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The map label for this gene is ddpA

Identifier: 218695024

GI number: 218695024

Start: 1673293

End: 1674843

Strand: Reverse

Name: ddpA

Synonym: EC55989_1619

Alternate gene names: 218695024

Gene position: 1674843-1673293 (Counterclockwise)

Preceding gene: 218695025

Following gene: 218695023

Centisome position: 32.49

GC content: 50.42

Gene sequence:

>1551_bases
ATGAAGAGATCGATATCGTTTCGTCCCACATTGCTCGCGCTCGTCCTTGCCACAAATTTCCCGGTTGCGCACGCCGCCGT
ACCAAAAGATATGCTGGTGATTGGTAAGGCCGCCGATCCACAAACCCTCGACCCGGCGGTAACAATAGATAATAACGACT
GGACAGTGACCTACCCGTCTTATCAGCGGCTGGTTCAGCACAAAACGGACGGTGATAAAGGCTCAACCGACGTTGAAGGC
GATCTGGCAAGTAGCTGGAAAGCGTCTGACGATCAAAAAGAGTGGACGTTCACCCTGAAAGATAATGCTAAATTTGCCGA
TGGCACACCTGTCACTGCCGAAGCAGTAAAACTTTCTTTTGAGCGGCTACTAAAAATCGGCCAGGGGCCAGCAGAAGCAT
TTCCCAAAGATTTAAAGATTGATGCTCCCGACGAACATACGGTGAAGTTTACCCTTAGCCAACCATTCGCACCGTTCCTC
TACACGCTGGCGAATGACGGTGCATCCATTATCAATCCGGCGGTCTTAAAGGAACATGCAGCGGATGATGCTCGCGGCTT
CCTCGCGCAAAATACCGCCGGTTCCGGACCATTTATGCTGAAAAGCTGGCAAAAAGGTCAGCAATTAGTTCTGGTGCCAA
ATCCGCATTACCCAGGCAATAAACCGAACTTCAAACGGGTATCGGTAAAAATTATCGGTGAAAGTGCCTCCCGTCGCCTG
CAGCTCTCCCGTGGCGACATTGACATTGCCGATGCGCTGCCGGTGGATCAACTCAACGCCCTGAAGCAGGAAAATAAAGT
CAATGTGGCAGAGTATCCGTCACTGCGCGTTACCTATCTGTATCTGAATAACAGCAAAGCGCCTCTTAATCAGGCGGATC
TGCGTCGGGCCATTTCCTGGTCTACCGATTATCAGGGCATGGTTAACGGCATTCTGAGTGGTAACGGAAAACAGATGCGC
GGCCCGATTCCGGAAGGCATGTGGGGCTACGATGCGACGGCAATGCAATACAACCATGACGAAACGAAAGCCAAAGCCGA
ATGGGATAAAGTGACGAGCAAACCCACCAGCCTGACGTTTCTCTACTCCGATAACGATCCGAACTGGGAGCCTATTGCTT
TGGCGACACAATCCAGTCTCAACAAGCTGGGCATCAATGTGAAGCTGGAAAAGCTGGCGAACGCCACCATGCGCGACAGA
GTGGGTAAAGGTGATTACGACATTGCGATTGGCAACTGGAGTCCGGATTTTGCCGACCCGTATATGTTTATGAATTACTG
GTTTGAGTCAGACAAAAAAGGTCTGCCGGGTAACCGCTCGTTCTATGAAAACAGTGAGGTCGATAAGTTACTGCGCAATG
CGCTTGCGACCACCGACCAGACGCAGCGTACCCGGGACTACCAGCAGGCACAGAAAATCGTCATTGATGACGCTGCTTAT
GTGTACCTGTTCCAGAAAAACTACCAACTGGCGATGAACAAAGAGGTGAAAGGCTTTGTGTTCAATCCCATGCTGGAACA
GGTCTTCAATATCAATACCATGAGTAAATAA

Upstream 100 bases:

>100_bases
TTCGAATTACCCCAGGCAGCGAGTTACCCTCTGCTCGCTGATCAATTCTCTTGTTTTATATCCCCTGGCACACAGCACGT
CAGTTAATCAGGAAACTGTC

Downstream 100 bases:

>100_bases
CGTGACCTTCTGGAGTATTTTACGCCAACGCTGCTGGGGGCTGGTGCTCGTGGTGGCGGGCGTCTGCGTGATTACGTTTA
TTATCTCGCATCTGATCCCT

Product: D-ala-D-a la transporter subunit ; periplasmic-binding component of ABC superfamily

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 516; Mature: 516

Protein sequence:

>516_residues
MKRSISFRPTLLALVLATNFPVAHAAVPKDMLVIGKAADPQTLDPAVTIDNNDWTVTYPSYQRLVQHKTDGDKGSTDVEG
DLASSWKASDDQKEWTFTLKDNAKFADGTPVTAEAVKLSFERLLKIGQGPAEAFPKDLKIDAPDEHTVKFTLSQPFAPFL
YTLANDGASIINPAVLKEHAADDARGFLAQNTAGSGPFMLKSWQKGQQLVLVPNPHYPGNKPNFKRVSVKIIGESASRRL
QLSRGDIDIADALPVDQLNALKQENKVNVAEYPSLRVTYLYLNNSKAPLNQADLRRAISWSTDYQGMVNGILSGNGKQMR
GPIPEGMWGYDATAMQYNHDETKAKAEWDKVTSKPTSLTFLYSDNDPNWEPIALATQSSLNKLGINVKLEKLANATMRDR
VGKGDYDIAIGNWSPDFADPYMFMNYWFESDKKGLPGNRSFYENSEVDKLLRNALATTDQTQRTRDYQQAQKIVIDDAAY
VYLFQKNYQLAMNKEVKGFVFNPMLEQVFNINTMSK

Sequences:

>Translated_516_residues
MKRSISFRPTLLALVLATNFPVAHAAVPKDMLVIGKAADPQTLDPAVTIDNNDWTVTYPSYQRLVQHKTDGDKGSTDVEG
DLASSWKASDDQKEWTFTLKDNAKFADGTPVTAEAVKLSFERLLKIGQGPAEAFPKDLKIDAPDEHTVKFTLSQPFAPFL
YTLANDGASIINPAVLKEHAADDARGFLAQNTAGSGPFMLKSWQKGQQLVLVPNPHYPGNKPNFKRVSVKIIGESASRRL
QLSRGDIDIADALPVDQLNALKQENKVNVAEYPSLRVTYLYLNNSKAPLNQADLRRAISWSTDYQGMVNGILSGNGKQMR
GPIPEGMWGYDATAMQYNHDETKAKAEWDKVTSKPTSLTFLYSDNDPNWEPIALATQSSLNKLGINVKLEKLANATMRDR
VGKGDYDIAIGNWSPDFADPYMFMNYWFESDKKGLPGNRSFYENSEVDKLLRNALATTDQTQRTRDYQQAQKIVIDDAAY
VYLFQKNYQLAMNKEVKGFVFNPMLEQVFNINTMSK
>Mature_516_residues
MKRSISFRPTLLALVLATNFPVAHAAVPKDMLVIGKAADPQTLDPAVTIDNNDWTVTYPSYQRLVQHKTDGDKGSTDVEG
DLASSWKASDDQKEWTFTLKDNAKFADGTPVTAEAVKLSFERLLKIGQGPAEAFPKDLKIDAPDEHTVKFTLSQPFAPFL
YTLANDGASIINPAVLKEHAADDARGFLAQNTAGSGPFMLKSWQKGQQLVLVPNPHYPGNKPNFKRVSVKIIGESASRRL
QLSRGDIDIADALPVDQLNALKQENKVNVAEYPSLRVTYLYLNNSKAPLNQADLRRAISWSTDYQGMVNGILSGNGKQMR
GPIPEGMWGYDATAMQYNHDETKAKAEWDKVTSKPTSLTFLYSDNDPNWEPIALATQSSLNKLGINVKLEKLANATMRDR
VGKGDYDIAIGNWSPDFADPYMFMNYWFESDKKGLPGNRSFYENSEVDKLLRNALATTDQTQRTRDYQQAQKIVIDDAAY
VYLFQKNYQLAMNKEVKGFVFNPMLEQVFNINTMSK

Specific function: Part of the ABC transporter complex ddpABCDF, which is probably involved in D,D-dipeptide transport [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787762, Length=516, Percent_Identity=99.6124031007752, Blast_Score=1057, Evalue=0.0,
Organism=Escherichia coli, GI1789966, Length=524, Percent_Identity=26.7175572519084, Blast_Score=176, Evalue=5e-45,
Organism=Escherichia coli, GI87081878, Length=538, Percent_Identity=28.2527881040892, Blast_Score=159, Evalue=4e-40,
Organism=Escherichia coli, GI1787495, Length=518, Percent_Identity=26.4478764478764, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1787052, Length=521, Percent_Identity=26.295585412668, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI1789887, Length=526, Percent_Identity=25.0950570342205, Blast_Score=138, Evalue=7e-34,
Organism=Escherichia coli, GI1787551, Length=467, Percent_Identity=23.1263383297645, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1789397, Length=529, Percent_Identity=24.1965973534972, Blast_Score=109, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 57617; Mature: 57617

