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The map label for this gene is tauD

Identifier: 218698727

GI number: 218698727

Start: 345237

End: 346364

Strand: Reverse

Name: tauD

Synonym: ECIAI39_0313

Alternate gene names: 218698727

Gene position: 346364-345237 (Counterclockwise)

Preceding gene: 218698728

Following gene: 218698723

Centisome position: 6.75

GC content: 54.79

Gene sequence:

>1128_bases
GTGCTGTGGTTTGTTATTTTGCCCGGTGCGCTGCCGGAAATTCTCACCGGATTACGCATTGGTCTGGGTGTGGGCTGGTC
TACCCTGGTGGCGGCGGAGCTGATTGCCGCGACGCGCGGTTTGGGTTTTATGGTCCAGTCAGCGGGTGAATTTCTCGCGA
CTGACGTGGTGCTGGCGGGGATCGCGGTGATTGCGATTATCGCCTTTCTTTTAGAACTGGGTCTGCGCGCGCTACAGCGC
CGCCTGACGCGCCCGTTAAGCGATAATCAGTTTGAACAGCTTTACCATGCGGTGCTGCGCCATCAGGTGGTGTTTCTGCG
CGATCAAGCTATTACGCCGCAGCAGCAACGCGCGCTGGCCCAACGTTTTGGCGAACTGCATATTCATCCTGTTTACCCTC
ATGCCGAAGGGGTTGACGAGATCATCGTCCTGGATACTCATAACGATAATCCGCCGGATAACGACAACTGGCATACCGAT
GTGACATTTATTGAAACGCCACCCGCAGGGGCGATTCTGGCGGCAAAAGAGTTACCCTCGACCGGCGGTGATACGCTCTG
GACCAGCGGTATTGCGGCCTATGAGGCGCTCTCTGTTCCCTTCCGCCAGCTGCTGAGCGGGCTGCGTGCGGAGCATGATT
TCCGTAAATCGTTCCCGGAATACAAATACCGCAAAACCGAAGAGGAGCATCAACGCTGGCGCGAGGCGGTCGCGAAAAAT
CCTCCATTGTTACACCCTGTGGTGCGAACGCATCCGGTGAGCGGTAAACAGGCGCTGTTTGTGAATGAAGGCTTTACCAC
GCGAATTGTTGATGTCAGCGAGAAAGAGAGCGAAGCCTTGTTAAGTTTTTTATTTGCCCATATCACCAAACCGGAGTTTC
AGGTGCGCTGGCGCTGGCAGCCAAATGATATCGCGATTTGGGATAACCGCGTGACTCAGCACTATGCCAATGCGGATTAC
CTGCCACTGAACCGCCCCGGGTTTCCTGGAGAGTGTTTTATCTGTGAACTCAGGCTGCCAGATCATCGTTTCCGATGGAA
GCATAATAAGCTTTTTCTGCTTCTGCCGGAGGAGTATGGCCCAGCCTTTCCAGCAATCGTCGATTGTTATACCAGTCCAC
CCACGTGA

Upstream 100 bases:

>100_bases
GATTTTTGCACCGGTGGCGATGTCGGCGCTGGCGGGGGTGAAAAGCGCGTAGCAGGTTCGCATTCGTGCCGCCCAGTCGC
TGGGTGCCAGCCGTGCGCAG

Downstream 100 bases:

>100_bases
GTGTGGCCAGTTCCACTTCTGCACGGTTTTTCCAGCTCTTACGGTGTATTACCTCCGCTTTGTAAAGGCCATTGATGCTC
TCCGCCATCGCGTTGTCATA

Product: taurine dioxygenase, 2-oxoglutarate-dependent

Products: NA

Alternate protein names: 2-aminoethanesulfonate dioxygenase; Sulfate starvation-induced protein 3; SSI3 [H]

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MLWFVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFMVQSAGEFLATDVVLAGIAVIAIIAFLLELGLRALQR
RLTRPLSDNQFEQLYHAVLRHQVVFLRDQAITPQQQRALAQRFGELHIHPVYPHAEGVDEIIVLDTHNDNPPDNDNWHTD
VTFIETPPAGAILAAKELPSTGGDTLWTSGIAAYEALSVPFRQLLSGLRAEHDFRKSFPEYKYRKTEEEHQRWREAVAKN
PPLLHPVVRTHPVSGKQALFVNEGFTTRIVDVSEKESEALLSFLFAHITKPEFQVRWRWQPNDIAIWDNRVTQHYANADY
LPLNRPGFPGECFICELRLPDHRFRWKHNKLFLLLPEEYGPAFPAIVDCYTSPPT

Sequences:

>Translated_375_residues
MLWFVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFMVQSAGEFLATDVVLAGIAVIAIIAFLLELGLRALQR
RLTRPLSDNQFEQLYHAVLRHQVVFLRDQAITPQQQRALAQRFGELHIHPVYPHAEGVDEIIVLDTHNDNPPDNDNWHTD
VTFIETPPAGAILAAKELPSTGGDTLWTSGIAAYEALSVPFRQLLSGLRAEHDFRKSFPEYKYRKTEEEHQRWREAVAKN
PPLLHPVVRTHPVSGKQALFVNEGFTTRIVDVSEKESEALLSFLFAHITKPEFQVRWRWQPNDIAIWDNRVTQHYANADY
LPLNRPGFPGECFICELRLPDHRFRWKHNKLFLLLPEEYGPAFPAIVDCYTSPPT
>Mature_375_residues
MLWFVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFMVQSAGEFLATDVVLAGIAVIAIIAFLLELGLRALQR
RLTRPLSDNQFEQLYHAVLRHQVVFLRDQAITPQQQRALAQRFGELHIHPVYPHAEGVDEIIVLDTHNDNPPDNDNWHTD
VTFIETPPAGAILAAKELPSTGGDTLWTSGIAAYEALSVPFRQLLSGLRAEHDFRKSFPEYKYRKTEEEHQRWREAVAKN
PPLLHPVVRTHPVSGKQALFVNEGFTTRIVDVSEKESEALLSFLFAHITKPEFQVRWRWQPNDIAIWDNRVTQHYANADY
LPLNRPGFPGECFICELRLPDHRFRWKHNKLFLLLPEEYGPAFPAIVDCYTSPPT

Specific function: Catalyzes the conversion of taurine and alpha ketoglutarate to sulfite, aminoacetaldehyde and succinate. Required for the utilization of taurine (2-aminoethanesulfonic acid) as an alternative sulfur source. Pentane-sulfonic acid, 3- (N-morpholino)propanes

COG id: COG2175

COG function: function code Q; Probable taurine catabolism dioxygenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tfdA dioxygenase family [H]

Homologues:

Organism=Escherichia coli, GI1786565, Length=244, Percent_Identity=99.1803278688525, Blast_Score=500, Evalue=1e-143,
Organism=Escherichia coli, GI1786564, Length=83, Percent_Identity=98.7951807228916, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI87081802, Length=80, Percent_Identity=45, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6322971, Length=285, Percent_Identity=30.8771929824561, Blast_Score=131, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003819 [H]

Pfam domain/function: PF02668 TauD [H]

EC number: =1.14.11.17 [H]

Molecular weight: Translated: 42466; Mature: 42466

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLWFVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFMVQSAGEFLATDVVLAG
CEEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
IAVIAIIAFLLELGLRALQRRLTRPLSDNQFEQLYHAVLRHQVVFLRDQAITPQQQRALA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHEEEEECCCCCHHHHHHHH
QRFGELHIHPVYPHAEGVDEIIVLDTHNDNPPDNDNWHTDVTFIETPPAGAILAAKELPS
HHHCCEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCEEEEEEECCCCCCEEEHHHCCC
TGGDTLWTSGIAAYEALSVPFRQLLSGLRAEHDFRKSFPEYKYRKTEEEHQRWREAVAKN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHCC
PPLLHPVVRTHPVSGKQALFVNEGFTTRIVDVSEKESEALLSFLFAHITKPEFQVRWRWQ
CCCCCHHHHCCCCCCCEEEEEECCCEEEEEECCCHHHHHHHHHHHHHHCCCCEEEEEEEC
PNDIAIWDNRVTQHYANADYLPLNRPGFPGECFICELRLPDHRFRWKHNKLFLLLPEEYG
CCCEEEECCHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEECCEEEEEEEHHCC
PAFPAIVDCYTSPPT
CCCCHHHCCCCCCCC
>Mature Secondary Structure
MLWFVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFMVQSAGEFLATDVVLAG
CEEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
IAVIAIIAFLLELGLRALQRRLTRPLSDNQFEQLYHAVLRHQVVFLRDQAITPQQQRALA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHEEEEECCCCCHHHHHHHH
QRFGELHIHPVYPHAEGVDEIIVLDTHNDNPPDNDNWHTDVTFIETPPAGAILAAKELPS
HHHCCEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCEEEEEEECCCCCCEEEHHHCCC
TGGDTLWTSGIAAYEALSVPFRQLLSGLRAEHDFRKSFPEYKYRKTEEEHQRWREAVAKN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHCC
PPLLHPVVRTHPVSGKQALFVNEGFTTRIVDVSEKESEALLSFLFAHITKPEFQVRWRWQ
CCCCCHHHHCCCCCCCEEEEEECCCEEEEEECCCHHHHHHHHHHHHHHCCCCEEEEEEEC
PNDIAIWDNRVTQHYANADYLPLNRPGFPGECFICELRLPDHRFRWKHNKLFLLLPEEYG
CCCEEEECCHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEECCEEEEEEEHHCC
PAFPAIVDCYTSPPT
CCCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8808933; 9278503; 2656410; 8774726; 7984428; 9287300; 11955067 [H]