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The map label for this gene is iolS [H]

Identifier: 218704987

GI number: 218704987

Start: 1796438

End: 1797385

Strand: Reverse

Name: iolS [H]

Synonym: ECUMN_1771

Alternate gene names: 218704987

Gene position: 1797385-1796438 (Counterclockwise)

Preceding gene: 218704988

Following gene: 218704986

Centisome position: 34.55

GC content: 52.64

Gene sequence:

>948_bases
ATGAAAACACTACCTCCAGTCGCACTAGGTACATGGTCCTGGGGCACAGGCTTTGCCGGCGGCGACACCGTCTTTGGTAA
TCATCTTTCTGATACTCAGATGGCAGAAGTGTTCACTGCGGCCATGAGTAAGGGCCTCAATCTCTGGGATACCGCAGCAG
TATATGGTATGGGGAGTTCCGAGACTGCGCTGGGAGCATTAGTCCGTCAGTTTCCCCGCGAGAACATAATTTTATCCACC
AAATTCACGCCGCAGATTGCGGACAAGCAGTCTGCGCAGCCTGTCAGCGATATGCTTGAGGCCAGCCTTGGGCGCCTGGG
CGTGGACGCGATTGATATCTACTGGATCCATAATCCCCTCGACGTCGAAAAATGGACACCAGGACTGATCCCACTTTTAC
AAAGCGGTAAGGTAAAACGCGTAGGTGTTTCCAACCACAATCTGGCACAAATCAGACGCGCCAATGAAATCCTTAACGCT
TCCGGTTATTCCCTCAGTGCAGTACAAAATCACTACAGCCTGCTCTATCGCGCTTCTGAAGAGGCCGGGATCCTTGATTA
TTGCCGACAAAATAACATCACGTTCTTTGCTTACATGGTCCTGGAGCAAGGCGCGCTCAGTGGTCGTTATGATTCAAATC
ATCCCATGCCTGCCGGGAGTGGCCGGGCCGAAAGTTATAACGCAGTACTGCCGCAGATAGAAAGACTAACCGCCGCCATG
AAAAAAATGGGAGCCGAAAGGAATGCCAGCGTGGCACAGATAGCCATCGCATGGGCTATTGCGAAAGGTACCCTTCCCCT
CGTTGGTGCGACTAAAGTCCATCACGTTCTGGACGCCGCCTGCGCTTCAGACATCCAGTTACGCGATGAGGAAATCATCC
TGCTGGAACAACTCGCCGCAGAGACCAGAGTGGATACACGAGGCGCCTGGGAAAAACCGATGGTGTAA

Upstream 100 bases:

>100_bases
TTAAATGCACTCCGCCGGACAGCTTAATTAATTCATCGTTACTCACCTTACTTGGCCGGTTTAAGTCAGCCACGATCCGG
CCTTTTTTCAGGAGCTGAAT

Downstream 100 bases:

>100_bases
AGCCCGTCCGGAACAGACTGTCATGAATGACACACACGAACGGGCTGTTCCGGGTGATTCTAATCTGTATCACTTTTACT
GCTTTGTATGAATGGTGAGA

Product: putative Tas protein

Products: NA

Alternate protein names: AKR11A; Vegetative protein 147; VEG147 [H]

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MKTLPPVALGTWSWGTGFAGGDTVFGNHLSDTQMAEVFTAAMSKGLNLWDTAAVYGMGSSETALGALVRQFPRENIILST
KFTPQIADKQSAQPVSDMLEASLGRLGVDAIDIYWIHNPLDVEKWTPGLIPLLQSGKVKRVGVSNHNLAQIRRANEILNA
SGYSLSAVQNHYSLLYRASEEAGILDYCRQNNITFFAYMVLEQGALSGRYDSNHPMPAGSGRAESYNAVLPQIERLTAAM
KKMGAERNASVAQIAIAWAIAKGTLPLVGATKVHHVLDAACASDIQLRDEEIILLEQLAAETRVDTRGAWEKPMV

Sequences:

>Translated_315_residues
MKTLPPVALGTWSWGTGFAGGDTVFGNHLSDTQMAEVFTAAMSKGLNLWDTAAVYGMGSSETALGALVRQFPRENIILST
KFTPQIADKQSAQPVSDMLEASLGRLGVDAIDIYWIHNPLDVEKWTPGLIPLLQSGKVKRVGVSNHNLAQIRRANEILNA
SGYSLSAVQNHYSLLYRASEEAGILDYCRQNNITFFAYMVLEQGALSGRYDSNHPMPAGSGRAESYNAVLPQIERLTAAM
KKMGAERNASVAQIAIAWAIAKGTLPLVGATKVHHVLDAACASDIQLRDEEIILLEQLAAETRVDTRGAWEKPMV
>Mature_315_residues
MKTLPPVALGTWSWGTGFAGGDTVFGNHLSDTQMAEVFTAAMSKGLNLWDTAAVYGMGSSETALGALVRQFPRENIILST
KFTPQIADKQSAQPVSDMLEASLGRLGVDAIDIYWIHNPLDVEKWTPGLIPLLQSGKVKRVGVSNHNLAQIRRANEILNA
SGYSLSAVQNHYSLLYRASEEAGILDYCRQNNITFFAYMVLEQGALSGRYDSNHPMPAGSGRAESYNAVLPQIERLTAAM
KKMGAERNASVAQIAIAWAIAKGTLPLVGATKVHHVLDAACASDIQLRDEEIILLEQLAAETRVDTRGAWEKPMV

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI4504825, Length=294, Percent_Identity=23.8095238095238, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI27436969, Length=294, Percent_Identity=23.8095238095238, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI223718702, Length=208, Percent_Identity=28.8461538461538, Blast_Score=72, Evalue=7e-13,
Organism=Escherichia coli, GI87081735, Length=297, Percent_Identity=29.2929292929293, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1788070, Length=328, Percent_Identity=30.7926829268293, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1789375, Length=329, Percent_Identity=25.8358662613982, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788081, Length=298, Percent_Identity=27.8523489932886, Blast_Score=80, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320079, Length=288, Percent_Identity=25.3472222222222, Blast_Score=80, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6325169, Length=329, Percent_Identity=21.580547112462, Blast_Score=76, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6323998, Length=319, Percent_Identity=26.9592476489028, Blast_Score=70, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6319958, Length=295, Percent_Identity=26.7796610169492, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR018170
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 34184; Mature: 34184

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLPPVALGTWSWGTGFAGGDTVFGNHLSDTQMAEVFTAAMSKGLNLWDTAAVYGMGSS
CCCCCCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHCCCCCC
ETALGALVRQFPRENIILSTKFTPQIADKQSAQPVSDMLEASLGRLGVDAIDIYWIHNPL
HHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCC
DVEKWTPGLIPLLQSGKVKRVGVSNHNLAQIRRANEILNASGYSLSAVQNHYSLLYRASE
CCCCCCCCHHHHHCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHEECCC
EAGILDYCRQNNITFFAYMVLEQGALSGRYDSNHPMPAGSGRAESYNAVLPQIERLTAAM
CCCHHHHHHCCCCEEEEEEEHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
KKMGAERNASVAQIAIAWAIAKGTLPLVGATKVHHVLDAACASDIQLRDEEIILLEQLAA
HHHCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEECCCHHHHHHHHHH
ETRVDTRGAWEKPMV
HHCCCCCCCCCCCCC
>Mature Secondary Structure
MKTLPPVALGTWSWGTGFAGGDTVFGNHLSDTQMAEVFTAAMSKGLNLWDTAAVYGMGSS
CCCCCCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHCCCCCC
ETALGALVRQFPRENIILSTKFTPQIADKQSAQPVSDMLEASLGRLGVDAIDIYWIHNPL
HHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCC
DVEKWTPGLIPLLQSGKVKRVGVSNHNLAQIRRANEILNASGYSLSAVQNHYSLLYRASE
CCCCCCCCHHHHHCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHEECCC
EAGILDYCRQNNITFFAYMVLEQGALSGRYDSNHPMPAGSGRAESYNAVLPQIERLTAAM
CCCHHHHHHCCCCEEEEEEEHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
KKMGAERNASVAQIAIAWAIAKGTLPLVGATKVHHVLDAACASDIQLRDEEIILLEQLAA
HHHCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEECCCHHHHHHHHHH
ETRVDTRGAWEKPMV
HHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584049; 9384377; 9298659 [H]