| Definition | Escherichia coli ED1a chromosome, complete genome. |
|---|---|
| Accession | NC_011745 |
| Length | 5,209,548 |
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The map label for this gene is hsdR [H]
Identifier: 218692733
GI number: 218692733
Start: 5146445
End: 5148877
Strand: Reverse
Name: hsdR [H]
Synonym: ECED1_5214
Alternate gene names: 218692733
Gene position: 5148877-5146445 (Counterclockwise)
Preceding gene: 218692735
Following gene: 218692732
Centisome position: 98.84
GC content: 49.49
Gene sequence:
>2433_bases ATGGCGGAACTGAACCTAAGTAACCTGACGGAAGCAGACATCATTACCAAATGCGTTATGCCAGCCATTCTCAATGCAGG CTGGGACAACACAACGCAAATCAGACAGGAGGTCAAACTCCGGGACGGTAAAGTCATCGTACGTGGTAAAGTTGCGGCAC GCAGAACAGTAAAATCTGCTGACATCGTGCTGTATCACAAACCAGGCATTCCCTTAGCCGTGATTGAAGCAAAAGCCAAC AAACATGAAATTGGCAAAGGGATGCAACAGGGCATTGAATATGCGCGCCTGCTGGACGTTCCTTTTGTTTTTGCCACCAA CGGGGATGGCTTTATCTTCCGCGATGCCACCGCAGCCGAAGGTGAATGCCTTGAAAAGCAAATAACGCTGGATGACTTCC CCTCCCCCGCTGAACTCTGGCAAAAATTCTGCCTCTGGAAAGGATACACACAAGCTCAGCTTCCGGTGATTACTCAGGAC TATTACGACGATGGCAGCGGTAAATCGCCACGTTATTACCAGCTTCAGGCAATCAACAAAACCATTGAAGCCGTCTCCAA CGGGCAAAACCGCGTTCTGCTGGTCATGGCGACCGGAACAGGGAAAACCTACACCGCATTCCAGATCATCTGGCGCCTGT GGAAATCAAAAAATAAAAAACGCATTTTGTTCCTTGCCGATCGCAACATTCTGGTCGACCAAACCAAAAATAATGATTTC CAGCCATTTGGTACGGCAATGACCAAAGTCAGCGGACGCACCATTGATCCCGCTTATGAAATTCACCTCGCGCTCTATCA GGCTATAACTGGCCCGGAGGAAGACCAAAAAGCGTTTAAACAAGTCGCACCAGATTTCTTCGATCTGATCGTGATCGACG AATGCCATCGCGGCAGCGCATCCGAAGACAGCGCCTGGCGAGAGATCCTTGATTATTTCAGTTCCGCCACCCAAATTGGC TTAACCGCCACGCCAAAAGAGACGCATGAAGTCTCCAGCACGGATTACTTCGGCGATCCGGTTTACGTCTACTCACTAAA AGAAGGGATCGAAGACGGCTTCCTCGCCCCTTATAAAGTTGTCCGTGTTGATATTGATGTTGATCTGCAAGGCTGGCGCC CAACCAAAGGGCAAACTGACTTAAACGGCGAAGTGATCGACGATCGTATCTATAACCAGAAAGATTTCGATCGCACGATG GTAATCGACGAACGCACAGAACTGGTTGCCAGAACCATTACCGACTACCTCAAGCGCACCAACCCGATGGATAAAACCAT CGTCTTCTGTAACGACATCGATCATGCAGAACGTATGCGCCGCGCCCTGGTGAATCTCAACCCGGAGCAGGTGAAAAAGA ACGACAAATACGTCATGAAAATCACCGGCGATGATGAAATTGGCAAAGCCCAGTTGGATAACTTCATCAACCCGAAAAAA GCATACCCGGTTATCGCGACCACTTCAGAACTGATGACCACTGGTGTGGATGCTAAAACCTGCAAACTGGTAGTACTGGA CCAGAACATCCAGTCGATGACCAAATTCAAGCAAATTATCGGTCGTGGTACACGCATCGACGAACGTTACGGCAAACTCT GGTTTACCATCCTCGACTTTAAAAAAGCCACCGAACTGTTTGCCGATGAGCGTTTCGATGGCATTCCCGAAAAAGTCATG GATACCACACCAGAGGATATCGCCGATCCAGAATCTGATTTTGAAGAGAAACTCGAAGAAATCAGCGAACATGACGACGA ACAGGTAACAGGCGTTGATGAACCGCCTGCGCCACCATACCAGGTTACCGATACCGATGATGTTGGCCCACTTCCGGAAG AAGACGAGAAGAAAATCCGCAAGTTTCACGTCAATGGCGTGGCGGTGGGTGTTATTGCGCAGCGTGTTCAGTATTACGAT GCCGACGGTAAACTGGTTACCGAATCTTTTAAAGATTACACCCGCAAAACACTGCTCAAAGAATATGCCTCGCTGGATGA CTTTACCCGCAAGTGGCAAGACGCCGATCGCAAAGAAGCGATCATTCACGAGCTGGAACAACAGGGGATCATCTGGGAAG TACTGGCAGAAGAAGTCGGTAAAGATCTCGACCCGTTCGACATGCTTTGCCACGTAGTGTATGGTCAGCCGCCGTTAACC CGCAAAGAGCGCGCCGAGAACGTGCGCAAGCGGAACTACTTCACAAAATACTCTGAAGCAGCGCAAGCCGTGCTCGATAA TCTGCTGGATAAATACGCCGATGCGGGCATACAGGAGATCGAAAGTATTCAGGTGCTGAAACTTAAACCATTCGACAGCA TGGGCACCCTACCGGAGATTATTAAAACCGGATTTGGCGACCGTAACGGGTATAATCAGGCGCTCAGCGAGCTGGAAAAC GAAATCTACCAATTACCGCCCCGCTCTGCTTAA
Upstream 100 bases:
>100_bases CTCTGCTACGTACTTCACGTTGAAACACCGCCCTAAGTCATAGCCAGGCTATTGATTTTATGTACAATCAGAATCGTCCT GATAAAAGCGAGAACACCCC
Downstream 100 bases:
>100_bases CAACTCTCTTTTGCGCCTTCTGCAACCATCATGTTGCAGAAGGCCTTGTTTTTCATGGAATACAACATGTCTATCAGTTC AGTAATCAAATCATTACAAG
Product: Type I restriction enzyme EcoAI R protein (R.EcoAI)
Products: NA
Alternate protein names: R.EcoAI [H]
Number of amino acids: Translated: 810; Mature: 809
Protein sequence:
>810_residues MAELNLSNLTEADIITKCVMPAILNAGWDNTTQIRQEVKLRDGKVIVRGKVAARRTVKSADIVLYHKPGIPLAVIEAKAN KHEIGKGMQQGIEYARLLDVPFVFATNGDGFIFRDATAAEGECLEKQITLDDFPSPAELWQKFCLWKGYTQAQLPVITQD YYDDGSGKSPRYYQLQAINKTIEAVSNGQNRVLLVMATGTGKTYTAFQIIWRLWKSKNKKRILFLADRNILVDQTKNNDF QPFGTAMTKVSGRTIDPAYEIHLALYQAITGPEEDQKAFKQVAPDFFDLIVIDECHRGSASEDSAWREILDYFSSATQIG LTATPKETHEVSSTDYFGDPVYVYSLKEGIEDGFLAPYKVVRVDIDVDLQGWRPTKGQTDLNGEVIDDRIYNQKDFDRTM VIDERTELVARTITDYLKRTNPMDKTIVFCNDIDHAERMRRALVNLNPEQVKKNDKYVMKITGDDEIGKAQLDNFINPKK AYPVIATTSELMTTGVDAKTCKLVVLDQNIQSMTKFKQIIGRGTRIDERYGKLWFTILDFKKATELFADERFDGIPEKVM DTTPEDIADPESDFEEKLEEISEHDDEQVTGVDEPPAPPYQVTDTDDVGPLPEEDEKKIRKFHVNGVAVGVIAQRVQYYD ADGKLVTESFKDYTRKTLLKEYASLDDFTRKWQDADRKEAIIHELEQQGIIWEVLAEEVGKDLDPFDMLCHVVYGQPPLT RKERAENVRKRNYFTKYSEAAQAVLDNLLDKYADAGIQEIESIQVLKLKPFDSMGTLPEIIKTGFGDRNGYNQALSELEN EIYQLPPRSA
Sequences:
>Translated_810_residues MAELNLSNLTEADIITKCVMPAILNAGWDNTTQIRQEVKLRDGKVIVRGKVAARRTVKSADIVLYHKPGIPLAVIEAKAN KHEIGKGMQQGIEYARLLDVPFVFATNGDGFIFRDATAAEGECLEKQITLDDFPSPAELWQKFCLWKGYTQAQLPVITQD YYDDGSGKSPRYYQLQAINKTIEAVSNGQNRVLLVMATGTGKTYTAFQIIWRLWKSKNKKRILFLADRNILVDQTKNNDF QPFGTAMTKVSGRTIDPAYEIHLALYQAITGPEEDQKAFKQVAPDFFDLIVIDECHRGSASEDSAWREILDYFSSATQIG LTATPKETHEVSSTDYFGDPVYVYSLKEGIEDGFLAPYKVVRVDIDVDLQGWRPTKGQTDLNGEVIDDRIYNQKDFDRTM VIDERTELVARTITDYLKRTNPMDKTIVFCNDIDHAERMRRALVNLNPEQVKKNDKYVMKITGDDEIGKAQLDNFINPKK AYPVIATTSELMTTGVDAKTCKLVVLDQNIQSMTKFKQIIGRGTRIDERYGKLWFTILDFKKATELFADERFDGIPEKVM DTTPEDIADPESDFEEKLEEISEHDDEQVTGVDEPPAPPYQVTDTDDVGPLPEEDEKKIRKFHVNGVAVGVIAQRVQYYD ADGKLVTESFKDYTRKTLLKEYASLDDFTRKWQDADRKEAIIHELEQQGIIWEVLAEEVGKDLDPFDMLCHVVYGQPPLT RKERAENVRKRNYFTKYSEAAQAVLDNLLDKYADAGIQEIESIQVLKLKPFDSMGTLPEIIKTGFGDRNGYNQALSELEN EIYQLPPRSA >Mature_809_residues AELNLSNLTEADIITKCVMPAILNAGWDNTTQIRQEVKLRDGKVIVRGKVAARRTVKSADIVLYHKPGIPLAVIEAKANK HEIGKGMQQGIEYARLLDVPFVFATNGDGFIFRDATAAEGECLEKQITLDDFPSPAELWQKFCLWKGYTQAQLPVITQDY YDDGSGKSPRYYQLQAINKTIEAVSNGQNRVLLVMATGTGKTYTAFQIIWRLWKSKNKKRILFLADRNILVDQTKNNDFQ PFGTAMTKVSGRTIDPAYEIHLALYQAITGPEEDQKAFKQVAPDFFDLIVIDECHRGSASEDSAWREILDYFSSATQIGL TATPKETHEVSSTDYFGDPVYVYSLKEGIEDGFLAPYKVVRVDIDVDLQGWRPTKGQTDLNGEVIDDRIYNQKDFDRTMV IDERTELVARTITDYLKRTNPMDKTIVFCNDIDHAERMRRALVNLNPEQVKKNDKYVMKITGDDEIGKAQLDNFINPKKA YPVIATTSELMTTGVDAKTCKLVVLDQNIQSMTKFKQIIGRGTRIDERYGKLWFTILDFKKATELFADERFDGIPEKVMD TTPEDIADPESDFEEKLEEISEHDDEQVTGVDEPPAPPYQVTDTDDVGPLPEEDEKKIRKFHVNGVAVGVIAQRVQYYDA DGKLVTESFKDYTRKTLLKEYASLDDFTRKWQDADRKEAIIHELEQQGIIWEVLAEEVGKDLDPFDMLCHVVYGQPPLTR KERAENVRKRNYFTKYSEAAQAVLDNLLDKYADAGIQEIESIQVLKLKPFDSMGTLPEIIKTGFGDRNGYNQALSELENE IYQLPPRSA
Specific function: The EcoAI enzyme recognizes 5'-GAGN(7)GTCA-3'. Subunit R is required for both nuclease and ATPase activities, but not for modification [H]
COG id: COG4096
COG function: function code V; Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 helicase C-terminal domain [H]
Homologues:
Organism=Escherichia coli, GI226510991, Length=635, Percent_Identity=26.6141732283465, Blast_Score=163, Evalue=4e-41, Organism=Escherichia coli, GI1788511, Length=424, Percent_Identity=24.0566037735849, Blast_Score=84, Evalue=5e-17,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR014001 - InterPro: IPR001650 - InterPro: IPR014021 - InterPro: IPR006935 - InterPro: IPR013670 - InterPro: IPR007409 [H]
Pfam domain/function: PF08463 EcoEI_R_C; PF04313 HSDR_N; PF04851 ResIII [H]
EC number: =3.1.21.3 [H]
Molecular weight: Translated: 92046; Mature: 91915
Theoretical pI: Translated: 4.71; Mature: 4.71
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.9 %Cys (Translated Protein) 1.7 %Met (Translated Protein) 2.6 %Cys+Met (Translated Protein) 0.9 %Cys (Mature Protein) 1.6 %Met (Mature Protein) 2.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MAELNLSNLTEADIITKCVMPAILNAGWDNTTQIRQEVKLRDGKVIVRGKVAARRTVKSA CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEEEECHHHHHHHCCC DIVLYHKPGIPLAVIEAKANKHEIGKGMQQGIEYARLLDVPFVFATNGDGFIFRDATAAE CEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEEECCCCCC GECLEKQITLDDFPSPAELWQKFCLWKGYTQAQLPVITQDYYDDGSGKSPRYYQLQAINK CHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCCEEEHHHHHH TIEAVSNGQNRVLLVMATGTGKTYTAFQIIWRLWKSKNKKRILFLADRNILVDQTKNNDF HHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEECCCEEEECCCCCCC QPFGTAMTKVSGRTIDPAYEIHLALYQAITGPEEDQKAFKQVAPDFFDLIVIDECHRGSA CCHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEEECCCCCCC SEDSAWREILDYFSSATQIGLTATPKETHEVSSTDYFGDPVYVYSLKEGIEDGFLAPYKV CCHHHHHHHHHHHHHHHHCCEECCCCHHHCCCCCCCCCCCEEEEEEHHCCCCCCCCCEEE VRVDIDVDLQGWRPTKGQTDLNGEVIDDRIYNQKDFDRTMVIDERTELVARTITDYLKRT