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The map label for this gene is yeeO

Identifier: 218699447

GI number: 218699447

Start: 1121386

End: 1123026

Strand: Direct

Name: yeeO

Synonym: ECIAI39_1061

Alternate gene names: 218699447

Gene position: 1121386-1123026 (Clockwise)

Preceding gene: 218699446

Following gene: 218699451

Centisome position: 21.85

GC content: 48.32

Gene sequence:

>1641_bases
TTGAGGCACATCTTAACGGCGAAAAATATTTTGTCAAACCCGATTTTTAAATTTCCCAACTGTTTGCCGTTTCTATCAAC
AGTTTGTTGCATTTGCAGACAATTTGTTGGCGAAAATCTTTGCAGCTTTGCTGATTCTCCCTCATCATTTGAAATGTGGT
TTCACTTTCTGCAATTAAGGTCGGCTTTGAATATCTCCTCTGCTTTACGCCAGGTTGTTCACGGCACTCGCTGGCACTCT
AAACGCAAGAGCTACAAAGTGTTGTTCTGGCGCGAGATAACCCCGCTTGCTGTTCCTATCTTCATGGAGAACGCCTGTGT
CCTGTTGATGGGGGTCCTGAGCACTTTTCTGGTCAGCTGGCTGGGAAAAGATGCGATGGCCGGCGTGGGGTTGGCGGACA
GCTTCAATATGGTCATTATGGCTTTTTTTGCAGCTATCGATCTTGGTACTACTGTCGTTGTAGCATTTAGTCTCGGTAAG
CGAGATCGACGACGAGCGAGGGTGGCGACGCGGCAGTCATTGGTGATCATGACGTTGTTTGCCGTACTGTTGGCAACGCT
AATTCATCATTTTGGCGAACAAATTATTGATTTCGTCGCGGGTGATGCCACGACAGACGTTAAAGCACTGGCGTTGACTT
ATCTGGAGCTGACCGTACTCAGTTATCCAGCAGCTGCCATCACTCTTATTGGTAGCGGGGCACTTCGTGGTGCAGGGAAT
ACGAAAATACCGCTACTGATTAACGGTAGCCTGAATATTCTTAATATTATTATTAGCGGCATATTGATTTACGGCCTTTT
CTCCTGGGCGGGACTGGGATTTGTCGGGGCTGGGTTGGGTTTAACCATTTCTCGTTATATTGGCGCAGTTGCAATTTTGT
GGGTGCTGGCGATTGGTTTTAATCCTGCGCTAAGGATTTCGTTAAAGAGCTATTTTAAACCGCTGAATTTTAGCATTATC
TGGGAAGTCATGGGGATTGGTATTCCAGCGAGTGTCGAATCAGTGTTATTTACCAGTGGTCGGTTATTAACCCAAATGTT
CGTTGCCGGGATGGGGACCAGCGTTATTGCCGGAAATTTTATCGCGTTCTCAATTGCGGCTCTTATCAACTTACCCGGAA
GTGCGCTCGGTTCTGCTTCTACGATCATTACAGGCCGAAGGTTGGGGGTAGGGCAGATAGCGCAAGCAGAGATTCAGTTG
CGGCATGTGTTCTGGCTGTCCACTCTTGGATTAACGGCCATCGCCTGGCTAACGGCTCCCTTTGCCGGGGTTATGGCATC
GTTTTACACCCAGGATCCACAGGTTAAACACGTCGTTGTGATTCTGATTTGGCTAAATGCTTTATTTATGCCTATTTGGT
CCGCCTCATGGGTGCTACCCGCTGGATTTAAAGGTGCTCGTGATGCCCGTTACGCCATGTGGGTTTCGATGTTGAGCATG
TGGTGTTGTCGGGTTGTAGTCGGTTATGTGCTGGGAATCATGCTTGGCTGGGGTGTGGTTGGTGTCTGGATGGGAATGTT
TGCCGACTGGGCTGTGCGGGCCGTGCTGTTTTACTGGCGAATGGTTACTGGACGTTGGCTATGGAAATACCCTCGATCCG
AGCCGCAAAAGTGTGAAAAAAAGCCAGTTGTGTCGGAATAA

Upstream 100 bases:

>100_bases
CGGGCTTTTCAGAAATTTGGCTCCTCTGACTGGACTCGAACCAGTGACATACGGATTAACAGTCCGCCGTTCTACCGACT
GAACTACAGAGGAATCGCTG

Downstream 100 bases:

>100_bases
ACGACAAAATGCAGATTATTTCAGCAAACGATTTCAAATTTAAAAAACAGGCTTTGACATTGTGGGTGGGCATCGCTAAT
ATTCGCCTCGTTCTCACGAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 546; Mature: 546

Protein sequence:

>546_residues
MRHILTAKNILSNPIFKFPNCLPFLSTVCCICRQFVGENLCSFADSPSSFEMWFHFLQLRSALNISSALRQVVHGTRWHS
KRKSYKVLFWREITPLAVPIFMENACVLLMGVLSTFLVSWLGKDAMAGVGLADSFNMVIMAFFAAIDLGTTVVVAFSLGK
RDRRRARVATRQSLVIMTLFAVLLATLIHHFGEQIIDFVAGDATTDVKALALTYLELTVLSYPAAAITLIGSGALRGAGN
TKIPLLINGSLNILNIIISGILIYGLFSWAGLGFVGAGLGLTISRYIGAVAILWVLAIGFNPALRISLKSYFKPLNFSII
WEVMGIGIPASVESVLFTSGRLLTQMFVAGMGTSVIAGNFIAFSIAALINLPGSALGSASTIITGRRLGVGQIAQAEIQL
RHVFWLSTLGLTAIAWLTAPFAGVMASFYTQDPQVKHVVVILIWLNALFMPIWSASWVLPAGFKGARDARYAMWVSMLSM
WCCRVVVGYVLGIMLGWGVVGVWMGMFADWAVRAVLFYWRMVTGRWLWKYPRSEPQKCEKKPVVSE

Sequences:

>Translated_546_residues
MRHILTAKNILSNPIFKFPNCLPFLSTVCCICRQFVGENLCSFADSPSSFEMWFHFLQLRSALNISSALRQVVHGTRWHS
KRKSYKVLFWREITPLAVPIFMENACVLLMGVLSTFLVSWLGKDAMAGVGLADSFNMVIMAFFAAIDLGTTVVVAFSLGK
RDRRRARVATRQSLVIMTLFAVLLATLIHHFGEQIIDFVAGDATTDVKALALTYLELTVLSYPAAAITLIGSGALRGAGN
TKIPLLINGSLNILNIIISGILIYGLFSWAGLGFVGAGLGLTISRYIGAVAILWVLAIGFNPALRISLKSYFKPLNFSII
WEVMGIGIPASVESVLFTSGRLLTQMFVAGMGTSVIAGNFIAFSIAALINLPGSALGSASTIITGRRLGVGQIAQAEIQL
RHVFWLSTLGLTAIAWLTAPFAGVMASFYTQDPQVKHVVVILIWLNALFMPIWSASWVLPAGFKGARDARYAMWVSMLSM
WCCRVVVGYVLGIMLGWGVVGVWMGMFADWAVRAVLFYWRMVTGRWLWKYPRSEPQKCEKKPVVSE
>Mature_546_residues
MRHILTAKNILSNPIFKFPNCLPFLSTVCCICRQFVGENLCSFADSPSSFEMWFHFLQLRSALNISSALRQVVHGTRWHS
KRKSYKVLFWREITPLAVPIFMENACVLLMGVLSTFLVSWLGKDAMAGVGLADSFNMVIMAFFAAIDLGTTVVVAFSLGK
RDRRRARVATRQSLVIMTLFAVLLATLIHHFGEQIIDFVAGDATTDVKALALTYLELTVLSYPAAAITLIGSGALRGAGN
TKIPLLINGSLNILNIIISGILIYGLFSWAGLGFVGAGLGLTISRYIGAVAILWVLAIGFNPALRISLKSYFKPLNFSII
WEVMGIGIPASVESVLFTSGRLLTQMFVAGMGTSVIAGNFIAFSIAALINLPGSALGSASTIITGRRLGVGQIAQAEIQL
RHVFWLSTLGLTAIAWLTAPFAGVMASFYTQDPQVKHVVVILIWLNALFMPIWSASWVLPAGFKGARDARYAMWVSMLSM
WCCRVVVGYVLGIMLGWGVVGVWMGMFADWAVRAVLFYWRMVTGRWLWKYPRSEPQKCEKKPVVSE

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=495, Percent_Identity=98.989898989899, Blast_Score=973, Evalue=0.0,
Organism=Escherichia coli, GI48994890, Length=461, Percent_Identity=23.4273318872017, Blast_Score=73, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 59934; Mature: 59934

Theoretical pI: Translated: 10.31; Mature: 10.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHILTAKNILSNPIFKFPNCLPFLSTVCCICRQFVGENLCSFADSPSSFEMWFHFLQLR
CCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
SALNISSALRQVVHGTRWHSKRKSYKVLFWREITPLAVPIFMENACVLLMGVLSTFLVSW
HHHCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LGKDAMAGVGLADSFNMVIMAFFAAIDLGTTVVVAFSLGKRDRRRARVATRQSLVIMTLF
HCCHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHEECCCCHHHHHHHHHHHHHHHHHHHH
AVLLATLIHHFGEQIIDFVAGDATTDVKALALTYLELTVLSYPAAAITLIGSGALRGAGN
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHEECCCCCCCCCC
TKIPLLINGSLNILNIIISGILIYGLFSWAGLGFVGAGLGLTISRYIGAVAILWVLAIGF
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC
NPALRISLKSYFKPLNFSIIWEVMGIGIPASVESVLFTSGRLLTQMFVAGMGTSVIAGNF
CCCEEEEHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHH
IAFSIAALINLPGSALGSASTIITGRRLGVGQIAQAEIQLRHVFWLSTLGLTAIAWLTAP
HHHHHHHHHHCCCCCCCCCHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FAGVMASFYTQDPQVKHVVVILIWLNALFMPIWSASWVLPAGFKGARDARYAMWVSMLSM
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHH
WCCRVVVGYVLGIMLGWGVVGVWMGMFADWAVRAVLFYWRMVTGRWLWKYPRSEPQKCEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCHHHCC
KPVVSE
CCCCCC
>Mature Secondary Structure
MRHILTAKNILSNPIFKFPNCLPFLSTVCCICRQFVGENLCSFADSPSSFEMWFHFLQLR
CCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
SALNISSALRQVVHGTRWHSKRKSYKVLFWREITPLAVPIFMENACVLLMGVLSTFLVSW
HHHCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LGKDAMAGVGLADSFNMVIMAFFAAIDLGTTVVVAFSLGKRDRRRARVATRQSLVIMTLF
HCCHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHEECCCCHHHHHHHHHHHHHHHHHHHH
AVLLATLIHHFGEQIIDFVAGDATTDVKALALTYLELTVLSYPAAAITLIGSGALRGAGN
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHEECCCCCCCCCC
TKIPLLINGSLNILNIIISGILIYGLFSWAGLGFVGAGLGLTISRYIGAVAILWVLAIGF
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC
NPALRISLKSYFKPLNFSIIWEVMGIGIPASVESVLFTSGRLLTQMFVAGMGTSVIAGNF
CCCEEEEHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHH
IAFSIAALINLPGSALGSASTIITGRRLGVGQIAQAEIQLRHVFWLSTLGLTAIAWLTAP
HHHHHHHHHHCCCCCCCCCHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FAGVMASFYTQDPQVKHVVVILIWLNALFMPIWSASWVLPAGFKGARDARYAMWVSMLSM
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHH
WCCRVVVGYVLGIMLGWGVVGVWMGMFADWAVRAVLFYWRMVTGRWLWKYPRSEPQKCEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCHHHCC
KPVVSE
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]