| Definition | Escherichia coli 55989, complete genome. |
|---|---|
| Accession | NC_011748 |
| Length | 5,154,862 |
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The map label for this gene is frlA
Identifier: 218697051
GI number: 218697051
Start: 3834443
End: 3835780
Strand: Direct
Name: frlA
Synonym: EC55989_3776
Alternate gene names: 218697051
Gene position: 3834443-3835780 (Clockwise)
Preceding gene: 218697050
Following gene: 218697052
Centisome position: 74.38
GC content: 54.63
Gene sequence:
>1338_bases ATGGGAAGCCAGGAACTCCAACGCAAGCTCGGATTTTGGGCCGTTCTTGCAATCGCCGTCGGGACAACCGTCGGCTCCGG TATTTTTGTATCTGTGGGTGAAGTGGCAAAAGCAGCGGGCACGCCGTGGCTTACGGTGCTCGCGTTTGTCATTGGCGGGT TAATTGTGATCCCGCAAATGTGCGTCTATGCGGAACTATCCACCGCTTATCCGGAAAATGGCGCAGATTATGTTTATCTG AAAAATGCCGGAAGCCGACCGCTGGCTTTCCTCTCCGGCTGGGCCAGCTTCTGGGCCAACGATGCGCCGTCATTGTCGAT TATGGCGCTGGCGATTGTCAGCAATCTTGGCTTTTTAACGCCTATCGATCCGTTGCTCGGTAAATTTATCGCCGCCGGAT TAATTATCGCCTTTATGTTGCTACACCTGCGCTCCGTTGAAGGCGGCGCAGCGTTTCAGACGCTAATTACCATCGCCAAA ATTATCCCGTTCACTATCGTCATTGGCCTTGGGATCTTCTGGTTTAAAGCGGAGAATTTTGCCGCCCCTACCACCACTGC GATTGGCGCAACGGGCAGCTTTATGGCGCTGCTGGCGGGGATCTCTGCCACCAGTTGGTCGTATACCGGCATGGCCTCTA TCTGTTATATGACCGGCGAAATTAAAAACCCCGGAAAAACCATGCCACGAGCGCTGATTGGTTCCTGTCTGCTGGTTCTG GTGCTCTACACCCTGCTGGCGCTGGTGATTTCCGGCCTGATGCCCTTCGACAAACTCGCCAATTCTGAAACGCCGATTTC CGACGCCCTGACCTGGATCCCCGCACTCGGCAGCACCGCTGGGATCTTTGTTGCCATCACGGCGATGATCGTCATTCTTG GTTCGCTTTCCAGCTGCGTGATGTACCAGCCGCGGCTGGAATACGCGATGGCGAAAGACAACCTGTTCTTTAAATGCTTC GGCCATGTGCATCCGAAATACAACACGCCGGATGTCTCCATCATCCTGCAAGGGGCGCTGGGGATCTTCTTCATCTTCGT TTCCGATCTCACCAGCCTGCTGGGTTATTTCACCCTGGTGATGTGTTTCAAAAATACCCTCACCTTCGGCTCCATCATCT GGTGTCGTAAACGCGACGATTACAAACCGCTGTGGCGTACTCCGGCTTTCGGGCTGATGACCACCCTCGCCATTGCGTCA AGCCTCATTCTGGTCGCCTCAACCTTTGTCTGGGCACCGATTCCCGGCCTTATCTGCGCCGTCATCGTTATTGCTACTGG TCTGCCTGCTTACGCCTTCTGGGCGAAGCGTAGCCGCCAGCTCAACGCTTTGTCGTAA
Upstream 100 bases:
>100_bases AACATCATATGTTGTTATATTCATCATGCATTGTCATGTTACCTTTTAAATGACTGCAAACTCTCCCCTACAACGTATTG GACAAGAAAAAGGTATCGCT
Downstream 100 bases:
>100_bases TGTTATCTGGAGAAAATAAAATGTTGGATATTGATAAAAGCACCGTGGACTTTCTGGTCACCGAAAATATGGTTCAGGAA GTGGAAAAAGTTCTCAGCCA
Product: putative fructoselysine transporter
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 445; Mature: 444
Protein sequence:
>445_residues MGSQELQRKLGFWAVLAIAVGTTVGSGIFVSVGEVAKAAGTPWLTVLAFVIGGLIVIPQMCVYAELSTAYPENGADYVYL KNAGSRPLAFLSGWASFWANDAPSLSIMALAIVSNLGFLTPIDPLLGKFIAAGLIIAFMLLHLRSVEGGAAFQTLITIAK IIPFTIVIGLGIFWFKAENFAAPTTTAIGATGSFMALLAGISATSWSYTGMASICYMTGEIKNPGKTMPRALIGSCLLVL VLYTLLALVISGLMPFDKLANSETPISDALTWIPALGSTAGIFVAITAMIVILGSLSSCVMYQPRLEYAMAKDNLFFKCF GHVHPKYNTPDVSIILQGALGIFFIFVSDLTSLLGYFTLVMCFKNTLTFGSIIWCRKRDDYKPLWRTPAFGLMTTLAIAS SLILVASTFVWAPIPGLICAVIVIATGLPAYAFWAKRSRQLNALS
