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The map label for this gene is cscR

Identifier: 218696007

GI number: 218696007

Start: 2710121

End: 2711302

Strand: Reverse

Name: cscR

Synonym: EC55989_2657

Alternate gene names: 218696007

Gene position: 2711302-2710121 (Counterclockwise)

Preceding gene: 218696009

Following gene: 218696005

Centisome position: 52.6

GC content: 51.1

Gene sequence:

>1182_bases
TTGGCATGTTTTACTTACTTGCCTATATGGTTACTCGTTGGCGAGAACAGAGGCGGAATTGGGGACAATTGTCCGGGAAT
TATTGTTATTTTTTATTGTATTGCTGTGTCAGGTGATAGGGCGTTAGATCTCGCCAGTGACGTCTGTTTCTGCTACAGTG
CCCGTTTTACGGCAAACGGCTTGGGTATGGCTTCATTAAAGGATGTCGCACGCCTGGCGGGAGTGTCGATGATGACAGTC
TCCCGGGTGATGCATAATGCAGAATCTGTGCGTCCTGCAACGCGTGACCGCGTATTGCAGGCAATCCAGACCCTGAATTA
TGTTCCTGATCTTTCCGCCCGTAAGATGCGCGCTCAAGGACGTAAGCCGTCGACTCTCGCCGTGCTGGCGCAGGACACGG
CTACCACTCCTTTCTCTGTTGATATTCTGCTTGCCATTGAGCAAACCGCCAGCGAGTTCGGCTGGAATAGTTTTTTAATC
AATATTTTTTCTGAAGATGACGCTGCCCGCGCGGCACGTCAGCTGCTTGCCCACCGTCCGGATGGCATTATCTATACTAC
AATGGGGCTGCGACATATCACGCTGCCTGAGTCTCTGTATGGTGAAAATATTGTATTGGCGAACTGTGTGGCGGATGACC
CAGCGTTACCCAGTTATATCCCTGATGATTACACTGCACAATATGAATCAACACAGCATTTGCTCGCGGCGGGCTATCGT
CAACCGTTATGCTTCTGGCTACCGGAAAGTGCGTTGGCAACAGGGTATCGTCGGCAGGGATTTGAGCAGGCCTGGCGTGA
TGCTGGACGAGATCTGGCTGAGGTGAAACAATTTCACATGGCAACAGGTGATGATCACTACACCGATCTCGCAAGTTTAC
TCAATGCCCACTTCAAACCGGGCAAACCAGATTTTGATGTTCTGATATGTGGTAACGATCGCGCAGCCTTTGTGGCTTAT
CAGGTTCTTCTGGCGAAGGGGGTACGAATCCCGCAGGATGTCGCCGTAATGGGCTTTGATAATCTGGTTGGCGTCGGGCA
TCTGTTTTTACCGCCGCTGACCACAATTCAGCTTCCACATGACATTATCGGGCGGGAAGCTGCATTGCATATTATTGAAG
GTCGTGAAGGGGGAAGAGTGACGCGGATCCCTTGCCCGCTGTTGATCCGTTGTTCCACCTGA

Upstream 100 bases:

>100_bases
GAACCGATAGCAATCGCAATAATTTCCGGGCTGATGTCGGGATACAGCGGCAGCACAATGATCCATATTTATATTTTCTT
CTCCAGGTTGGCGATGCCAG

Downstream 100 bases:

>100_bases
TATTATGTTAACCCAGTAGCCAGAGTGCTCCATGTTGCAGCACAGCCACTCCGTGGGAGGCATAAAGCGACAGTTCCCGT
TCTTCTGGCTGCGGATAGAT

Product: Sucrose operon repressor (Csc operon regulatory protein)

Products: NA

Alternate protein names: Csc operon regulatory protein [H]

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MACFTYLPIWLLVGENRGGIGDNCPGIIVIFYCIAVSGDRALDLASDVCFCYSARFTANGLGMASLKDVARLAGVSMMTV
SRVMHNAESVRPATRDRVLQAIQTLNYVPDLSARKMRAQGRKPSTLAVLAQDTATTPFSVDILLAIEQTASEFGWNSFLI
NIFSEDDAARAARQLLAHRPDGIIYTTMGLRHITLPESLYGENIVLANCVADDPALPSYIPDDYTAQYESTQHLLAAGYR
QPLCFWLPESALATGYRRQGFEQAWRDAGRDLAEVKQFHMATGDDHYTDLASLLNAHFKPGKPDFDVLICGNDRAAFVAY
QVLLAKGVRIPQDVAVMGFDNLVGVGHLFLPPLTTIQLPHDIIGREAALHIIEGREGGRVTRIPCPLLIRCST

Sequences:

>Translated_393_residues
MACFTYLPIWLLVGENRGGIGDNCPGIIVIFYCIAVSGDRALDLASDVCFCYSARFTANGLGMASLKDVARLAGVSMMTV
SRVMHNAESVRPATRDRVLQAIQTLNYVPDLSARKMRAQGRKPSTLAVLAQDTATTPFSVDILLAIEQTASEFGWNSFLI
NIFSEDDAARAARQLLAHRPDGIIYTTMGLRHITLPESLYGENIVLANCVADDPALPSYIPDDYTAQYESTQHLLAAGYR
QPLCFWLPESALATGYRRQGFEQAWRDAGRDLAEVKQFHMATGDDHYTDLASLLNAHFKPGKPDFDVLICGNDRAAFVAY
QVLLAKGVRIPQDVAVMGFDNLVGVGHLFLPPLTTIQLPHDIIGREAALHIIEGREGGRVTRIPCPLLIRCST
>Mature_392_residues
ACFTYLPIWLLVGENRGGIGDNCPGIIVIFYCIAVSGDRALDLASDVCFCYSARFTANGLGMASLKDVARLAGVSMMTVS
RVMHNAESVRPATRDRVLQAIQTLNYVPDLSARKMRAQGRKPSTLAVLAQDTATTPFSVDILLAIEQTASEFGWNSFLIN
IFSEDDAARAARQLLAHRPDGIIYTTMGLRHITLPESLYGENIVLANCVADDPALPSYIPDDYTAQYESTQHLLAAGYRQ
PLCFWLPESALATGYRRQGFEQAWRDAGRDLAEVKQFHMATGDDHYTDLASLLNAHFKPGKPDFDVLICGNDRAAFVAYQ
VLLAKGVRIPQDVAVMGFDNLVGVGHLFLPPLTTIQLPHDIIGREAALHIIEGREGGRVTRIPCPLLIRCST

Specific function: Repressor for the csc operon. Binds D-fructose as an inducer [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=338, Percent_Identity=29.585798816568, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1790194, Length=334, Percent_Identity=28.4431137724551, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1787948, Length=321, Percent_Identity=27.1028037383178, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1789202, Length=309, Percent_Identity=28.4789644012945, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1786540, Length=346, Percent_Identity=26.3005780346821, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1789068, Length=316, Percent_Identity=27.5316455696203, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787580, Length=316, Percent_Identity=23.4177215189873, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790689, Length=329, Percent_Identity=27.355623100304, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI48994940, Length=323, Percent_Identity=25.6965944272446, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 43088; Mature: 42957

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MACFTYLPIWLLVGENRGGIGDNCPGIIVIFYCIAVSGDRALDLASDVCFCYSARFTANG
CCHHHEEEEEEEEECCCCCCCCCCCHHHHHEEHHHCCCCCHHHHHHHHHHHHCCCCCCCC
LGMASLKDVARLAGVSMMTVSRVMHNAESVRPATRDRVLQAIQTLNYVPDLSARKMRAQG
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHCC
RKPSTLAVLAQDTATTPFSVDILLAIEQTASEFGWNSFLINIFSEDDAARAARQLLAHRP
CCCCEEEEEECCCCCCCEEEEEEEEEEHHHHHCCCCEEEEEEECCCHHHHHHHHHHHCCC
DGIIYTTMGLRHITLPESLYGENIVLANCVADDPALPSYIPDDYTAQYESTQHLLAAGYR
CCEEEEECCEEEEECCHHHCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCC
QPLCFWLPESALATGYRRQGFEQAWRDAGRDLAEVKQFHMATGDDHYTDLASLLNAHFKP
CCEEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCC
GKPDFDVLICGNDRAAFVAYQVLLAKGVRIPQDVAVMGFDNLVGVGHLFLPPLTTIQLPH
CCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCEEEECCHHHHHCCHHHCCCCCEEECCH
DIIGREAALHIIEGREGGRVTRIPCPLLIRCST
HHHCCCCEEEEEECCCCCEEEEECCCEEEEECC
>Mature Secondary Structure 
ACFTYLPIWLLVGENRGGIGDNCPGIIVIFYCIAVSGDRALDLASDVCFCYSARFTANG
CHHHEEEEEEEEECCCCCCCCCCCHHHHHEEHHHCCCCCHHHHHHHHHHHHCCCCCCCC
LGMASLKDVARLAGVSMMTVSRVMHNAESVRPATRDRVLQAIQTLNYVPDLSARKMRAQG
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHCC
RKPSTLAVLAQDTATTPFSVDILLAIEQTASEFGWNSFLINIFSEDDAARAARQLLAHRP
CCCCEEEEEECCCCCCCEEEEEEEEEEHHHHHCCCCEEEEEEECCCHHHHHHHHHHHCCC
DGIIYTTMGLRHITLPESLYGENIVLANCVADDPALPSYIPDDYTAQYESTQHLLAAGYR
CCEEEEECCEEEEECCHHHCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCC
QPLCFWLPESALATGYRRQGFEQAWRDAGRDLAEVKQFHMATGDDHYTDLASLLNAHFKP
CCEEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCC
GKPDFDVLICGNDRAAFVAYQVLLAKGVRIPQDVAVMGFDNLVGVGHLFLPPLTTIQLPH
CCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCEEEECCHHHHHCCHHHCCCCCEEECCH
DIIGREAALHIIEGREGGRVTRIPCPLLIRCST
HHHCCCCEEEEEECCCCCEEEEECCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA