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The map label for this gene is 218695662

Identifier: 218695662

GI number: 218695662

Start: 2340327

End: 2341367

Strand: Reverse

Name: 218695662

Synonym: EC55989_2295

Alternate gene names: NA

Gene position: 2341367-2340327 (Counterclockwise)

Preceding gene: 218695663

Following gene: 218695661

Centisome position: 45.42

GC content: 33.43

Gene sequence:

>1041_bases
ATGAATAAAATATATATTGTGGCTGAAATTGGATGTAATCATAATGGTGATTTTAATCTTGCAAAAAAAATGGTTGAAGA
AGCCAAAAAAGCTGGTGTTGATGCAGTCAAATTTCAGACTTTTAAAGCTGATCAATTAATTTCGAAATACGCACCTAAGG
CAGAGTATCAGATAAAAGTAACTGGTAATCAGGAATCCCAATTAGAAATGACAAGGAAGCTTGAGCTGCCTTATGAAGAG
TTTATAAAACTTGAAGAATATGCAAAAGAGTTAGGACTTGATGTCTTTTCAACACCATTTGATTTTGAATCTATCGATTT
TCTTGCTTCAAGAAATCAAAAAATGTGGAAAATACCTTCAGGTGAATTGCTTAATCTCCCGTATCTTGAAAAAATAAGCA
GATTGCCGATTGAGGGAAAAGAGATTGTATTGTCAACAGGAATGGCCACAATTGAAGAAATCAAAGCAAGTGTAAATGTT
CTTACTAAAAATGGAATGGTTCCTGAAAAGATCACAATATTACATTGTAACACTGAATATCCTACACCATATGAAGATGT
AAATTTAAACTCAATTATTGGTCTAAAGAATGAATTTAAAGGATATAACGTTGGCTTTTCTGACCATTCACCAGGTTATT
ATGCAGCTATTGCATCAGTTCCGTATGGAATTACATTCATCGAAAAACATTTTACTCTAAATAAAGATTTTGAAGGGCCT
GATCATAAGGCATCAGTTACACCAGATGAGCTACGATTATTGTGTGAGGGGATTCGGGCTGTTGAAAAATGTTTAGGAAG
CTATGCGAAAATAGTAACAAAATCTGAACAAAAAAATAAGATAGTAGCAAGAAAGTCCATAGTGGCAAAATGCAACATTA
AAAAAGGTGAAATATATACGATTGATAATATCACCACAAAGCGGCCAGGAAACGGAATTAGTCCTATGTATTGGTATGAT
ATCTTAGGCAAGAAGGCGGAAAAAAATTTCGATGAGGATCAATTAATAAGTCATTCTGGATTCGATGAACAGGAGATCTA
A

Upstream 100 bases:

>100_bases
TCGACAATTGTTGGATCTGGATCAGTAGTAATACGAAACATCCCTAATAATGTTGTTGTTGCAGGAACACCAACAAGATT
AATAAGAGAAAGGTAAGCAA

Downstream 100 bases:

>100_bases
TTTAAATGACTAATAGGATAGCGATAATTCCGGCTAGAGCGGGATCAAAAGGGTTACCAAATAAAAATGTTTTAATGTTA
ATAGATAAACCTCTTATAGC

Product: NnaB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MNKIYIVAEIGCNHNGDFNLAKKMVEEAKKAGVDAVKFQTFKADQLISKYAPKAEYQIKVTGNQESQLEMTRKLELPYEE
FIKLEEYAKELGLDVFSTPFDFESIDFLASRNQKMWKIPSGELLNLPYLEKISRLPIEGKEIVLSTGMATIEEIKASVNV
LTKNGMVPEKITILHCNTEYPTPYEDVNLNSIIGLKNEFKGYNVGFSDHSPGYYAAIASVPYGITFIEKHFTLNKDFEGP
DHKASVTPDELRLLCEGIRAVEKCLGSYAKIVTKSEQKNKIVARKSIVAKCNIKKGEIYTIDNITTKRPGNGISPMYWYD
ILGKKAEKNFDEDQLISHSGFDEQEI

Sequences:

>Translated_346_residues
MNKIYIVAEIGCNHNGDFNLAKKMVEEAKKAGVDAVKFQTFKADQLISKYAPKAEYQIKVTGNQESQLEMTRKLELPYEE
FIKLEEYAKELGLDVFSTPFDFESIDFLASRNQKMWKIPSGELLNLPYLEKISRLPIEGKEIVLSTGMATIEEIKASVNV
LTKNGMVPEKITILHCNTEYPTPYEDVNLNSIIGLKNEFKGYNVGFSDHSPGYYAAIASVPYGITFIEKHFTLNKDFEGP
DHKASVTPDELRLLCEGIRAVEKCLGSYAKIVTKSEQKNKIVARKSIVAKCNIKKGEIYTIDNITTKRPGNGISPMYWYD
ILGKKAEKNFDEDQLISHSGFDEQEI
>Mature_346_residues
MNKIYIVAEIGCNHNGDFNLAKKMVEEAKKAGVDAVKFQTFKADQLISKYAPKAEYQIKVTGNQESQLEMTRKLELPYEE
FIKLEEYAKELGLDVFSTPFDFESIDFLASRNQKMWKIPSGELLNLPYLEKISRLPIEGKEIVLSTGMATIEEIKASVNV
LTKNGMVPEKITILHCNTEYPTPYEDVNLNSIIGLKNEFKGYNVGFSDHSPGYYAAIASVPYGITFIEKHFTLNKDFEGP
DHKASVTPDELRLLCEGIRAVEKCLGSYAKIVTKSEQKNKIVARKSIVAKCNIKKGEIYTIDNITTKRPGNGISPMYWYD
ILGKKAEKNFDEDQLISHSGFDEQEI

Specific function: Unknown

COG id: COG2089

COG function: function code M; Sialic acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis spsE [H]

Homologues:

Organism=Homo sapiens, GI12056473, Length=334, Percent_Identity=33.2335329341317, Blast_Score=182, Evalue=6e-46,
Organism=Drosophila melanogaster, GI21357081, Length=360, Percent_Identity=31.1111111111111, Blast_Score=160, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006190
- InterPro:   IPR013785
- InterPro:   IPR013132
- InterPro:   IPR013974 [H]

Pfam domain/function: PF03102 NeuB; PF08666 SAF [H]

EC number: NA

Molecular weight: Translated: 39109; Mature: 39109

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: PS50844 AFP_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKIYIVAEIGCNHNGDFNLAKKMVEEAKKAGVDAVKFQTFKADQLISKYAPKAEYQIKV
CCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHCCCCCEEEEEE
TGNQESQLEMTRKLELPYEEFIKLEEYAKELGLDVFSTPFDFESIDFLASRNQKMWKIPS
ECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCEEEECCC
GELLNLPYLEKISRLPIEGKEIVLSTGMATIEEIKASVNVLTKNGMVPEKITILHCNTEY
CCEECCHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHEEECCCCCCCEEEEEEECCCC
PTPYEDVNLNSIIGLKNEFKGYNVGFSDHSPGYYAAIASVPYGITFIEKHFTLNKDFEGP
CCCCCCCCCHHEECCHHHCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEEEEECCCCCCC
DHKASVTPDELRLLCEGIRAVEKCLGSYAKIVTKSEQKNKIVARKSIVAKCNIKKGEIYT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEEECCCCCCEEE
IDNITTKRPGNGISPMYWYDILGKKAEKNFDEDQLISHSGFDEQEI
ECCCEECCCCCCCCHHHHHHHHCCHHHCCCCHHHHHHCCCCCCCCC
>Mature Secondary Structure
MNKIYIVAEIGCNHNGDFNLAKKMVEEAKKAGVDAVKFQTFKADQLISKYAPKAEYQIKV
CCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHCCCCCEEEEEE
TGNQESQLEMTRKLELPYEEFIKLEEYAKELGLDVFSTPFDFESIDFLASRNQKMWKIPS
ECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCEEEECCC
GELLNLPYLEKISRLPIEGKEIVLSTGMATIEEIKASVNVLTKNGMVPEKITILHCNTEY
CCEECCHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHEEECCCCCCCEEEEEEECCCC
PTPYEDVNLNSIIGLKNEFKGYNVGFSDHSPGYYAAIASVPYGITFIEKHFTLNKDFEGP
CCCCCCCCCHHEECCHHHCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEEEEECCCCCCC
DHKASVTPDELRLLCEGIRAVEKCLGSYAKIVTKSEQKNKIVARKSIVAKCNIKKGEIYT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEEECCCCCCEEE
IDNITTKRPGNGISPMYWYDILGKKAEKNFDEDQLISHSGFDEQEI
ECCCEECCCCCCCCHHHHHHHHCCHHHCCCCHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]