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The map label for this gene is yjcC

Identifier: 218702726

GI number: 218702726

Start: 4684484

End: 4686070

Strand: Direct

Name: yjcC

Synonym: ECIAI39_4482

Alternate gene names: 218702726

Gene position: 4684484-4686070 (Clockwise)

Preceding gene: 218702724

Following gene: 218702728

Centisome position: 91.28

GC content: 44.61

Gene sequence:

>1587_bases
ATGAGTCATCGTGCACGACACCAATTACTGGCGTTGCCGGGCATTATCTTTTTAGTTCTCTTTCCCATCATTCTGTCGCT
ATGGATTGCCTTCTTTTGGGCAAAATCAGAAGTGAATAATCAGCTCCGAACCTTTGCTCAGCTGGCGTTGGATAAATCTG
AGCTGGTCATTCGTCAGGCAGATTTAGTGAGCGATGCAGCTGAACGCTATCAGGGGCAAGTTTGCACTCCAGCCCATCAA
AAGCGAATGTTGAATATTATTCGTGGCTATCTTTATATTAATGAATTGATCTATGCCCGTGATAACCATTTTTTATGCTC
ATCGCTGATAGCGCCTGTAAACGGCTATACGATTGCACCGGCCGATTATAAGCGTGAACCTAACGTTTCTATCTATTATT
ACCGCGATACGCCTTTTTTCTCTGACTATAAAATGACCTATATGCAGCGGGGAAATTATGTGGCGGTCATCAACCCTCTC
TTCTGGAGTGAAGTGATGTCTGATGATCCGACATTGCAATGGGGTGTGTATGATACGGTGACGAAAACCTTTTTCTCATT
AAGCAACGAGGCCTCGGCAGCAACGTTTTCTCCACTGATTCATTTGAATGATTTAACCGTACAAAGAAATGGCTATTTAT
ATGCGACAGTTTATTCGACAAAACGTCCAATTGCGGCCATTGTTGCGACTTCATATCAACGTCTTATAGCCCATTTTTAT
AATCATCTTATTTTTGCGTTACCCGCCGGTATTTTGGGGAGTCTTGTTCTGCTATTACTCTGGCTACGTATTCGACAAAA
CTATTTGTCTCCCAAACGCAAATTGCAACGCGCCCTCGAAAAACATCAACTTTGCCTTTATTACCAGCCAATAATCGATA
TCAAAACAGAAAAATGTATCGGAGCTGAAGCATTGTTACGTTGGCCTGGTGAGCAGGGGCAAGTAATGAATCCGGCAGAG
TTTATTCCGCTGGCAGAAAAGGAGGGGATGATCGGACAGGTAACTGATTATGTTATTGATAATGTCTTCCGCGATCTGGG
CGCATACCTGGCAACACATGCCGATCGCTATGTTTCTATTAACCTGTCGGCCTCCGATTTTCATACGTCACGGTTGATAG
CGCGAACCAATCAGAAAACAGAGCAATACGCGGTGCGTCCACAGCAAATTAAATTTGAAGTGACTGAACATGCATTTCTT
GATGTCGACAAAATGACACCAATTATTCTGGCTTTCCGCCAGGCTGGTTACGAAGTGGCAATTGATGATTTTGGTATTGG
CTACTCTAACTTGCATAACCTTAAATCATTGAATGTCGATATTTTGAAAATCGATAAATCGTTTGTTGAGACGCTGACCA
CCCATAAAACCAGTCATTTGATTGCGGAACACATCATCGAGCTGGCGCACAGTCTGGGGTTAAAAACGATCGCTGAAGGC
GTCGAAACTGAGGAACAGGTTAACTGGCTGCGCAAACGCGGCGTGCGCTATTGCCAGGGATGGTTCTTTGCGAAGGCGAT
GCCGCCGCAGGTGTTTATGCAATGGATGGAGCAATTACCCGCGCGGGAGTTAACGCGCGGGCAATAA

Upstream 100 bases:

>100_bases
CAAAAGTGCTATTTATACCGTAAGATTTATCTAAAGACGTCGGTGCCCAGGGTTTTCACCTTGCAATGGCCGGGTATAAA
CAGGCAGGAAATTGATAGCA

Downstream 100 bases:

>100_bases
AACTACAGGCGGTGGCGATAATCGCTGGGAGTGCGATCAAACTGCCGACGGAAAACGCGGGAGAAGGTCTGCTGCGAGAC
ATAACCCAGGTCCATTGCGA

Product: putative signal transduction protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 528; Mature: 527

Protein sequence:

>528_residues
MSHRARHQLLALPGIIFLVLFPIILSLWIAFFWAKSEVNNQLRTFAQLALDKSELVIRQADLVSDAAERYQGQVCTPAHQ
KRMLNIIRGYLYINELIYARDNHFLCSSLIAPVNGYTIAPADYKREPNVSIYYYRDTPFFSDYKMTYMQRGNYVAVINPL
FWSEVMSDDPTLQWGVYDTVTKTFFSLSNEASAATFSPLIHLNDLTVQRNGYLYATVYSTKRPIAAIVATSYQRLIAHFY
NHLIFALPAGILGSLVLLLLWLRIRQNYLSPKRKLQRALEKHQLCLYYQPIIDIKTEKCIGAEALLRWPGEQGQVMNPAE
FIPLAEKEGMIGQVTDYVIDNVFRDLGAYLATHADRYVSINLSASDFHTSRLIARTNQKTEQYAVRPQQIKFEVTEHAFL
DVDKMTPIILAFRQAGYEVAIDDFGIGYSNLHNLKSLNVDILKIDKSFVETLTTHKTSHLIAEHIIELAHSLGLKTIAEG
VETEEQVNWLRKRGVRYCQGWFFAKAMPPQVFMQWMEQLPARELTRGQ

Sequences:

>Translated_528_residues
MSHRARHQLLALPGIIFLVLFPIILSLWIAFFWAKSEVNNQLRTFAQLALDKSELVIRQADLVSDAAERYQGQVCTPAHQ
KRMLNIIRGYLYINELIYARDNHFLCSSLIAPVNGYTIAPADYKREPNVSIYYYRDTPFFSDYKMTYMQRGNYVAVINPL
FWSEVMSDDPTLQWGVYDTVTKTFFSLSNEASAATFSPLIHLNDLTVQRNGYLYATVYSTKRPIAAIVATSYQRLIAHFY
NHLIFALPAGILGSLVLLLLWLRIRQNYLSPKRKLQRALEKHQLCLYYQPIIDIKTEKCIGAEALLRWPGEQGQVMNPAE
FIPLAEKEGMIGQVTDYVIDNVFRDLGAYLATHADRYVSINLSASDFHTSRLIARTNQKTEQYAVRPQQIKFEVTEHAFL
DVDKMTPIILAFRQAGYEVAIDDFGIGYSNLHNLKSLNVDILKIDKSFVETLTTHKTSHLIAEHIIELAHSLGLKTIAEG
VETEEQVNWLRKRGVRYCQGWFFAKAMPPQVFMQWMEQLPARELTRGQ
>Mature_527_residues
SHRARHQLLALPGIIFLVLFPIILSLWIAFFWAKSEVNNQLRTFAQLALDKSELVIRQADLVSDAAERYQGQVCTPAHQK
RMLNIIRGYLYINELIYARDNHFLCSSLIAPVNGYTIAPADYKREPNVSIYYYRDTPFFSDYKMTYMQRGNYVAVINPLF
WSEVMSDDPTLQWGVYDTVTKTFFSLSNEASAATFSPLIHLNDLTVQRNGYLYATVYSTKRPIAAIVATSYQRLIAHFYN
HLIFALPAGILGSLVLLLLWLRIRQNYLSPKRKLQRALEKHQLCLYYQPIIDIKTEKCIGAEALLRWPGEQGQVMNPAEF
IPLAEKEGMIGQVTDYVIDNVFRDLGAYLATHADRYVSINLSASDFHTSRLIARTNQKTEQYAVRPQQIKFEVTEHAFLD
VDKMTPIILAFRQAGYEVAIDDFGIGYSNLHNLKSLNVDILKIDKSFVETLTTHKTSHLIAEHIIELAHSLGLKTIAEGV
ETEEQVNWLRKRGVRYCQGWFFAKAMPPQVFMQWMEQLPARELTRGQ

Specific function: Overexpression reduces biofilm formation [H]

COG id: COG4943

COG function: function code T; Predicted signal transduction protein containing sensor and EAL domains

