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The map label for this gene is basS [H]

Identifier: 218692408

GI number: 218692408

Start: 4808954

End: 4810045

Strand: Reverse

Name: basS [H]

Synonym: ECED1_4846

Alternate gene names: 218692408

Gene position: 4810045-4808954 (Counterclockwise)

Preceding gene: 218692409

Following gene: 218692404

Centisome position: 92.33

GC content: 53.75

Gene sequence:

>1092_bases
ATGCGTTTTCTGCGCCGACCAATATCGCTGCGCCAACGGCTGATATTGACCATCGGGGCCATTTTGTTGGTGTTTGAGCT
GATCAGCGTCTTCTGGCTGTGGCATGAAAGTACCGAGCAGATTCAGCTGTTTGAGCAGGCGCTACGCGACAATCGCAACA
ACGATCGCCACATCATGCGTGAGATCCGCGAGGCGGTCGCCAGCCTGATTGTCCCCGGCGTCTTTATGGTTAGCCTGACG
CTATTTATCTGCTATCAGGCGGTACGCCGCATCACCCGACCGCTGGCGGAGCTGCAAAAAGAGCTGGAAGCGCGCACCGC
CGATAACTTAACGCCCATTGCCATTCATAGCGCCACCCTCGAAATCGATGCGGTGGTTTCGGCATTAAACGATCTGGTCA
GTCGCCTGACCAGCACGCTGGATAACGAAAGGTTGTTTACCGCTGACGTCGCGCACGAACTGCGAACGCCACTGGCGGGG
GTGCGTTTGCATCTGGAACTGCTGGCGAAAACGCATCACATTGATGTAGCACCGTTAGTGGCACGACTTGATCAGATGAT
GGAGAGCGTCTCCCAGCTGCTGCAACTGGCGCGTGCCGGACAGTCATTTTCTTCCGGTAATTATCAACATGTAAAACTGC
TGGAAGATGTCATTCTCCCCTCGTATGACGAACTCAGTACCATGCTCGACCAGCGCCAGCAAACCCTGCTATTGCCAGAG
AGCGCCGCCGACATCACCGTTCAGGGTGATGCAACCCTGCTGCGGATGTTATTGCGAAACCTGGTAGAAAACGCCCATCG
TTATAGCCCGCAAGGCAGCAACATTATGATTAAGCTGCAAGAAGATGGCGGAGCGATCATGGCCGTTGAAGATGAAGGAC
CGGGTATTGATGAGAGTAAATGCGGGGAGTTGAGTAAAGCGTTTGTACGAATGGACAGCCGTTATGGCGGAATTGGTCTG
GGGTTAAGTATTGTCAGCCGCATTACACAGTTGCATCACGGGCAGTTTTTCCTGCAAAACCGGCAAGAGACTTCCGGCAC
GCGGGCCTGGATACGGCTGAAAAAAGATCAGTACGTGGCAAACCAGATATAA

Upstream 100 bases:

>100_bases
TATCCATAACCTGCGCGACAAAGTGGGCAAAGCCCGTATCCGCACCGTGCGCGGATTTGGCTATATGCTGGTCGCAAATG
AGGAAAACTAATTGAATCTG

Downstream 100 bases:

>100_bases
AGAAAGCTGCTGACCACCAGCACGCTGAACACGGTAGTTAAACTTTCATAAACACGGTTTTTCATTGTACTCTCCTCCGT
TAACCTGGAGGAGAGTATGC

Product: sensor protein BasS/PmrB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MRFLRRPISLRQRLILTIGAILLVFELISVFWLWHESTEQIQLFEQALRDNRNNDRHIMREIREAVASLIVPGVFMVSLT
LFICYQAVRRITRPLAELQKELEARTADNLTPIAIHSATLEIDAVVSALNDLVSRLTSTLDNERLFTADVAHELRTPLAG
VRLHLELLAKTHHIDVAPLVARLDQMMESVSQLLQLARAGQSFSSGNYQHVKLLEDVILPSYDELSTMLDQRQQTLLLPE
SAADITVQGDATLLRMLLRNLVENAHRYSPQGSNIMIKLQEDGGAIMAVEDEGPGIDESKCGELSKAFVRMDSRYGGIGL
GLSIVSRITQLHHGQFFLQNRQETSGTRAWIRLKKDQYVANQI

Sequences:

>Translated_363_residues
MRFLRRPISLRQRLILTIGAILLVFELISVFWLWHESTEQIQLFEQALRDNRNNDRHIMREIREAVASLIVPGVFMVSLT
LFICYQAVRRITRPLAELQKELEARTADNLTPIAIHSATLEIDAVVSALNDLVSRLTSTLDNERLFTADVAHELRTPLAG
VRLHLELLAKTHHIDVAPLVARLDQMMESVSQLLQLARAGQSFSSGNYQHVKLLEDVILPSYDELSTMLDQRQQTLLLPE
SAADITVQGDATLLRMLLRNLVENAHRYSPQGSNIMIKLQEDGGAIMAVEDEGPGIDESKCGELSKAFVRMDSRYGGIGL
GLSIVSRITQLHHGQFFLQNRQETSGTRAWIRLKKDQYVANQI
>Mature_363_residues
MRFLRRPISLRQRLILTIGAILLVFELISVFWLWHESTEQIQLFEQALRDNRNNDRHIMREIREAVASLIVPGVFMVSLT
LFICYQAVRRITRPLAELQKELEARTADNLTPIAIHSATLEIDAVVSALNDLVSRLTSTLDNERLFTADVAHELRTPLAG
VRLHLELLAKTHHIDVAPLVARLDQMMESVSQLLQLARAGQSFSSGNYQHVKLLEDVILPSYDELSTMLDQRQQTLLLPE
SAADITVQGDATLLRMLLRNLVENAHRYSPQGSNIMIKLQEDGGAIMAVEDEGPGIDESKCGELSKAFVRMDSRYGGIGL
GLSIVSRITQLHHGQFFLQNRQETSGTRAWIRLKKDQYVANQI

Specific function: Member of the two-component regulatory system BasS/BasR Autophosphorylates and activates BasR by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790551, Length=363, Percent_Identity=98.6225895316804, Blast_Score=729, Evalue=0.0,
Organism=Escherichia coli, GI1789403, Length=276, Percent_Identity=32.2463768115942, Blast_Score=98, Evalue=9e-22,
Organism=Escherichia coli, GI1789808, Length=270, Percent_Identity=27.7777777777778, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1786783, Length=303, Percent_Identity=27.7227722772277, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788393, Length=259, Percent_Identity=29.3436293436293, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1786600, Length=199, Percent_Identity=31.1557788944724, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1790346, Length=231, Percent_Identity=26.8398268398268, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI87081816, Length=354, Percent_Identity=25.4237288135593, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788279, Length=292, Percent_Identity=28.4246575342466, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1787894, Length=214, Percent_Identity=30.8411214953271, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787374, Length=254, Percent_Identity=27.1653543307087, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 41005; Mature: 41005

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFLRRPISLRQRLILTIGAILLVFELISVFWLWHESTEQIQLFEQALRDNRNNDRHIMR
CCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHH
EIREAVASLIVPGVFMVSLTLFICYQAVRRITRPLAELQKELEARTADNLTPIAIHSATL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHH
EIDAVVSALNDLVSRLTSTLDNERLFTADVAHELRTPLAGVRLHLELLAKTHHIDVAPLV
HHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHH
ARLDQMMESVSQLLQLARAGQSFSSGNYQHVKLLEDVILPSYDELSTMLDQRQQTLLLPE
HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHEECCC
SAADITVQGDATLLRMLLRNLVENAHRYSPQGSNIMIKLQEDGGAIMAVEDEGPGIDESK
CCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEECCCCCCCHHH
CGELSKAFVRMDSRYGGIGLGLSIVSRITQLHHGQFFLQNRQETSGTRAWIRLKKDQYVA
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCHHHEEECCHHHHH
NQI
CCC
>Mature Secondary Structure
MRFLRRPISLRQRLILTIGAILLVFELISVFWLWHESTEQIQLFEQALRDNRNNDRHIMR
CCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHH
EIREAVASLIVPGVFMVSLTLFICYQAVRRITRPLAELQKELEARTADNLTPIAIHSATL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHH
EIDAVVSALNDLVSRLTSTLDNERLFTADVAHELRTPLAGVRLHLELLAKTHHIDVAPLV
HHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHH
ARLDQMMESVSQLLQLARAGQSFSSGNYQHVKLLEDVILPSYDELSTMLDQRQQTLLLPE
HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHEECCC
SAADITVQGDATLLRMLLRNLVENAHRYSPQGSNIMIKLQEDGGAIMAVEDEGPGIDESK
CCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEECCCCCCCHHH
CGELSKAFVRMDSRYGGIGLGLSIVSRITQLHHGQFFLQNRQETSGTRAWIRLKKDQYVA
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCHHHEEECCHHHHH
NQI
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8282725; 7610040; 9278503 [H]