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The map label for this gene is ycgE [H]

Identifier: 218704675

GI number: 218704675

Start: 1459593

End: 1460324

Strand: Reverse

Name: ycgE [H]

Synonym: ECUMN_1447

Alternate gene names: 218704675

Gene position: 1460324-1459593 (Counterclockwise)

Preceding gene: 218704676

Following gene: 218704674

Centisome position: 28.07

GC content: 48.91

Gene sequence:

>732_bases
GTGGCTTATTACAGCATTGGTGATGTTGCCGAACGTTGCGGGATTAATCCTGTCACTCTCCGGGCCTGGCAACGCCGCTA
CGGTTTGTTAAAACCACAGCGCAGTGAAGGCGGACACCGACTCTTTGATGAAGAAGACATACAACGCATCGAAGAGATCA
AGCGTTGGATAAGTAATGGCGTCCCTGTAGGCAAAGTTAAAGCATTACTGGAAACCACCAGCCAGGATACGGAAGATGAC
TGGAGCCGCCTGCAAGAAGAGATGATGTCAATTCTTCGTATGGCTAATCCTGCCAAACTACGCGCGAGAATTATTTCACT
GGGTCGAGAGTACCCAGTAGATCAATTGATTAATCATGTTTACCTTCCTGTTCGCCAGCGTCTCGTGCTTGATCACAACA
CCTCCCGCATTATGAGCAGTATGTTTGACGGCGCATTAATTGAATACGCAGCAGCCTCGCTTTTCGAAATGCGCCGTAAG
CCCGGTAAAGAAGCCATTCTGATGGCGTGGAATGTTGAAGAGAGAGCACGATTGTGGCTGGAAGCATGGCGTTTATCATT
GTCAGGATGGCACATTTCTGTTCTTGCTGATCCCATTGAAGCGCCGCGCCCGGAACTGTTCCCAACGCAAACATTGATTG
TCTGGACAGGCATGGCACCAACGAGAAGGCAAAACGAACTTTTACAACACTGGGGTGAGCAAGGTTATAAAGTCATCTTT
CATGCCCCCTAA

Upstream 100 bases:

>100_bases
TGAAATCTTATTTATACTTTGTACAATTTTAGCGTATATTGTACAAAGTATTATTGGGTCGTGTACAGGCGACGGAGATT
TATGACCGCAAGGAGGAAGT

Downstream 100 bases:

>100_bases
TTTCACCTTTATCCCGCCCCTTAGACAGAATCTTATAATCTGAACCCACAATAGCGTTTGTACCGGAGCTGGTCCGTTGC
AAAATGCTCACCGGGAGAAT

Product: putative DNA-binding transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 242

Protein sequence:

>243_residues
MAYYSIGDVAERCGINPVTLRAWQRRYGLLKPQRSEGGHRLFDEEDIQRIEEIKRWISNGVPVGKVKALLETTSQDTEDD
WSRLQEEMMSILRMANPAKLRARIISLGREYPVDQLINHVYLPVRQRLVLDHNTSRIMSSMFDGALIEYAAASLFEMRRK
PGKEAILMAWNVEERARLWLEAWRLSLSGWHISVLADPIEAPRPELFPTQTLIVWTGMAPTRRQNELLQHWGEQGYKVIF
HAP

Sequences:

>Translated_243_residues
MAYYSIGDVAERCGINPVTLRAWQRRYGLLKPQRSEGGHRLFDEEDIQRIEEIKRWISNGVPVGKVKALLETTSQDTEDD
WSRLQEEMMSILRMANPAKLRARIISLGREYPVDQLINHVYLPVRQRLVLDHNTSRIMSSMFDGALIEYAAASLFEMRRK
PGKEAILMAWNVEERARLWLEAWRLSLSGWHISVLADPIEAPRPELFPTQTLIVWTGMAPTRRQNELLQHWGEQGYKVIF
HAP
>Mature_242_residues
AYYSIGDVAERCGINPVTLRAWQRRYGLLKPQRSEGGHRLFDEEDIQRIEEIKRWISNGVPVGKVKALLETTSQDTEDDW
SRLQEEMMSILRMANPAKLRARIISLGREYPVDQLINHVYLPVRQRLVLDHNTSRIMSSMFDGALIEYAAASLFEMRRKP
GKEAILMAWNVEERARLWLEAWRLSLSGWHISVLADPIEAPRPELFPTQTLIVWTGMAPTRRQNELLQHWGEQGYKVIFH
AP

Specific function: Controls the expression of 6 small proteins that may play a role in biofilm maturation. Binds to and represses the operator of the ycgZ-ymgA-ariR-ymgC operon, it also regulates yliL and ynaK. Binding is antagonized by YcgF upon blue-light (470 nm) irradia

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787409, Length=243, Percent_Identity=99.1769547325103, Blast_Score=496, Evalue=1e-142,
Organism=Escherichia coli, GI1788448, Length=239, Percent_Identity=48.5355648535565, Blast_Score=241, Evalue=2e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551 [H]

Pfam domain/function: PF00376 MerR [H]

EC number: NA

Molecular weight: Translated: 28219; Mature: 28088

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYYSIGDVAERCGINPVTLRAWQRRYGLLKPQRSEGGHRLFDEEDIQRIEEIKRWISNG
CCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
VPVGKVKALLETTSQDTEDDWSRLQEEMMSILRMANPAKLRARIISLGREYPVDQLINHV
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHH
YLPVRQRLVLDHNTSRIMSSMFDGALIEYAAASLFEMRRKPGKEAILMAWNVEERARLWL
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHH
EAWRLSLSGWHISVLADPIEAPRPELFPTQTLIVWTGMAPTRRQNELLQHWGEQGYKVIF
HHHHHHHCCEEEEEEECCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCEEEE
HAP
ECC
>Mature Secondary Structure 
AYYSIGDVAERCGINPVTLRAWQRRYGLLKPQRSEGGHRLFDEEDIQRIEEIKRWISNG
CCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
VPVGKVKALLETTSQDTEDDWSRLQEEMMSILRMANPAKLRARIISLGREYPVDQLINHV
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHH
YLPVRQRLVLDHNTSRIMSSMFDGALIEYAAASLFEMRRKPGKEAILMAWNVEERARLWL
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHH
EAWRLSLSGWHISVLADPIEAPRPELFPTQTLIVWTGMAPTRRQNELLQHWGEQGYKVIF
HHHHHHHCCEEEEEEECCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCEEEE
HAP
ECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]