Click here to switch to the map view.

The map label for this gene is yihQ

Identifier: 218701422

GI number: 218701422

Start: 3249697

End: 3251733

Strand: Direct

Name: yihQ

Synonym: ECIAI39_3122

Alternate gene names: 218701422

Gene position: 3249697-3251733 (Clockwise)

Preceding gene: 218701421

Following gene: 218701423

Centisome position: 63.32

GC content: 54.25

Gene sequence:

>2037_bases
ATGGATACGCCACGCCCACAGCTATTAGATTTTCAATTTCATCAGAATAACGACAGTTTTACTCTACGTTTTCAAGACCG
CCTTATTTTAATCCATAGCAAAGATAATCCTTGCTTATCGATTGGCTCAGGTATAGCGGATATCGATATGTTCCGCGGTA
ATTTCAGCATTAAAGATAAATTGCAGGAGAAAATTGCGCTTACCGACGCCATCGTCAGCCAGTCACCGGATGGCTGGTTA
ATCCATTTCAGCCGTGGTTCTGACATTAGCGCCACGCTGCGTATCTCTACCGACGATCAGGGCCGTTTATTGCTGGAACT
ACAAAACGACAACCTTAACCACAACCGTATCTGGCTGCGCCTTGCCGCTCAACCAGAGGACCATATCTACGGCTGCGGCG
AACAATTCTCCTACTTTGATCTGCGCGGCAAACCGTTCCCGCTATGGACCAGTGAACAAGGCGTTGGTCGCAACAAGCAA
ACCTATGTCACCTGGCAGGCCGACTGCAAAGAGAACGCGGGCGGCGACTATTACTGGACTTTCTTCCCGCAGCCTACGTT
TGTCAGCACGCAGAAGTATTACTGCCATGTTGATAACAGTTGCTACATGAACTTCGACTTTAGCGCCCCGGAATACCATG
AACTGGCGCTGTGGGAAGACAAAGCAACGCTGCGTTTTGAATGTGCTGATACATACATCTCCCTGCTGGAAAAATTAACT
GCCCTGCTGGGACGCCAGCCAGAACTGCCCGACTGGATTTATGACGGGGTAACGCTCGGCATTCAGGGCGGCACTGAGGT
GTGCCAGAAGAAACTGGACACCATGCGTAACGCGGGCGTGAAGGTCAACGGCATCTGGGCGCAGGACTGGTCCGGGATCC
GTATGACCTCGTTTGGTAAACGTGTGATGTGGAACTGGAAGTGGAACAGCGAAAACTATCCGCAACTGGATTCGCGTATT
AAACAGTGGAACAAAGAAGGCGTGCAGTTCCTCGCCTACATCAACCCGTATGTTGCCAGCGATAAGGACCTCTGCGCCGA
GGCGGCTTCACACGGCTATCTGGCAAAAGATGCCTCTGGCGGCGACTATCTGGTGGAGTTTGGCGAGTTCTATGGCGGCG
TTGTCGATCTCACCAATCCAGAAGCCTACGCCTGGTTCAAGGAAGTGATCAAAAAGAACATGATTGAACTCGGCTGCGGC
GGCTGGATGGCTGACTTCGGCGAGTATCTGCCCACCGACACTTACCTGCATAACGGCGTCAGCGCGGAAATTATGCATAA
CGCCTGGCCCGCACTGTGGGCGAAATGTAACTACGAAGCCCTTGAAGAAACGGGCAAGCTTGGCGAGATCCTTTTCTTTA
TGCGCGCCGGTTCTACCGGTAGCCAGAAATACTCCACCATGATGTGGGCGGGCGACCAGAACGTCGACTGGAGTCTCGAC
GATGGCCTGGCGTCGGTTGTCCCGGCGGCGCTGTCGCTGGCAATGACCGGACATGGCCTGCATCACAGCGATATTGGCGG
TTACACCACCCTGTTTGAGATGAAGCGCAGCAAAGAGCTGCTGCTGCGCTGGTGCGATTTCAGCGCCTTCACGCCGATGA
TGCGCACCCACGAAGGTAACCGTCCTGGCGACAACTGGCAGTTTGACGGCGACGCGGAAACCATCGCCCATTTTGCCCGT
ATGACCACCGTCTTCACCACCCTGAAACCTTACCTGAAAGAGGCCGTCGCGCTGAATGCGAAGTCCGGCCTGCCGGTTAT
GCGCCCGCTGTTCCTGCATTACGAAGACGACGCGCAGACCTACACCCTGAAATATCAGTACCTGTTAGGCCGCGACATTC
TGGTCGCTCCGGTGCATGAAGAAGGCCGTAGCGACTGGACGCTCTATCTGCCGGAGGATAACTGGGTCCATGCCTGGACG
GGTGAAGCGTTCCGGGGCGGGGAAGTTACCGTTAATGCGCCCATCGGTAAACCGCCGGTCTTTTATCGCGCCGATAGCGA
ATGGGCGGCACTGTTCGCGTCGTTAAAAAGCATCTAA

