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The map label for this gene is torA

Identifier: 218694532

GI number: 218694532

Start: 1167923

End: 1170469

Strand: Direct

Name: torA

Synonym: EC55989_1107

Alternate gene names: 218694532

Gene position: 1167923-1170469 (Clockwise)

Preceding gene: 218694531

Following gene: 218694533

Centisome position: 22.66

GC content: 55.48

Gene sequence:

>2547_bases
ATGAACAATAACGATCTCTTTCAGGCATCACGTCGGCGTTTTCTGGCACAACTCGGCGGCTTAACCGTCGCCGGGATGCT
GGGGCCGTCATTGTTAACGCCGCGCCGTGCGACTGCGGCGCAAGCGGCGACTGACGCTGTCATCTCGAAAGAGGGCATTC
TTACCGGGTCGCACTGGGGGGCTATCCGCGCGACGGTGAAGGATGGTCGCTTTGTGGCGGCAAAACCGTTCGAACTGGAT
AAATATCCGTCGAAAATGATTGCCGGATTGCCGGATCACGTACACAACGCGGCGCGTATTCGTTATCCGATGGTACGCGT
GGACTGGCTGCGTAAGCGCCATCTCAGCGATACCTCCCAGCGCGGTGATAACCGTTTTGTGCGCGTGAGCTGGGATGAAG
CCCTCGACATGTTCTATGAAGAACTGGAACGCGTGCAGAAAACTCACGGGCCGAGTGCCTTGCTGACCGCCAGTGGTTGG
CAATCGACGGGGATGTTCCATAACGCTTCGGGGATGCTGGCGAAAGCTATTGCCTTGCATGGTAATAGCGTTGGTACGGG
CGGAGATTACTCTACCGGTGCTGCGCAGGTGATCCTGCCGCGCGTGGTTGGCTCAATGGAAGTGTATGAACAGCAAACCT
CCTGGCCGCTGGTATTGCAGAACAGCAAAACCATTGTGCTGTGGGGCTCTGATTTGCTGAAAAACCAGCAAGCGAACTGG
TGGTGCCCGGATCACGATGTTTATGAATATTACGCGCAGCTAAAAGCGAAAGTCGCCGCCGGTGAAATTGAGGTCATCAG
CATCGATCCGGTTGTCACATCCACCCATGAGTATCTGGGGCGCGAGCATGTGAAGCACATTGCGGTTAACCCGCAAACTG
ATGTGCCGCTGCAACTGGCGCTGGCGTATACGCTGTACAGTGAAAACCTGTACGACAAAAACTTCCTCGCTAACTACTGT
GTGGGTTTTGAGCAGTTCCTGCCGTACCTGCTGGGTGAGAAAGACGGTCAGCCGAAAGATGCCGCATGGGCTGAAAAACT
GACCGGCATTGATGCCGAAACCATTCGTGGGCTGGCGCGGCAGATGGCGGCGAACAGAACGCAAATTATTGCTGGCTGGT
GCGTGCAGCGTATGCAGCACGGTGAACAGTGGGCGTGGATGATTGTGGTTCTGGCGGCGATGCTGGGGCAAATTGGCCTG
CCAGGTGGTGGTTTTGGTTTTGGCTGGCACTACAACGGCGCAGGCACGCCGGGGCGTAAAGGCGTTATTCTGAGTGGTTT
CTCCGGCTCTACGTCGATTCCGCCTGTTCACGACAACAGTGACTACAAAGGCTACAGCAGCACTATTCCGATTGCCCGTT
TTATCGATGCGATCCTCGAACCGGGGAAAGTGATCAACTGGAACGGTAAATCGGTAAAACTGCCGCCGCTGAAAATGTGT
ATTTTTGCCGGAACTAACCCATTCCATCGCCATCAGCAGATCAACCGCATTATTGAAGGCTGGCGCAAGCTGGAAACGGT
TATCGCCATAGATAACCAGTGGACCTCAACCTGCCGCTTTGCCGATATCGTGCTGCCTGCGACCACGCAGTTTGAGCGTA
ACGATCTCGACCAGTACGGCAACCACTCCAACCGTGGCATTATCGCCATGAAACAGGTGGTGCCGCCGCAGTTCGAGGCG
CGCAACGACTTTGATATTTTCCGCGAGCTGTGCCGTCGCTTTAATCGCGAAGAAGCCTTTACCGAAGGGCTGGACGAAAT
GGGCTGGCTGAAACGCATCTGGCAGGAAGGTGTACAACAAGGCAAAGGACGCGGCGTTCATCTGCCAGCGTTTGATGACT
TCTGGAATAACAAAGAGTACGTCGAGTTTGACCATCCGCAGATGTTTGTTCGCCACCAGGCATTCCGCGAAGATCCGGAT
CTCGAACCGCTGGGCACGCCGAGTGGCCTGATTGAGATCTACTCGAAAACCATCGCCGATATGAACTACGACGATTGTCA
GGGGCATCCGATGTGGTTTGAGAAAATCGAACGCTCCCACGGTGGGCCCGGCTCGCAGAAGTATCCGTTGCATCTGCAAT
CTGTGCATCCGGATTTCCGACTTCACTCGCAGTTATGTGAGTCGGAAACTCTGCGTCAGCAATATACGGTAGCGGGTAAA
GAGCCAGTGTTCATTAACCCGCAGGATGCCAGCGCGCGCGGTATTCGTAACGGTGATGTGGTACGCGTCTTTAACGCTCG
CGGTCAGGTGTTGGCAGGGGCAGTAGTTTCTGACCGCTATGCACCCGGCGTGGCACGAATTCACGAAGGGGCATGGTACG
ATCCAGATAAAGGCGGCGAGCCTGGTGCGCTGTGCAAATACGGTAACCCCAACGTGCTGACCATCGACATCGGTACTTCG
CAGCTGGCGCAGGCGACCAGTGCGCACACTACGCTGGTGGAAATTGAGAAGTACAATGGAGCAGTGGAGCAGGTGACGGC
GTTTAACGGCCCTGTGGAGATGGTGGCGCAGTGCGAATATGTTCCCGCGTCGCAGGTGAAATCATGA