Sequences:
>Translated_445_residues MGSQELQRKLGFWAVLAIAVGTTVGSGIFVSVGEVAKAAGTPWLTVLAFVIGGLIVIPQMCVYAELSTAYPENGADYVYL KNAGSRPLAFLSGWASFWANDAPSLSIMALAIVSNLGFLTPIDPLLGKFIAAGLIIAFMLLHLRSVEGGAAFQTLITIAK IIPFTIVIGLGIFWFKAENFAAPTTTAIGATGSFMALLAGISATSWSYTGMASICYMTGEIKNPGKTMPRALIGSCLLVL VLYTLLALVISGLMPFDKLANSETPISDALTWIPALGSTAGIFVAITAMIVILGSLSSCVMYQPRLEYAMAKDNLFFKCF GHVHPKYNTPDVSIILQGALGIFFIFVSDLTSLLGYFTLVMCFKNTLTFGSIIWCRKRDDYKPLWRTPAFGLMTTLAIAS SLILVASTFVWAPIPGLICAVIVIATGLPAYAFWAKRSRQLNALS >Mature_444_residues GSQELQRKLGFWAVLAIAVGTTVGSGIFVSVGEVAKAAGTPWLTVLAFVIGGLIVIPQMCVYAELSTAYPENGADYVYLK NAGSRPLAFLSGWASFWANDAPSLSIMALAIVSNLGFLTPIDPLLGKFIAAGLIIAFMLLHLRSVEGGAAFQTLITIAKI IPFTIVIGLGIFWFKAENFAAPTTTAIGATGSFMALLAGISATSWSYTGMASICYMTGEIKNPGKTMPRALIGSCLLVLV LYTLLALVISGLMPFDKLANSETPISDALTWIPALGSTAGIFVAITAMIVILGSLSSCVMYQPRLEYAMAKDNLFFKCFG HVHPKYNTPDVSIILQGALGIFFIFVSDLTSLLGYFTLVMCFKNTLTFGSIIWCRKRDDYKPLWRTPAFGLMTTLAIASS LILVASTFVWAPIPGLICAVIVIATGLPAYAFWAKRSRQLNALS
Specific function: May be involved in fructoselysine transport [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]
Homologues:
Organism=Homo sapiens, GI187423910, Length=443, Percent_Identity=26.86230248307, Blast_Score=100, Evalue=5e-21, Organism=Homo sapiens, GI7657591, Length=443, Percent_Identity=26.86230248307, Blast_Score=100, Evalue=5e-21, Organism=Homo sapiens, GI71979932, Length=467, Percent_Identity=26.1241970021413, Blast_Score=95, Evalue=1e-19, Organism=Homo sapiens, GI115648063, Length=391, Percent_Identity=22.5063938618926, Blast_Score=95, Evalue=1e-19, Organism=Homo sapiens, GI115648022, Length=391, Percent_Identity=22.5063938618926, Blast_Score=95, Evalue=1e-19, Organism=Homo sapiens, GI186910308, Length=441, Percent_Identity=23.5827664399093, Blast_Score=95, Evalue=2e-19, Organism=Homo sapiens, GI186910306, Length=441, Percent_Identity=23.5827664399093, Blast_Score=95, Evalue=2e-19, Organism=Homo sapiens, GI186910304, Length=441, Percent_Identity=23.5827664399093, Blast_Score=95, Evalue=2e-19, Organism=Homo sapiens, GI33286428, Length=460, Percent_Identity=24.1304347826087, Blast_Score=90, Evalue=3e-18, Organism=Homo sapiens, GI110347453, Length=352, Percent_Identity=27.2727272727273, Blast_Score=85, Evalue=1e-16, Organism=Homo sapiens, GI7657683, Length=398, Percent_Identity=25.6281407035176, Blast_Score=82, Evalue=7e-16, Organism=Homo sapiens, GI181337167, Length=354, Percent_Identity=24.2937853107345, Blast_Score=76, Evalue=7e-14, Organism=Homo sapiens, GI4507047, Length=166, Percent_Identity=27.710843373494, Blast_Score=73, Evalue=6e-13, Organism=Homo sapiens, GI258614005, Length=182, Percent_Identity=27.4725274725275, Blast_Score=70, Evalue=3e-12, Organism=Homo sapiens, GI258614003, Length=182, Percent_Identity=27.4725274725275, Blast_Score=70, Evalue=4e-12, Organism=Homo sapiens, GI9790235, Length=457, Percent_Identity=22.3194748358862, Blast_Score=68, Evalue=2e-11, Organism=Homo sapiens, GI114326544, Length=192, Percent_Identity=23.4375, Blast_Score=67, Evalue=3e-11, Organism=Homo sapiens, GI114326550, Length=192, Percent_Identity=23.4375, Blast_Score=67, Evalue=3e-11, Organism=Escherichia coli, GI87082250, Length=445, Percent_Identity=100, Blast_Score=887, Evalue=0.0, Organism=Escherichia coli, GI2367353, Length=349, Percent_Identity=29.2263610315186, Blast_Score=110, Evalue=2e-25, Organism=Escherichia coli, GI87082023, Length=397, Percent_Identity=26.448362720403, Blast_Score=82, Evalue=5e-17, Organism=Escherichia coli, GI1788480, Length=272, Percent_Identity=27.2058823529412, Blast_Score=72, Evalue=8e-14, Organism=Escherichia coli, GI1790575, Length=324, Percent_Identity=27.1604938271605, Blast_Score=71, Evalue=1e-13, Organism=Escherichia coli, GI87081708, Length=350, Percent_Identity=24, Blast_Score=71, Evalue=1e-13, Organism=Escherichia coli, GI87081869, Length=403, Percent_Identity=22.8287841191067, Blast_Score=69, Evalue=8e-13, Organism=Escherichia coli, GI48994972, Length=324, Percent_Identity=28.0864197530864, Blast_Score=64, Evalue=1e-11, Organism=Caenorhabditis elegans, GI71995388, Length=389, Percent_Identity=27.5064267352185, Blast_Score=118, Evalue=5e-27, Organism=Caenorhabditis elegans, GI71995382, Length=389, Percent_Identity=27.5064267352185, Blast_Score=118, Evalue=6e-27, Organism=Caenorhabditis elegans, GI71993915, Length=388, Percent_Identity=24.7422680412371, Blast_Score=110, Evalue=1e-24, Organism=Caenorhabditis elegans, GI71982612, Length=418, Percent_Identity=24.8803827751196, Blast_Score=109, Evalue=3e-24, Organism=Caenorhabditis elegans, GI71982608, Length=418, Percent_Identity=24.8803827751196, Blast_Score=109, Evalue=3e-24, Organism=Caenorhabditis elegans, GI71990446, Length=426, Percent_Identity=24.6478873239437, Blast_Score=94, Evalue=2e-19, Organism=Caenorhabditis elegans, GI32566699, Length=341, Percent_Identity=23.4604105571848, Blast_Score=91, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17532491, Length=404, Percent_Identity=22.7722772277228, Blast_Score=90, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17540018, Length=398, Percent_Identity=25.6281407035176, Blast_Score=82, Evalue=8e-16, Organism=Caenorhabditis elegans, GI193208714, Length=391, Percent_Identity=23.7851662404092, Blast_Score=79, Evalue=4e-15, Organism=Caenorhabditis elegans, GI32566695, Length=391, Percent_Identity=23.7851662404092, Blast_Score=79, Evalue=4e-15, Organism=Caenorhabditis elegans, GI71982623, Length=272, Percent_Identity=24.6323529411765, Blast_Score=79, Evalue=6e-15, Organism=Caenorhabditis elegans, GI17531343, Length=402, Percent_Identity=23.3830845771144, Blast_Score=79, Evalue=7e-15, Organism=Caenorhabditis elegans, GI17533459, Length=399, Percent_Identity=23.0576441102757, Blast_Score=75, Evalue=7e-14, Organism=Caenorhabditis elegans, GI17568033, Length=347, Percent_Identity=25.3602305475504, Blast_Score=71, Evalue=1e-12, Organism=Saccharomyces cerevisiae, GI6321492, Length=356, Percent_Identity=23.5955056179775, Blast_Score=79, Evalue=2e-15, Organism=Drosophila melanogaster, GI24667468, Length=409, Percent_Identity=25.9168704156479, Blast_Score=110, Evalue=2e-24, Organism=Drosophila melanogaster, GI21357367, Length=425, Percent_Identity=26.1176470588235, Blast_Score=102, Evalue=4e-22, Organism=Drosophila melanogaster, GI24641995, Length=366, Percent_Identity=26.2295081967213, Blast_Score=102, Evalue=5e-22, Organism=Drosophila melanogaster, GI24641993, Length=366, Percent_Identity=26.2295081967213, Blast_Score=101, Evalue=8e-22, Organism=Drosophila melanogaster, GI221331183, Length=404, Percent_Identity=25, Blast_Score=99, Evalue=8e-21, Organism=Drosophila melanogaster, GI17647653, Length=404, Percent_Identity=25, Blast_Score=99, Evalue=8e-21, Organism=Drosophila melanogaster, GI24664379, Length=404, Percent_Identity=25, Blast_Score=99, Evalue=8e-21, Organism=Drosophila melanogaster, GI24651635, Length=366, Percent_Identity=25.1366120218579, Blast_Score=98, Evalue=9e-21, Organism=Drosophila melanogaster, GI24651633, Length=366, Percent_Identity=25.1366120218579, Blast_Score=98, Evalue=9e-21, Organism=Drosophila melanogaster, GI24666159, Length=432, Percent_Identity=23.3796296296296, Blast_Score=92, Evalue=6e-19, Organism=Drosophila melanogaster, GI221512776, Length=432, Percent_Identity=23.3796296296296, Blast_Score=92, Evalue=7e-19, Organism=Drosophila melanogaster, GI45550968, Length=453, Percent_Identity=24.5033112582781, Blast_Score=89, Evalue=6e-18, Organism=Drosophila melanogaster, GI19921172, Length=453, Percent_Identity=24.5033112582781, Blast_Score=89, Evalue=6e-18, Organism=Drosophila melanogaster, GI281366235, Length=353, Percent_Identity=25.4957507082153, Blast_Score=86, Evalue=6e-17, Organism=Drosophila melanogaster, GI116007820, Length=353, Percent_Identity=25.4957507082153, Blast_Score=86, Evalue=6e-17, Organism=Drosophila melanogaster, GI24668806, Length=404, Percent_Identity=23.019801980198, Blast_Score=82, Evalue=6e-16, Organism=Drosophila melanogaster, GI21356285, Length=404, Percent_Identity=23.019801980198, Blast_Score=82, Evalue=6e-16, Organism=Drosophila melanogaster, GI24668802, Length=404, Percent_Identity=23.019801980198, Blast_Score=82, Evalue=6e-16, Organism=Drosophila melanogaster, GI116007818, Length=355, Percent_Identity=25.6338028169014, Blast_Score=79, Evalue=9e-15, Organism=Drosophila melanogaster, GI85725152, Length=355, Percent_Identity=25.6338028169014, Blast_Score=79, Evalue=9e-15, Organism=Drosophila melanogaster, GI161077963, Length=364, Percent_Identity=22.8021978021978, Blast_Score=70, Evalue=3e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR004841 - InterPro: IPR002293 [H]
