Click here to switch to the map view.

The map label for this gene is ptsG [H]

Identifier: 218692544

GI number: 218692544

Start: 4949479

End: 4951080

Strand: Reverse

Name: ptsG [H]

Synonym: ECED1_5002

Alternate gene names: 218692544

Gene position: 4951080-4949479 (Counterclockwise)

Preceding gene: 218692551

Following gene: 218692543

Centisome position: 95.04

GC content: 51.75

Gene sequence:

>1602_bases
ATGATTACGGTGAAAATTTTCATTAATAATCGAGGAGATGATAAAATGATGCAAATGTTTAGCTGCGCTTCATCGGGGGG
ATGGTTTGAAAAAGCGCAGCGGTTCGGCAAATCGTTCATGCTGCCGATTGCGGTATTGCCCGCAGCGGGGTTGTTGTTGG
GGATTGGTGGGGCTCTGTCGAATCCCAATACGCTGACGGCCTACCCATTCTTGAATGTCGACTGGCTGCAGGCAATCTTC
ACAATCATGACCAGCGCAGGTTCTATTGTGTTTGCCAACCTGTCGGTACTCTTTGCGGTCGGCGTCGCCGTAGGGCTGGC
GAAATCGGATAAAGGCACTGCCGGGCTTGCGGCATTGCTAGCGTTTCTGGTGATGAATGCTACCATCAACGCCTTATTAA
CGCTAAATGGAACGTTGGCGCACAAGAACCCCGGTTCAGTTGGCCAGGGGATGACACTTGGTATTCAGACACTGGAAACT
GGTGTGTTTGGTGGGGTGGTGATTGGTCTCGTCACCTGCACGTTACATAGCCGTTTCAATAAAGTCTCACTACCTCAGTT
TCTCGGTTTTTTTAGTGGTTCTCGTTTTGTACCCATTATCAGCTCCCTTGCCGCGATAGTAGTGGGTGCGGTTATGACGG
TGGTGTGGCCGCATTTCCAGAAACTCATTTTTGGACTGGGCGGCCTGGTGGATGCAACGGGCTATCTGGGGACGCTGTTG
TACGGCTTCATCCTGCGTATGCTTGGTCCACTGGGTTTACACCATATCTTTTATTTGCCGTTCTGGACGACGGCGCTGGG
CGGCAGTGAAATCGTCAACGGCCAGTTGGTTGAAGGTACGCAGCGGATTTTCTTTGCCCAACTTGCCGATCCGAATACGC
AGCAGTTCTACGCGGGTACCGCTCGCTTTATGTCCGGGCGCTTTATCACCATGATGTTTGGCCTGCTTGGCGCATGTCTG
GCAATGTACCATACCGCAAAGCCGGAGAATAGAAAGGTTGTCGCCGGACTACTTTTGTCGGCAGCCTTGACCTCTTTCCT
GACGGGAATCACTGAGCCTGTTGAGTTCTCCTTCCTGTTTGTCGCGCCCGTATTATACGTAATTCACGCCTTCTTCGATG
GTCTGGCGTTTATGGTCGCCCATATTTTACATATCACTATTGGGCAAACCTTTTCGGGCGGGCTTATCGATTTCCTTCTC
TTCGGCGTGTTGCAGGGGGAATCTAAAACAAACTGGATGTATGTCCCCATAGTGGGAATACCGTGGTTCTTCCTTTACTA
CTTCACTTTCCGCTATTTGATTAACCGCTTTGGCTGGCTGACGCCGGGTCGTGAGAACGTAACCCTGGTTGAATCCGGCC
AGCCTCAGAGTGAACGCGCAGCGGCAGTCATTGCCGGGCTGGGAGGCAAAGAGAATCTGGAAGAGGTGGACTGTTGCGCC
ACGCGCCTGCGCGTGACGGTTAAAGAGAGCAGTAAGGTAGATGAAGCTGCGCTGAAAGTGACCGGAGCGCGTGGCGTGAT
TATTCGCGGCAACGGCGTTCAGGTGATTTATGGCCCTCATGTCACCATCATTAAAAACGAAGTCGAAGAGATTTTATCGT
AA

Upstream 100 bases:

>100_bases
TCTGTTGATAGTGTGGCGGAAAGGAGGGGATTGATGCCAGACATTTTAAAAAAAGTATGATCGACTTCTTGTATTTTGAT
GGTTATTTTCATTTATAAGA

Downstream 100 bases:

>100_bases
TGAAAACTGTACTGGATTCCCTGAAAGGTAAATTAATCGTCTCCTGTCAGGCTCTGGAAAATGAGCCTCTACATAGTCCG
TTTATTATGTCACGTATGGC

Product: PTS system glucose-specific enzyme II, ABC component

Products: NA

Alternate protein names: EII-Glc/EIII-Glc; EIICBA-Glc; Glucose permease IIC component; PTS system glucose-specific EIIC component; Glucose-specific phosphotransferase enzyme IIB component; PTS system glucose-specific EIIB component; Glucose-specific phosphotransferase enzyme IIA component; PTS system glucose-specific EIIA component [H]

Number of amino acids: Translated: 533; Mature: 533

Protein sequence:

>533_residues
MITVKIFINNRGDDKMMQMFSCASSGGWFEKAQRFGKSFMLPIAVLPAAGLLLGIGGALSNPNTLTAYPFLNVDWLQAIF
TIMTSAGSIVFANLSVLFAVGVAVGLAKSDKGTAGLAALLAFLVMNATINALLTLNGTLAHKNPGSVGQGMTLGIQTLET
GVFGGVVIGLVTCTLHSRFNKVSLPQFLGFFSGSRFVPIISSLAAIVVGAVMTVVWPHFQKLIFGLGGLVDATGYLGTLL
YGFILRMLGPLGLHHIFYLPFWTTALGGSEIVNGQLVEGTQRIFFAQLADPNTQQFYAGTARFMSGRFITMMFGLLGACL
AMYHTAKPENRKVVAGLLLSAALTSFLTGITEPVEFSFLFVAPVLYVIHAFFDGLAFMVAHILHITIGQTFSGGLIDFLL
FGVLQGESKTNWMYVPIVGIPWFFLYYFTFRYLINRFGWLTPGRENVTLVESGQPQSERAAAVIAGLGGKENLEEVDCCA
TRLRVTVKESSKVDEAALKVTGARGVIIRGNGVQVIYGPHVTIIKNEVEEILS

Sequences:

>Translated_533_residues
MITVKIFINNRGDDKMMQMFSCASSGGWFEKAQRFGKSFMLPIAVLPAAGLLLGIGGALSNPNTLTAYPFLNVDWLQAIF
TIMTSAGSIVFANLSVLFAVGVAVGLAKSDKGTAGLAALLAFLVMNATINALLTLNGTLAHKNPGSVGQGMTLGIQTLET
GVFGGVVIGLVTCTLHSRFNKVSLPQFLGFFSGSRFVPIISSLAAIVVGAVMTVVWPHFQKLIFGLGGLVDATGYLGTLL
YGFILRMLGPLGLHHIFYLPFWTTALGGSEIVNGQLVEGTQRIFFAQLADPNTQQFYAGTARFMSGRFITMMFGLLGACL
AMYHTAKPENRKVVAGLLLSAALTSFLTGITEPVEFSFLFVAPVLYVIHAFFDGLAFMVAHILHITIGQTFSGGLIDFLL
FGVLQGESKTNWMYVPIVGIPWFFLYYFTFRYLINRFGWLTPGRENVTLVESGQPQSERAAAVIAGLGGKENLEEVDCCA
TRLRVTVKESSKVDEAALKVTGARGVIIRGNGVQVIYGPHVTIIKNEVEEILS
>Mature_533_residues
MITVKIFINNRGDDKMMQMFSCASSGGWFEKAQRFGKSFMLPIAVLPAAGLLLGIGGALSNPNTLTAYPFLNVDWLQAIF
TIMTSAGSIVFANLSVLFAVGVAVGLAKSDKGTAGLAALLAFLVMNATINALLTLNGTLAHKNPGSVGQGMTLGIQTLET
GVFGGVVIGLVTCTLHSRFNKVSLPQFLGFFSGSRFVPIISSLAAIVVGAVMTVVWPHFQKLIFGLGGLVDATGYLGTLL
YGFILRMLGPLGLHHIFYLPFWTTALGGSEIVNGQLVEGTQRIFFAQLADPNTQQFYAGTARFMSGRFITMMFGLLGACL
AMYHTAKPENRKVVAGLLLSAALTSFLTGITEPVEFSFLFVAPVLYVIHAFFDGLAFMVAHILHITIGQTFSGGLIDFLL
FGVLQGESKTNWMYVPIVGIPWFFLYYFTFRYLINRFGWLTPGRENVTLVESGQPQSERAAAVIAGLGGKENLEEVDCCA
TRLRVTVKESSKVDEAALKVTGARGVIIRGNGVQVIYGPHVTIIKNEVEEILS

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787908, Length=516, Percent_Identity=43.0232558139535, Blast_Score=389, Evalue=1e-109,
Organism=Escherichia coli, GI1787343, Length=504, Percent_Identity=43.0555555555556, Blast_Score=365, Evalue=1e-102,
Organism=Escherichia coli, GI1786894, Length=513, Percent_Identity=35.672514619883, Blast_Score=258, Evalue=7e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001127
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011299 [H]

Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 57393; Mature: 57393

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITVKIFINNRGDDKMMQMFSCASSGGWFEKAQRFGKSFMLPIAVLPAAGLLLGIGGALS
CEEEEEEEECCCCHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCC
NPNTLTAYPFLNVDWLQAIFTIMTSAGSIVFANLSVLFAVGVAVGLAKSDKGTAGLAALL
CCCCEEEECCCCHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
AFLVMNATINALLTLNGTLAHKNPGSVGQGMTLGIQTLETGVFGGVVIGLVTCTLHSRFN
HHHHHHHHHHEEEEECCEEECCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCC
KVSLPQFLGFFSGSRFVPIISSLAAIVVGAVMTVVWPHFQKLIFGLGGLVDATGYLGTLL
CCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
YGFILRMLGPLGLHHIFYLPFWTTALGGSEIVNGQLVEGTQRIFFAQLADPNTQQFYAGT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCEEECCHHHEEEEECCCCCCHHHHHHH
ARFMSGRFITMMFGLLGACLAMYHTAKPENRKVVAGLLLSAALTSFLTGITEPVEFSFLF
HHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
VAPVLYVIHAFFDGLAFMVAHILHITIGQTFSGGLIDFLLFGVLQGESKTNWMYVPIVGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEHHH
PWFFLYYFTFRYLINRFGWLTPGRENVTLVESGQPQSERAAAVIAGLGGKENLEEVDCCA
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHEECCCCCCCHHHHHHHH
TRLRVTVKESSKVDEAALKVTGARGVIIRGNGVQVIYGPHVTIIKNEVEEILS
HHHEEEECCCCCHHHHHHEEECCCEEEEECCCEEEEECCEEEEEHHHHHHHCC
>Mature Secondary Structure
MITVKIFINNRGDDKMMQMFSCASSGGWFEKAQRFGKSFMLPIAVLPAAGLLLGIGGALS
CEEEEEEEECCCCHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCC
NPNTLTAYPFLNVDWLQAIFTIMTSAGSIVFANLSVLFAVGVAVGLAKSDKGTAGLAALL
CCCCEEEECCCCHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
AFLVMNATINALLTLNGTLAHKNPGSVGQGMTLGIQTLETGVFGGVVIGLVTCTLHSRFN
HHHHHHHHHHEEEEECCEEECCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCC
KVSLPQFLGFFSGSRFVPIISSLAAIVVGAVMTVVWPHFQKLIFGLGGLVDATGYLGTLL
CCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
YGFILRMLGPLGLHHIFYLPFWTTALGGSEIVNGQLVEGTQRIFFAQLADPNTQQFYAGT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCEEECCHHHEEEEECCCCCCHHHHHHH
ARFMSGRFITMMFGLLGACLAMYHTAKPENRKVVAGLLLSAALTSFLTGITEPVEFSFLF
HHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
VAPVLYVIHAFFDGLAFMVAHILHITIGQTFSGGLIDFLLFGVLQGESKTNWMYVPIVGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEHHH
PWFFLYYFTFRYLINRFGWLTPGRENVTLVESGQPQSERAAAVIAGLGGKENLEEVDCCA
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHEECCCCCCCHHHHHHHH
TRLRVTVKESSKVDEAALKVTGARGVIIRGNGVQVIYGPHVTIIKNEVEEILS
HHHEEEECCCCCHHHHHHEEECCCEEEEECCCEEEEECCEEEEEHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1508157; 9384377; 2497294; 2120236; 1911744; 1906345; 9593197 [H]