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The map label for this gene is mlrA

Identifier: 218699264

GI number: 218699264

Start: 918261

End: 918908

Strand: Reverse

Name: mlrA

Synonym: ECIAI39_0870

Alternate gene names: 218699264

Gene position: 918908-918261 (Counterclockwise)

Preceding gene: 218699265

Following gene: 218699263

Centisome position: 17.91

GC content: 53.4

Gene sequence:

>648_bases
TTGCTGAAACCGCAACGGACAGACGGCGGTCATCGGCTGTTCAACGATGCCGATATTGACCGGATCCGCGAGATCAAACG
CTGGATCGACAACGGCGTGCAGGTCAGCAAAGTAAAAATGCTGCTCAGTAATGAAAATGTTGATGTGCAGAACGGCTGGC
GCGATCAGCAAGAAACATTACTGACTTACCTGCAAAGCGGCAATCTGCATAGCCTGCGAACGTGGATCAAAGAGCGCGGT
CAGGATTACCCCGCCCAGACACTCACCACACATCTGTTTATTCCTCTGCGCCGACGACTTCAGTGTCAACAACCGACTCT
CCAGGCGCTGCTGGCGATCCTCGACGGCGTACTGATCAACTACATCGCCATCTGTCTGGCTTCGGCACGTAAAAAACAGG
GTAAAGATGCGCTGGTGGTTGGCTGGAATATTCACGATACCACCCGTCTGTGGCTGGAGGGCTGGATTGCCAGTCAACAA
GGATGGCGCATTGATGTCCTCGCCCACTCGCTCAATCAACTACGCCCTGAACTGTTCGAAGGCCGTACATTGCTGGTGTG
GTGCGGTGAAAATCGAACCTCTGCCCAACAGCAGCAACTCACCAGTTGGCAGGAACAAGGCCATGATATTTTCCCACTCG
GCATTTAA

Upstream 100 bases:

>100_bases
GTATGCCCCATAAGAAAGTTGGGTAAAATAAAAACTTGCAAAATCAGTTAGTTTACCCTTAATCCCTGTCACGTTACGCG
CGTGGCAGAGGCGTTACGGA

Downstream 100 bases:

>100_bases
TGATTCGTTAACAAATGCGCTTTACTGTACAATCCTTTCGTTAACATAAGGAGTGCATTATGCGCATAGCTAAAATTGGG
GTCATCGCCCTGTTCCTGTT

Product: DNA-binding transcriptional regulator

Products: NA

Alternate protein names: MerR-like regulator A [H]

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MLKPQRTDGGHRLFNDADIDRIREIKRWIDNGVQVSKVKMLLSNENVDVQNGWRDQQETLLTYLQSGNLHSLRTWIKERG
QDYPAQTLTTHLFIPLRRRLQCQQPTLQALLAILDGVLINYIAICLASARKKQGKDALVVGWNIHDTTRLWLEGWIASQQ
GWRIDVLAHSLNQLRPELFEGRTLLVWCGENRTSAQQQQLTSWQEQGHDIFPLGI

Sequences:

>Translated_215_residues
MLKPQRTDGGHRLFNDADIDRIREIKRWIDNGVQVSKVKMLLSNENVDVQNGWRDQQETLLTYLQSGNLHSLRTWIKERG
QDYPAQTLTTHLFIPLRRRLQCQQPTLQALLAILDGVLINYIAICLASARKKQGKDALVVGWNIHDTTRLWLEGWIASQQ
GWRIDVLAHSLNQLRPELFEGRTLLVWCGENRTSAQQQQLTSWQEQGHDIFPLGI
>Mature_215_residues
MLKPQRTDGGHRLFNDADIDRIREIKRWIDNGVQVSKVKMLLSNENVDVQNGWRDQQETLLTYLQSGNLHSLRTWIKERG
QDYPAQTLTTHLFIPLRRRLQCQQPTLQALLAILDGVLINYIAICLASARKKQGKDALVVGWNIHDTTRLWLEGWIASQQ
GWRIDVLAHSLNQLRPELFEGRTLLVWCGENRTSAQQQQLTSWQEQGHDIFPLGI

Specific function: Transcriptional activator of the csg genes required for production of the curli (AgF) [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788448, Length=215, Percent_Identity=99.0697674418605, Blast_Score=433, Evalue=1e-123,
Organism=Escherichia coli, GI1787409, Length=211, Percent_Identity=44.0758293838863, Blast_Score=194, Evalue=5e-51,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551 [H]

Pfam domain/function: PF00376 MerR [H]

EC number: NA

Molecular weight: Translated: 24868; Mature: 24868

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKPQRTDGGHRLFNDADIDRIREIKRWIDNGVQVSKVKMLLSNENVDVQNGWRDQQETL
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCHHHHHH
LTYLQSGNLHSLRTWIKERGQDYPAQTLTTHLFIPLRRRLQCQQPTLQALLAILDGVLIN
HHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
YIAICLASARKKQGKDALVVGWNIHDTTRLWLEGWIASQQGWRIDVLAHSLNQLRPELFE
HHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCHHHHC
GRTLLVWCGENRTSAQQQQLTSWQEQGHDIFPLGI
CCEEEEEECCCCCHHHHHHHHHHHHCCCCEECCCC
>Mature Secondary Structure
MLKPQRTDGGHRLFNDADIDRIREIKRWIDNGVQVSKVKMLLSNENVDVQNGWRDQQETL
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCHHHHHH
LTYLQSGNLHSLRTWIKERGQDYPAQTLTTHLFIPLRRRLQCQQPTLQALLAILDGVLIN
HHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
YIAICLASARKKQGKDALVVGWNIHDTTRLWLEGWIASQQGWRIDVLAHSLNQLRPELFE
HHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCHHHHC
GRTLLVWCGENRTSAQQQQLTSWQEQGHDIFPLGI
CCEEEEEECCCCCHHHHHHHHHHHHCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11489123; 9278503 [H]