Upstream 100 bases:

>100_bases
GTCTCGATAAACGTGAAGAACGCACCTTGTTGAAATATCTGCAAATGAATGCGTCTGACACCGCAGGTAAGGCTCACGGC
GATAAGAAGGAAGAAAAATA

Downstream 100 bases:

>100_bases
CCACGCTGACAGCACAACAGATTGCCTGTGTTTACGCCTGGCTGGCGCAGTTGTTCTCCCGTGAACTGGACGATGAACAA
CTGACGCAAATCGCCAGTGC

Product: trimethylamine N-oxide (TMAO) reductase I, catalytic subunit

Products: NA

Alternate protein names: TMAO reductase 1; Trimethylamine oxidase 1 [H]

Number of amino acids: Translated: 848; Mature: 848

Protein sequence:

>848_residues
MNNNDLFQASRRRFLAQLGGLTVAGMLGPSLLTPRRATAAQAATDAVISKEGILTGSHWGAIRATVKDGRFVAAKPFELD
KYPSKMIAGLPDHVHNAARIRYPMVRVDWLRKRHLSDTSQRGDNRFVRVSWDEALDMFYEELERVQKTHGPSALLTASGW
QSTGMFHNASGMLAKAIALHGNSVGTGGDYSTGAAQVILPRVVGSMEVYEQQTSWPLVLQNSKTIVLWGSDLLKNQQANW
WCPDHDVYEYYAQLKAKVAAGEIEVISIDPVVTSTHEYLGREHVKHIAVNPQTDVPLQLALAYTLYSENLYDKNFLANYC
VGFEQFLPYLLGEKDGQPKDAAWAEKLTGIDAETIRGLARQMAANRTQIIAGWCVQRMQHGEQWAWMIVVLAAMLGQIGL
PGGGFGFGWHYNGAGTPGRKGVILSGFSGSTSIPPVHDNSDYKGYSSTIPIARFIDAILEPGKVINWNGKSVKLPPLKMC
IFAGTNPFHRHQQINRIIEGWRKLETVIAIDNQWTSTCRFADIVLPATTQFERNDLDQYGNHSNRGIIAMKQVVPPQFEA
RNDFDIFRELCRRFNREEAFTEGLDEMGWLKRIWQEGVQQGKGRGVHLPAFDDFWNNKEYVEFDHPQMFVRHQAFREDPD
LEPLGTPSGLIEIYSKTIADMNYDDCQGHPMWFEKIERSHGGPGSQKYPLHLQSVHPDFRLHSQLCESETLRQQYTVAGK
EPVFINPQDASARGIRNGDVVRVFNARGQVLAGAVVSDRYAPGVARIHEGAWYDPDKGGEPGALCKYGNPNVLTIDIGTS
QLAQATSAHTTLVEIEKYNGAVEQVTAFNGPVEMVAQCEYVPASQVKS

Sequences:

>Translated_848_residues
MNNNDLFQASRRRFLAQLGGLTVAGMLGPSLLTPRRATAAQAATDAVISKEGILTGSHWGAIRATVKDGRFVAAKPFELD
KYPSKMIAGLPDHVHNAARIRYPMVRVDWLRKRHLSDTSQRGDNRFVRVSWDEALDMFYEELERVQKTHGPSALLTASGW
QSTGMFHNASGMLAKAIALHGNSVGTGGDYSTGAAQVILPRVVGSMEVYEQQTSWPLVLQNSKTIVLWGSDLLKNQQANW
WCPDHDVYEYYAQLKAKVAAGEIEVISIDPVVTSTHEYLGREHVKHIAVNPQTDVPLQLALAYTLYSENLYDKNFLANYC
VGFEQFLPYLLGEKDGQPKDAAWAEKLTGIDAETIRGLARQMAANRTQIIAGWCVQRMQHGEQWAWMIVVLAAMLGQIGL
PGGGFGFGWHYNGAGTPGRKGVILSGFSGSTSIPPVHDNSDYKGYSSTIPIARFIDAILEPGKVINWNGKSVKLPPLKMC
IFAGTNPFHRHQQINRIIEGWRKLETVIAIDNQWTSTCRFADIVLPATTQFERNDLDQYGNHSNRGIIAMKQVVPPQFEA
RNDFDIFRELCRRFNREEAFTEGLDEMGWLKRIWQEGVQQGKGRGVHLPAFDDFWNNKEYVEFDHPQMFVRHQAFREDPD
LEPLGTPSGLIEIYSKTIADMNYDDCQGHPMWFEKIERSHGGPGSQKYPLHLQSVHPDFRLHSQLCESETLRQQYTVAGK
EPVFINPQDASARGIRNGDVVRVFNARGQVLAGAVVSDRYAPGVARIHEGAWYDPDKGGEPGALCKYGNPNVLTIDIGTS
QLAQATSAHTTLVEIEKYNGAVEQVTAFNGPVEMVAQCEYVPASQVKS
>Mature_848_residues
MNNNDLFQASRRRFLAQLGGLTVAGMLGPSLLTPRRATAAQAATDAVISKEGILTGSHWGAIRATVKDGRFVAAKPFELD
KYPSKMIAGLPDHVHNAARIRYPMVRVDWLRKRHLSDTSQRGDNRFVRVSWDEALDMFYEELERVQKTHGPSALLTASGW
QSTGMFHNASGMLAKAIALHGNSVGTGGDYSTGAAQVILPRVVGSMEVYEQQTSWPLVLQNSKTIVLWGSDLLKNQQANW
WCPDHDVYEYYAQLKAKVAAGEIEVISIDPVVTSTHEYLGREHVKHIAVNPQTDVPLQLALAYTLYSENLYDKNFLANYC
VGFEQFLPYLLGEKDGQPKDAAWAEKLTGIDAETIRGLARQMAANRTQIIAGWCVQRMQHGEQWAWMIVVLAAMLGQIGL
PGGGFGFGWHYNGAGTPGRKGVILSGFSGSTSIPPVHDNSDYKGYSSTIPIARFIDAILEPGKVINWNGKSVKLPPLKMC
IFAGTNPFHRHQQINRIIEGWRKLETVIAIDNQWTSTCRFADIVLPATTQFERNDLDQYGNHSNRGIIAMKQVVPPQFEA
RNDFDIFRELCRRFNREEAFTEGLDEMGWLKRIWQEGVQQGKGRGVHLPAFDDFWNNKEYVEFDHPQMFVRHQAFREDPD
LEPLGTPSGLIEIYSKTIADMNYDDCQGHPMWFEKIERSHGGPGSQKYPLHLQSVHPDFRLHSQLCESETLRQQYTVAGK
EPVFINPQDASARGIRNGDVVRVFNARGQVLAGAVVSDRYAPGVARIHEGAWYDPDKGGEPGALCKYGNPNVLTIDIGTS
QLAQATSAHTTLVEIEKYNGAVEQVTAFNGPVEMVAQCEYVPASQVKS

Specific function: Reduces trimethylamine-N-oxide (TMAO) into trimethylamine; an anaerobic reaction coupled to energy-yielding reactions [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787231, Length=848, Percent_Identity=99.6462264150943, Blast_Score=1764, Evalue=0.0,
Organism=Escherichia coli, GI87081994, Length=828, Percent_Identity=44.2028985507246, Blast_Score=667, Evalue=0.0,
Organism=Escherichia coli, GI145693196, Length=790, Percent_Identity=42.6582278481013, Blast_Score=615, Evalue=1e-177,
Organism=Escherichia coli, GI87081797, Length=759, Percent_Identity=32.0158102766798, Blast_Score=304, Evalue=1e-83,
Organism=Escherichia coli, GI1787870, Length=864, Percent_Identity=28.9351851851852, Blast_Score=273, Evalue=4e-74,
Organism=Escherichia coli, GI171474008, Length=751, Percent_Identity=29.9600532623169, Blast_Score=259, Evalue=5e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006658
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006655
- InterPro:   IPR006311
- InterPro:   IPR011887 [H]

Pfam domain/function: PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: =1.7.2.3 [H]

Molecular weight: Translated: 94526; Mature: 94526

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: PS00490 MOLYBDOPTERIN_PROK_2 ; PS00932 MOLYBDOPTERIN_PROK_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNNDLFQASRRRFLAQLGGLTVAGMLGPSLLTPRRATAAQAATDAVISKEGILTGSHWG
CCCCHHHHHHHHHHHHHHCCCEEEHHCCCHHCCCCHHHHHHHHHHHHHHCCCEEECCCCC
AIRATVKDGRFVAAKPFELDKYPSKMIAGLPDHVHNAARIRYPMVRVDWLRKRHLSDTSQ
EEEEEECCCEEEEECCCCCCCCHHHHHHCCCHHHCCHHHHCCCHHHHHHHHHHHCCCHHH
RGDNRFVRVSWDEALDMFYEELERVQKTHGPSALLTASGWQSTGMFHNASGMLAKAIALH
CCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEECCCCHHHHHHHHC
GNSVGTGGDYSTGAAQVILPRVVGSMEVYEQQTSWPLVLQNSKTIVLWGSDLLKNQQANW
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEECHHHHCCCCCCC
WCPDHDVYEYYAQLKAKVAAGEIEVISIDPVVTSTHEYLGREHVKHIAVNPQTDVPLQLA
CCCCCHHHHHHHHHHHHEECCEEEEEEECCCHHHHHHHHHHHHHHEEECCCCCCCCHHHH
LAYTLYSENLYDKNFLANYCVGFEQFLPYLLGEKDGQPKDAAWAEKLTGIDAETIRGLAR
HHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHH
QMAANRTQIIAGWCVQRMQHGEQWAWMIVVLAAMLGQIGLPGGGFGFGWHYNGAGTPGRK
HHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCC
GVILSGFSGSTSIPPVHDNSDYKGYSSTIPIARFIDAILEPGKVINWNGKSVKLPPLKMC
CEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEECCCCEEECCCEEEE
IFAGTNPFHRHQQINRIIEGWRKLETVIAIDNQWTSTCRFADIVLPATTQFERNDLDQYG
EEECCCHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCEEEEEEECCCCCCCHHHHHHHC
NHSNRGIIAMKQVVPPQFEARNDFDIFRELCRRFNREEAFTEGLDEMGWLKRIWQEGVQQ
CCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHCHHHHHHHHHHHHHHHHH
GKGRGVHLPAFDDFWNNKEYVEFDHPQMFVRHQAFREDPDLEPLGTPSGLIEIYSKTIAD
CCCCEEECCCHHHHCCCCCEEEECCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHC
MNYDDCQGHPMWFEKIERSHGGPGSQKYPLHLQSVHPDFRLHSQLCESETLRQQYTVAGK
CCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCC
EPVFINPQDASARGIRNGDVVRVFNARGQVLAGAVVSDRYAPGVARIHEGAWYDPDKGGE
CCEEECCCCCCCCCCCCCCEEEEECCCCCEEECHHHHCCCCCCHHHHCCCCCCCCCCCCC
PGALCKYGNPNVLTIDIGTSQLAQATSAHTTLVEIEKYNGAVEQVTAFNGPVEMVAQCEY
CCCEEECCCCCEEEEECCHHHHHHHHCCCEEEEEEEHHCCHHHHHHHCCCCHHHHHHCCC
VPASQVKS
CCHHHCCC
>Mature Secondary Structure
MNNNDLFQASRRRFLAQLGGLTVAGMLGPSLLTPRRATAAQAATDAVISKEGILTGSHWG
CCCCHHHHHHHHHHHHHHCCCEEEHHCCCHHCCCCHHHHHHHHHHHHHHCCCEEECCCCC
AIRATVKDGRFVAAKPFELDKYPSKMIAGLPDHVHNAARIRYPMVRVDWLRKRHLSDTSQ
EEEEEECCCEEEEECCCCCCCCHHHHHHCCCHHHCCHHHHCCCHHHHHHHHHHHCCCHHH
RGDNRFVRVSWDEALDMFYEELERVQKTHGPSALLTASGWQSTGMFHNASGMLAKAIALH
CCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEECCCCHHHHHHHHC
GNSVGTGGDYSTGAAQVILPRVVGSMEVYEQQTSWPLVLQNSKTIVLWGSDLLKNQQANW
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEECHHHHCCCCCCC
WCPDHDVYEYYAQLKAKVAAGEIEVISIDPVVTSTHEYLGREHVKHIAVNPQTDVPLQLA
CCCCCHHHHHHHHHHHHEECCEEEEEEECCCHHHHHHHHHHHHHHEEECCCCCCCCHHHH
LAYTLYSENLYDKNFLANYCVGFEQFLPYLLGEKDGQPKDAAWAEKLTGIDAETIRGLAR
HHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHH
QMAANRTQIIAGWCVQRMQHGEQWAWMIVVLAAMLGQIGLPGGGFGFGWHYNGAGTPGRK
HHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCC
GVILSGFSGSTSIPPVHDNSDYKGYSSTIPIARFIDAILEPGKVINWNGKSVKLPPLKMC
CEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEECCCCEEECCCEEEE
IFAGTNPFHRHQQINRIIEGWRKLETVIAIDNQWTSTCRFADIVLPATTQFERNDLDQYG
EEECCCHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCEEEEEEECCCCCCCHHHHHHHC
NHSNRGIIAMKQVVPPQFEARNDFDIFRELCRRFNREEAFTEGLDEMGWLKRIWQEGVQQ
CCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHCHHHHHHHHHHHHHHHHH
GKGRGVHLPAFDDFWNNKEYVEFDHPQMFVRHQAFREDPDLEPLGTPSGLIEIYSKTIAD
CCCCEEECCCHHHHCCCCCEEEECCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHC
MNYDDCQGHPMWFEKIERSHGGPGSQKYPLHLQSVHPDFRLHSQLCESETLRQQYTVAGK
CCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCC
EPVFINPQDASARGIRNGDVVRVFNARGQVLAGAVVSDRYAPGVARIHEGAWYDPDKGGE
CCEEECCCCCCCCCCCCCCEEEEECCCCCEEECHHHHCCCCCCHHHHCCCCCCCCCCCCC
PGALCKYGNPNVLTIDIGTSQLAQATSAHTTLVEIEKYNGAVEQVTAFNGPVEMVAQCEY
CCCEEECCCCCEEEEECCHHHHHHHHCCCEEEEEEEHHCCHHHHHHHCCCCHHHHHHCCC
VPASQVKS
CCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]