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI1790496, Length=528, Percent_Identity=98.1060606060606, Blast_Score=1080, Evalue=0.0,
Organism=Escherichia coli, GI87081743, Length=528, Percent_Identity=33.3333333333333, Blast_Score=294, Evalue=8e-81,
Organism=Escherichia coli, GI87081980, Length=259, Percent_Identity=35.1351351351351, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1788502, Length=542, Percent_Identity=27.3062730627306, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI87081845, Length=279, Percent_Identity=31.8996415770609, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI226510982, Length=251, Percent_Identity=38.2470119521912, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI87081921, Length=244, Percent_Identity=36.0655737704918, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1787541, Length=249, Percent_Identity=32.5301204819277, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1788849, Length=236, Percent_Identity=30.9322033898305, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1786507, Length=242, Percent_Identity=31.404958677686, Blast_Score=122, Evalue=8e-29,
Organism=Escherichia coli, GI87082096, Length=235, Percent_Identity=30.6382978723404, Blast_Score=118, Evalue=8e-28,
Organism=Escherichia coli, GI1787055, Length=254, Percent_Identity=30.7086614173228, Blast_Score=116, Evalue=4e-27,
Organism=Escherichia coli, GI1787410, Length=225, Percent_Identity=28.4444444444444, Blast_Score=72, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: NA

Molecular weight: Translated: 60680; Mature: 60549

Theoretical pI: Translated: 8.39; Mature: 8.39

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHRARHQLLALPGIIFLVLFPIILSLWIAFFWAKSEVNNQLRTFAQLALDKSELVIRQA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
DLVSDAAERYQGQVCTPAHQKRMLNIIRGYLYINELIYARDNHFLCSSLIAPVNGYTIAP
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCEEECC
ADYKREPNVSIYYYRDTPFFSDYKMTYMQRGNYVAVINPLFWSEVMSDDPTLQWGVYDTV
CCCCCCCCCEEEEEECCCCCCCHHHHEEECCCEEEEECHHHHHHHHCCCCCEEECHHHHH
TKTFFSLSNEASAATFSPLIHLNDLTVQRNGYLYATVYSTKRPIAAIVATSYQRLIAHFY
HHHHHHHCCCCCCHHHCCEEEEECEEEEECCEEEEEEECCCCCHHHHHHHHHHHHHHHHH
NHLIFALPAGILGSLVLLLLWLRIRQNYLSPKRKLQRALEKHQLCLYYQPIIDIKTEKCI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCEEEEECCHHCCCCCHHC
GAEALLRWPGEQGQVMNPAEFIPLAEKEGMIGQVTDYVIDNVFRDLGAYLATHADRYVSI
CHHHHHHCCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
NLSASDFHTSRLIARTNQKTEQYAVRPQQIKFEVTEHAFLDVDKMTPIILAFRQAGYEVA
EECCCHHHHHHHHHHCCCCHHHHCCCCHHEEEEEHHHHHEEHHHCCHHHHHHHHCCCEEE
IDDFGIGYSNLHNLKSLNVDILKIDKSFVETLTTHKTSHLIAEHIIELAHSLGLKTIAEG
EECCCCCHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHC
VETEEQVNWLRKRGVRYCQGWFFAKAMPPQVFMQWMEQLPARELTRGQ
CCHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHCCCC
>Mature Secondary Structure 
SHRARHQLLALPGIIFLVLFPIILSLWIAFFWAKSEVNNQLRTFAQLALDKSELVIRQA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
DLVSDAAERYQGQVCTPAHQKRMLNIIRGYLYINELIYARDNHFLCSSLIAPVNGYTIAP
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCEEECC
ADYKREPNVSIYYYRDTPFFSDYKMTYMQRGNYVAVINPLFWSEVMSDDPTLQWGVYDTV
CCCCCCCCCEEEEEECCCCCCCHHHHEEECCCEEEEECHHHHHHHHCCCCCEEECHHHHH
TKTFFSLSNEASAATFSPLIHLNDLTVQRNGYLYATVYSTKRPIAAIVATSYQRLIAHFY
HHHHHHHCCCCCCHHHCCEEEEECEEEEECCEEEEEEECCCCCHHHHHHHHHHHHHHHHH
NHLIFALPAGILGSLVLLLLWLRIRQNYLSPKRKLQRALEKHQLCLYYQPIIDIKTEKCI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCEEEEECCHHCCCCCHHC
GAEALLRWPGEQGQVMNPAEFIPLAEKEGMIGQVTDYVIDNVFRDLGAYLATHADRYVSI
CHHHHHHCCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
NLSASDFHTSRLIARTNQKTEQYAVRPQQIKFEVTEHAFLDVDKMTPIILAFRQAGYEVA
EECCCHHHHHHHHHHCCCCHHHHCCCCHHEEEEEHHHHHEEHHHCCHHHHHHHHCCCEEE
IDDFGIGYSNLHNLKSLNVDILKIDKSFVETLTTHKTSHLIAEHIIELAHSLGLKTIAEG
EECCCCCHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHC
VETEEQVNWLRKRGVRYCQGWFFAKAMPPQVFMQWMEQLPARELTRGQ
CCHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]