAERDFERKFQLADYVKVVGASMENGLLHID
CCCCCCCCCEEEEECCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
LEREIPEAMQPRKIAINGNSLLEG
ECCCCHHHCCCCEEEECCCCCCCC
>Mature Secondary Structure
MRTVDFTPLYRNAIGFDRLFNMMEANTSKNSSGGYPPYNIEQKDENNYRITMAVAGFADD
CCCCCCCHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCC
QLDLTQKENMLIVKGERKAEAEKTFVYQGIAERDFERKFQLADYVKVVGASMENGLLHID
CCCCCCCCCEEEEECCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
LEREIPEAMQPRKIAINGNSLLEG
ECCCCHHHCCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA