Click here to switch to the map view.

The map label for this gene is chbC [H]

Identifier: 218700183

GI number: 218700183

Start: 1913902

End: 1915224

Strand: Reverse

Name: chbC [H]

Synonym: ECIAI39_1832

Alternate gene names: 218700183

Gene position: 1915224-1913902 (Counterclockwise)

Preceding gene: 218700184

Following gene: 218700182

Centisome position: 37.32

GC content: 43.16

Gene sequence:

>1323_bases
ATGAGATTAATGGCCTCATTCGAACGTGGAATGGAACGTTTTCTTGTTCCAGTTGCTATCAAGTTAAACTCACAAAAACA
TGTTGCAGCGGTGAGAGATGGATTCGTTTTTACGTTTCCAATTATCATGGCAAGTTCATTAATTATACTAATTAACTTTG
CCATATTATCGCCCGACGGTTTTATTGCCGGATTACTGCATCTGAATAGCATTTTCCCCAACCTTGAAAAAGCACAAGCT
ATTTTTACTCCGGTAATGAATGGTTCTGTAAATATCATGTCAATTATGATTGCTTTCCTGGTCGCCAGGAATGTGGCGAT
TAGCTATGAGCAAGATGATCTTTTATGCGGATTAACGGCAATAGGAGCATTTTTTATTGTTTATACCCCATATCAGATGA
TAGATGGGCAGGCATTCCTGACGACCAAATATCTCGGCGCGCAGGGGTTGTTTGTTGCTGTTATCGTTGCATTGATCACC
AGTGAAATATTTTGTCGCTTAGCTCGAAACCCCAAAATCACCATCACGATGCCGGCAGCTGTACCTCCTGCGGTAGCGCG
TTCATTTAAAGTTTTATTGCCCATATTTTTTGTCATGGTGTTCTTTTCCGCACTTAATTATTGCCTGACATTGATATCCC
CGGCAGGATTAAACGATCTCATTTACACATTAATTCAGACGCCGCTCAAACATATGGGAACGAATATCTTTGCGGTAATT
ATCCTGGGGGCTGTGGGTAATTTCCTCTGGGTGCTGGGGATCCACGGACCTAATACAACGTCGGCAATTCGAGAAACCGT
TTTTTCTGAGGCTAATCTGGAGAATCTCTCCTGGGCCGCTCAACACGGTACTACCTGGGGCGCGCCATATCCGATTACCT
GGACTTCTATTAATGATGCATTTGCCAACTGCGGCGGTTCAGGTATGACGTTGGGGTTATTGTTGGCTATTTTTATCGCT
TCTAAGCGTGCGGAATACCGTGATCTGGCAAAAATGTCATTTATCCCCGGTATTTTCAATATCAATGAACCGATAATGTT
CGGCCTTCCTATTGTACTTAACCCCATCATGATGGTGCCGTTTATTATGGTTCCTATTGTTAACTGTGCCATTGGTTACT
TCTTTGTTTCGATGGAAATTATTCCACCGGTTGCTTATGCCGTGCCCTGGACTACGCCCGGACCTTTAATTGCTTTCCTC
GGAACCGGGGGAAACTGGCTGGCGTTACTGGTGGGTTTTTTATGTTTAGGTGTGGCGACAATGATCTATTTACCTTTTGT
TATTGCCGCCAACAAGGTCAATAACTTAACAACTAACGGATAA

Upstream 100 bases:

>100_bases
TTAAACTATTACCTGAACTAACTTTTCACACATCATAAAATGGATATGGCATACATGCTTTATTGGGATGTATAAATATC
CAGAACAACAGGTATAAAAA

Downstream 100 bases:

>100_bases
TGCCATTTACACAGGAAGGAGATGTTGATGTTTGCAGATGAAGAACTTGTTATGGAGTTACTGGTCAACGCAGGACAGGC
CCGTTCTGATGCGATGGAAG

Product: putative phosphotransferase system IIC component

Products: pyruvate; diacetylchitobiose-6-phosphate [Cytoplasm]; cellobiose-6-phosphate [Cytoplasm] [C]

Alternate protein names: EIIC-Chb; PTS system N,N'-diacetylchitobiose-specific EIIC component [H]

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MRLMASFERGMERFLVPVAIKLNSQKHVAAVRDGFVFTFPIIMASSLIILINFAILSPDGFIAGLLHLNSIFPNLEKAQA
IFTPVMNGSVNIMSIMIAFLVARNVAISYEQDDLLCGLTAIGAFFIVYTPYQMIDGQAFLTTKYLGAQGLFVAVIVALIT
SEIFCRLARNPKITITMPAAVPPAVARSFKVLLPIFFVMVFFSALNYCLTLISPAGLNDLIYTLIQTPLKHMGTNIFAVI
ILGAVGNFLWVLGIHGPNTTSAIRETVFSEANLENLSWAAQHGTTWGAPYPITWTSINDAFANCGGSGMTLGLLLAIFIA
SKRAEYRDLAKMSFIPGIFNINEPIMFGLPIVLNPIMMVPFIMVPIVNCAIGYFFVSMEIIPPVAYAVPWTTPGPLIAFL
GTGGNWLALLVGFLCLGVATMIYLPFVIAANKVNNLTTNG

Sequences:

>Translated_440_residues
MRLMASFERGMERFLVPVAIKLNSQKHVAAVRDGFVFTFPIIMASSLIILINFAILSPDGFIAGLLHLNSIFPNLEKAQA
IFTPVMNGSVNIMSIMIAFLVARNVAISYEQDDLLCGLTAIGAFFIVYTPYQMIDGQAFLTTKYLGAQGLFVAVIVALIT
SEIFCRLARNPKITITMPAAVPPAVARSFKVLLPIFFVMVFFSALNYCLTLISPAGLNDLIYTLIQTPLKHMGTNIFAVI
ILGAVGNFLWVLGIHGPNTTSAIRETVFSEANLENLSWAAQHGTTWGAPYPITWTSINDAFANCGGSGMTLGLLLAIFIA
SKRAEYRDLAKMSFIPGIFNINEPIMFGLPIVLNPIMMVPFIMVPIVNCAIGYFFVSMEIIPPVAYAVPWTTPGPLIAFL
GTGGNWLALLVGFLCLGVATMIYLPFVIAANKVNNLTTNG
>Mature_440_residues
MRLMASFERGMERFLVPVAIKLNSQKHVAAVRDGFVFTFPIIMASSLIILINFAILSPDGFIAGLLHLNSIFPNLEKAQA
IFTPVMNGSVNIMSIMIAFLVARNVAISYEQDDLLCGLTAIGAFFIVYTPYQMIDGQAFLTTKYLGAQGLFVAVIVALIT
SEIFCRLARNPKITITMPAAVPPAVARSFKVLLPIFFVMVFFSALNYCLTLISPAGLNDLIYTLIQTPLKHMGTNIFAVI
ILGAVGNFLWVLGIHGPNTTSAIRETVFSEANLENLSWAAQHGTTWGAPYPITWTSINDAFANCGGSGMTLGLLLAIFIA
SKRAEYRDLAKMSFIPGIFNINEPIMFGLPIVLNPIMMVPFIMVPIVNCAIGYFFVSMEIIPPVAYAVPWTTPGPLIAFL
GTGGNWLALLVGFLCLGVATMIYLPFVIAANKVNNLTTNG

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788032, Length=443, Percent_Identity=36.7945823927765, Blast_Score=254, Evalue=1e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003352
- InterPro:   IPR004796
- InterPro:   IPR004501 [H]

Pfam domain/function: PF02378 PTS_EIIC [H]

EC number: NA

Molecular weight: Translated: 47799; Mature: 47799

Theoretical pI: Translated: 8.11; Mature: 8.11

Prosite motif: PS51105 PTS_EIIC_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLMASFERGMERFLVPVAIKLNSQKHVAAVRDGFVFTFPIIMASSLIILINFAILSPDG
CCCHHHHHHHHHHHEEEEEEEECCCHHHHHHHCCCHHEEHHHHHHHHHHHHHHHHCCCCH
FIAGLLHLNSIFPNLEKAQAIFTPVMNGSVNIMSIMIAFLVARNVAISYEQDDLLCGLTA
HHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEECCCCHHHHHHH
IGAFFIVYTPYQMIDGQAFLTTKYLGAQGLFVAVIVALITSEIFCRLARNPKITITMPAA
HHHHHHHCCCHHHHCCCEEEEEHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCC
VPPAVARSFKVLLPIFFVMVFFSALNYCLTLISPAGLNDLIYTLIQTPLKHMGTNIFAVI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHH
ILGAVGNFLWVLGIHGPNTTSAIRETVFSEANLENLSWAAQHGTTWGAPYPITWTSINDA
HHHHHHCEEEEEEECCCCHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCEEECCCCHH
FANCGGSGMTLGLLLAIFIASKRAEYRDLAKMSFIPGIFNINEPIMFGLPIVLNPIMMVP
HHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHCCCHHHHHHHHHHH
FIMVPIVNCAIGYFFVSMEIIPPVAYAVPWTTPGPLIAFLGTGGNWLALLVGFLCLGVAT
HHHHHHHHHHHHHHHHHHHHHCCHHEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHH
MIYLPFVIAANKVNNLTTNG
HHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MRLMASFERGMERFLVPVAIKLNSQKHVAAVRDGFVFTFPIIMASSLIILINFAILSPDG
CCCHHHHHHHHHHHEEEEEEEECCCHHHHHHHCCCHHEEHHHHHHHHHHHHHHHHCCCCH
FIAGLLHLNSIFPNLEKAQAIFTPVMNGSVNIMSIMIAFLVARNVAISYEQDDLLCGLTA
HHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEECCCCHHHHHHH
IGAFFIVYTPYQMIDGQAFLTTKYLGAQGLFVAVIVALITSEIFCRLARNPKITITMPAA
HHHHHHHCCCHHHHCCCEEEEEHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCC
VPPAVARSFKVLLPIFFVMVFFSALNYCLTLISPAGLNDLIYTLIQTPLKHMGTNIFAVI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHH
ILGAVGNFLWVLGIHGPNTTSAIRETVFSEANLENLSWAAQHGTTWGAPYPITWTSINDA
HHHHHHCEEEEEEECCCCHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCEEECCCCHH
FANCGGSGMTLGLLLAIFIASKRAEYRDLAKMSFIPGIFNINEPIMFGLPIVLNPIMMVP
HHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHCCCHHHHHHHHHHH
FIMVPIVNCAIGYFFVSMEIIPPVAYAVPWTTPGPLIAFLGTGGNWLALLVGFLCLGVAT
HHHHHHHHHHHHHHHHHHHHHCCHHEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHH
MIYLPFVIAANKVNNLTTNG
HHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: diacetylchitobiose [Periplasm]; phosphoenolpyruvate; cellobiose [Periplasm] [C]

Specific reaction: phosphoenolpyruvate + diacetylchitobiose [Periplasm] = pyruvate + diacetylchitobiose-6-phosphate [Cytoplasm] phosphoenolpyruvate + cellobiose [Periplasm] = cellobiose-6-phosphate [Cytoplasm] + pyruvate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2179047; 9097039; 9278503; 2092358; 9405618; 10913117 [H]