EEEEEEEECCCCCCCCCCCCCCCCEEHHHHCCCCCCCCEEEECHHHHHHHHHHHHHHHHC NPMDKTIVFCNDIDHAERMRRALVNLNPEQVKKNDKYVMKITGDDEIGKAQLDNFINPKK CCCCCEEEEECCCCHHHHHHHHHHCCCHHHHCCCCCEEEEECCCCCCCHHHHHHCCCCCC AYPVIATTSELMTTGVDAKTCKLVVLDQNIQSMTKFKQIIGRGTRIDERYGKLWFTILDF CCCEEEEHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH KKATELFADERFDGIPEKVMDTTPEDIADPESDFEEKLEEISEHDDEQVTGVDEPPAPPY HHHHHHHHHHHCCCCCHHHHCCCCHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCE QVTDTDDVGPLPEEDEKKIRKFHVNGVAVGVIAQRVQYYDADGKLVTESFKDYTRKTLLK EECCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHH EYASLDDFTRKWQDADRKEAIIHELEQQGIIWEVLAEEVGKDLDPFDMLCHVVYGQPPLT HHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCC RKERAENVRKRNYFTKYSEAAQAVLDNLLDKYADAGIQEIESIQVLKLKPFDSMGTLPEI HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCEEEEEECCCCCCCCHHHH IKTGFGDRNGYNQALSELENEIYQLPPRSA HHCCCCCCCCHHHHHHHHHHHHHCCCCCCC >Mature Secondary Structure AELNLSNLTEADIITKCVMPAILNAGWDNTTQIRQEVKLRDGKVIVRGKVAARRTVKSA CCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEEEECHHHHHHHCCC DIVLYHKPGIPLAVIEAKANKHEIGKGMQQGIEYARLLDVPFVFATNGDGFIFRDATAAE CEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEEECCCCCC GECLEKQITLDDFPSPAELWQKFCLWKGYTQAQLPVITQDYYDDGSGKSPRYYQLQAINK CHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCCEEEHHHHHH TIEAVSNGQNRVLLVMATGTGKTYTAFQIIWRLWKSKNKKRILFLADRNILVDQTKNNDF HHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEECCCEEEECCCCCCC QPFGTAMTKVSGRTIDPAYEIHLALYQAITGPEEDQKAFKQVAPDFFDLIVIDECHRGSA CCHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEEECCCCCCC SEDSAWREILDYFSSATQIGLTATPKETHEVSSTDYFGDPVYVYSLKEGIEDGFLAPYKV CCHHHHHHHHHHHHHHHHCCEECCCCHHHCCCCCCCCCCCEEEEEEHHCCCCCCCCCEEE VRVDIDVDLQGWRPTKGQTDLNGEVIDDRIYNQKDFDRTMVIDERTELVARTITDYLKRT EEEEEEEECCCCCCCCCCCCCCCCEEHHHHCCCCCCCCEEEECHHHHHHHHHHHHHHHHC NPMDKTIVFCNDIDHAERMRRALVNLNPEQVKKNDKYVMKITGDDEIGKAQLDNFINPKK CCCCCEEEEECCCCHHHHHHHHHHCCCHHHHCCCCCEEEEECCCCCCCHHHHHHCCCCCC AYPVIATTSELMTTGVDAKTCKLVVLDQNIQSMTKFKQIIGRGTRIDERYGKLWFTILDF CCCEEEEHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH KKATELFADERFDGIPEKVMDTTPEDIADPESDFEEKLEEISEHDDEQVTGVDEPPAPPY HHHHHHHHHHHCCCCCHHHHCCCCHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCE QVTDTDDVGPLPEEDEKKIRKFHVNGVAVGVIAQRVQYYDADGKLVTESFKDYTRKTLLK EECCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHH EYASLDDFTRKWQDADRKEAIIHELEQQGIIWEVLAEEVGKDLDPFDMLCHVVYGQPPLT HHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCC RKERAENVRKRNYFTKYSEAAQAVLDNLLDKYADAGIQEIESIQVLKLKPFDSMGTLPEI HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCEEEEEECCCCCCCCHHHH IKTGFGDRNGYNQALSELENEIYQLPPRSA HHCCCCCCCCHHHHHHHHHHHHHCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8412658 [H]