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The map label for this gene is sufB

Identifier: 218699752

GI number: 218699752

Start: 1443237

End: 1444724

Strand: Direct

Name: sufB

Synonym: ECIAI39_1375

Alternate gene names: 218699752

Gene position: 1443237-1444724 (Clockwise)

Preceding gene: 218699751

Following gene: 218699753

Centisome position: 28.12

GC content: 51.48

Gene sequence:

>1488_bases
ATGTCTCGTAATACTGAAGCAACTGACGATGTCAAAACCTGGACCGGCGGCCCGCTGAATTATAAAGAAGGATTCTTCAC
CCAGTTAGCCACCGATGAGCTGGCAAAGGGGATAAACGAAGAGGTGGTGCGCGCAATTTCGGCGAAGCGTAATGAGCCGG
AGTGGATGCTGGAGTTTCGTCTCAACGCCTATCGCGCATGGCTGGAGATGGAAGAACCGCACTGGTTGAAAGCGCACTAC
GACAAGCTGAATTATCAGGATTACAGCTACTACTCAGCACCATCGTGCGGTAATTGTGACGACAACTGCGCGTCTGAACC
CGGCGCGGTGCAGCAAACTGGTGCGAACGCCTTTTTAAGTAAAGAGGTGGAGGCGGCGTTTGAGCAGTTGGGCGTTCCCG
TGCGGGAAGGCAAAGAGGTGGCGGTGGATGCCATTTTCGACTCTGTTTCGGTTGCCACCACTTATCGTGAAAAACTGGCG
GAGCAGGGAATTATTTTATGTTCCTTTGGCGAGGCGATCCACGATCACCCGGAACTTGTGCGTAAATATCTCGGCACCGT
GGTGCCGGGGAATGACAACTTCTTTGCCGCACTTAATGCGGCGGTAGCCTCTGACGGAACGTTTATTTATGTGCCTAAAG
GCGTGCGCTGCCCGATGGAACTTTCCACCTATTTTCGCATTAACGCGGAAAAAACAGGGCAGTTTGAGCGCACCATTCTG
GTGGCCGACGAAGACAGCTATGTCAGTTACATTGAAGGCTGTTCCGCTCCGGTGCGTGACAGCTATCAGTTACACGCGGC
GGTGGTTGAAGTCATCATCCATAAAAACGCCGAGGTGAAATATTCCACGGTACAAAACTGGTTCCCTGGCGATAACAACA
CCGGCGGTATTCTCAACTTCGTCACCAAGCGTGCTTTGTGCGAAGGCGAAAACAGCAAAATGTCATGGACGCAATCAGAA
ACCGGGTCAGCGATTACGTGGAAATATCCCAGTTGCATTTTGCGCGGCGATAACTCCATTGGTGAGTTTTACTCAGTGGC
ACTGACCAGCGGTCATCAGCAAGCGGATACCGGCACCAAGATGATCCACATCGGTAAAAACACCAAATCGACCATTATCT
CGAAAGGGGTCTCTGCCGGACATAGTCAGAACAGTTATCGCGGCTTAGTGAAAATCATGCCGACGGCAACCAATGCGCGC
AATTTCACTCAGTGCGACTCAATGCTGATTGGCGCTAATTGTGGGGCGCATACCTTCCCGTATGTCGAATGTCGCAATAA
CAGCGCACAACTGGAGCACGAGGCAACGACATCACGTATTGGTGAAGATCAACTGTTTTACTGCCTGCAACGCGGGATCA
GCGAAGAAGACGCCATCTCGATGATTGTTAACGGTTTCTGCAAAGACGTGTTCTCAGAACTGCCGCTGGAATTTGCCGTT
GAAGCACAAAAACTCCTCGCCATCAGTCTTGAACACAGCGTCGGATAA

Upstream 100 bases:

>100_bases
ATTTCGTTCGTGAAGGACTTAATCAGATATTCAAATTTCACAACCCTAAAGCCCAGAATGAATGTGGCTGTGGCGAAAGC
TTTGGGGTATAGGCGGTACT

Downstream 100 bases:

