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The map label for this gene is oxaA

Identifier: 218708091

GI number: 218708091

Start: 2343

End: 3962

Strand: Reverse

Name: oxaA

Synonym: VS_0003

Alternate gene names: 218708091

Gene position: 3962-2343 (Counterclockwise)

Preceding gene: 218708092

Following gene: 218708090

Centisome position: 0.12

GC content: 46.23

Gene sequence:

>1620_bases
ATGGATTCTCAACGTAATATCCTGTTAATCGCATTGGCTTTGGTTTCTTTCCTACTGTTCCAACAATGGAACGTAGCTCA
GAACCCAGCTCCACAAGCGGTTGAGCAGGCACAATCTGGCAGCACCCTACCAGCGCCATCTTATGCAGATGATCTAGACC
CGGCTCCTGGTCAAGTTGCTTCTGCTAAAACTATCACAGTAACAACTGATGTTCTGACTCTGTCAATTGATACGGTTGGT
GGTGATGTCGTTACAGCAAACCTAAACGATTACTCTGCTGAGTTCGATTCTGAAGATACTTTTGTTCTTCTTAAAAACGA
GCCTGGTCACCAATTTATCGCTCAAAGCGGTCTAGTGGGTCCTCAAGGTATCGATTTAAGCAGCACTAACCGCCCTAGCT
ACACGGTTTCAGCAGACAGCTTCACGTTGGCTGAAGGTCAAGATGAACTACGCATCCCAATGACTTACCAAGCGAACGGC
CTGGATTACACAAAAACATTCGTCCTTAAGCGCGGCAGCTACGCGATTGACGTTGAATACGATGTAGTCAACAACTCTGG
CAATAACGCAACATTCGGCATGTACGCTCACCTACGTCAAAACGTTATGGATGACGGTGGTAGCCTAACAATGCCAACTT
ACCGTGGTGGTGCTTACTCTACGGAAGATACGCGTTACAAAAAATACAGCTTCGACGACATGCAAGATCGCAACCTTTCT
CTTAACCTAGCAAACGGTCAAGGTTGGGCAGCGATGATTCAACACTACTTTGCAAGTGCTTGGATTCCACGCGACGAAGC
AGGCAGCAACCTTTACACTCGTGTAATTGGTAACCTTGGCGACATCGGTGTTCGCATGCCGAACAAAACCATCGCTACTG
GCGACGAAGCAAGCTTCAAAGCAACGCTTTGGGTTGGTCCTAAACTTCAAGACCAAATGGCTGCTGTTGCACCAAACCTA
GACCTAGTAGTTGACTACGGTTGGTTATGGTTCATTGCTAAACCACTTCATACTCTGCTTTCATTTATTCAAGGCATCGT
TGTGAACTGGGGTCTGGCAATCATCTGTCTAACTTTCATCGTTCGTGGTGCTATGTACCCACTAACGAAAGCTCAGTACA
CGTCTATGGCGAAAATGCGCATGCTTCAGCCTAAGCTGACTGCAATGCGTGAGCGTATTGGCGACGACCGTCAACGCATG
AGTCAAGAAATGATGGAGCTTTACAAGAAAGAGAAAGTAAACCCACTAGGTGGCTGTTTACCTATCCTTCTTCAAATGCC
TATCTTCATTTCGCTATACTGGGCACTAATGGAGTCTGTTGAACTGCGTCACTCACCGTTCTTCGGTTGGATTACTGACC
TTTCAGCACAAGACCCATACTACATCTTGCCACTTCTGATGGGTGCTTCAATGTTCCTAATCCAGAAGATGAGCCCGACA
ACTGTAACGGATCCAATGCAGCAGAAGATCATGACCTTTATGCCGGTTATGTTCACATTCTTCTTCCTGTTCTTCCCTTC
AGGTCTGGTTCTTTACTGGCTAGTATCGAACATCGTAACTCTAATTCAGCAAACGCTTATCTACCGCGCACTGGAAAAGA
AAGGCTTACATTCTAAGTAA

Upstream 100 bases:

>100_bases
GTTGGTTATCAGGCAAACGTCTATTAAAATGCCATCCTTTGAACGAAGGGGGCTTTGACCCCGTTCCACCAGTCCAAAAA
CAAGACAGAGATAAATAACG

Downstream 100 bases:

>100_bases
GTTCGATAATAGAAAGAGATAAAGAAAGGCGACCAAAAGGTCGCCTTTTTGTTTTTAGCTGATTACAATTCAGCTAATTG
ATTAATCGTGAATGCCCTCT

Product: putative inner membrane protein translocase component YidC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 539; Mature: 539

Protein sequence:

>539_residues
MDSQRNILLIALALVSFLLFQQWNVAQNPAPQAVEQAQSGSTLPAPSYADDLDPAPGQVASAKTITVTTDVLTLSIDTVG
GDVVTANLNDYSAEFDSEDTFVLLKNEPGHQFIAQSGLVGPQGIDLSSTNRPSYTVSADSFTLAEGQDELRIPMTYQANG
LDYTKTFVLKRGSYAIDVEYDVVNNSGNNATFGMYAHLRQNVMDDGGSLTMPTYRGGAYSTEDTRYKKYSFDDMQDRNLS
LNLANGQGWAAMIQHYFASAWIPRDEAGSNLYTRVIGNLGDIGVRMPNKTIATGDEASFKATLWVGPKLQDQMAAVAPNL
DLVVDYGWLWFIAKPLHTLLSFIQGIVVNWGLAIICLTFIVRGAMYPLTKAQYTSMAKMRMLQPKLTAMRERIGDDRQRM
SQEMMELYKKEKVNPLGGCLPILLQMPIFISLYWALMESVELRHSPFFGWITDLSAQDPYYILPLLMGASMFLIQKMSPT
TVTDPMQQKIMTFMPVMFTFFFLFFPSGLVLYWLVSNIVTLIQQTLIYRALEKKGLHSK

Sequences:

>Translated_539_residues
MDSQRNILLIALALVSFLLFQQWNVAQNPAPQAVEQAQSGSTLPAPSYADDLDPAPGQVASAKTITVTTDVLTLSIDTVG
GDVVTANLNDYSAEFDSEDTFVLLKNEPGHQFIAQSGLVGPQGIDLSSTNRPSYTVSADSFTLAEGQDELRIPMTYQANG
LDYTKTFVLKRGSYAIDVEYDVVNNSGNNATFGMYAHLRQNVMDDGGSLTMPTYRGGAYSTEDTRYKKYSFDDMQDRNLS
LNLANGQGWAAMIQHYFASAWIPRDEAGSNLYTRVIGNLGDIGVRMPNKTIATGDEASFKATLWVGPKLQDQMAAVAPNL
DLVVDYGWLWFIAKPLHTLLSFIQGIVVNWGLAIICLTFIVRGAMYPLTKAQYTSMAKMRMLQPKLTAMRERIGDDRQRM
SQEMMELYKKEKVNPLGGCLPILLQMPIFISLYWALMESVELRHSPFFGWITDLSAQDPYYILPLLMGASMFLIQKMSPT
TVTDPMQQKIMTFMPVMFTFFFLFFPSGLVLYWLVSNIVTLIQQTLIYRALEKKGLHSK
>Mature_539_residues
MDSQRNILLIALALVSFLLFQQWNVAQNPAPQAVEQAQSGSTLPAPSYADDLDPAPGQVASAKTITVTTDVLTLSIDTVG
GDVVTANLNDYSAEFDSEDTFVLLKNEPGHQFIAQSGLVGPQGIDLSSTNRPSYTVSADSFTLAEGQDELRIPMTYQANG
LDYTKTFVLKRGSYAIDVEYDVVNNSGNNATFGMYAHLRQNVMDDGGSLTMPTYRGGAYSTEDTRYKKYSFDDMQDRNLS
LNLANGQGWAAMIQHYFASAWIPRDEAGSNLYTRVIGNLGDIGVRMPNKTIATGDEASFKATLWVGPKLQDQMAAVAPNL
DLVVDYGWLWFIAKPLHTLLSFIQGIVVNWGLAIICLTFIVRGAMYPLTKAQYTSMAKMRMLQPKLTAMRERIGDDRQRM
SQEMMELYKKEKVNPLGGCLPILLQMPIFISLYWALMESVELRHSPFFGWITDLSAQDPYYILPLLMGASMFLIQKMSPT
TVTDPMQQKIMTFMPVMFTFFFLFFPSGLVLYWLVSNIVTLIQQTLIYRALEKKGLHSK

Specific function: Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and indepe

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 1 subfamily

Homologues:

Organism=Homo sapiens, GI223718097, Length=209, Percent_Identity=26.7942583732057, Blast_Score=68, Evalue=3e-11,
Organism=Escherichia coli, GI1790140, Length=548, Percent_Identity=58.029197080292, Blast_Score=607, Evalue=1e-175,
Organism=Drosophila melanogaster, GI24662345, Length=219, Percent_Identity=30.1369863013699, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI21356443, Length=219, Percent_Identity=30.1369863013699, Blast_Score=82, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OXAA_VIBSL (B7VGH7)

Other databases:

- EMBL:   FM954972
- RefSeq:   YP_002415712.1
- ProteinModelPortal:   B7VGH7
- SMR:   B7VGH7
- GeneID:   7159701
- GenomeReviews:   FM954972_GR
- KEGG:   vsp:VS_0003
- HOGENOM:   HBG507812
- OMA:   TYRGAAF
- ProtClustDB:   PRK01318
- HAMAP:   MF_01810
- InterPro:   IPR019998
- InterPro:   IPR001708
- PANTHER:   PTHR12428
- PRINTS:   PR00701
- PRINTS:   PR01900
- TIGRFAMs:   TIGR03593
- TIGRFAMs:   TIGR03592

Pfam domain/function: PF02096 60KD_IMP

EC number: NA

Molecular weight: Translated: 60163; Mature: 60163

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x15a2e2b4)-; HASH(0x18925730)-; HASH(0x192c14a4)-; HASH(0x1892594c)-; HASH(0x192147f4)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSQRNILLIALALVSFLLFQQWNVAQNPAPQAVEQAQSGSTLPAPSYADDLDPAPGQVA
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
SAKTITVTTDVLTLSIDTVGGDVVTANLNDYSAEFDSEDTFVLLKNEPGHQFIAQSGLVG
CCEEEEEEEEEEEEEEEECCCCEEEECCCCCCCCCCCCCCEEEEECCCCHHHHHHCCCCC
PQGIDLSSTNRPSYTVSADSFTLAEGQDELRIPMTYQANGLDYTKTFVLKRGSYAIDVEY
CCCCCCCCCCCCCEEEECCCEEEECCCCCEEEEEEEECCCCCHHHHEEEECCCEEEEEEE
DVVNNSGNNATFGMYAHLRQNVMDDGGSLTMPTYRGGAYSTEDTRYKKYSFDDMQDRNLS
EEEECCCCCCEEHHHHHHHHHHHCCCCCEECCEECCCCCCCCCCCEEECCCCCCCCCCEE
LNLANGQGWAAMIQHYFASAWIPRDEAGSNLYTRVIGNLGDIGVRMPNKTIATGDEASFK
EEECCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCEECCCCCEECCCCCCEE
ATLWVGPKLQDQMAAVAPNLDLVVDYGWLWFIAKPLHTLLSFIQGIVVNWGLAIICLTFI
EEEEECCCHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VRGAMYPLTKAQYTSMAKMRMLQPKLTAMRERIGDDRQRMSQEMMELYKKEKVNPLGGCL
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHH
PILLQMPIFISLYWALMESVELRHSPFFGWITDLSAQDPYYILPLLMGASMFLIQKMSPT
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHCCHHHHHCCCCCC
TVTDPMQQKIMTFMPVMFTFFFLFFPSGLVLYWLVSNIVTLIQQTLIYRALEKKGLHSK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
>Mature Secondary Structure
MDSQRNILLIALALVSFLLFQQWNVAQNPAPQAVEQAQSGSTLPAPSYADDLDPAPGQVA
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
SAKTITVTTDVLTLSIDTVGGDVVTANLNDYSAEFDSEDTFVLLKNEPGHQFIAQSGLVG
CCEEEEEEEEEEEEEEEECCCCEEEECCCCCCCCCCCCCCEEEEECCCCHHHHHHCCCCC
PQGIDLSSTNRPSYTVSADSFTLAEGQDELRIPMTYQANGLDYTKTFVLKRGSYAIDVEY
CCCCCCCCCCCCCEEEECCCEEEECCCCCEEEEEEEECCCCCHHHHEEEECCCEEEEEEE
DVVNNSGNNATFGMYAHLRQNVMDDGGSLTMPTYRGGAYSTEDTRYKKYSFDDMQDRNLS
EEEECCCCCCEEHHHHHHHHHHHCCCCCEECCEECCCCCCCCCCCEEECCCCCCCCCCEE
LNLANGQGWAAMIQHYFASAWIPRDEAGSNLYTRVIGNLGDIGVRMPNKTIATGDEASFK
EEECCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCEECCCCCEECCCCCCEE
ATLWVGPKLQDQMAAVAPNLDLVVDYGWLWFIAKPLHTLLSFIQGIVVNWGLAIICLTFI
EEEEECCCHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VRGAMYPLTKAQYTSMAKMRMLQPKLTAMRERIGDDRQRMSQEMMELYKKEKVNPLGGCL
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHH
PILLQMPIFISLYWALMESVELRHSPFFGWITDLSAQDPYYILPLLMGASMFLIQKMSPT
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHCCHHHHHCCCCCC
TVTDPMQQKIMTFMPVMFTFFFLFFPSGLVLYWLVSNIVTLIQQTLIYRALEKKGLHSK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA