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The map label for this gene is spaR [H]

Identifier: 218696458

GI number: 218696458

Start: 3218508

End: 3219275

Strand: Reverse

Name: spaR [H]

Synonym: EC55989_3146

Alternate gene names: 218696458

Gene position: 3219275-3218508 (Counterclockwise)

Preceding gene: 218696459

Following gene: 218696455

Centisome position: 62.45

GC content: 39.19

Gene sequence:

>768_bases
ATGGAGGAGGCGATACTCTATCAGTTGCATAGTCTGCTGGCTGCTACAGCGCTCGGTTTTTGCCGATTGGCACCAACTTT
CTATTTGTTACCATTTTTCGCCAGTGGGAATATACCAACAGTAGTCCGTCATCCAATAATAATAGTGGTATCATGTGCAT
TATTTCAGCATTACCACTATGAATTATCGACCTTAAATGAAATCGATATCGCTTTGTTTGCTGCCAGAGAAATTATCATA
GGGCTGTTCATTGCTTGCTTATTATCATCCCCGTTTTGGATTTTCCTTGCTATAGGTAGTTTTATCGATAACCAACGTGG
TGCAACGTTAAGTAGTACTTTGGATCCTGCTACTGGTGTCGATACTTCGGAATTAGCAAGATTATTTAACCTATTCTCTG
CAGCGGTTTATCTTACTAACGGTGGATTGAACTTTATTCTGGAAACTCTTTGGCAAAGTTATAATTTATGGCCTTCAGGC
AATTTTAATTTTCCTAAATTAGAGCCTTTATTCTCATATATTAATAACATAATGACTCATACTATCGTTTACGCAAGCCC
CGTGATTGCCGTTATGCTGGGCGGTGAGGCTGTCCTGGGATTGCTGGCACGTTATGCTTCACAACTAAATGCTTTTGCCA
TTTCACTGACTGTCAAAAGTGCGCTGGCATTTTTAATATTAATTATTTATTTTGGCCCAATACTGGCTGAACGAGTAATG
CCGTTATCCTTTTTCCCAGAACAATTGCAACTATACATTGAGAAATAG

Upstream 100 bases:

>100_bases
TGCGTAAGTATTTGCTTTTTTTTAATGAGCGGATGGTATGGTGAAAAATTATATTCGTTTGGTATCGAAATGCTGAATTT
AGCATTCGCGAGAGGATAGG

Downstream 100 bases:

>100_bases
AGTGTTTCATGGCCAATAAAACTGAAAAGCCAACACAAAAGAAACTCCAGGATGCTTCTAAAAAAGGGCAAATTCTAAAA
AGTAGAGACTTAACCATCTC

Product: putative Type III secretion protein EpaR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MEEAILYQLHSLLAATALGFCRLAPTFYLLPFFASGNIPTVVRHPIIIVVSCALFQHYHYELSTLNEIDIALFAAREIII
GLFIACLLSSPFWIFLAIGSFIDNQRGATLSSTLDPATGVDTSELARLFNLFSAAVYLTNGGLNFILETLWQSYNLWPSG
NFNFPKLEPLFSYINNIMTHTIVYASPVIAVMLGGEAVLGLLARYASQLNAFAISLTVKSALAFLILIIYFGPILAERVM
PLSFFPEQLQLYIEK

Sequences:

>Translated_255_residues
MEEAILYQLHSLLAATALGFCRLAPTFYLLPFFASGNIPTVVRHPIIIVVSCALFQHYHYELSTLNEIDIALFAAREIII
GLFIACLLSSPFWIFLAIGSFIDNQRGATLSSTLDPATGVDTSELARLFNLFSAAVYLTNGGLNFILETLWQSYNLWPSG
NFNFPKLEPLFSYINNIMTHTIVYASPVIAVMLGGEAVLGLLARYASQLNAFAISLTVKSALAFLILIIYFGPILAERVM
PLSFFPEQLQLYIEK
>Mature_255_residues
MEEAILYQLHSLLAATALGFCRLAPTFYLLPFFASGNIPTVVRHPIIIVVSCALFQHYHYELSTLNEIDIALFAAREIII
GLFIACLLSSPFWIFLAIGSFIDNQRGATLSSTLDPATGVDTSELARLFNLFSAAVYLTNGGLNFILETLWQSYNLWPSG
NFNFPKLEPLFSYINNIMTHTIVYASPVIAVMLGGEAVLGLLARYASQLNAFAISLTVKSALAFLILIIYFGPILAERVM
PLSFFPEQLQLYIEK

Specific function: Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells [H]

COG id: COG4791

COG function: function code U; Type III secretory pathway, component EscT

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fliR/mopE/spaR family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002010
- InterPro:   IPR006304 [H]

Pfam domain/function: PF01311 Bac_export_1 [H]

EC number: NA

Molecular weight: Translated: 28287; Mature: 28287

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEAILYQLHSLLAATALGFCRLAPTFYLLPFFASGNIPTVVRHPIIIVVSCALFQHYHY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
ELSTLNEIDIALFAAREIIIGLFIACLLSSPFWIFLAIGSFIDNQRGATLSSTLDPATGV
HHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHCCCCCCCCC
DTSELARLFNLFSAAVYLTNGGLNFILETLWQSYNLWPSGNFNFPKLEPLFSYINNIMTH
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHH
TIVYASPVIAVMLGGEAVLGLLARYASQLNAFAISLTVKSALAFLILIIYFGPILAERVM
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PLSFFPEQLQLYIEK
CHHCCHHHHHHHHCC
>Mature Secondary Structure
MEEAILYQLHSLLAATALGFCRLAPTFYLLPFFASGNIPTVVRHPIIIVVSCALFQHYHY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
ELSTLNEIDIALFAAREIIIGLFIACLLSSPFWIFLAIGSFIDNQRGATLSSTLDPATGV
HHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHCCCCCCCCC
DTSELARLFNLFSAAVYLTNGGLNFILETLWQSYNLWPSGNFNFPKLEPLFSYINNIMTH
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHH
TIVYASPVIAVMLGGEAVLGLLARYASQLNAFAISLTVKSALAFLILIIYFGPILAERVM
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PLSFFPEQLQLYIEK
CHHCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8404849; 11677609 [H]