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The map label for this gene is Rz

Identifier: 218694799

GI number: 218694799

Start: 1429836

End: 1430309

Strand: Direct

Name: Rz

Synonym: EC55989_1385

Alternate gene names: 218694799

Gene position: 1429836-1430309 (Clockwise)

Preceding gene: 218694798

Following gene: 218694800

Centisome position: 27.74

GC content: 50.63

Gene sequence:

>474_bases
TTGGGGGATAGATCAGTGAGCAGAGTCGCAGCGATTATTTATACTCTGGTTATCTGCACCATCGTCTGCCTGTCATGGGC
TGTTAATCATTACCGCGATAACGCCATTACCTACAAAGCCCAGCGCGACAAAAATGCCAGAGAACTGAAGCTGGCGAACG
TGGCAATTACTGACATGCAGATGCGTCAGCGTGATGTAGCAGAACTCGACGCCAGATACACAAAGGAGCTTGCTGATGCT
AACGCGACTATCGAAAGTCTTCGTGCTGATGTTTCTGCTGGGCGTAAGCGCCTGCAAGTCGCCGCCACCTGTGCAAAGTC
AACGACCGGAGCCAGCAGCATGGGCGATGGAGAAAGCCCAAGACTTACAGCAGATGCTGAACTCAATTATTACCGTCTCC
GAAGTGGAATCGACAAGTTAACCGCTCAGGTCAACTACCTGCAGGAGTACATCAGGACGCAGTGCTTAAAATAA

Upstream 100 bases:

>100_bases
TTCGCTGGTGGATAAAAGATGGTGGGCGCGATTGCCGCATACGTTCAAATAACTGCTATGGACAGGTTATTCGTCGTGAC
CAGGAAAGCGCATTAGCCTG

Downstream 100 bases:

>100_bases
TTTTAATTTCACTGAAATTTAATACGTGACTTTCAGGAAAATGCCTCGCAGATGCGGGGCATTTTTGTACAGGTATTTCA
CCGCGCACCGCAGCGCACTC

Product: Endopeptidase (Lysis protein Rz)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 157; Mature: 156

Protein sequence:

>157_residues
MGDRSVSRVAAIIYTLVICTIVCLSWAVNHYRDNAITYKAQRDKNARELKLANVAITDMQMRQRDVAELDARYTKELADA
NATIESLRADVSAGRKRLQVAATCAKSTTGASSMGDGESPRLTADAELNYYRLRSGIDKLTAQVNYLQEYIRTQCLK

Sequences:

>Translated_157_residues
MGDRSVSRVAAIIYTLVICTIVCLSWAVNHYRDNAITYKAQRDKNARELKLANVAITDMQMRQRDVAELDARYTKELADA
NATIESLRADVSAGRKRLQVAATCAKSTTGASSMGDGESPRLTADAELNYYRLRSGIDKLTAQVNYLQEYIRTQCLK
>Mature_156_residues
GDRSVSRVAAIIYTLVICTIVCLSWAVNHYRDNAITYKAQRDKNARELKLANVAITDMQMRQRDVAELDARYTKELADAN
ATIESLRADVSAGRKRLQVAATCAKSTTGASSMGDGESPRLTADAELNYYRLRSGIDKLTAQVNYLQEYIRTQCLK

Specific function: Necessary for host cell lysis. It is believed to code for an endopeptidase that cleaves the amino-carboxyl cross-link between the diaminopimelic acid and D-alanine residues in the murein component of the bacterial cell wall [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786769, Length=152, Percent_Identity=61.1842105263158, Blast_Score=165, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004929 [H]

Pfam domain/function: PF03245 Phage_lysis [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 17499; Mature: 17368

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDRSVSRVAAIIYTLVICTIVCLSWAVNHYRDNAITYKAQRDKNARELKLANVAITDMQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHH
MRQRDVAELDARYTKELADANATIESLRADVSAGRKRLQVAATCAKSTTGASSMGDGESP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
RLTADAELNYYRLRSGIDKLTAQVNYLQEYIRTQCLK
CEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GDRSVSRVAAIIYTLVICTIVCLSWAVNHYRDNAITYKAQRDKNARELKLANVAITDMQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHH
MRQRDVAELDARYTKELADANATIESLRADVSAGRKRLQVAATCAKSTTGASSMGDGESP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
RLTADAELNYYRLRSGIDKLTAQVNYLQEYIRTQCLK
CEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]