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The map label for this gene is eprH

Identifier: 218696455

GI number: 218696455

Start: 3215047

End: 3216237

Strand: Reverse

Name: eprH

Synonym: EC55989_3140

Alternate gene names: 218696455

Gene position: 3216237-3215047 (Counterclockwise)

Preceding gene: 218696458

Following gene: 218696454

Centisome position: 62.39

GC content: 32.58

Gene sequence:

>1191_bases
GTGGTATTCATGGAAAATAATGATAAATTCTTATCACAAGAATTATTGGAATCTTATGCCATTCGTTTGTTGAGCGGACC
ATTGAATGGATGCGAGTATGAAATACTTAATGGGCGTCTACTTGTTATCATTGGTAATGATGTTTCGTTAGGAAGAAGTG
ATGCTTTTTCTGAGTTACCAGAAAACACAATAGTCGTTCCTTATGGCGAGCTTACAGGTAGTTTTGAGATAATAATTACT
ACCGACCCTGATCTGGTAGTAACATTCAGAGAATTAACAGCACAAGAACCTGAAGATAGAACGTTAACATTGAATCAGCA
AATAGAAGTTTTAGGTCTCAAATTTGCTGTAAAAGAAAAAAATGAAGTTTGGCAGTATTCATTGCCAGGCATTATTGAAA
ATAACATTATTTCTACAAAACAACATTTCTTTAGCAGTAAGCTGTTTAAGTATGTAATGCTTTTTTTTCTTTTTGCTATC
ATTTTCATTGCTTTTTATATTGTTAATGCCAGTAATGATCCGCAGCTGAGACATATCGATAAAATTCTTGTAAACAAAAA
CAGGAATTATGAAATTTTATATGGTAGAGATCATGTTATCTATATTAATACCAATATTTTGGATGAAGCAGTCTGGGTCA
AACAAGCACTGGAAAAAAATCAACCAGGAAAGCCAGTACGGGTGATAAATCCTGATGATGAATCGATACGAATTTTTTCA
TGGCTTGCTGATAATTTCCCTGATTTACAATATTTTAAACTTCAACTATTAGATGCCAGTAATCTAAGATTGACAGTGAG
TAAGCAACGGAACGCTATCACACAGCAACTAATCGATAATCTTATTAAAGGATTACTGCAAACTATGCCATATGCCAGCA
ATATAAGTATTGCGGTATTAGATGATAATGTATTGGAAAGTCAGGCTATTGAAACGTTGTCAGCGATAGGTCTTTCTTAT
GAAAAATATAAAACAGCTAACAATGTGTATTTCAATATCATTGGTACGTTAAGTGACAGTGAATTAAATAAAATTAATAA
CTATGTTGACGAATATTATAAACAATGGGGTAAACAATATGTAAGATTTAATGTGAATTTGAAAAATCAGGACACAAATA
ATAGTTCATTTAGCTACGGAGATAACCGATTCGAGAAGTCTCAAGGTAGCAACTGGACATTTCAGGAATAA

Upstream 100 bases:

>100_bases
TTCTCGAAATTATAATTTTTTTATTCTGTGTCATCATAATTTGGTCATGATATTTCCGTCTTGTTACACTACTCTAAACT
AGAGCTTATGGAATTAGCGG

Downstream 100 bases:

>100_bases
TTGAGGAGGACTTATGGCAGATTGGAATGGTTATATTATGGATATCAGCAATCAATTTGATCAGGGCGTTGATGATCTGA
ACCAGCAAGTTGAAAAAGCG

Product: Putative Type III secretion EprH protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MVFMENNDKFLSQELLESYAIRLLSGPLNGCEYEILNGRLLVIIGNDVSLGRSDAFSELPENTIVVPYGELTGSFEIIIT
TDPDLVVTFRELTAQEPEDRTLTLNQQIEVLGLKFAVKEKNEVWQYSLPGIIENNIISTKQHFFSSKLFKYVMLFFLFAI
IFIAFYIVNASNDPQLRHIDKILVNKNRNYEILYGRDHVIYINTNILDEAVWVKQALEKNQPGKPVRVINPDDESIRIFS
WLADNFPDLQYFKLQLLDASNLRLTVSKQRNAITQQLIDNLIKGLLQTMPYASNISIAVLDDNVLESQAIETLSAIGLSY
EKYKTANNVYFNIIGTLSDSELNKINNYVDEYYKQWGKQYVRFNVNLKNQDTNNSSFSYGDNRFEKSQGSNWTFQE

Sequences:

>Translated_396_residues
MVFMENNDKFLSQELLESYAIRLLSGPLNGCEYEILNGRLLVIIGNDVSLGRSDAFSELPENTIVVPYGELTGSFEIIIT
TDPDLVVTFRELTAQEPEDRTLTLNQQIEVLGLKFAVKEKNEVWQYSLPGIIENNIISTKQHFFSSKLFKYVMLFFLFAI
IFIAFYIVNASNDPQLRHIDKILVNKNRNYEILYGRDHVIYINTNILDEAVWVKQALEKNQPGKPVRVINPDDESIRIFS
WLADNFPDLQYFKLQLLDASNLRLTVSKQRNAITQQLIDNLIKGLLQTMPYASNISIAVLDDNVLESQAIETLSAIGLSY
EKYKTANNVYFNIIGTLSDSELNKINNYVDEYYKQWGKQYVRFNVNLKNQDTNNSSFSYGDNRFEKSQGSNWTFQE
>Mature_396_residues
MVFMENNDKFLSQELLESYAIRLLSGPLNGCEYEILNGRLLVIIGNDVSLGRSDAFSELPENTIVVPYGELTGSFEIIIT
TDPDLVVTFRELTAQEPEDRTLTLNQQIEVLGLKFAVKEKNEVWQYSLPGIIENNIISTKQHFFSSKLFKYVMLFFLFAI
IFIAFYIVNASNDPQLRHIDKILVNKNRNYEILYGRDHVIYINTNILDEAVWVKQALEKNQPGKPVRVINPDDESIRIFS
WLADNFPDLQYFKLQLLDASNLRLTVSKQRNAITQQLIDNLIKGLLQTMPYASNISIAVLDDNVLESQAIETLSAIGLSY
EKYKTANNVYFNIIGTLSDSELNKINNYVDEYYKQWGKQYVRFNVNLKNQDTNNSSFSYGDNRFEKSQGSNWTFQE

Specific function: Required for invasion of epithelial cells [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013387
- InterPro:   IPR019029 [H]

Pfam domain/function: PF09480 PrgH [H]

EC number: NA

Molecular weight: Translated: 45624; Mature: 45624

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVFMENNDKFLSQELLESYAIRLLSGPLNGCEYEILNGRLLVIIGNDVSLGRSDAFSELP
CEEECCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCEEEEEECCCCCCCCCHHHHHCC
ENTIVVPYGELTGSFEIIITTDPDLVVTFRELTAQEPEDRTLTLNQQIEVLGLKFAVKEK
CCCEEEEECCCCCCEEEEEECCCCEEEEEHHHHCCCCCCCEEEECCEEEEEEEEEEEECC
NEVWQYSLPGIIENNIISTKQHFFSSKLFKYVMLFFLFAIIFIAFYIVNASNDPQLRHID
CCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHH
KILVNKNRNYEILYGRDHVIYINTNILDEAVWVKQALEKNQPGKPVRVINPDDESIRIFS
HHHHCCCCCEEEEECCCEEEEEECCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCEEEEE
WLADNFPDLQYFKLQLLDASNLRLTVSKQRNAITQQLIDNLIKGLLQTMPYASNISIAVL
EHHCCCCCCEEEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
DDNVLESQAIETLSAIGLSYEKYKTANNVYFNIIGTLSDSELNKINNYVDEYYKQWGKQY
CCCHHHHHHHHHHHHHCCCHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHCCEE
VRFNVNLKNQDTNNSSFSYGDNRFEKSQGSNWTFQE
EEEEEEECCCCCCCCCCCCCCCHHHHCCCCCCCCCC
>Mature Secondary Structure
MVFMENNDKFLSQELLESYAIRLLSGPLNGCEYEILNGRLLVIIGNDVSLGRSDAFSELP
CEEECCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCEEEEEECCCCCCCCCHHHHHCC
ENTIVVPYGELTGSFEIIITTDPDLVVTFRELTAQEPEDRTLTLNQQIEVLGLKFAVKEK
CCCEEEEECCCCCCEEEEEECCCCEEEEEHHHHCCCCCCCEEEECCEEEEEEEEEEEECC
NEVWQYSLPGIIENNIISTKQHFFSSKLFKYVMLFFLFAIIFIAFYIVNASNDPQLRHID
CCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHH
KILVNKNRNYEILYGRDHVIYINTNILDEAVWVKQALEKNQPGKPVRVINPDDESIRIFS
HHHHCCCCCEEEEECCCEEEEEECCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCEEEEE
WLADNFPDLQYFKLQLLDASNLRLTVSKQRNAITQQLIDNLIKGLLQTMPYASNISIAVL
EHHCCCCCCEEEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
DDNVLESQAIETLSAIGLSYEKYKTANNVYFNIIGTLSDSELNKINNYVDEYYKQWGKQY
CCCHHHHHHHHHHHHHCCCHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHCCEE
VRFNVNLKNQDTNNSSFSYGDNRFEKSQGSNWTFQE
EEEEEEECCCCCCCCCCCCCCCHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7476203; 11677609 [H]