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The map label for this gene is ygcS

Identifier: 218696370

GI number: 218696370

Start: 3112521

End: 3113858

Strand: Reverse

Name: ygcS

Synonym: EC55989_3045

Alternate gene names: 218696370

Gene position: 3113858-3112521 (Counterclockwise)

Preceding gene: 218696371

Following gene: 218696369

Centisome position: 60.41

GC content: 53.21

Gene sequence:

>1338_bases
ATGAACACTTCACCGGTGCGAATGGATGATTTACCGCTTAACCGTTTTCACTGCCGCATTGCTGCGCTCACTTTCGGCGC
ACACCTGACCGACGGTTATGTTCTCGGCGTCATTGGTTACGCCATTATTCAGCTTACGCCCGCCATGCAACTGACGCCGT
TTATGGCGGGAATGATCGGCGGCTCGGCGCTCCTTGGTTTGTTCCTTGGCAGCCTGGTTCTTGGGTGGATCTCCGACCAT
ATTGGTCGGCAAAAAATCTTCACCTTCAGCTTTTTGCTGATTACGCTTGCTTCGTTTTTACAATTTTTTGCCACCACGCC
AGAGCATCTTATTGGACTGCGCATTTTGATTGGCATTGGTCTGGGAGGCGATTATTCAGTAGGTCACACCTTGCTGGCTG
AATTTTCCCCGCGCCGCCATCGCGGTATTTTGCTGGGCGCATTCAGCGTGGTGTGGACCGTAGGCTATGTGCTGGCAAGT
ATTGCCGGACATCACTTTATTTCCGAAAACCCGGAGGCCTGGCGCTGGCTACTGGCATCGGCAGCTCTGCCCGCGTTGTT
GATTACGTTATTACGCTGGGGAACGCCAGAATCACCACGCTGGCTACTGCGCCAGGGGCGTTTTGCAGAAGCTCACGCTA
TCGTGCATCGCTATTTTGGTCCCCATGTTTTACTGGGCGATGAAGTGGTAACGGCGACCCATAAACACATCAAAACCTTG
TTCTCTTCGCGTTACTGGCGGCGCACGGCGTTTAACAGCGTCTTCTTTGTCTGCCTCGTAATCCCATGGTTTGTGATTTA
TACCTGGCTGCCAACTATCGCCCAGACTATTGGTCTGGAAGATGCGCTGACTGCCAGCCTGATGCTTAATGCGTTGTTAA
TTGTGGGCGCGCTGCTGGGATTAGTTCTGACGCACCTGCTGGCACATCGCAAATTTTTGCTGGGAAGTTTTTTGCTGCTG
GCGGCAACGCTGGTAGTAATGGCCTGTTTGCCTTCCGGCAGTTCATTAACGCTGCTGCTTTTTGTTCTCTTCAGCACCAC
CATTTCGGCAGTCAGTAATCTGGTGGGCATTTTGCCTGCGGAAAGTTTTCCTACTGACATTCGCTCGCTGGGCGTCGGTT
TTGCCACCGCCATGAGTCGACTTGGCGCGGCGGTAAGTACTGGCCTGCTGCCGTGGGTGCTGGCGCAGTGGGGAATGCAA
GTCACCTTATTGCTCCTGGCGACAGTGTTGTTGGTTGGTTTTGTTGTGACCTGGCTATGGGCACCAGAAACTAAAGCCCT
CCCGCTGGTGGCGGCGGGAAATGTAGGAGGTGCGAATGAACATTCTGTTAGCGTTTAA

Upstream 100 bases:

>100_bases
AAAATAATGTGTCAGGCAGCGTTCCGCGATGACGGGGCGTTGCCTTTTCGGCTTCTCAGGCGAGAAGCCGTTCTTATTAC
CGGACAATGAAGGGGTAAAG

Downstream 100 bases:

>100_bases
AGCCGAACCGGATGCCGGAATGCTGGCGGAAAAAGAGTGGCAGGCGGCGGCTCAGGGTAAAAGCGGACCGGATATTTCGC
TACTGCGAAGTTTACTCGGT

Product: putative transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MNTSPVRMDDLPLNRFHCRIAALTFGAHLTDGYVLGVIGYAIIQLTPAMQLTPFMAGMIGGSALLGLFLGSLVLGWISDH
IGRQKIFTFSFLLITLASFLQFFATTPEHLIGLRILIGIGLGGDYSVGHTLLAEFSPRRHRGILLGAFSVVWTVGYVLAS
IAGHHFISENPEAWRWLLASAALPALLITLLRWGTPESPRWLLRQGRFAEAHAIVHRYFGPHVLLGDEVVTATHKHIKTL
FSSRYWRRTAFNSVFFVCLVIPWFVIYTWLPTIAQTIGLEDALTASLMLNALLIVGALLGLVLTHLLAHRKFLLGSFLLL
AATLVVMACLPSGSSLTLLLFVLFSTTISAVSNLVGILPAESFPTDIRSLGVGFATAMSRLGAAVSTGLLPWVLAQWGMQ
VTLLLLATVLLVGFVVTWLWAPETKALPLVAAGNVGGANEHSVSV

Sequences:

>Translated_445_residues
MNTSPVRMDDLPLNRFHCRIAALTFGAHLTDGYVLGVIGYAIIQLTPAMQLTPFMAGMIGGSALLGLFLGSLVLGWISDH
IGRQKIFTFSFLLITLASFLQFFATTPEHLIGLRILIGIGLGGDYSVGHTLLAEFSPRRHRGILLGAFSVVWTVGYVLAS
IAGHHFISENPEAWRWLLASAALPALLITLLRWGTPESPRWLLRQGRFAEAHAIVHRYFGPHVLLGDEVVTATHKHIKTL
FSSRYWRRTAFNSVFFVCLVIPWFVIYTWLPTIAQTIGLEDALTASLMLNALLIVGALLGLVLTHLLAHRKFLLGSFLLL
AATLVVMACLPSGSSLTLLLFVLFSTTISAVSNLVGILPAESFPTDIRSLGVGFATAMSRLGAAVSTGLLPWVLAQWGMQ
VTLLLLATVLLVGFVVTWLWAPETKALPLVAAGNVGGANEHSVSV
>Mature_445_residues
MNTSPVRMDDLPLNRFHCRIAALTFGAHLTDGYVLGVIGYAIIQLTPAMQLTPFMAGMIGGSALLGLFLGSLVLGWISDH
IGRQKIFTFSFLLITLASFLQFFATTPEHLIGLRILIGIGLGGDYSVGHTLLAEFSPRRHRGILLGAFSVVWTVGYVLAS
IAGHHFISENPEAWRWLLASAALPALLITLLRWGTPESPRWLLRQGRFAEAHAIVHRYFGPHVLLGDEVVTATHKHIKTL
FSSRYWRRTAFNSVFFVCLVIPWFVIYTWLPTIAQTIGLEDALTASLMLNALLIVGALLGLVLTHLLAHRKFLLGSFLLL
AATLVVMACLPSGSSLTLLLFVLFSTTISAVSNLVGILPAESFPTDIRSLGVGFATAMSRLGAAVSTGLLPWVLAQWGMQ
VTLLLLATVLLVGFVVTWLWAPETKALPLVAAGNVGGANEHSVSV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family

Homologues:

Organism=Homo sapiens, GI4507005, Length=383, Percent_Identity=26.3707571801567, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI302148518, Length=365, Percent_Identity=25.2054794520548, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI4506999, Length=425, Percent_Identity=25.4117647058824, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI166197673, Length=365, Percent_Identity=28.2191780821918, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI24497490, Length=334, Percent_Identity=26.0479041916168, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI24308167, Length=446, Percent_Identity=23.7668161434978, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI23510410, Length=374, Percent_Identity=24.0641711229947, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI21553331, Length=312, Percent_Identity=24.0384615384615, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI7662270, Length=211, Percent_Identity=27.4881516587678, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI296080721, Length=345, Percent_Identity=27.2463768115942, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI296080719, Length=347, Percent_Identity=27.0893371757925, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI24497499, Length=347, Percent_Identity=27.0893371757925, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI296080734, Length=345, Percent_Identity=27.2463768115942, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI213021148, Length=419, Percent_Identity=25.5369928400955, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI24497476, Length=380, Percent_Identity=25.7894736842105, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI20070188, Length=380, Percent_Identity=25.7894736842105, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI90669191, Length=347, Percent_Identity=27.3775216138329, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI24497497, Length=347, Percent_Identity=27.3775216138329, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI8923870, Length=382, Percent_Identity=24.6073298429319, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI11415038, Length=375, Percent_Identity=24.8, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI203098995, Length=197, Percent_Identity=27.4111675126904, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI166064021, Length=376, Percent_Identity=24.7340425531915, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI87082159, Length=445, Percent_Identity=100, Blast_Score=873, Evalue=0.0,
Organism=Escherichia coli, GI1786229, Length=431, Percent_Identity=34.338747099768, Blast_Score=257, Evalue=1e-69,
Organism=Escherichia coli, GI1788074, Length=418, Percent_Identity=26.0765550239234, Blast_Score=101, Evalue=8e-23,
Organism=Escherichia coli, GI1788068, Length=451, Percent_Identity=24.6119733924612, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1789207, Length=445, Percent_Identity=26.0674157303371, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1790463, Length=427, Percent_Identity=23.4192037470726, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789312, Length=436, Percent_Identity=24.3119266055046, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87082404, Length=405, Percent_Identity=22.7160493827161, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI87082231, Length=416, Percent_Identity=24.0384615384615, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17556354, Length=408, Percent_Identity=27.9411764705882, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17565976, Length=154, Percent_Identity=29.8701298701299, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17565978, Length=327, Percent_Identity=25.0764525993884, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71988651, Length=156, Percent_Identity=35.2564102564103, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17560496, Length=395, Percent_Identity=23.7974683544304, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193209824, Length=388, Percent_Identity=25.7731958762887, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17564080, Length=407, Percent_Identity=25.0614250614251, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17554160, Length=403, Percent_Identity=25.0620347394541, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI25145172, Length=398, Percent_Identity=23.6180904522613, Blast_Score=65, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6320595, Length=183, Percent_Identity=32.2404371584699, Blast_Score=76, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6323653, Length=365, Percent_Identity=21.6438356164384, Blast_Score=63, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24649618, Length=339, Percent_Identity=26.2536873156342, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI19922616, Length=394, Percent_Identity=25.3807106598985, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24649622, Length=387, Percent_Identity=24.031007751938, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24668456, Length=408, Percent_Identity=25.2450980392157, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24668440, Length=406, Percent_Identity=24.1379310344828, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24640198, Length=436, Percent_Identity=23.1651376146789, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24640196, Length=436, Percent_Identity=23.1651376146789, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24640200, Length=436, Percent_Identity=23.1651376146789, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24649616, Length=356, Percent_Identity=25.8426966292135, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI161078338, Length=399, Percent_Identity=26.3157894736842, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19922874, Length=406, Percent_Identity=25.3694581280788, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24647365, Length=404, Percent_Identity=25.990099009901, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI161077756, Length=455, Percent_Identity=23.7362637362637, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YGCS_ECOLI (Q46909)

Other databases:

- EMBL:   U29579
- EMBL:   U00096
- EMBL:   AP009048
- PIR:   G65058
- RefSeq:   AP_003338.1
- RefSeq:   NP_417251.2
- ProteinModelPortal:   Q46909
- STRING:   Q46909
- EnsemblBacteria:   EBESCT00000003081
- EnsemblBacteria:   EBESCT00000014238
- GeneID:   947238
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW5845
- KEGG:   eco:b2771
- EchoBASE:   EB2927
- EcoGene:   EG13126
- eggNOG:   COG0477
- GeneTree:   EBGT00050000008817
- HOGENOM:   HBG516586
- OMA:   ATATHKH
- ProtClustDB:   CLSK880921
- BioCyc:   EcoCyc:B2771-MONOMER
- Genevestigator:   Q46909
- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828
- InterPro:   IPR005829

Pfam domain/function: PF00083 Sugar_tr; SSF103473 MFS_gen_substrate_transporter

EC number: NA

Molecular weight: Translated: 48235; Mature: 48235

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: PS50850 MFS; PS00216 SUGAR_TRANSPORT_1; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x17f7f460)-; HASH(0x1ae13a90)-; HASH(0x1bb02bd8)-; HASH(0x1bfd1774)-; HASH(0x1b8f8d24)-; HASH(0x1b90b274)-; HASH(0x1baf9478)-; HASH(0x1b98eb84)-; HASH(0x1c081d8c)-; HASH(0x1b67cfb4)-; HASH(0x1557a47c)-; HASH(0x1bd13e70)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTSPVRMDDLPLNRFHCRIAALTFGAHLTDGYVLGVIGYAIIQLTPAMQLTPFMAGMIG
CCCCCCCCCCCCCHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHH
GSALLGLFLGSLVLGWISDHIGRQKIFTFSFLLITLASFLQFFATTPEHLIGLRILIGIG
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHEEC
LGGDYSVGHTLLAEFSPRRHRGILLGAFSVVWTVGYVLASIAGHHFISENPEAWRWLLAS
CCCCCHHHHHHHHHCCCCHHCCHHHHHHHHHHHHHHHHHHHHHCHHCCCCHHHHHHHHHH
AALPALLITLLRWGTPESPRWLLRQGRFAEAHAIVHRYFGPHVLLGDEVVTATHKHIKTL
HHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHH
FSSRYWRRTAFNSVFFVCLVIPWFVIYTWLPTIAQTIGLEDALTASLMLNALLIVGALLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LVLTHLLAHRKFLLGSFLLLAATLVVMACLPSGSSLTLLLFVLFSTTISAVSNLVGILPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
ESFPTDIRSLGVGFATAMSRLGAAVSTGLLPWVLAQWGMQVTLLLLATVLLVGFVVTWLW
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
APETKALPLVAAGNVGGANEHSVSV
CCCCCCCEEEEECCCCCCCCCCCCH
>Mature Secondary Structure
MNTSPVRMDDLPLNRFHCRIAALTFGAHLTDGYVLGVIGYAIIQLTPAMQLTPFMAGMIG
CCCCCCCCCCCCCHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHH
GSALLGLFLGSLVLGWISDHIGRQKIFTFSFLLITLASFLQFFATTPEHLIGLRILIGIG
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHEEC
LGGDYSVGHTLLAEFSPRRHRGILLGAFSVVWTVGYVLASIAGHHFISENPEAWRWLLAS
CCCCCHHHHHHHHHCCCCHHCCHHHHHHHHHHHHHHHHHHHHHCHHCCCCHHHHHHHHHH
AALPALLITLLRWGTPESPRWLLRQGRFAEAHAIVHRYFGPHVLLGDEVVTATHKHIKTL
HHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHH
FSSRYWRRTAFNSVFFVCLVIPWFVIYTWLPTIAQTIGLEDALTASLMLNALLIVGALLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LVLTHLLAHRKFLLGSFLLLAATLVVMACLPSGSSLTLLLFVLFSTTISAVSNLVGILPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
ESFPTDIRSLGVGFATAMSRLGAAVSTGLLPWVLAQWGMQVTLLLLATVLLVGFVVTWLW
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
APETKALPLVAAGNVGGANEHSVSV
CCCCCCCEEEEECCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503