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The map label for this gene is insK [C]

Identifier: 218692551

GI number: 218692551

Start: 4956276

End: 4957166

Strand: Reverse

Name: insK [C]

Synonym: ECED1_5013

Alternate gene names: 218692551

Gene position: 4957166-4956276 (Counterclockwise)

Preceding gene: 218692552

Following gene: 218692544

Centisome position: 95.16

GC content: 54.21

Gene sequence:

>891_bases
GTGATGCCACTGCTGGATAAGCTGCGTGAGCAGTACGGGGTCGGACCGCTATGCAGCGAACTGCATATTGCCCCGTCAAC
GTATTACCACTGTCAGCAACAGCGACATCATCCGGATAAACGCAGTGCCCGTGCGCAGCGCGATAACTGGCTGAAGAAAG
AGATACAGCGCGTATACGATGAAAATCACAAGGTATACGGTGTGCGTAAAGTCTGGCGTCAGTTGTTACGGGAAGGTATC
AGAGTGGCCAGATGCACTGTGGCACGTCTCATGGCGGTTATGGGACTTGCCGGTGTTCTCCGGGGTAAAAAGGTCCGTAC
GACCATCAGCCGGAAAGCCGTTGCCGCAGGCGACCACGTAAACCGTCAGTTCGTGGCAGAACGACCTGACCAGCTGTGGG
TGGCTGATTTTACTTACGTCAGCACATGGCGGGGCTTCGTCTATGTGGCGTTCATCATTGATGTGTTTGCCGGATACATC
GTGGGGTGGCGGGTCTCATCGTCCATGGAAACGACATTCGTGCCGGATGCACTGGAGCAGGCGTTATGGGCCCGTCGACC
GTCCGGCACGGTCCATCACAGTGATAAAGGTTCTCAGTATGTATCGCTGGCCTACACACAGCGGCTTAAGGAAGCCGGAT
TACTGGCATCAACAGGAAGTACAGGCGACTCGTATGACAACGCGATGGCGGAGAGCATCAATGGTCTTTACAAAGCGGAG
GTAATACACCGTAAGAGCTGGAAAAACCGTGCAGAAGTGGAACTGGCCACACTCACGTGGGTGGACTGGTATAACAATCG
ACGATTGCTGGGAAGGCTGGGCCATACTCCTCCGGCAGAAGCAGAAAAAGCTTATTATGCTTCCATCGGAAACAATGATC
TGGCAGCCTGA

Upstream 100 bases:

>100_bases
AGCTGGAGCGTGAAAATCGCGAACTGCGCCGCAGTAACGATATCCTTCGCCAGGCTTCCGCTTATTTTGCGAAGGCGGAG
TTCGACCGCCTCTGGAAAAA

Downstream 100 bases:

>100_bases
GTTCACAGATAAAACACTCTCCAGGAAACCCGGGGCGGTTCATAAACTGACCGCCGTATGTAGCCATGATGCCAGTATTG
GTAACGTAGGTGCCCACCTT

Product: transposase ORF B, IS629

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MMPLLDKLREQYGVGPLCSELHIAPSTYYHCQQQRHHPDKRSARAQRDNWLKKEIQRVYDENHKVYGVRKVWRQLLREGI
RVARCTVARLMAVMGLAGVLRGKKVRTTISRKAVAAGDHVNRQFVAERPDQLWVADFTYVSTWRGFVYVAFIIDVFAGYI
VGWRVSSSMETTFVPDALEQALWARRPSGTVHHSDKGSQYVSLAYTQRLKEAGLLASTGSTGDSYDNAMAESINGLYKAE
VIHRKSWKNRAEVELATLTWVDWYNNRRLLGRLGHTPPAEAEKAYYASIGNNDLAA

Sequences:

>Translated_296_residues
MMPLLDKLREQYGVGPLCSELHIAPSTYYHCQQQRHHPDKRSARAQRDNWLKKEIQRVYDENHKVYGVRKVWRQLLREGI
RVARCTVARLMAVMGLAGVLRGKKVRTTISRKAVAAGDHVNRQFVAERPDQLWVADFTYVSTWRGFVYVAFIIDVFAGYI
VGWRVSSSMETTFVPDALEQALWARRPSGTVHHSDKGSQYVSLAYTQRLKEAGLLASTGSTGDSYDNAMAESINGLYKAE
VIHRKSWKNRAEVELATLTWVDWYNNRRLLGRLGHTPPAEAEKAYYASIGNNDLAA
>Mature_296_residues
MMPLLDKLREQYGVGPLCSELHIAPSTYYHCQQQRHHPDKRSARAQRDNWLKKEIQRVYDENHKVYGVRKVWRQLLREGI
RVARCTVARLMAVMGLAGVLRGKKVRTTISRKAVAAGDHVNRQFVAERPDQLWVADFTYVSTWRGFVYVAFIIDVFAGYI
VGWRVSSSMETTFVPDALEQALWARRPSGTVHHSDKGSQYVSLAYTQRLKEAGLLASTGSTGDSYDNAMAESINGLYKAE
VIHRKSWKNRAEVELATLTWVDWYNNRRLLGRLGHTPPAEAEKAYYASIGNNDLAA

Specific function: Involved in the transposition of the insertion sequence [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=260, Percent_Identity=50, Blast_Score=249, Evalue=2e-66,
Organism=Escherichia coli, GI1789981, Length=286, Percent_Identity=30.0699300699301, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1788405, Length=282, Percent_Identity=27.6595744680851, Blast_Score=111, Evalue=7e-26,
Organism=Escherichia coli, GI1787263, Length=282, Percent_Identity=27.6595744680851, Blast_Score=111, Evalue=7e-26,
Organism=Escherichia coli, GI1786753, Length=282, Percent_Identity=27.6595744680851, Blast_Score=111, Evalue=7e-26,
Organism=Escherichia coli, GI1786570, Length=282, Percent_Identity=27.6595744680851, Blast_Score=111, Evalue=7e-26,
Organism=Escherichia coli, GI1786490, Length=282, Percent_Identity=27.6595744680851, Blast_Score=111, Evalue=7e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 33700; Mature: 33700

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMPLLDKLREQYGVGPLCSELHIAPSTYYHCQQQRHHPDKRSARAQRDNWLKKEIQRVYD
CCHHHHHHHHHHCCCCCHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
ENHKVYGVRKVWRQLLREGIRVARCTVARLMAVMGLAGVLRGKKVRTTISRKAVAAGDHV
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC
NRQFVAERPDQLWVADFTYVSTWRGFVYVAFIIDVFAGYIVGWRVSSSMETTFVPDALEQ
CHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHH
ALWARRPSGTVHHSDKGSQYVSLAYTQRLKEAGLLASTGSTGDSYDNAMAESINGLYKAE
HHHHCCCCCCCEECCCCCCEEHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHH
VIHRKSWKNRAEVELATLTWVDWYNNRRLLGRLGHTPPAEAEKAYYASIGNNDLAA
HHHHHHCCCCCCEEEEEEEEEHHCCCCHHHHHCCCCCCCCHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MMPLLDKLREQYGVGPLCSELHIAPSTYYHCQQQRHHPDKRSARAQRDNWLKKEIQRVYD
CCHHHHHHHHHHCCCCCHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
ENHKVYGVRKVWRQLLREGIRVARCTVARLMAVMGLAGVLRGKKVRTTISRKAVAAGDHV
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC
NRQFVAERPDQLWVADFTYVSTWRGFVYVAFIIDVFAGYIVGWRVSSSMETTFVPDALEQ
CHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHH
ALWARRPSGTVHHSDKGSQYVSLAYTQRLKEAGLLASTGSTGDSYDNAMAESINGLYKAE
HHHHCCCCCCCEECCCCCCEEHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHH
VIHRKSWKNRAEVELATLTWVDWYNNRRLLGRLGHTPPAEAEKAYYASIGNNDLAA
HHHHHHCCCCCCEEEEEEEEEHHCCCCHHHHHCCCCCCCCHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2159625; 2824781 [H]