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The map label for this gene is ddpX

Identifier: 218695025

GI number: 218695025

Start: 1674857

End: 1675438

Strand: Reverse

Name: ddpX

Synonym: EC55989_1620

Alternate gene names: 218695025

Gene position: 1675438-1674857 (Counterclockwise)

Preceding gene: 218695026

Following gene: 218695024

Centisome position: 32.5

GC content: 52.92

Gene sequence:

>582_bases
ATGTCGGATACCACCGAACTGGTTGATTTAGCCGTAATCTTCCCTGATCTGGAGATCGAATTGAAATACGCCTGCGCTGA
TAACATCACAGGTAAAGCTATTTATCAGCAAGCGCGTTGTCTGTTACACAAGGATGCGATTACCGCGCTGGCGAAAAGTA
TCAGCATCGCCCAGCTGTCAGGCTTACAACTGGTGATTTACGATGCGTATCGCCCACAACAAGCACAGGCGATGTTGTGG
CAAGCCTGCCCAGACCCGCAATATGTTGTTGATGTGACGGTCGGTTCTAATCACAGCCGTGGCACGGCGATCGACCTGAC
GCTTCGTGATGAGCACGGGAACATCCTCGATATGGGCGCAGGGTTCGATGAAATGCACGAGCGCTCCCATGCCTATCACC
CTTCCGTCCCGCCCGCCGCTCAGCGCAATCGGCTGTTGCTGAATGCGATAATGACTGGTGGCGGTTTTGTCGGTATCTCC
AGCGAATGGTGGCACTTCGAATTACCCCAGGCAGCGAGTTACCCTCTGCTCGCTGATCAATTCTCTTGTTTTATATCCCC
TGGCACACAGCACGTCAGTTAA

Upstream 100 bases:

>100_bases
AATATAACTTTAAGCCAGCATTCTGGCGCTTCTCCCGGCATGGCATGAGATCTGCATAAGCGGAAAGCGCAGCAATTTTT
GTCTTATACAGGAACCGTTT

Downstream 100 bases:

>100_bases
TCAGGAAACTGTCATGAAGAGATCGATATCGTTTCGTCCCACATTGCTCGCGCTCGTCCTTGCCACAAATTTCCCGGTTG
CGCACGCCGCCGTACCAAAA

Product: D-alanyl-D-alanine dipeptidase

Products: NA

Alternate protein names: D-Ala-D-Ala dipeptidase

Number of amino acids: Translated: 193; Mature: 192

Protein sequence:

>193_residues
MSDTTELVDLAVIFPDLEIELKYACADNITGKAIYQQARCLLHKDAITALAKSISIAQLSGLQLVIYDAYRPQQAQAMLW
QACPDPQYVVDVTVGSNHSRGTAIDLTLRDEHGNILDMGAGFDEMHERSHAYHPSVPPAAQRNRLLLNAIMTGGGFVGIS
SEWWHFELPQAASYPLLADQFSCFISPGTQHVS

Sequences:

>Translated_193_residues
MSDTTELVDLAVIFPDLEIELKYACADNITGKAIYQQARCLLHKDAITALAKSISIAQLSGLQLVIYDAYRPQQAQAMLW
QACPDPQYVVDVTVGSNHSRGTAIDLTLRDEHGNILDMGAGFDEMHERSHAYHPSVPPAAQRNRLLLNAIMTGGGFVGIS
SEWWHFELPQAASYPLLADQFSCFISPGTQHVS
>Mature_192_residues
SDTTELVDLAVIFPDLEIELKYACADNITGKAIYQQARCLLHKDAITALAKSISIAQLSGLQLVIYDAYRPQQAQAMLWQ
ACPDPQYVVDVTVGSNHSRGTAIDLTLRDEHGNILDMGAGFDEMHERSHAYHPSVPPAAQRNRLLLNAIMTGGGFVGISS
EWWHFELPQAASYPLLADQFSCFISPGTQHVS

Specific function: Hydrolyzes D-Ala-D-Ala. May have a role in cell-wall turnover

COG id: COG2173

COG function: function code M; D-alanyl-D-alanine dipeptidase

Gene ontology:

Cell location: Secreted (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M15D family

Homologues:

Organism=Escherichia coli, GI1787763, Length=193, Percent_Identity=100, Blast_Score=403, Evalue=1e-114,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DDPX_ECOLI (P77790)

Other databases:

- EMBL:   U00096
- EMBL:   AP009048
- PIR:   C64902
- RefSeq:   AP_002111.1
- RefSeq:   NP_416005.1
- ProteinModelPortal:   P77790
- SMR:   P77790
- DIP:   DIP-9418N
- STRING:   P77790
- MEROPS:   M15.011
- EnsemblBacteria:   EBESCT00000001205
- EnsemblBacteria:   EBESCT00000017929
- GeneID:   945532
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW1483
- KEGG:   eco:b1488
- EchoBASE:   EB3552
- EcoGene:   EG13791
- eggNOG:   COG2173
- GeneTree:   EBGT00050000010276
- HOGENOM:   HBG565067
- OMA:   EWWHFTL
- ProtClustDB:   PRK10178
- BioCyc:   EcoCyc:G6782-MONOMER
- Genevestigator:   P77790
- GO:   GO:0006508
- InterPro:   IPR009045
- InterPro:   IPR000755
- Gene3D:   G3DSA:3.30.1380.10
- PIRSF:   PIRSF026671

Pfam domain/function: PF01427 Peptidase_M15; SSF55166 Hedgehog_sig_N

EC number: =3.4.13.22

Molecular weight: Translated: 21213; Mature: 21082

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDTTELVDLAVIFPDLEIELKYACADNITGKAIYQQARCLLHKDAITALAKSISIAQLS
CCCHHHEEEEEEEECCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEC
GLQLVIYDAYRPQQAQAMLWQACPDPQYVVDVTVGSNHSRGTAIDLTLRDEHGNILDMGA
CCEEEEEECCCCCHHHHHHHHCCCCCCEEEEEEECCCCCCCEEEEEEEECCCCCEEECCC
GFDEMHERSHAYHPSVPPAAQRNRLLLNAIMTGGGFVGISSEWWHFELPQAASYPLLADQ
CHHHHHHHCCCCCCCCCCCHHCCEEEEEEEECCCEEEEECCCCEEEECCCCCCCCEECCC
FSCFISPGTQHVS
EEEEECCCCCCCC
>Mature Secondary Structure 
SDTTELVDLAVIFPDLEIELKYACADNITGKAIYQQARCLLHKDAITALAKSISIAQLS
CCHHHEEEEEEEECCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEC
GLQLVIYDAYRPQQAQAMLWQACPDPQYVVDVTVGSNHSRGTAIDLTLRDEHGNILDMGA
CCEEEEEECCCCCHHHHHHHHCCCCCCEEEEEEECCCCCCCEEEEEEEECCCCCEEECCC
GFDEMHERSHAYHPSVPPAAQRNRLLLNAIMTGGGFVGISSEWWHFELPQAASYPLLADQ
CHHHHHHHCCCCCCCCCCCHHCCEEEEEEEECCCEEEEECCCCEEEECCCCCCCCEECCC
FSCFISPGTQHVS
EEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 9751644