>100_bases
GGAATAAACATGTTAAGTATTAAAGATTTACACGTCAGCGTGGAAGATAAAGCTATCCTGCGTGGATTAAGCCTCGACGT
TCGTCCCGGCGAAGTTCACG

Product: cysteine desulfurase activator complex subunit SufB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 495; Mature: 494

Protein sequence:

>495_residues
MSRNTEATDDVKTWTGGPLNYKEGFFTQLATDELAKGINEEVVRAISAKRNEPEWMLEFRLNAYRAWLEMEEPHWLKAHY
DKLNYQDYSYYSAPSCGNCDDNCASEPGAVQQTGANAFLSKEVEAAFEQLGVPVREGKEVAVDAIFDSVSVATTYREKLA
EQGIILCSFGEAIHDHPELVRKYLGTVVPGNDNFFAALNAAVASDGTFIYVPKGVRCPMELSTYFRINAEKTGQFERTIL
VADEDSYVSYIEGCSAPVRDSYQLHAAVVEVIIHKNAEVKYSTVQNWFPGDNNTGGILNFVTKRALCEGENSKMSWTQSE
TGSAITWKYPSCILRGDNSIGEFYSVALTSGHQQADTGTKMIHIGKNTKSTIISKGVSAGHSQNSYRGLVKIMPTATNAR
NFTQCDSMLIGANCGAHTFPYVECRNNSAQLEHEATTSRIGEDQLFYCLQRGISEEDAISMIVNGFCKDVFSELPLEFAV
EAQKLLAISLEHSVG

Sequences:

>Translated_495_residues
MSRNTEATDDVKTWTGGPLNYKEGFFTQLATDELAKGINEEVVRAISAKRNEPEWMLEFRLNAYRAWLEMEEPHWLKAHY
DKLNYQDYSYYSAPSCGNCDDNCASEPGAVQQTGANAFLSKEVEAAFEQLGVPVREGKEVAVDAIFDSVSVATTYREKLA
EQGIILCSFGEAIHDHPELVRKYLGTVVPGNDNFFAALNAAVASDGTFIYVPKGVRCPMELSTYFRINAEKTGQFERTIL
VADEDSYVSYIEGCSAPVRDSYQLHAAVVEVIIHKNAEVKYSTVQNWFPGDNNTGGILNFVTKRALCEGENSKMSWTQSE
TGSAITWKYPSCILRGDNSIGEFYSVALTSGHQQADTGTKMIHIGKNTKSTIISKGVSAGHSQNSYRGLVKIMPTATNAR
NFTQCDSMLIGANCGAHTFPYVECRNNSAQLEHEATTSRIGEDQLFYCLQRGISEEDAISMIVNGFCKDVFSELPLEFAV
EAQKLLAISLEHSVG
>Mature_494_residues
SRNTEATDDVKTWTGGPLNYKEGFFTQLATDELAKGINEEVVRAISAKRNEPEWMLEFRLNAYRAWLEMEEPHWLKAHYD
KLNYQDYSYYSAPSCGNCDDNCASEPGAVQQTGANAFLSKEVEAAFEQLGVPVREGKEVAVDAIFDSVSVATTYREKLAE
QGIILCSFGEAIHDHPELVRKYLGTVVPGNDNFFAALNAAVASDGTFIYVPKGVRCPMELSTYFRINAEKTGQFERTILV
ADEDSYVSYIEGCSAPVRDSYQLHAAVVEVIIHKNAEVKYSTVQNWFPGDNNTGGILNFVTKRALCEGENSKMSWTQSET
GSAITWKYPSCILRGDNSIGEFYSVALTSGHQQADTGTKMIHIGKNTKSTIISKGVSAGHSQNSYRGLVKIMPTATNARN
FTQCDSMLIGANCGAHTFPYVECRNNSAQLEHEATTSRIGEDQLFYCLQRGISEEDAISMIVNGFCKDVFSELPLEFAVE
AQKLLAISLEHSVG

Specific function: The sufBCD complex acts synergistically with sufE to stimulate the cysteine desulfurase activity of sufS. The sufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May facilitate iron uptake fro

COG id: COG0719

COG function: function code O; ABC-type transport system involved in Fe-S cluster assembly, permease component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0051 (ycf24) family [H]

Homologues:

Organism=Escherichia coli, GI87081955, Length=495, Percent_Identity=99.3939393939394, Blast_Score=1035, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010231
- InterPro:   IPR000825 [H]

