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The map label for this gene is yihP

Identifier: 218701423

GI number: 218701423

Start: 3251746

End: 3253164

Strand: Direct

Name: yihP

Synonym: ECIAI39_3123

Alternate gene names: 218701423

Gene position: 3251746-3253164 (Clockwise)

Preceding gene: 218701422

Following gene: 218701424

Centisome position: 63.36

GC content: 52.08

Gene sequence:

>1419_bases
GTGGGGAAACTCACGGGCAAAGGGAGAACAACGATGAGTCACATCACAACGGAAGATCCAGCAACTTTACGCCTGCCCTT
TAAAGAGAAACTCTCTTACGGTATTGGCGACCTGGCCTCTAACATCCTGCTGGATATTGGTACGCTTTATCTTTTGAAGT
TTTATACCGACGTTCTGGGGCTGCCTGGCACCTATGGCGGCATTATCTTTTTGATTTCAAAATTCTTTACTGCGTTTACC
GATATGGGAACAGGCATCATGCTGGATTCCCGACGCAAGATCGGCCCAAAAGGCAAGTTCCGTCCTTTTATTCTGTATGC
GTCATTCCCGGTCACCCTGCTGGCGATCGCCAACTTTATCGGTACGCCGTTCGATGTCACCGGTAAAACGGTGATGGCCA
CCATCCTGTTTATGCTTTACGGACTGTTTTTCAGCATGATGAACTGCTCGTATGGCGCGATGGTCCCCGCTATTACTAAA
AACCCCAACGAACGTGCATCGCTGGCAGCATGGCGTCAGGGTGGCGCTACATTAGGCCTGCTGCTGTGTACGGTGGGATT
CGTGCCGGTTATGAATCTTATCGAAGGTAATCAGCAACTTGGCTATATCTTCGCCGCCACGCTGTTTTCACTGTTCGGCC
TGCTGTTTATGTGGATCTGCTACTCGGGCGTGAAAGAGCGTTATGTCGAAACCCAACCTACCAATCCGGCGCAAAAGCCT
GGCTTGTTGCAGTCTTTCCGCGCGATTGCTGGTAACCGCCCACTGTTCATTCTGTGTATTGCCAACCTCTGCACTTTAGG
GGCGTTTAACGTCAAGCTCGCCATTCAGGTCTATTACACCCAGTACGTGCTCAACGATCCCATCCTGTTGTCATATATGG
GATTTTTCAGCATGGGCTGTATTTTCATCGGCGTGTTCCTGATGCCCGGCGCAGTCAGACGTTTTGGTAAGAAGAAGGTC
TATATCGGCGGCCTGCTGATTTGGGTGCTTGGCGATCTGCTCAACTATTTCTTTGGCGGCGGTTCGGTCAGCTTCGTGGC
GTTCTCCTGCCTGGCATTCTTCGGCTCAGCGTTTGTTAACAGCCTGAACTGGGCGCTGGTTTCCGACACCGTCGAGTACG
GCGAGTGGCGCACCGGTGTGCGTTCGGAAGGTACGGTCTACACCGGTTTCACCTTCTTTCGCAAAGTATCTCAGGCGCTG
GCAGGTTTCTTCCCAGGCTGGATGCTGACGCAAATCGGCTATGTGCCAAACGTCGCCCAGGCTGACCACACTATCGAAGG
GTTGCGCCAACTGATCTTCATCTACCCAAGCGCACTGGCAGTAGTCACCATCGTGGCAATGGGTTGCTTCTACAGTCTGA
ACGAGAAGATGTACGTCCGCATTGTTGAAGAGATAGAAGCCCGTAAACGCACGGCGTAA

Upstream 100 bases:

>100_bases
CGTTAATGCGCCCATCGGTAAACCGCCGGTCTTTTATCGCGCCGATAGCGAATGGGCGGCACTGTTCGCGTCGTTAAAAA
GCATCTAATCACATCCGCCC

Downstream 100 bases:

>100_bases
TTATAATAAACAACGCCCTGCGGGGCGTTATAAGGAGTGATTATGTCTGACCATAATCCACTGACATTAAGACTGAATCT
GCGGGAAAAAATCGCCTATG

Product: putative transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 472; Mature: 471

Protein sequence:

>472_residues
MGKLTGKGRTTMSHITTEDPATLRLPFKEKLSYGIGDLASNILLDIGTLYLLKFYTDVLGLPGTYGGIIFLISKFFTAFT
DMGTGIMLDSRRKIGPKGKFRPFILYASFPVTLLAIANFIGTPFDVTGKTVMATILFMLYGLFFSMMNCSYGAMVPAITK
NPNERASLAAWRQGGATLGLLLCTVGFVPVMNLIEGNQQLGYIFAATLFSLFGLLFMWICYSGVKERYVETQPTNPAQKP
GLLQSFRAIAGNRPLFILCIANLCTLGAFNVKLAIQVYYTQYVLNDPILLSYMGFFSMGCIFIGVFLMPGAVRRFGKKKV
YIGGLLIWVLGDLLNYFFGGGSVSFVAFSCLAFFGSAFVNSLNWALVSDTVEYGEWRTGVRSEGTVYTGFTFFRKVSQAL
AGFFPGWMLTQIGYVPNVAQADHTIEGLRQLIFIYPSALAVVTIVAMGCFYSLNEKMYVRIVEEIEARKRTA

Sequences:

>Translated_472_residues
MGKLTGKGRTTMSHITTEDPATLRLPFKEKLSYGIGDLASNILLDIGTLYLLKFYTDVLGLPGTYGGIIFLISKFFTAFT
DMGTGIMLDSRRKIGPKGKFRPFILYASFPVTLLAIANFIGTPFDVTGKTVMATILFMLYGLFFSMMNCSYGAMVPAITK
NPNERASLAAWRQGGATLGLLLCTVGFVPVMNLIEGNQQLGYIFAATLFSLFGLLFMWICYSGVKERYVETQPTNPAQKP
GLLQSFRAIAGNRPLFILCIANLCTLGAFNVKLAIQVYYTQYVLNDPILLSYMGFFSMGCIFIGVFLMPGAVRRFGKKKV
YIGGLLIWVLGDLLNYFFGGGSVSFVAFSCLAFFGSAFVNSLNWALVSDTVEYGEWRTGVRSEGTVYTGFTFFRKVSQAL
AGFFPGWMLTQIGYVPNVAQADHTIEGLRQLIFIYPSALAVVTIVAMGCFYSLNEKMYVRIVEEIEARKRTA
>Mature_471_residues
GKLTGKGRTTMSHITTEDPATLRLPFKEKLSYGIGDLASNILLDIGTLYLLKFYTDVLGLPGTYGGIIFLISKFFTAFTD
MGTGIMLDSRRKIGPKGKFRPFILYASFPVTLLAIANFIGTPFDVTGKTVMATILFMLYGLFFSMMNCSYGAMVPAITKN
PNERASLAAWRQGGATLGLLLCTVGFVPVMNLIEGNQQLGYIFAATLFSLFGLLFMWICYSGVKERYVETQPTNPAQKPG
LLQSFRAIAGNRPLFILCIANLCTLGAFNVKLAIQVYYTQYVLNDPILLSYMGFFSMGCIFIGVFLMPGAVRRFGKKKVY
IGGLLIWVLGDLLNYFFGGGSVSFVAFSCLAFFGSAFVNSLNWALVSDTVEYGEWRTGVRSEGTVYTGFTFFRKVSQALA
GFFPGWMLTQIGYVPNVAQADHTIEGLRQLIFIYPSALAVVTIVAMGCFYSLNEKMYVRIVEEIEARKRTA

Specific function: Unknown

COG id: COG2211

COG function: function code G; Na+/melibiose symporter and related transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:galactoside symporter (TC 2.A.2) family [H]

Homologues:

Organism=Homo sapiens, GI122937339, Length=448, Percent_Identity=24.3303571428571, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI145693206, Length=461, Percent_Identity=99.1323210412148, Blast_Score=930, Evalue=0.0,
Organism=Escherichia coli, GI48994989, Length=456, Percent_Identity=65.1315789473684, Blast_Score=624, Evalue=1e-180,
Organism=Escherichia coli, GI1787902, Length=453, Percent_Identity=33.112582781457, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI87082306, Length=451, Percent_Identity=29.2682926829268, Blast_Score=179, Evalue=3e-46,
Organism=Escherichia coli, GI1786466, Length=420, Percent_Identity=27.6190476190476, Blast_Score=173, Evalue=3e-44,
Organism=Escherichia coli, GI1790561, Length=450, Percent_Identity=26.2222222222222, Blast_Score=140, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001927
- InterPro:   IPR018043 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 52128; Mature: 51997

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: PS00872 NA_GALACTOSIDE_SYMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKLTGKGRTTMSHITTEDPATLRLPFKEKLSYGIGDLASNILLDIGTLYLLKFYTDVLG
CCCCCCCCCCHHHHCCCCCCCEEECCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHC
LPGTYGGIIFLISKFFTAFTDMGTGIMLDSRRKIGPKGKFRPFILYASFPVTLLAIANFI
CCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCEEEEEECHHHHHHHHHHHH
GTPFDVTGKTVMATILFMLYGLFFSMMNCSYGAMVPAITKNPNERASLAAWRQGGATLGL
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHH
LLCTVGFVPVMNLIEGNQQLGYIFAATLFSLFGLLFMWICYSGVKERYVETQPTNPAQKP
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
GLLQSFRAIAGNRPLFILCIANLCTLGAFNVKLAIQVYYTQYVLNDPILLSYMGFFSMGC
CHHHHHHHHHCCCCEEEHHHHHHHHCCCCCEEEEEEEEEEHHHHCCCHHHHHHHHHHHHH
IFIGVFLMPGAVRRFGKKKVYIGGLLIWVLGDLLNYFFGGGSVSFVAFSCLAFFGSAFVN
HHHHHHHCCHHHHHHCCCEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
SLNWALVSDTVEYGEWRTGVRSEGTVYTGFTFFRKVSQALAGFFPGWMLTQIGYVPNVAQ
HCCHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHCCHHHHHHHCCCCCHHH
ADHTIEGLRQLIFIYPSALAVVTIVAMGCFYSLNEKMYVRIVEEIEARKRTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GKLTGKGRTTMSHITTEDPATLRLPFKEKLSYGIGDLASNILLDIGTLYLLKFYTDVLG
CCCCCCCCCHHHHCCCCCCCEEECCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHC
LPGTYGGIIFLISKFFTAFTDMGTGIMLDSRRKIGPKGKFRPFILYASFPVTLLAIANFI
CCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCEEEEEECHHHHHHHHHHHH
GTPFDVTGKTVMATILFMLYGLFFSMMNCSYGAMVPAITKNPNERASLAAWRQGGATLGL
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHH
LLCTVGFVPVMNLIEGNQQLGYIFAATLFSLFGLLFMWICYSGVKERYVETQPTNPAQKP
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
GLLQSFRAIAGNRPLFILCIANLCTLGAFNVKLAIQVYYTQYVLNDPILLSYMGFFSMGC
CHHHHHHHHHCCCCEEEHHHHHHHHCCCCCEEEEEEEEEEHHHHCCCHHHHHHHHHHHHH
IFIGVFLMPGAVRRFGKKKVYIGGLLIWVLGDLLNYFFGGGSVSFVAFSCLAFFGSAFVN
HHHHHHHCCHHHHHHCCCEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
SLNWALVSDTVEYGEWRTGVRSEGTVYTGFTFFRKVSQALAGFFPGWMLTQIGYVPNVAQ
HCCHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHCCHHHHHHHCCCCCHHH
ADHTIEGLRQLIFIYPSALAVVTIVAMGCFYSLNEKMYVRIVEEIEARKRTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346018; 9278503 [H]