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The map label for this gene is 218700779

Identifier: 218700779

GI number: 218700779

Start: 2539947

End: 2541386

Strand: Reverse

Name: 218700779

Synonym: ECIAI39_2452

Alternate gene names: NA

Gene position: 2541386-2539947 (Counterclockwise)

Preceding gene: 218700780

Following gene: 218700775

Centisome position: 49.52

GC content: 43.89

Gene sequence:

>1440_bases
ATGACAATAAATCAGCCATCCTTTAGCTCGGCGATGATCATTCTGGCTATTATTTTTATATTGTTCCTGGCTGGCGTCGG
GATACTTAATGCCCCCGTGGAGTTTGTGTTGATTGTAGTGACGTTGGTTACTGCTTTTTATGCCAGGTATTATGGTGCGC
GCTGGAGAGATATTGTTAATATATTTATGAGTAAAATTAAAGAAGCAGTTCCGGCAATGCTTATTTTACTCTCTATCGGG
ATGTTGATTGGCTGCTGGATAGTTTCCGGAACAATTCCTTTAATGGTTTTATATGGTCTGGAAATGGTAAGCCCTCATTA
TCTCTATTTGACAGCCTTCCTGGTGACAGTTTGTATCTCTCTTTTTACCGGAACATCATGGGGTACGGCGGGTACTATCG
GCGTAGCATTGATGGCCGTGGCTGCGGCGATGGACGTTTCATTACCGATTACCGCCGGGGCGGTGATTTCGGGTTCCTAT
TTTGGTGATAAATTATCGCCTCTTTCCGATACCACCAATATGGCAGCGATGGCTGCGGGCGTCGAGTTATGGCAAAGTAT
TCGCAATATGATGTATACCTCTATTCCTGCTTTTTTCGTCTCATGTTTTGGCTTCTGGTGGGCCGGAAGCGGCCTGAATG
AAATGAATCAGCAAATTGAGAATATTGCCATTATGAGAGATGTATTACAGCGACTTTTTTGGTTAAATCCGCTGTGTTTG
CTTCCCGCACTACTGGTGTTCTTCGGTGCGCTAAAAAAATGGGATACTACAGTAGTATTAATTGCCTCTTCGTTCCTCGC
TTTATTTATTGGTGCAATATTTCAGCCGATTGCATGGATGGATATGGTTCAATCCGCTGTAAATGGTTTTAAAGATACCA
TGTTACTACAATTTGATGGTATTGCCAGCGATCCGCTGGTGGCTAAAAATCTTATGGTGCTTCTCAATCGCGGCGGAATC
TATTCTATGGTCAGTCCGATTGTGGTGATGCTTTGTGCATTTTTATTTGCATCAGCACTTGAGGCATCTGGCGGATTAAA
TATTGTCCTGCAACGTCTGGTTAAGAAATTACGCTCTGTAACCAGCGTCGTTCTGGCTACGATGTTTTCCAGTACATTAT
TAGTGGCCTGTACTGGAAATGCCGTCATTAGCTTTTTTCTGGTCAAAAGCATGTATGATCCGTGCTATGACGAACATCAA
TTGCATAAAGTGAATATGTCGCGGGCCATGGAGTCTGGAGCCACTTTGCTGGAAGGACTTTTTCCCTGGACTATTTCCGG
GATGTTTATGGCGAAAACGCTTGGTGTTGCAACACTTGATTACCTGCCGTGGACGTTTTTTAATTTGAGTTGCTTTGCGA
TCGCTCTTTTATTTGCTTTTCTGGCAAAATGGAGCCGTTTTGGCACTCGCTATGCCGCGCCCGAAGTAGCTCGTAGATAA

Upstream 100 bases:

>100_bases
AGATCCCGCGCGGATTAATTCGTCTCTCGCTTGGGCAGGAAAATGCCGCTCTTTTAATTGCCGATCTGGAGCGTGCTTTT
GACTCGCTAAGGACGAAACC

Downstream 100 bases:

>100_bases
AGGTAAATAACTCGCTTTCATGCCTGGCAATAATTGCCAGGCATGAAAGAACGTAAAAAATTACTGGACTACGTTTTCCA
GCGCCTCTTCTAAATCGTAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 479; Mature: 478

Protein sequence:

>479_residues
MTINQPSFSSAMIILAIIFILFLAGVGILNAPVEFVLIVVTLVTAFYARYYGARWRDIVNIFMSKIKEAVPAMLILLSIG
MLIGCWIVSGTIPLMVLYGLEMVSPHYLYLTAFLVTVCISLFTGTSWGTAGTIGVALMAVAAAMDVSLPITAGAVISGSY
FGDKLSPLSDTTNMAAMAAGVELWQSIRNMMYTSIPAFFVSCFGFWWAGSGLNEMNQQIENIAIMRDVLQRLFWLNPLCL
LPALLVFFGALKKWDTTVVLIASSFLALFIGAIFQPIAWMDMVQSAVNGFKDTMLLQFDGIASDPLVAKNLMVLLNRGGI
YSMVSPIVVMLCAFLFASALEASGGLNIVLQRLVKKLRSVTSVVLATMFSSTLLVACTGNAVISFFLVKSMYDPCYDEHQ
LHKVNMSRAMESGATLLEGLFPWTISGMFMAKTLGVATLDYLPWTFFNLSCFAIALLFAFLAKWSRFGTRYAAPEVARR

Sequences:

>Translated_479_residues
MTINQPSFSSAMIILAIIFILFLAGVGILNAPVEFVLIVVTLVTAFYARYYGARWRDIVNIFMSKIKEAVPAMLILLSIG
MLIGCWIVSGTIPLMVLYGLEMVSPHYLYLTAFLVTVCISLFTGTSWGTAGTIGVALMAVAAAMDVSLPITAGAVISGSY
FGDKLSPLSDTTNMAAMAAGVELWQSIRNMMYTSIPAFFVSCFGFWWAGSGLNEMNQQIENIAIMRDVLQRLFWLNPLCL
LPALLVFFGALKKWDTTVVLIASSFLALFIGAIFQPIAWMDMVQSAVNGFKDTMLLQFDGIASDPLVAKNLMVLLNRGGI
YSMVSPIVVMLCAFLFASALEASGGLNIVLQRLVKKLRSVTSVVLATMFSSTLLVACTGNAVISFFLVKSMYDPCYDEHQ
LHKVNMSRAMESGATLLEGLFPWTISGMFMAKTLGVATLDYLPWTFFNLSCFAIALLFAFLAKWSRFGTRYAAPEVARR
>Mature_478_residues
TINQPSFSSAMIILAIIFILFLAGVGILNAPVEFVLIVVTLVTAFYARYYGARWRDIVNIFMSKIKEAVPAMLILLSIGM
LIGCWIVSGTIPLMVLYGLEMVSPHYLYLTAFLVTVCISLFTGTSWGTAGTIGVALMAVAAAMDVSLPITAGAVISGSYF
GDKLSPLSDTTNMAAMAAGVELWQSIRNMMYTSIPAFFVSCFGFWWAGSGLNEMNQQIENIAIMRDVLQRLFWLNPLCLL
PALLVFFGALKKWDTTVVLIASSFLALFIGAIFQPIAWMDMVQSAVNGFKDTMLLQFDGIASDPLVAKNLMVLLNRGGIY
SMVSPIVVMLCAFLFASALEASGGLNIVLQRLVKKLRSVTSVVLATMFSSTLLVACTGNAVISFFLVKSMYDPCYDEHQL
HKVNMSRAMESGATLLEGLFPWTISGMFMAKTLGVATLDYLPWTFFNLSCFAIALLFAFLAKWSRFGTRYAAPEVARR

Specific function: Unknown

COG id: COG1757

COG function: function code C; Na+/H+ antiporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nhaC Na(+)/H(+) antiporter family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004770
- InterPro:   IPR018461 [H]

Pfam domain/function: PF03553 Na_H_antiporter [H]

EC number: NA

Molecular weight: Translated: 52425; Mature: 52294

Theoretical pI: Translated: 8.18; Mature: 8.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTINQPSFSSAMIILAIIFILFLAGVGILNAPVEFVLIVVTLVTAFYARYYGARWRDIVN
CCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
IFMSKIKEAVPAMLILLSIGMLIGCWIVSGTIPLMVLYGLEMVSPHYLYLTAFLVTVCIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
LFTGTSWGTAGTIGVALMAVAAAMDVSLPITAGAVISGSYFGDKLSPLSDTTNMAAMAAG
HHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHEECCCCCCCCCCCCCHHHHHHHHHH
VELWQSIRNMMYTSIPAFFVSCFGFWWAGSGLNEMNQQIENIAIMRDVLQRLFWLNPLCL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
LPALLVFFGALKKWDTTVVLIASSFLALFIGAIFQPIAWMDMVQSAVNGFKDTMLLQFDG
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECC
IASDPLVAKNLMVLLNRGGIYSMVSPIVVMLCAFLFASALEASGGLNIVLQRLVKKLRSV
CCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
TSVVLATMFSSTLLVACTGNAVISFFLVKSMYDPCYDEHQLHKVNMSRAMESGATLLEGL
HHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
FPWTISGMFMAKTLGVATLDYLPWTFFNLSCFAIALLFAFLAKWSRFGTRYAAPEVARR
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCC
>Mature Secondary Structure 
TINQPSFSSAMIILAIIFILFLAGVGILNAPVEFVLIVVTLVTAFYARYYGARWRDIVN
CCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH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HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]