Theoretical pI: Translated: 6.82; Mature: 6.82

Prosite motif: PS01040 SBP_BACTERIAL_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRSISFRPTLLALVLATNFPVAHAAVPKDMLVIGKAADPQTLDPAVTIDNNDWTVTYPS
CCCCCCCCHHHHHHHHHCCCCCHHHCCCCCEEEEECCCCCCCCCCEEEEECCCEEEECHH
YQRLVQHKTDGDKGSTDVEGDLASSWKASDDQKEWTFTLKDNAKFADGTPVTAEAVKLSF
HHHHHHHCCCCCCCCCCCCCCHHCCCCCCCCCCEEEEEEECCCEECCCCCCHHHHHHHHH
ERLLKIGQGPAEAFPKDLKIDAPDEHTVKFTLSQPFAPFLYTLANDGASIINPAVLKEHA
HHHHHCCCCHHHHCCCCCEECCCCCCEEEEEECCCCHHHHHHHHCCCHHHCCHHHHHHHC
ADDARGFLAQNTAGSGPFMLKSWQKGQQLVLVPNPHYPGNKPNFKRVSVKIIGESASRRL
CCHHHCEEECCCCCCCCEEECCCCCCCEEEEECCCCCCCCCCCCEEEEEEEECCCCCCEE
QLSRGDIDIADALPVDQLNALKQENKVNVAEYPSLRVTYLYLNNSKAPLNQADLRRAISW
EEECCCEEHHCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHCC
STDYQGMVNGILSGNGKQMRGPIPEGMWGYDATAMQYNHDETKAKAEWDKVTSKPTSLTF
CCCCCHHHHHHHCCCCCEECCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEE
LYSDNDPNWEPIALATQSSLNKLGINVKLEKLANATMRDRVGKGDYDIAIGNWSPDFADP
EECCCCCCCCEEEEEEHHHHHHHCCCEEHHHHHCCHHHHHCCCCCEEEEECCCCCCCCCC
YMFMNYWFESDKKGLPGNRSFYENSEVDKLLRNALATTDQTQRTRDYQQAQKIVIDDAAY
HHEEHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHEEEECCEE
VYLFQKNYQLAMNKEVKGFVFNPMLEQVFNINTMSK
EEEEECCCEEEECCCCCCEEECHHHHHHHCCCCCCC
>Mature Secondary Structure
MKRSISFRPTLLALVLATNFPVAHAAVPKDMLVIGKAADPQTLDPAVTIDNNDWTVTYPS
CCCCCCCCHHHHHHHHHCCCCCHHHCCCCCEEEEECCCCCCCCCCEEEEECCCEEEECHH
YQRLVQHKTDGDKGSTDVEGDLASSWKASDDQKEWTFTLKDNAKFADGTPVTAEAVKLSF
HHHHHHHCCCCCCCCCCCCCCHHCCCCCCCCCCEEEEEEECCCEECCCCCCHHHHHHHHH
ERLLKIGQGPAEAFPKDLKIDAPDEHTVKFTLSQPFAPFLYTLANDGASIINPAVLKEHA
HHHHHCCCCHHHHCCCCCEECCCCCCEEEEEECCCCHHHHHHHHCCCHHHCCHHHHHHHC
ADDARGFLAQNTAGSGPFMLKSWQKGQQLVLVPNPHYPGNKPNFKRVSVKIIGESASRRL
CCHHHCEEECCCCCCCCEEECCCCCCCEEEEECCCCCCCCCCCCEEEEEEEECCCCCCEE
QLSRGDIDIADALPVDQLNALKQENKVNVAEYPSLRVTYLYLNNSKAPLNQADLRRAISW
EEECCCEEHHCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHCC
STDYQGMVNGILSGNGKQMRGPIPEGMWGYDATAMQYNHDETKAKAEWDKVTSKPTSLTF
CCCCCHHHHHHHCCCCCEECCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEE
LYSDNDPNWEPIALATQSSLNKLGINVKLEKLANATMRDRVGKGDYDIAIGNWSPDFADP
EECCCCCCCCEEEEEEHHHHHHHCCCEEHHHHHCCHHHHHCCCCCEEEEECCCCCCCCCC
YMFMNYWFESDKKGLPGNRSFYENSEVDKLLRNALATTDQTQRTRDYQQAQKIVIDDAAY
HHEEHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHEEEECCEE
VYLFQKNYQLAMNKEVKGFVFNPMLEQVFNINTMSK
EEEEECCCEEEECCCCCCEEECHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 9751644 [H]