Click here to switch to the map view.

The map label for this gene is ybcS

Identifier: 218703093

GI number: 218703093

Start: 5072788

End: 5073285

Strand: Direct

Name: ybcS

Synonym: ECIAI39_4875

Alternate gene names: 218703093

Gene position: 5072788-5073285 (Clockwise)

Preceding gene: 218703092

Following gene: 218703094

Centisome position: 98.84

GC content: 49.6

Gene sequence:

>498_bases
ATGCCTCCATCATTACGAAAAGCAGTTGCTGCTGCTATTGGTGGCGGAGCAATTGCTATAGCATCAGTGTTAATCACTGG
CCCAAGTGGTGACGATGGCCTGGAAGGTGTCAGCTACATACCATACAAAGATATCGTTGGCGTATGGACTGTATGTCACG
GACACACCGGAAAAGACATCATGCTCGGTAAAACGTATACCGAAGCAGAATGCAAAGCCCTCCTGAATAAAGACCTTGCC
ACGGTCGCCAGACAAATTAACCCGTACATCAAAGTCGATATACCGGAAACAACGCGCGGCGCTCTTTACTCGTTCGTCTA
CAACGTGGGTGCTGGCAATTTCAGAACATCGACGCTTCTTCGCAAAATAAACCAGGGCGATATCAAAGGCGCATGTGACC
AGCTACGTCGCTGGACATACGCTGGCGGTAAGCAATGGAAAGGCCTGATGACTCGTCGTGAGATTGAGCGTGAAGTCTGT
TTGTGGGGGCAACAATGA

Upstream 100 bases:

>100_bases
TAGGTGTGCTGGGTAGCCTGGTATTTGGCCTGCTGACGTACCTGACAAACCTTTATTTCAAGATTAAAGAAGATAAGCGC
AAGGCTGCGAGAGGTGAATA

Downstream 100 bases:

>100_bases
GCAGAGTAACCGCGATTATCTCCGCTCTGGTTATCTGCATCATCGTCTGCCTGTCGTGGGCGGTCAATCATTACCGTGAT
AACGCCATCGCCTACAAAGA

Product: putative lysozyme; DLP12 prophage

Products: NA

Alternate protein names: Endolysin; Lysis protein; Muramidase [H]

Number of amino acids: Translated: 165; Mature: 164

Protein sequence:

>165_residues
MPPSLRKAVAAAIGGGAIAIASVLITGPSGDDGLEGVSYIPYKDIVGVWTVCHGHTGKDIMLGKTYTEAECKALLNKDLA
TVARQINPYIKVDIPETTRGALYSFVYNVGAGNFRTSTLLRKINQGDIKGACDQLRRWTYAGGKQWKGLMTRREIEREVC
LWGQQ

Sequences:

>Translated_165_residues
MPPSLRKAVAAAIGGGAIAIASVLITGPSGDDGLEGVSYIPYKDIVGVWTVCHGHTGKDIMLGKTYTEAECKALLNKDLA
TVARQINPYIKVDIPETTRGALYSFVYNVGAGNFRTSTLLRKINQGDIKGACDQLRRWTYAGGKQWKGLMTRREIEREVC
LWGQQ
>Mature_164_residues
PPSLRKAVAAAIGGGAIAIASVLITGPSGDDGLEGVSYIPYKDIVGVWTVCHGHTGKDIMLGKTYTEAECKALLNKDLAT
VARQINPYIKVDIPETTRGALYSFVYNVGAGNFRTSTLLRKINQGDIKGACDQLRRWTYAGGKQWKGLMTRREIEREVCL
WGQQ

Specific function: Essential for lysis of bacterial cell wall, by showing cell wall hydrolyzing activity [H]

COG id: COG3772

COG function: function code R; Phage-related lysozyme (muraminidase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 24 family [H]

Homologues:

Organism=Escherichia coli, GI1786768, Length=165, Percent_Identity=98.7878787878788, Blast_Score=337, Evalue=3e-94,
Organism=Escherichia coli, GI1787836, Length=176, Percent_Identity=32.9545454545455, Blast_Score=74, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002196 [H]

Pfam domain/function: PF00959 Phage_lysozyme [H]

EC number: =3.2.1.17 [H]

Molecular weight: Translated: 17974; Mature: 17843

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPSLRKAVAAAIGGGAIAIASVLITGPSGDDGLEGVSYIPYKDIVGVWTVCHGHTGKDI
CCCHHHHHHHHHHCCCHHHHHHHHEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEE
MLGKTYTEAECKALLNKDLATVARQINPYIKVDIPETTRGALYSFVYNVGAGNFRTSTLL
EECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCCCHHHHHHH
RKINQGDIKGACDQLRRWTYAGGKQWKGLMTRREIEREVCLWGQQ
HHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PPSLRKAVAAAIGGGAIAIASVLITGPSGDDGLEGVSYIPYKDIVGVWTVCHGHTGKDI
CCHHHHHHHHHHCCCHHHHHHHHEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEE
MLGKTYTEAECKALLNKDLATVARQINPYIKVDIPETTRGALYSFVYNVGAGNFRTSTLL
EECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCCCHHHHHHH
RKINQGDIKGACDQLRRWTYAGGKQWKGLMTRREIEREVCLWGQQ
HHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]