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The map label for this gene is scrK [H]

Identifier: 218701263

GI number: 218701263

Start: 3066836

End: 3067756

Strand: Direct

Name: scrK [H]

Synonym: ECIAI39_2963

Alternate gene names: 218701263

Gene position: 3066836-3067756 (Clockwise)

Preceding gene: 218701262

Following gene: 218701264

Centisome position: 59.76

GC content: 47.99

Gene sequence:

>921_bases
ATGAGCGCAAGAGTATGGGTACTCGGTGATGCGGTTGTTGATTTATTACCCGAAAGCCAGGGGAGACTACTACAGTGTCC
TGGCGGGGCGCCTGCTAATGTTGCAGTCGGTATCGCAAGGCTGGGGGGGAAAAGTGCCTTTATTGGCAAAGTTGGCGATG
ATCCTTTCGGTCGCTTTATGTATCAGACACTGAGTACAGAAAATGTTGATACACGTTATATGTCTCTTGATCCTCAACAA
CGCACCTCAATTGTGGCTGTAGGACTTGATGAGCAAGGAGAAAGAAACTTTACCTTTATGGTACGCCCAAGTGCCGATCT
TTTTTTACAACCTGGTGACCTTCCTGCATTTGGGCCGGGTGAATGGCTCCATCTTTGTTCCATTGCGCTCAGTGCAGAAC
CTTCCCGAAGTACCGCATTTCTGGCTATGGAGAAAATACGTCAGGCTGGCGGAAACATCAGTTTTGATCCCAATATCCGC
AGCGATCTCTGGCAGAGTGAAGCGCTATTAAGGAAATACCTTGATCGCGCACTTTCGCTGGCGAATATCGCTAAATTGTC
CGAAGAAGAGTTGCTATTCATCAGTGGCGAAAGCCAGGTTCAGCAAGGCGCATATTCATTAGTACAACGTTATTCGTTGA
CTTTATTGCTTATTACACAAGGAAAAAATGGCGTACTTGTGTATTTTCAGGGGCAGTTTATCCACTATCCCGCCAAACCT
GTTTCTGTCGTCGATACGACCGGGGCAGGAGATGCTTTTGTCGCTGGATTACTTGCAGGTCTGGCTGATTCTGGAATACC
AACAAATACCAGACAGCTTGAACGAATCATTGCACAAGCTCAGATTTGTGGTGCTCTGGCGACCACGGCTAAAGGCGCGA
TGACCGCCTTACCCCGACAACACGATCTCCCTTCACAATAG

Upstream 100 bases:

>100_bases
CGGGTAACCACTGCTGAATATTGTTCTCTCCTGAGCAGTGTTTATGCTTTAATTGCTAAACCGATTTAATTAGTTTAGCA
ATTAGTATATTGGAGCCTTT

Downstream 100 bases:

>100_bases
TGATCCTGCTGTTGTATCTGTAACCCGATTTGTCGTGCCTGTCACATTTACTAAATCGGTTTAGCGAAAATAATTGCTCT
GTCTAAAAAGTCAGCTTTAT

Product: aminoimidazole riboside kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MSARVWVLGDAVVDLLPESQGRLLQCPGGAPANVAVGIARLGGKSAFIGKVGDDPFGRFMYQTLSTENVDTRYMSLDPQQ
RTSIVAVGLDEQGERNFTFMVRPSADLFLQPGDLPAFGPGEWLHLCSIALSAEPSRSTAFLAMEKIRQAGGNISFDPNIR
SDLWQSEALLRKYLDRALSLANIAKLSEEELLFISGESQVQQGAYSLVQRYSLTLLLITQGKNGVLVYFQGQFIHYPAKP
VSVVDTTGAGDAFVAGLLAGLADSGIPTNTRQLERIIAQAQICGALATTAKGAMTALPRQHDLPSQ

Sequences:

>Translated_306_residues
MSARVWVLGDAVVDLLPESQGRLLQCPGGAPANVAVGIARLGGKSAFIGKVGDDPFGRFMYQTLSTENVDTRYMSLDPQQ
RTSIVAVGLDEQGERNFTFMVRPSADLFLQPGDLPAFGPGEWLHLCSIALSAEPSRSTAFLAMEKIRQAGGNISFDPNIR
SDLWQSEALLRKYLDRALSLANIAKLSEEELLFISGESQVQQGAYSLVQRYSLTLLLITQGKNGVLVYFQGQFIHYPAKP
VSVVDTTGAGDAFVAGLLAGLADSGIPTNTRQLERIIAQAQICGALATTAKGAMTALPRQHDLPSQ
>Mature_305_residues
SARVWVLGDAVVDLLPESQGRLLQCPGGAPANVAVGIARLGGKSAFIGKVGDDPFGRFMYQTLSTENVDTRYMSLDPQQR
TSIVAVGLDEQGERNFTFMVRPSADLFLQPGDLPAFGPGEWLHLCSIALSAEPSRSTAFLAMEKIRQAGGNISFDPNIRS
DLWQSEALLRKYLDRALSLANIAKLSEEELLFISGESQVQQGAYSLVQRYSLTLLLITQGKNGVLVYFQGQFIHYPAKPV
SVVDTTGAGDAFVAGLLAGLADSGIPTNTRQLERIIAQAQICGALATTAKGAMTALPRQHDLPSQ

Specific function: Unknown

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI87082343, Length=293, Percent_Identity=31.0580204778157, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI87082281, Length=274, Percent_Identity=25.9124087591241, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1789775, Length=289, Percent_Identity=28.719723183391, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI87081971, Length=318, Percent_Identity=25.7861635220126, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1790193, Length=239, Percent_Identity=27.1966527196653, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17532905, Length=249, Percent_Identity=29.718875502008, Blast_Score=68, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.4 [H]

Molecular weight: Translated: 32899; Mature: 32768

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS00583 PFKB_KINASES_1 ; PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSARVWVLGDAVVDLLPESQGRLLQCPGGAPANVAVGIARLGGKSAFIGKVGDDPFGRFM
CCCEEEEECHHHHHHCCCCCCCEEECCCCCCCHHEEEHHHCCCCCEEEECCCCCHHHHHH
YQTLSTENVDTRYMSLDPQQRTSIVAVGLDEQGERNFTFMVRPSADLFLQPGDLPAFGPG
HHHHCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCEEEEECCCCCEEEECCCCCCCCCC
EWLHLCSIALSAEPSRSTAFLAMEKIRQAGGNISFDPNIRSDLWQSEALLRKYLDRALSL
HHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHH
ANIAKLSEEELLFISGESQVQQGAYSLVQRYSLTLLLITQGKNGVLVYFQGQFIHYPAKP
HHHHHCCCCCEEEEECCHHHHHHHHHHHHHHCEEEEEEEECCCCEEEEEECEEEECCCCC
VSVVDTTGAGDAFVAGLLAGLADSGIPTNTRQLERIIAQAQICGALATTAKGAMTALPRQ
CEEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCC
HDLPSQ
CCCCCC
>Mature Secondary Structure 
SARVWVLGDAVVDLLPESQGRLLQCPGGAPANVAVGIARLGGKSAFIGKVGDDPFGRFM
CCEEEEECHHHHHHCCCCCCCEEECCCCCCCHHEEEHHHCCCCCEEEECCCCCHHHHHH
YQTLSTENVDTRYMSLDPQQRTSIVAVGLDEQGERNFTFMVRPSADLFLQPGDLPAFGPG
HHHHCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCEEEEECCCCCEEEECCCCCCCCCC
EWLHLCSIALSAEPSRSTAFLAMEKIRQAGGNISFDPNIRSDLWQSEALLRKYLDRALSL
HHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHH
ANIAKLSEEELLFISGESQVQQGAYSLVQRYSLTLLLITQGKNGVLVYFQGQFIHYPAKP
HHHHHCCCCCEEEEECCHHHHHHHHHHHHHHCEEEEEEEECCCCEEEEEECEEEECCCCC
VSVVDTTGAGDAFVAGLLAGLADSGIPTNTRQLERIIAQAQICGALATTAKGAMTALPRQ
CEEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCC
HDLPSQ
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1809835 [H]