Upstream 100 bases:

>100_bases
CTGTAAAGTTTATATATATCAGTTTTATGAGAATCATTTTACATAAGCCTGTAATAACGGGAAGGAAACAATCTCGTCCT
CAACTCTATGGAGATTATTT

Downstream 100 bases:

>100_bases
TCACATCCGCCCGTGGGGAAACTCACGGGCAAAGGGAGAACAACGATGAGTCACATCACAACGGAAGATCCAGCAACTTT
ACGCCTGCCCTTTAAAGAGA

Product: alpha-glucosidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 678; Mature: 678

Protein sequence:

>678_residues
MDTPRPQLLDFQFHQNNDSFTLRFQDRLILIHSKDNPCLSIGSGIADIDMFRGNFSIKDKLQEKIALTDAIVSQSPDGWL
IHFSRGSDISATLRISTDDQGRLLLELQNDNLNHNRIWLRLAAQPEDHIYGCGEQFSYFDLRGKPFPLWTSEQGVGRNKQ
TYVTWQADCKENAGGDYYWTFFPQPTFVSTQKYYCHVDNSCYMNFDFSAPEYHELALWEDKATLRFECADTYISLLEKLT
ALLGRQPELPDWIYDGVTLGIQGGTEVCQKKLDTMRNAGVKVNGIWAQDWSGIRMTSFGKRVMWNWKWNSENYPQLDSRI
KQWNKEGVQFLAYINPYVASDKDLCAEAASHGYLAKDASGGDYLVEFGEFYGGVVDLTNPEAYAWFKEVIKKNMIELGCG
GWMADFGEYLPTDTYLHNGVSAEIMHNAWPALWAKCNYEALEETGKLGEILFFMRAGSTGSQKYSTMMWAGDQNVDWSLD
DGLASVVPAALSLAMTGHGLHHSDIGGYTTLFEMKRSKELLLRWCDFSAFTPMMRTHEGNRPGDNWQFDGDAETIAHFAR
MTTVFTTLKPYLKEAVALNAKSGLPVMRPLFLHYEDDAQTYTLKYQYLLGRDILVAPVHEEGRSDWTLYLPEDNWVHAWT
GEAFRGGEVTVNAPIGKPPVFYRADSEWAALFASLKSI

Sequences:

>Translated_678_residues
MDTPRPQLLDFQFHQNNDSFTLRFQDRLILIHSKDNPCLSIGSGIADIDMFRGNFSIKDKLQEKIALTDAIVSQSPDGWL
IHFSRGSDISATLRISTDDQGRLLLELQNDNLNHNRIWLRLAAQPEDHIYGCGEQFSYFDLRGKPFPLWTSEQGVGRNKQ
TYVTWQADCKENAGGDYYWTFFPQPTFVSTQKYYCHVDNSCYMNFDFSAPEYHELALWEDKATLRFECADTYISLLEKLT
ALLGRQPELPDWIYDGVTLGIQGGTEVCQKKLDTMRNAGVKVNGIWAQDWSGIRMTSFGKRVMWNWKWNSENYPQLDSRI
KQWNKEGVQFLAYINPYVASDKDLCAEAASHGYLAKDASGGDYLVEFGEFYGGVVDLTNPEAYAWFKEVIKKNMIELGCG
GWMADFGEYLPTDTYLHNGVSAEIMHNAWPALWAKCNYEALEETGKLGEILFFMRAGSTGSQKYSTMMWAGDQNVDWSLD
DGLASVVPAALSLAMTGHGLHHSDIGGYTTLFEMKRSKELLLRWCDFSAFTPMMRTHEGNRPGDNWQFDGDAETIAHFAR
MTTVFTTLKPYLKEAVALNAKSGLPVMRPLFLHYEDDAQTYTLKYQYLLGRDILVAPVHEEGRSDWTLYLPEDNWVHAWT
GEAFRGGEVTVNAPIGKPPVFYRADSEWAALFASLKSI
>Mature_678_residues
MDTPRPQLLDFQFHQNNDSFTLRFQDRLILIHSKDNPCLSIGSGIADIDMFRGNFSIKDKLQEKIALTDAIVSQSPDGWL
IHFSRGSDISATLRISTDDQGRLLLELQNDNLNHNRIWLRLAAQPEDHIYGCGEQFSYFDLRGKPFPLWTSEQGVGRNKQ
TYVTWQADCKENAGGDYYWTFFPQPTFVSTQKYYCHVDNSCYMNFDFSAPEYHELALWEDKATLRFECADTYISLLEKLT
ALLGRQPELPDWIYDGVTLGIQGGTEVCQKKLDTMRNAGVKVNGIWAQDWSGIRMTSFGKRVMWNWKWNSENYPQLDSRI
KQWNKEGVQFLAYINPYVASDKDLCAEAASHGYLAKDASGGDYLVEFGEFYGGVVDLTNPEAYAWFKEVIKKNMIELGCG
GWMADFGEYLPTDTYLHNGVSAEIMHNAWPALWAKCNYEALEETGKLGEILFFMRAGSTGSQKYSTMMWAGDQNVDWSLD
DGLASVVPAALSLAMTGHGLHHSDIGGYTTLFEMKRSKELLLRWCDFSAFTPMMRTHEGNRPGDNWQFDGDAETIAHFAR
MTTVFTTLKPYLKEAVALNAKSGLPVMRPLFLHYEDDAQTYTLKYQYLLGRDILVAPVHEEGRSDWTLYLPEDNWVHAWT
GEAFRGGEVTVNAPIGKPPVFYRADSEWAALFASLKSI

Specific function: Exhibits hydrolysis activity against alpha-glucosyl fluoride, although natural substrates, such as alpha-glucobioses are scarcely hydrolyzed [H]

COG id: COG1501

COG function: function code G; Alpha-glucosidases, family 31 of glycosyl hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 31 family [H]

Homologues:

Organism=Homo sapiens, GI153791946, Length=349, Percent_Identity=24.6418338108883, Blast_Score=109, Evalue=1e-23,
Organism=Homo sapiens, GI38202257, Length=351, Percent_Identity=25.6410256410256, Blast_Score=100, Evalue=8e-21,
Organism=Homo sapiens, GI88900491, Length=349, Percent_Identity=25.5014326647564, Blast_Score=100, Evalue=9e-21,
Organism=Homo sapiens, GI66346737, Length=397, Percent_Identity=25.6926952141058, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI119393895, Length=407, Percent_Identity=22.8501228501229, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI119393893, Length=407, Percent_Identity=22.8501228501229, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI119393891, Length=407, Percent_Identity=22.8501228501229, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI221316699, Length=242, Percent_Identity=27.6859504132231, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI310115361, Length=236, Percent_Identity=28.8135593220339, Blast_Score=78, Evalue=2e-14,
Organism=Escherichia coli, GI2367323, Length=678, Percent_Identity=98.5250737463127, Blast_Score=1397, Evalue=0.0,
Organism=Escherichia coli, GI2367256, Length=550, Percent_Identity=24.5454545454545, Blast_Score=174, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI17560798, Length=380, Percent_Identity=22.6315789473684, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17560800, Length=380, Percent_Identity=22.6315789473684, Blast_Score=103, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI71991189, Length=366, Percent_Identity=24.5901639344262, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI32563849, Length=231, Percent_Identity=30.7359307359307, Blast_Score=83, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI71985706, Length=237, Percent_Identity=29.1139240506329, Blast_Score=81, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6319706, Length=381, Percent_Identity=22.3097112860892, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24650054, Length=345, Percent_Identity=25.7971014492754, Blast_Score=102, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24643749, Length=357, Percent_Identity=23.8095238095238, Blast_Score=80, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24643753, Length=357, Percent_Identity=23.8095238095238, Blast_Score=80, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24643751, Length=357, Percent_Identity=23.8095238095238, Blast_Score=80, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24643746, Length=357, Percent_Identity=23.8095238095238, Blast_Score=80, Evalue=5e-15,
Organism=Drosophila melanogaster, GI21357605, Length=357, Percent_Identity=23.8095238095238, Blast_Score=80, Evalue=5e-15,
Organism=Drosophila melanogaster, GI28571440, Length=379, Percent_Identity=20.3166226912929, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI28571438, Length=380, Percent_Identity=21.3157894736842, Blast_Score=72, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011013
- InterPro:   IPR000322
- InterPro:   IPR017853 [H]

Pfam domain/function: PF01055 Glyco_hydro_31 [H]

EC number: =3.2.1.20 [H]