Pfam domain/function: PF01458 UPF0051 [H]

EC number: NA

Molecular weight: Translated: 54711; Mature: 54579

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRNTEATDDVKTWTGGPLNYKEGFFTQLATDELAKGINEEVVRAISAKRNEPEWMLEFR
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEEH
LNAYRAWLEMEEPHWLKAHYDKLNYQDYSYYSAPSCGNCDDNCASEPGAVQQTGANAFLS
HHHHHHHEECCCCCHHHHHHHCCCCCCCCEECCCCCCCCCCCCCCCCCCCHHCCCHHHHH
KEVEAAFEQLGVPVREGKEVAVDAIFDSVSVATTYREKLAEQGIILCSFGEAIHDHPELV
HHHHHHHHHHCCCHHCCCCEEHHHHHHHHHHHHHHHHHHHHCCEEEEECCHHHCCCHHHH
RKYLGTVVPGNDNFFAALNAAVASDGTFIYVPKGVRCPMELSTYFRINAEKTGQFERTIL
HHHHCEECCCCCCEEEEEEHHHCCCCCEEEECCCCCCCCEECEEEEEECCCCCCEEEEEE
VADEDSYVSYIEGCSAPVRDSYQLHAAVVEVIIHKNAEVKYSTVQNWFPGDNNTGGILNF
EECCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEHHHCCCCCCCCCCHHHHH
VTKRALCEGENSKMSWTQSETGSAITWKYPSCILRGDNSIGEFYSVALTSGHQQADTGTK
HHHHHHHCCCCCCEEEECCCCCCEEEEECCCEEEECCCCCCHHEEEEECCCCCCCCCCCE
MIHIGKNTKSTIISKGVSAGHSQNSYRGLVKIMPTATNARNFTQCDSMLIGANCGAHTFP
EEEECCCCHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCHHHHCCEEEECCCCCCCCC
YVECRNNSAQLEHEATTSRIGEDQLFYCLQRGISEEDAISMIVNGFCKDVFSELPLEFAV
EEEECCCCCCCHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHH
EAQKLLAISLEHSVG
HHHHHHEEEECCCCC
>Mature Secondary Structure 
SRNTEATDDVKTWTGGPLNYKEGFFTQLATDELAKGINEEVVRAISAKRNEPEWMLEFR
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEEH
LNAYRAWLEMEEPHWLKAHYDKLNYQDYSYYSAPSCGNCDDNCASEPGAVQQTGANAFLS
HHHHHHHEECCCCCHHHHHHHCCCCCCCCEECCCCCCCCCCCCCCCCCCCHHCCCHHHHH
KEVEAAFEQLGVPVREGKEVAVDAIFDSVSVATTYREKLAEQGIILCSFGEAIHDHPELV
HHHHHHHHHHCCCHHCCCCEEHHHHHHHHHHHHHHHHHHHHCCEEEEECCHHHCCCHHHH
RKYLGTVVPGNDNFFAALNAAVASDGTFIYVPKGVRCPMELSTYFRINAEKTGQFERTIL
HHHHCEECCCCCCEEEEEEHHHCCCCCEEEECCCCCCCCEECEEEEEECCCCCCEEEEEE
VADEDSYVSYIEGCSAPVRDSYQLHAAVVEVIIHKNAEVKYSTVQNWFPGDNNTGGILNF
EECCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEHHHCCCCCCCCCCHHHHH
VTKRALCEGENSKMSWTQSETGSAITWKYPSCILRGDNSIGEFYSVALTSGHQQADTGTK
HHHHHHHCCCCCCEEEECCCCCCEEEEECCCEEEECCCCCCHHEEEEECCCCCCCCCCCE
MIHIGKNTKSTIISKGVSAGHSQNSYRGLVKIMPTATNARNFTQCDSMLIGANCGAHTFP
EEEECCCCHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCHHHHCCEEEECCCCCCCCC
YVECRNNSAQLEHEATTSRIGEDQLFYCLQRGISEEDAISMIVNGFCKDVFSELPLEFAV
EEEECCCCCCCHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHH
EAQKLLAISLEHSVG
HHHHHHEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 10322040 [H]