Pfam domain/function: PF00324 AA_permease [H]
EC number: NA
Molecular weight: Translated: 47577; Mature: 47446
Theoretical pI: Translated: 8.85; Mature: 8.85
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.8 %Cys (Translated Protein) 3.1 %Met (Translated Protein) 4.9 %Cys+Met (Translated Protein) 1.8 %Cys (Mature Protein) 2.9 %Met (Mature Protein) 4.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MGSQELQRKLGFWAVLAIAVGTTVGSGIFVSVGEVAKAAGTPWLTVLAFVIGGLIVIPQM CCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHCCCHHHHHHHHHHHHHHHHHHH CVYAELSTAYPENGADYVYLKNAGSRPLAFLSGWASFWANDAPSLSIMALAIVSNLGFLT HHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCC PIDPLLGKFIAAGLIIAFMLLHLRSVEGGAAFQTLITIAKIIPFTIVIGLGIFWFKAENF CHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCC AAPTTTAIGATGSFMALLAGISATSWSYTGMASICYMTGEIKNPGKTMPRALIGSCLLVL CCCCCHHHCCCHHHHHHHHCCCCCCCCCCCHHHHHHEECCCCCCCCHHHHHHHHHHHHHH VLYTLLALVISGLMPFDKLANSETPISDALTWIPALGSTAGIFVAITAMIVILGSLSSCV HHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH MYQPRLEYAMAKDNLFFKCFGHVHPKYNTPDVSIILQGALGIFFIFVSDLTSLLGYFTLV EECCHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH MCFKNTLTFGSIIWCRKRDDYKPLWRTPAFGLMTTLAIASSLILVASTFVWAPIPGLICA HHHHHHCCHHHEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH VIVIATGLPAYAFWAKRSRQLNALS HHHHHCCCHHHHHHHHHCCCCCCCC >Mature Secondary Structure GSQELQRKLGFWAVLAIAVGTTVGSGIFVSVGEVAKAAGTPWLTVLAFVIGGLIVIPQM CHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHCCCHHHHHHHHHHHHHHHHHHH CVYAELSTAYPENGADYVYLKNAGSRPLAFLSGWASFWANDAPSLSIMALAIVSNLGFLT HHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCC PIDPLLGKFIAAGLIIAFMLLHLRSVEGGAAFQTLITIAKIIPFTIVIGLGIFWFKAENF CHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCC AAPTTTAIGATGSFMALLAGISATSWSYTGMASICYMTGEIKNPGKTMPRALIGSCLLVL CCCCCHHHCCCHHHHHHHHCCCCCCCCCCCHHHHHHEECCCCCCCCHHHHHHHHHHHHHH VLYTLLALVISGLMPFDKLANSETPISDALTWIPALGSTAGIFVAITAMIVILGSLSSCV HHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH MYQPRLEYAMAKDNLFFKCFGHVHPKYNTPDVSIILQGALGIFFIFVSDLTSLLGYFTLV EECCHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH MCFKNTLTFGSIIWCRKRDDYKPLWRTPAFGLMTTLAIASSLILVASTFVWAPIPGLICA HHHHHHCCHHHEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH VIVIATGLPAYAFWAKRSRQLNALS HHHHHCCCHHHHHHHHHCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 11206551; 11258796 [H]