Molecular weight: Translated: 77159; Mature: 77159

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTPRPQLLDFQFHQNNDSFTLRFQDRLILIHSKDNPCLSIGSGIADIDMFRGNFSIKDK
CCCCCCCEEEEEEECCCCEEEEEEECEEEEEECCCCCEEEECCCCEEEEEECCCCCHHHH
LQEKIALTDAIVSQSPDGWLIHFSRGSDISATLRISTDDQGRLLLELQNDNLNHNRIWLR
HHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEEECCCCCEEEEEEECCCCCCCEEEEE
LAAQPEDHIYGCGEQFSYFDLRGKPFPLWTSEQGVGRNKQTYVTWQADCKENAGGDYYWT
EECCCCCCEEECCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEE
FFPQPTFVSTQKYYCHVDNSCYMNFDFSAPEYHELALWEDKATLRFECADTYISLLEKLT
ECCCCCEEECCEEEEEECCEEEEEEECCCCCCEEEEEEECCCEEEEEEHHHHHHHHHHHH
ALLGRQPELPDWIYDGVTLGIQGGTEVCQKKLDTMRNAGVKVNGIWAQDWSGIRMTSFGK
HHHCCCCCCCCHHHCCEEEEECCCHHHHHHHHHHHHHCCEEEEEEEECCCCCEEEECCCC
RVMWNWKWNSENYPQLDSRIKQWNKEGVQFLAYINPYVASDKDLCAEAASHGYLAKDASG
EEEEEEEECCCCCCHHHHHHHHHCHHHEEEEEEECCCCCCCHHHHHHHHHCCCEEECCCC
GDYLVEFGEFYGGVVDLTNPEAYAWFKEVIKKNMIELGCGGWMADFGEYLPTDTYLHNGV
CHHEEEEHHHCCCEEECCCCHHHHHHHHHHHHHHEEECCCCHHHHHHHHCCCCHHHHCCC
SAEIMHNAWPALWAKCNYEALEETGKLGEILFFMRAGSTGSQKYSTMMWAGDQNVDWSLD
CHHHHHCCCHHHHHCCCHHHHHHCCCCEEEEEEEECCCCCCCCEEEEEEECCCCCCCCCC
DGLASVVPAALSLAMTGHGLHHSDIGGYTTLFEMKRSKELLLRWCDFSAFTPMMRTHEGN
CCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHCCCHHHHCCCC
RPGDNWQFDGDAETIAHFARMTTVFTTLKPYLKEAVALNAKSGLPVMRPLFLHYEDDAQT
CCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCEEEEEEECCCEE
YTLKYQYLLGRDILVAPVHEEGRSDWTLYLPEDNWVHAWTGEAFRGGEVTVNAPIGKPPV
EEEEEEEEECCCEEEEECCCCCCCCEEEECCCCCEEEEECCCCCCCCEEEEECCCCCCCE
FYRADSEWAALFASLKSI
EEECCCHHHHHHHHHHCC
>Mature Secondary Structure
MDTPRPQLLDFQFHQNNDSFTLRFQDRLILIHSKDNPCLSIGSGIADIDMFRGNFSIKDK
CCCCCCCEEEEEEECCCCEEEEEEECEEEEEECCCCCEEEECCCCEEEEEECCCCCHHHH
LQEKIALTDAIVSQSPDGWLIHFSRGSDISATLRISTDDQGRLLLELQNDNLNHNRIWLR
HHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEEECCCCCEEEEEEECCCCCCCEEEEE
LAAQPEDHIYGCGEQFSYFDLRGKPFPLWTSEQGVGRNKQTYVTWQADCKENAGGDYYWT
EECCCCCCEEECCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEE
FFPQPTFVSTQKYYCHVDNSCYMNFDFSAPEYHELALWEDKATLRFECADTYISLLEKLT
ECCCCCEEECCEEEEEECCEEEEEEECCCCCCEEEEEEECCCEEEEEEHHHHHHHHHHHH
ALLGRQPELPDWIYDGVTLGIQGGTEVCQKKLDTMRNAGVKVNGIWAQDWSGIRMTSFGK
HHHCCCCCCCCHHHCCEEEEECCCHHHHHHHHHHHHHCCEEEEEEEECCCCCEEEECCCC
RVMWNWKWNSENYPQLDSRIKQWNKEGVQFLAYINPYVASDKDLCAEAASHGYLAKDASG
EEEEEEEECCCCCCHHHHHHHHHCHHHEEEEEEECCCCCCCHHHHHHHHHCCCEEECCCC
GDYLVEFGEFYGGVVDLTNPEAYAWFKEVIKKNMIELGCGGWMADFGEYLPTDTYLHNGV
CHHEEEEHHHCCCEEECCCCHHHHHHHHHHHHHHEEECCCCHHHHHHHHCCCCHHHHCCC
SAEIMHNAWPALWAKCNYEALEETGKLGEILFFMRAGSTGSQKYSTMMWAGDQNVDWSLD
CHHHHHCCCHHHHHCCCHHHHHHCCCCEEEEEEEECCCCCCCCEEEEEEECCCCCCCCCC
DGLASVVPAALSLAMTGHGLHHSDIGGYTTLFEMKRSKELLLRWCDFSAFTPMMRTHEGN
CCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHCCCHHHHCCCC
RPGDNWQFDGDAETIAHFARMTTVFTTLKPYLKEAVALNAKSGLPVMRPLFLHYEDDAQT
CCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCEEEEEEECCCEE
YTLKYQYLLGRDILVAPVHEEGRSDWTLYLPEDNWVHAWTGEAFRGGEVTVNAPIGKPPV
EEEEEEEEECCCEEEEECCCCCCCCEEEECCCCCEEEEECCCCCCCCEEEEECCCCCCCE
FYRADSEWAALFASLKSI
EEECCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8346018; 9278503 [H]