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The map label for this gene is sufA

Identifier: 218699751

GI number: 218699751

Start: 1442860

End: 1443228

Strand: Direct

Name: sufA

Synonym: ECIAI39_1374

Alternate gene names: 218699751

Gene position: 1442860-1443228 (Clockwise)

Preceding gene: 218699750

Following gene: 218699752

Centisome position: 28.11

GC content: 53.66

Gene sequence:

>369_bases
ATGGACATGCATTCAGGAACCTTTAATCCACAGGATTTCGTCTGGCAGGGCTTAACGCTGACACCCGCAGCCGCTGTCCA
CATCCGCGAGCTGGTGGCAAAGCAGCCGGGTATGGTCGGCGTGCGCTTAGGCGTGAAGCAAACGGGCTGCGCGGGCTTTG
GCTATGTGCTCGACAGTGTTAGCGAGCCGGACAAAGACGATCTGCTGTTTGAACACGACGGTGCGAAGCTGTTTGTCCCG
CTGCAAGCGATGCCGTTTATTGATGGCACGGAAGTCGATTTCGTTCGTGAAGGACTTAATCAGATATTCAAATTTCACAA
CCCTAAAGCCCAGAATGAATGTGGCTGTGGCGAAAGCTTTGGGGTATAG

Upstream 100 bases:

>100_bases
CATGTTTTACGGTAAAGCCCCTGTGTTTGCTGGGTTGAACTGATAATCATTATCACTAACATGCTGTTATACGCTGAAAG
CGATGAAGTGAGGTAAATCG

Downstream 100 bases:

>100_bases
GCGGTACTATGTCTCGTAATACTGAAGCAACTGACGATGTCAAAACCTGGACCGGCGGCCCGCTGAATTATAAAGAAGGA
TTCTTCACCCAGTTAGCCAC

Product: iron-sulfur cluster assembly scaffold protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 122; Mature: 122

Protein sequence:

>122_residues
MDMHSGTFNPQDFVWQGLTLTPAAAVHIRELVAKQPGMVGVRLGVKQTGCAGFGYVLDSVSEPDKDDLLFEHDGAKLFVP
LQAMPFIDGTEVDFVREGLNQIFKFHNPKAQNECGCGESFGV

Sequences:

>Translated_122_residues
MDMHSGTFNPQDFVWQGLTLTPAAAVHIRELVAKQPGMVGVRLGVKQTGCAGFGYVLDSVSEPDKDDLLFEHDGAKLFVP
LQAMPFIDGTEVDFVREGLNQIFKFHNPKAQNECGCGESFGV
>Mature_122_residues
MDMHSGTFNPQDFVWQGLTLTPAAAVHIRELVAKQPGMVGVRLGVKQTGCAGFGYVLDSVSEPDKDDLLFEHDGAKLFVP
LQAMPFIDGTEVDFVREGLNQIFKFHNPKAQNECGCGESFGV

Specific function: Unknown

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family [H]

Homologues:

Organism=Homo sapiens, GI52426768, Length=106, Percent_Identity=38.6792452830189, Blast_Score=89, Evalue=7e-19,
Organism=Homo sapiens, GI160420328, Length=98, Percent_Identity=37.7551020408163, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1787974, Length=122, Percent_Identity=98.3606557377049, Blast_Score=251, Evalue=7e-69,
Organism=Escherichia coli, GI1788877, Length=105, Percent_Identity=47.6190476190476, Blast_Score=111, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI193209025, Length=106, Percent_Identity=38.6792452830189, Blast_Score=85, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI25146411, Length=106, Percent_Identity=38.6792452830189, Blast_Score=85, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6323001, Length=105, Percent_Identity=40, Blast_Score=86, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24642263, Length=106, Percent_Identity=46.2264150943396, Blast_Score=103, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870
- InterPro:   IPR011298 [H]

Pfam domain/function: PF01521 Fe-S_biosyn [H]

EC number: NA

Molecular weight: Translated: 13314; Mature: 13314

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDMHSGTFNPQDFVWQGLTLTPAAAVHIRELVAKQPGMVGVRLGVKQTGCAGFGYVLDSV
CCCCCCCCCCHHHEECCCEECHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHCC
SEPDKDDLLFEHDGAKLFVPLQAMPFIDGTEVDFVREGLNQIFKFHNPKAQNECGCGESF
CCCCCCCEEEEECCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
GV
CC
>Mature Secondary Structure
MDMHSGTFNPQDFVWQGLTLTPAAAVHIRELVAKQPGMVGVRLGVKQTGCAGFGYVLDSV
CCCCCCCCCCHHHEECCCEECHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHCC
SEPDKDDLLFEHDGAKLFVPLQAMPFIDGTEVDFVREGLNQIFKFHNPKAQNECGCGESF
CCCCCCCEEEEECCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
GV
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 10322040 [H]