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The map label for this gene is ygfQ

Identifier: 218701593

GI number: 218701593

Start: 3454227

End: 3455594

Strand: Direct

Name: ygfQ

Synonym: ECIAI39_3299

Alternate gene names: 218701593

Gene position: 3454227-3455594 (Clockwise)

Preceding gene: 218701592

Following gene: 218701596

Centisome position: 67.31

GC content: 52.41

Gene sequence:

>1368_bases
ATGTCTGGAGACATCCTACAAACACCGGACGCACCAAAGCCACAAGGCGCGCTGGATAATTATTTTAAAATTACCGCTCG
TGGCAGTACCGTTCGTCAGGAAGTACTGGCTGGCTTAACGACCTTTCTGGCCATGGTTTATTCCGTTATCGTTGTTCCGG
GAATGCTGGGCAAAGCAGGTTTTCCTCCCGCAGCTGTGTTTGTTGCCACCTGTCTGGTCGCGGGCTTCGGCTCGTTGCTG
ATGGGGTTATGGGCCAATTTGCCAATGGCGATTGGTTGCGCGATTTCCCTGACGGCGTTTACCGCATTCAGTCTGGTACT
CGGGCAACAAATTAGCGTTCCTGTCGCACTGGGCGCGGTCTTTCTGATGGGCGTCATCTTCACCGCCATTTCCGTAACCG
GTGTGCGTACCTGGATCTTACGTAATTTACCGATGGGGATAGCTCACGGTACAGGTATCGGTATCGGCCTGTTTCTGCTG
CTGATTGCTGCTAACGGTGTGGGAATGGTTATCAAAAACCCGATTGAAGGCTTGCCAGTGGCACTCGGTGCGTTTACCTC
CTTCCCGGTGATGATGAGCTTACTGGGGCTGGCGGTCATCTTCGGTCTGGAAAAGTGCCGCGTACCTGGCGGGATCTTGT
TGGTGATTATTGCAATTTCGATCATCGGCTTAATCTTTGATCCAGCGGTGAAGTACCACGGTCTGGTGGCGATGCCCAGT
CTGACTGGCGAAGATGGTAAGTCGCTGATTTTCAGCCTCGATATTATGGGGGCACTCCAGCCAACTGTACTTCCGAGTGT
ACTGGCATTGGTGATGACCGCAGTGTTCGACGCCACCGGTACCATCCGTGCCGTCGCCGGTCAGGCGAATTTGTTAGATA
AAGACAACCAGATCATCAACGGCGGTAAAGCCCTGACCAGTGACTCAGTAAGTTCAATATTCTCCGGCCTGGTGGGCGCA
GCGCCCGCAGCGGTTTATATCGAATCAGCGGCAGGAACCGCCGCCGGGGGTAAAACAGGGTTAACCGCAACCGTAGTGGG
GGCGTTATTCCTGTTGATTCTGTTTTTATCACCACTGTCATTTTTGATCCCTGGTTACGCCACTGCACCCGCTCTGATGT
ACGTAGGTTTGCTGATGTTAAGTAACGTCTCGAAGCTGGATTTCAACGATTTTATTGACGCAATGGCTGGCCTGGTGTGT
GCCGTGTTTATCGTTCTGACTTGTAATATCGTTACCGGTATTATGCTGGGCTTTGTGACACTGGTCGTAGGCCGCGTCTT
TGCACGCGAATGGCAAAAGCTGAATATTGGTACGGTAATCATTACTGCCGCACTGGTCGCATTTTACGCGGGTGGATGGG
CTATCTAA

Upstream 100 bases:

>100_bases
TGGGCGATGACCGTTCGATCTACCGCACCTACGTTGATGGTCGTCTGGTGTACGAACGCAACTAATAATAAAACTTTAAC
ATCCTCGTGAGGACATCATT

Downstream 100 bases:

>100_bases
TAGATTCTCCGCGCCTTTCAGCGCGGAGATTTCTTTCACAGAGGATTCTCACCGCTGGCAACAATACGCTGCTGGCGGAC
TCGCCTGAGTTCTCTTTCAG

Product: putative transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 454

Protein sequence:

>455_residues
MSGDILQTPDAPKPQGALDNYFKITARGSTVRQEVLAGLTTFLAMVYSVIVVPGMLGKAGFPPAAVFVATCLVAGFGSLL
MGLWANLPMAIGCAISLTAFTAFSLVLGQQISVPVALGAVFLMGVIFTAISVTGVRTWILRNLPMGIAHGTGIGIGLFLL
LIAANGVGMVIKNPIEGLPVALGAFTSFPVMMSLLGLAVIFGLEKCRVPGGILLVIIAISIIGLIFDPAVKYHGLVAMPS
LTGEDGKSLIFSLDIMGALQPTVLPSVLALVMTAVFDATGTIRAVAGQANLLDKDNQIINGGKALTSDSVSSIFSGLVGA
APAAVYIESAAGTAAGGKTGLTATVVGALFLLILFLSPLSFLIPGYATAPALMYVGLLMLSNVSKLDFNDFIDAMAGLVC
AVFIVLTCNIVTGIMLGFVTLVVGRVFAREWQKLNIGTVIITAALVAFYAGGWAI

Sequences:

>Translated_455_residues
MSGDILQTPDAPKPQGALDNYFKITARGSTVRQEVLAGLTTFLAMVYSVIVVPGMLGKAGFPPAAVFVATCLVAGFGSLL
MGLWANLPMAIGCAISLTAFTAFSLVLGQQISVPVALGAVFLMGVIFTAISVTGVRTWILRNLPMGIAHGTGIGIGLFLL
LIAANGVGMVIKNPIEGLPVALGAFTSFPVMMSLLGLAVIFGLEKCRVPGGILLVIIAISIIGLIFDPAVKYHGLVAMPS
LTGEDGKSLIFSLDIMGALQPTVLPSVLALVMTAVFDATGTIRAVAGQANLLDKDNQIINGGKALTSDSVSSIFSGLVGA
APAAVYIESAAGTAAGGKTGLTATVVGALFLLILFLSPLSFLIPGYATAPALMYVGLLMLSNVSKLDFNDFIDAMAGLVC
AVFIVLTCNIVTGIMLGFVTLVVGRVFAREWQKLNIGTVIITAALVAFYAGGWAI
>Mature_454_residues
SGDILQTPDAPKPQGALDNYFKITARGSTVRQEVLAGLTTFLAMVYSVIVVPGMLGKAGFPPAAVFVATCLVAGFGSLLM
GLWANLPMAIGCAISLTAFTAFSLVLGQQISVPVALGAVFLMGVIFTAISVTGVRTWILRNLPMGIAHGTGIGIGLFLLL
IAANGVGMVIKNPIEGLPVALGAFTSFPVMMSLLGLAVIFGLEKCRVPGGILLVIIAISIIGLIFDPAVKYHGLVAMPSL
TGEDGKSLIFSLDIMGALQPTVLPSVLALVMTAVFDATGTIRAVAGQANLLDKDNQIINGGKALTSDSVSSIFSGLVGAA
PAAVYIESAAGTAAGGKTGLTATVVGALFLLILFLSPLSFLIPGYATAPALMYVGLLMLSNVSKLDFNDFIDAMAGLVCA
VFIVLTCNIVTGIMLGFVTLVVGRVFAREWQKLNIGTVIITAALVAFYAGGWAI

Specific function: Unknown

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily

Homologues:

Organism=Escherichia coli, GI48994909, Length=455, Percent_Identity=100, Blast_Score=880, Evalue=0.0,
Organism=Escherichia coli, GI1790499, Length=450, Percent_Identity=82.4444444444444, Blast_Score=726, Evalue=0.0,
Organism=Escherichia coli, GI87082309, Length=447, Percent_Identity=37.1364653243848, Blast_Score=274, Evalue=8e-75,
Organism=Escherichia coli, GI1790150, Length=435, Percent_Identity=35.8620689655172, Blast_Score=249, Evalue=2e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YGFQ_ECOLI (Q46817)

Other databases:

- EMBL:   U28375
- EMBL:   U28375
- EMBL:   U00096
- EMBL:   AP009048
- PIR:   D65072
- PIR:   E65072
- RefSeq:   AP_003444.1
- RefSeq:   YP_026186.1
- ProteinModelPortal:   Q46817
- STRING:   Q46817
- EnsemblBacteria:   EBESCT00000002174
- EnsemblBacteria:   EBESCT00000015719
- GeneID:   2847748
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW5467
- KEGG:   eco:b4464
- EchoBASE:   EB2879
- EcoGene:   EG13067
- eggNOG:   COG2252
- GeneTree:   EBGT00050000009705
- HOGENOM:   HBG750189
- OMA:   VKYQGFF
- ProtClustDB:   CLSK870037
- BioCyc:   EcoCyc:G7504-MONOMER
- Genevestigator:   Q46817
- InterPro:   IPR006043
- PANTHER:   PTHR11119

Pfam domain/function: PF00860 Xan_ur_permease

EC number: NA

Molecular weight: Translated: 46759; Mature: 46627

Theoretical pI: Translated: 7.84; Mature: 7.84

Prosite motif: PS01116 XANTH_URACIL_PERMASE

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x2503b22c)-; HASH(0x24f8d7e4)-; HASH(0x248b01ac)-; HASH(0x24ad92cc)-; HASH(0x2417d480)-; HASH(0x24f4bba4)-; HASH(0x2384b300)-; HASH(0x24100114)-; HASH(0x24f9257c)-; HASH(0x235dbbac)-; HASH(0x2491a534)-; HASH(0x24248654)-;

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCH
>Mature Secondary Structure 
SGDILQTPDAPKPQGALDNYFKITARGSTVRQEVLAGLTTFLAMVYSVIVVPGMLGKAG
CCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
FPPAAVFVATCLVAGFGSLLMGLWANLPMAIGCAISLTAFTAFSLVLGQQISVPVALGAV
CCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
FLMGVIFTAISVTGVRTWILRNLPMGIAHGTGIGIGLFLLLIAANGVGMVIKNPIEGLPV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCH
ALGAFTSFPVMMSLLGLAVIFGLEKCRVPGGILLVIIAISIIGLIFDPAVKYHGLVAMPS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECC
LTGEDGKSLIFSLDIMGALQPTVLPSVLALVMTAVFDATGTIRAVAGQANLLDKDNQIIN
CCCCCCCCEEEEEHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCEEC
GGKALTSDSVSSIFSGLVGAAPAAVYIESAAGTAAGGKTGLTATVVGALFLLILFLSPLS
CCCCCCHHHHHHHHHHHHHCCCHHHEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
FLIPGYATAPALMYVGLLMLSNVSKLDFNDFIDAMAGLVCAVFIVLTCNIVTGIMLGFVT
HHCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVVGRVFAREWQKLNIGTVIITAALVAFYAGGWAI
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503